Immunologic effects of cocaine in prenatally exposed rats and mice

Toxicology Letters

Volumn 91, Issue 1, 1997, Pages 47-55

  Bohn, Andrea A ^a   Forsyth, Carol S ^b   Kerkvliet, Nancy I ^c   Frank, Anthony A ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c OREGON STATE UNIVERSITY   (United States)

Author keywords

Cocaine; Immunotoxicity; Prenatal exposure

Indexed keywords

COCAINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; FETUS; IMMUNOTOXICITY; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, CD3; B-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; COCAINE; FEMALE; FLOW CYTOMETRY; HEMOCYANIN; HYPERSENSITIVITY, DELAYED; IMMUNE SYSTEM; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MICE; MICE, INBRED C57BL; NARCOTICS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; THYMUS GLAND;

EID: 0031567129     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(96)03867-2     Document Type: Article

References (39)

1. [1] National Institute on Drug Abuse. (1992) National Household Survey on Drug Abuse: Population Estimates 1992. US Department of Health and Human Services, Rockville, MD, p. 31.
2. [2] Gomby, D.S. and Shiono, P.H. (1991) Estimating the number of substance-exposed infants. Future Child 1, 17-25.
3. [3] Holzman, C. and Paneth, N. (1994) Maternal cocaine use during pregnancy and perinatal outcomes. Epidemiol. Rev. 16, 315-334.
4. [4] Ostrea, E.M. Jr., Brady, M., Gause, S., Raymundo, A.L. and Stevens, M. (1992) Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study. Pediatrics 89, 107-113.
5. [5] Bagasra, O. and Forman, L. (1989) Functional analysis of lymphocytes subpopulations in experimental cocaine abuse. I. Dose-dependent activation of lymphocyte subsets. Clin. Exp. Immunol. 77, 289-293.
6. [6] DiFrancesco, P., Marini, S., Pica, F., Favalli, C., Tubaro, E. and Garaci, E. (1992) In vivo cocaine administration influences lymphokine production and humoral immune response. Immunol. Res. 11, 74-79.
7. [7] DiFrancesco, P., Pica, F., Croce, C., Favalli, C., Tubaro, E. and Garaci, E. (1990) Effect of acute or daily cocaine administration of cellular immune response and virus infection in mice. Nat. Immun. Cell Growth Regul. 9, 397-405.
8. [8] Donahoe, R.M., Falek, A., Madden, J.J., Nicholson, J.K.A., Bokos, P., Gallegos, K. and Veit, R. (1991) Effects of cocaine and other drugs of abuse on immune function. Drugs of Abuse, Immunity and Immunodeficiency 143-150.
9. [9] Havas, H.F., Dellaria, M., Schiffman, G., Geller, E.B. and Adler, M.W. (1987) Effect of cocaine on the immune response and host resistance in BALB/c mice. Int. Arch. Allergy Appl. Immunol. 83, 377-383.
10. [10] Ou, D.W., Shen, M.-L. and Luo, Y.-D. (1989) Effects of cocaine on the immune system of BALB/c mice. Clin. Immunol. Immunopathol. 52, 305-312.
11. [11] Pacifici, R., Avico, U., Belogi, L., Borelli, G., Croce, C., DiCarlos, S., Pichini, S., Santiangeli, C., Zuccaro, P. and Tubaro, E. (1992) Immunological effect of cocaine and host resistance in mice. Int. J. Immunother. 8, 91-99.
12. [12] Sobrian, S.K., Burton, L.E., Robinson, N.L., Ashe, W.K., James, H., Stokes, D.L. and Turner, L.M. (1990) Neurobehavioral and immunological effects of prenatal cocaine exposure in rat. Pharmacol. Biochem. Behav. 35, 617-629.
13. [13] Starec, M., Rouveix, B., Sinet, M., Chau, F., Desforges, B., Pocidalo, J. and Lechat, P. (1991) Immune status and survival of opiate-and cocaine-treated mice infected with friend virus. J. Pharmacol. Exp. Ther. 259, 745-750.
14. 9-tetrahydrocannabinol and ethanol. Toxicol. Appl. Pharmacol. 71, 1-13.
15. [15] Watzl, B., Chen, G., Scuderi, P., Pirozhkov, S. and Watson, R.R. (1992) Cocaine-induced suppression of interferon-gamma secretion in leukocytes from young and old C57BL/6 mice. Int. J. Immunopharmacol. 14, 1125-1131.
16. [16] Lopez, M.C., Chen, G.-J., Huang, D.S., Wang, Y. and Watson, R.R. (1992) Modification of spleen cell subsets by chronic cocaine administration and murine retrovirus infection in normal and protein malnourished mice. Int. J. Immunopharmacol. 14, 1153-1163.
17. [17] Lopez, M.C., Colombo, L.L., Huang, D.S., Wang, Y. and Watson, R.R. (1992) Modification of thymic cell subsets induced by long-term cocaine administration during a murine retroviral infection producing AIDS. Clin. Immunol. Immunopathol. 65, 45-52.
