The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4

Genomics

Volumn 40, Issue 1, 1997, Pages 196-198

  DiLeone, Ralph J ^a   King, Jennifer A ^a   Storm, Elaine E ^a   Copeland, Neal G ^b   Jenkins, Nancy A ^b   Kingsley, David M ^a  

^a STANFORD UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CHROMOSOMAL LOCALIZATION; CHROMOSOME 4; EMBRYO; GENE LOCATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0031568894     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.4533     Document Type: Article

References (15)

1. 1. Briggs, M. D., Choi, H., Warman, M. L., Loughlin, J. A., Wordsworth, P., Sykes, B. C., and Irven, C. M. (1994). Genetic mapping of a locus for multiple epiphyseal dysplasia (EDM2) to a region of chromosome 1 containing a type IX collagen gene. Am. J. Hum. Genet. 55: 678-684.
2. 2. Copeland, N. G., and Jenkins, N. A. (1991). Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet. 7: 113-118.
3. 3. Haefliger, J. A., Bruzzone, R., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., and Paul, D. L. (1992). Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping. J. Biol. Chem. 267: 2057-2064.
4. 4. Hogan, B. L. M. (1996). Bone morphogenetic proteins: Multifunctional regulators of vertebrate development. Genes Dev. 10: 1580-1594.
5. 5. King, J. A., Marker, P. C., Seung, K. J., and Kingsley, D. M. (1994). BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice. Dev. Biol. 166: 112-122.
6. 6. Kingsley, D. M. (1994). What do BMPs do in mammals? Clues from the mouse short-ear mutation. Trends Genet. 10: 16-21.
7. 7. Kingsley, D. M. (1994). The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8: 133-146.
8. 8. Konyukhov, B. V., and Paschin, Y. V. (1970). Abnormal growth of the body, internal organs and skeleton in the achondroplasia mice. Acta Biol. Acad. Sci. Hung. 21: 347-354.
9. 9. Lyon, M. F., and Searle, A. G. (1989). "Genetic Strains and Variants of the Laboratory Mouse," 2nd ed., Oxford Univ. Press, Oxford.
10. 10. Muragaki, Y., Mariman, E. C., van Beersum, S. E., Perala, M., van Mourik, J. B., and Warman, M. L. (1996). A mutation in the gene encoding the alpha 2 chain of the fibril-associated collagen IX, COL9A2, causes multiple epiphyseal dysplasia (EDM2). Nature Genet. 12: 103-105.
11. 11. Ozkaynak, E., Schnegelsberg, P. N. J., Jin, D. J., Clifford, G. M., Warren, F. D., Drier, E. A., and Oppermann, H. (1992). Osteogenic protein-2: A new member of the transforming growth factor-β superfamily expressed early in development. J. Biol. Chem. 267: 25220-25227.
12. 12. Rosen, V., and Thies, R. S. (1992). The BMP proteins in bone formation and repair. Trends Genet. 8: 97-102.
13. 13. Sciaky, D., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Sonoda, G., Testa, J. R., and Cohen, M. B. (1995). Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35. Genomics 26: 427-429.
14. 14. Zhao, G.-Q., Deng, K., Labosky, P. A., Liaw, L., and Hogan, B. L. M. (1996). The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse. Genes Dev. 10: 1657-1669.
15. 15. Zhao, G.-Q., and Hogan, B. L. M. (1996). Evidence that mouse Bmp8 (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development. Mech Dev. 57: 159-168.