X-ray structure at 1.76 Å resolution of a polypeptide phospholipase A2 inhibitor

Journal of Molecular Biology

Volumn 266, Issue 1, 1997, Pages 160-172

  Devedjiev, Yancho ^a,b,c   Popov, Alexander ^a   Atanasov, Boris ^b   Bartunik, Hans Dieter ^a  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^b BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Molecular evolution; Neurotoxin; Phospholipase A2 inhibitor; Recognition; X ray structure

Indexed keywords

NEUROTOXIN; PHOSPHOLIPASE A2 INHIBITOR; POLYPEPTIDE; VIPER VENOM;

AMINO ACID SEQUENCE; ARTICLE; HYDROPHOBICITY; MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; R FACTOR; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

EID: 0031566961     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0778     Document Type: Article

References (52)

1. Achari A., Radvanyi F., Scott D., Bon C, Sigler P. Crystals of crotoxin suitable for high resolution X-ray diffraction analysis. J. Biol. Chem. 260:1981;9385-9387.
2. Aird S., Kaiser R., Lewis V., Kruggell W. Rattlesnake presynaptic neurotoxins: primary structure and evolutionary origin of the acidic subunit. Biochemistry. 24:1985;7054-7058.
3. 2from the venom of Bulgarian viper (Vipera ammodytes ammodytes). Toxicon. 14:1976;477-485.
4. Bernstein F. C., Koetzle T. F., Williams G. J. B., Meyer E. F. Jr., Brice M. D., Rodgers J. R., Kenard O., Shimanouchi T., Tasumi M. The Protein Data Bank: a computer-based archival file for macromolecular structures. J. Mol. Biol. 112:1977;535-542.
5. Beshkov, V. 1973, PhD thesis, Institute of Zoology, Sofia.
6. 2and its natural polypeptide inhibitor. J. Mol. Biol. 231:1993;498-500.
7. Blinov N., Tchorbanov B., Grishin B., Aleksiev B. Neurotoxic action of a protein complex from the venom of the Bulgarian viper (Vipera ammodytes ammodytes). C.R.Acad. Bull. Sci. 32:1979;663-666.
8. Bode W., Turk D., Karshikov A. The refined 1.9 Å X-ray structure of D -Phe-Pro-Arg chlormethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active site geometry and structure-function relationships. Protein Sci. 1:1992;426-471.
9. Bon C., Changeux J.-P., Jeng T.-W., Fraenkel-Conrat H. Postsynaptic effects of crotoxin and its isolated subunits. J. Biochem. 99:1979;471-481.
10. Bradley, J. 1993, XV Version 3.0, 000, 000.
11. 2at 2.5 Å J. Biol. Chem. 260:1985;9742-9749.
12. Brünger A. T. X-PLOR (Version 3.1) Manual. 1992;Yale University Press, New Haven and London.
13. Bukolova-Orlova T., Burstein E., Chorbanov B., Aleksiev B., Atansov B. Study of some properties of the neurotoxic complex and its componenets from the venom of Bulgarian sand viper, Vipera ammodytes ammodyres I. Luminescence of tryptophan residues. Biochem. Biophys. Acta. 577:1979;44-51.
14. Bukolova-Orlova T., Orlov N., Burstein E., Chorbanov B., Aleksiev B. Study of the neurotoxic complex and its components from the venom of the Bulgarian sand viper (Vipera ammodytes ammodytes). Arch. Biochem. Biophys. 200:1980;216-222.
15. Buresh I., Tzonkov J. Studies on distribition of the reptiles and amphibia in Bulgaria and over the Balkan peninsula. P.II. Snakes. The Bulletin of Tzar's Institutes of Natural History in Sofia. 1934.
16. Chang C., Lee J. Crotoxin, the neurotoxin of south american rattlesnake venom, is a presynaptic toxin acting like β-bungarotoxin. Naunyn-Schmiedeberg's Arch. Pharmacol. 296:1977;159-168.
17. Devedjiev Y., Mancheva I., Aleksiev B., Atanasov B. Solubility and phase states of vipoxin from the venom of Bulgarian viper (Vipera ammodytes ammodytes). C.R.Acad. Bull. Sci. 42:1989;91-94.
18. 2inhibitor. The non-toxic component of vipoxin from the venom of Bulgarian viper (Vipera ammodytes). J. Mol. Biol. 229:1993;1147-1148.
19. 2. Nature. 289:1981a;604-606.
20. 2at 1.7 Å resolution. J. Mol. Biol. 147:1981b;97-123.
21. Hanley M. Crotoxin effects on Torpedo californica cholinergic excitable vesicles and the role of its phospholipase A activity. Biochem. Biophys. Res. Commun. 82:1978;392-401.
