Selective induction of phase II drug metabolizing enzyme activities by quinolines and isoquinolines

Chemico-Biological Interactions

Volumn 103, Issue 3, 1997, Pages 167-178

  Le, Hau T ^a   Franklin, Michael R ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Chloroquine; Drug metabolism; Phase II induction; Quinine; Quinolines

Indexed keywords

4 NITROPHENOL; CHLOROQUINE; CYTOCHROME P450 ISOENZYME; DRUG METABOLIZING ENZYME; EPOXIDE HYDROLASE; ESTRONE; ETHOXYRESORUFIN DEETHYLASE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; ISOQUINOLINE; MORPHINE; OXIDOREDUCTASE; QUININE; QUINOLINE; TESTOSTERONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INDUCTION; INTRAGASTRIC DRUG ADMINISTRATION; MALE; NONHUMAN; RAT;

ANIMALS; CHLOROQUINE; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSOL; ENZYME INDUCTION; EPOXIDE HYDROLASES; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; ISOQUINOLINES; LIVER; MALE; MICROSOMES, LIVER; NAD(P)H DEHYDROGENASE (QUINONE); PHARMACEUTICAL PREPARATIONS; QUININE; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031567152     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(96)03755-6     Document Type: Article

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