18. [18] Lopez, M.C. and Watson, R.R. (1994) Effect of cocaine and murine AIDS on lamina propria T and B cells in normal mice. Life Sci. 54, 147-151.
19. [19] Ruiz, P., Cleary, T., Nassiri, M. and Steele, B. (1994) Human T lymphocyte subpopulation and NK cell alterations in persons exposed to cocaine. Clin. Immunol. Immunopathol. 70, 245-250.
20. [20] Chen, G., Tachibana, K., Huang, D.S. and Watson, R.R. (1993) Cocaine modulation in vitro of tumor necrosis factor production by macrophages from retrovirally infected mice. Life Sci. 52, 1641-1647.
21. [21] Donohue, R.M., Nicholson, J.K.A., Madden, J.J., Donohue, F., Shafer, D.A., Gordon, D., Bokos, P. and Falek, A. (1986) Coordinate and independent effects of heroin, cocaine, and alcohol abuse on T-cell E-Rosette formation and antigen marker expression. Clin. Immunol. Immunopathol. 41, 254-264.
22. [22] Peterson, P.K., Gekker, G., Chao, C.C., Schut, R., Molitor, T.W. and Balfour, N.H. (1991) Cocaine potentiates HIV-1 replication in human peripheral blood mononuclear cell cocultures. Involvement of transforming growth factor-β. J. Immunol. 146, 81-84.
23. [23] Chasnoff, I.J., Chisum, G.M. and Kaplan, W.E. (1988) Maternal cocaine use and genitourinary tract malformations. Teratology 37, 201-204.
24. [24] Klein, T.W., Newton, C. and Friedman, H. (1988) Suppression of human and mouse lymphocyte proliferation by cocaine. Adv. Biochem. Psychopharmacol. 44, 139-143.
25. [25] Klein, T.W., Newton, C. and Friedman, H. (1991) Cocaine effects on cultured lymphocytes. Drugs of Abuse, Immunity and Immunodeficiency 151-158.
26. [26] Matsui, K., Friedman, H. and Klein, T.W. (1992) Cocaine augments proliferation of human peripheral blood T-lymphocytes activated with anti-CD3 antibody. Int. J. Immunopharmacol. 14, 1213-1220.
27. [27] Lyman, W.D. (1993) Perinatal AIDS: drugs of abuse and transplacental infection. Drugs of Abuse, Immunity, and AIDS 211-217.
28. [28] Cunningham, A.J. and Szenberg, A. (1968) Further improvements in the plaque technique for detecting single antibody forming cells. Immunology 14, 599-600.
29. [29] Exon, J.H., Bussiere, J.L. and Williams, J.R. (1990) Hypophysectomy and growth hormone replacement effects on multiple immune responses in rats. Brain Behav. Immun. 4, 118-128.
30. [30] Kruisbeek, A.M. and Shevach, E. (1994) Proliferative assays for T celi function. In: J.E. Coligan, A.M. Kruisbeek, D.H. Margulies, E.M. Shevach and W. Strober (Eds.), Current Protocols in Immunology, vol. 1, Current Protocols, pp. 3.12.9-3.12.10.
31. [31] Temple, L., Kawabata, T.T., Munson, A.E. and White, K.L. Jr. (1993) Comparison of ELISA and plaque-forming cell assays for measuring the humoral immune response to SRBC in rats and mice treated with benzo[a]pyrene or cyclophosphamide. Fundam. Appl. Toxicol. 21, 412-419.
32. [32] Faith, R.E. and Valentine, J.L. (1983) Effects of cocaine exposure on immune function (abstract). Toxicologist 3, 56.
33. [33] Masten, S.A., Millard, W.J., Karlix, J.L. and Shiverick, K.T. (1996) Evaluation of immune parameters and lymphocyte production of prolactin-immunoreactive proteins after chronic administration of cocaine to pregnant rats. J. Pharmacol. Exp. Ther. 277, 1090-1096.
34. [34] Martinez, F. and Watson, R.R. (1990) Effects of cocaine and morphine on IgG production by human peripheral blood lymphocytes in vitro. Life Sci. 47, 59-64.
35. [35] Bayer, B.M., Mulroney, S.E., Hernandez, M.C. and Ding, X.Z. (1995) Acute infusions of cocaine result in time-and dose-dependent effects on lymphocyte responses and corticosterone secretion in rats. Immunopharmacology 29, 19-28.
36. [36] Moldow, R.L. and Fischman, A.J. (1987) Cocaine induced secretion of ACTH, beta-endorphin, and corticosterone. Peptides 8, 819-822.
37. [37] DiFrancesco, P., Falchetti, R., Gaziano, R., Lanzilli, G., Belogi, L., Ravagnan, G. and Garaci, E. (1994) Differential effects of short-term or prolonged cocaine exposure on peripheral blood cells in mice. Life Sci. 54, 2015-2020.
38. [38] Van Dyke, C., Stesin, A., Jones, R., Chuntharapai, A. and Seaman, W. (1986) Cocaine increases natural killer cell activity. J. Clin. Invest. 77, 1387-1390.
39. [39] Watzl, B. and Watson, R.R. (1990) Immunomodulation by cocaine - a neuroendocrine mediated response. Life Sci. 46, 1319-1329.