22. Hawgood B., Smith J. The mode of action at the mouse neuromuscular junction of the phospholipase A-crotapotin complex isolated from the venom of the South American rattlesnake. Br. J. Pharmacol. 61:1977;597-606.
23. Hendon R., Fraenkel-Conrat H. Biological role of the two components of crotoxin. Proc. Natl Acad. Sci. USA. 68:1971;1560-1563.
24. Janin J., Miller S., Chothia C. Surfaces, subunit interfaces and interior of oligomeric proteins. J. Mol. Biol. 204:1988;155-164.
25. Jones T. A., Zou J.-Y., Cowan S. W., Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallog. sect. A. 47:1991;110-119.
26. Kabsch W., Sander Ch. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers. 22:1983;2577-2537.
27. 2from the venom of Crotalus artrox. J. Biol. Chem. 256:1981;8602-8607.
28. Kraulis J. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallog. 24:1991;946-950.
29. Krizaj I., Turk D., Ritonja A., Gubensek F. Primary structure of ammodytoxin C further reveals the toxic site of ammodytoxin. Biochim. Biophys. Acta. 999:1989;198-202.
30. Laskovski R., Macarthur M., Moss D., Thornton J. Procheck: a program to check stereochemical quality of protein structures. J. Appl. Crystallog. 26:1993;283-290.
31. Luzzati V. Traitement statistique des erreurs dans la determination des structures cristallines. Acta Cystallog. 5:1952;802-810.
32. Mancheva I., Kleinschmidt T., Aleksiev B., Braunitzer G. Sequence homology between phospholipase and its inhibitor in snake venom. The primary structure of the inhibitor of vipoxin from the venom of the Bulgarian viper (Vipera ammodytes ammodytes). Hoppe-Seyler Z. Physiol. Chem. 356:1984;885-894.
33. 2of vipoxin from the venom of Bulgarian viper (Vipera ammodytes ammodytes). Hoppe-Seyler Z. Physiol. Chem. 368:1987;343-352.
34. Matthews B. Solvent content of protein crystals. J. Mol. Biol. 33:1968;491-497.
35. Messerchmidt A., Pflugrath J. Crystal orientation and X-ray pattern prediction routines for area detector diffractometer system in macromolecular crystallography. J. Appl. Crystallog. 20:1987;306-316.
36. Navaza J. AMoRe: an automated package for molecular replacement. Acta Crystallog. Sect. A,50:1994;157-163.
37. North A. C., Phillips D. C., Mathews F. S. A semi-empirical method of absorption correction. Acta Crystallog. sect. A. 24:1968;351-359.
38. Popov A. N., Andrianova M., Burenkov G., Kheiker D. M. A method for data collection for macromolecular crystals on KARD-6 X-ray diffractometer, supplied with two-dimensional multiwire detector. Kristallografiya. 39:1994;415-421.
39. 2from bovine pancreas and Crotalus atrox venom. J. Biol. Chem. 260:1985;11627-11634.
40. 2from Vipera ammodytes ammodytes venom. Biochim. Biophys. Acta. 828:1985;306-312.
41. Ritonja A., Machleidt W., Turk V., Gubensek F. Amino acid sequence of ammodytoxin B partially reveals the location of the site of toxicity of ammodytoxins. Biol. Chem. Hoppe-Seyler. 367:1986;919-923.
42. 2. Science. 250:1990a;1541-1546.
43. 2in a complex with a transition state analog. Science. 250:1990b;1563-1566.
44. 2from inflammatory exudate. Science. 254:1991;1007-1012.
45. Tchorbanov B., Aleksiev B. A simple procedure for the isolation of vipoxin - a neurotoxin with weak phospholipase activity from the venom of the Bulgarian viper (Vipera ammodytes ammodytes). J. Appl. Biochem. 3:1981;558-561.
46. 2. Toxicon. 16:1978;37-44.
47. Vagin, A. A. 1983, Use of the non-crystallographic symmetry in structural protein crystallography. PhD Thesis, Institute of Crystallography, Moscow.
48. 2from Taiwan viper (Vipera russeli formosensis). Eur. J. Biochem. 209:1992;635-641.
49. 2at 2.2 Å resolution. Nature. 352:1991;79-82.
50. 2at 2.0 Å resolution. FEBS Letters. 301:1992;159-164.
51. 2in a complex with a transition state analog. Science. 250:1990;1560-1563.
52. Zanevsky Yu. V., Donets D. E., Ivanov A. B., Movhan S. A., Ostrovnoj A. I., Chernenko S. P., Kheiker D. M., Andrianova M. E., Popov A. N., Sulyanov S. N. Two-dimensional multiwire detector of high resolution for X-ray diffractometer. Kristallografiya. 38:1993;284-292.