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Volumn 395, Issue 2-3, 1997, Pages 229-242

Genotoxic activation of hydrazine, two dialkylhydrazines, thiourea and ethylene thiourea in the somatic w/w + assay of Drosophila melanogaster

Author keywords

Biotransformation; CYP450 enzyme; Drosophila melanogaster; Insecticide resistant strain; Insecticide susceptible strain; Somatic in vivo w w + assay

Indexed keywords

1,2 DIMETHYLHYDRAZINE; 2 IMIDAZOLIDINETHIONE; CYTOCHROME P450; HYDRAZINE; HYDRAZINE DERIVATIVE; THIOUREA;

EID: 0031565987     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(97)00159-9     Document Type: Article
Times cited : (4)

References (35)
  • 1
    • 0027534655 scopus 로고
    • Performance of 181 chemicals in a Drosophila assay predominantly monitoring interchromosomal mitotic recombination
    • Vogel E.W., Nivard M.J.M. Performance of 181 chemicals in a Drosophila assay predominantly monitoring interchromosomal mitotic recombination. Mutagenesis. 8:1993;57-81.
    • (1993) Mutagenesis , vol.8 , pp. 57-81
    • Vogel, E.W.1    Nivard, M.J.M.2
  • 2
    • 0025776202 scopus 로고
    • Variation of spontaneous and induced mitotic recombination in different Drosophila populations: A pilot study on the effects of polyaromatic hydrocarbons in six newly constructed tester strains
    • Vogel E.W., Nivard M.J.M., Zijilstra J.A. Variation of spontaneous and induced mitotic recombination in different Drosophila populations: a pilot study on the effects of polyaromatic hydrocarbons in six newly constructed tester strains. Mutation Res. 250:1991;291-298.
    • (1991) Mutation Res. , vol.250 , pp. 291-298
    • Vogel, E.W.1    Nivard, M.J.M.2    Zijilstra, J.A.3
  • 3
    • 0027134983 scopus 로고
    • Strong intra-species variability in the metabolic conversion of six procarcinogens to somatic cell recombinagens in Drosophila
    • Rodriguez-Arnaiz R., Vogel E.W., Szakmary A. Strong intra-species variability in the metabolic conversion of six procarcinogens to somatic cell recombinagens in Drosophila. Mutagenesis. 8:1993;543-551.
    • (1993) Mutagenesis , vol.8 , pp. 543-551
    • Rodriguez-Arnaiz, R.1    Vogel, E.W.2    Szakmary, A.3
  • 4
    • 0028850384 scopus 로고
    • An empirical and theoretical study on mechanisms of mutagenic activity of hydrazine compounds
    • Poso A., von Wright A., Gynther J. An empirical and theoretical study on mechanisms of mutagenic activity of hydrazine compounds. Mutation Res. 332:1995;63-71.
    • (1995) Mutation Res. , vol.332 , pp. 63-71
    • Poso, A.1    Von Wright, A.2    Gynther, J.3
  • 5
    • 0017493879 scopus 로고
    • On the occurrence of N-methyl-N-formyl hydrazones in fresh and processed false morel Gyromitra esculenta
    • Pyysalo H., Niskanen A. On the occurrence of N-methyl-N-formyl hydrazones in fresh and processed false morel Gyromitra esculenta. J. Agric. Food Chem. 25:1977;644-647.
    • (1977) J. Agric. Food Chem. , vol.25 , pp. 644-647
    • Pyysalo, H.1    Niskanen, A.2
  • 6
    • 0020131966 scopus 로고
    • Evidence for the ocurrence and formation of diazonium ions in Agaricus bisporus mushroom and its extracts
    • Ross D., Nagel B., Toth A. Evidence for the ocurrence and formation of diazonium ions in Agaricus bisporus mushroom and its extracts. Agric. Food Chem. 30:1982;521-525.
    • (1982) Agric. Food Chem. , vol.30 , pp. 521-525
    • Ross, D.1    Nagel, B.2    Toth, A.3
  • 9
    • 0027409604 scopus 로고
    • Mutagenicity of alkylhydrazine oxalates in Salmonella typhimurium TA100 and TA102 demonstrated by modifying the growth conditions of the bacteria
    • Matsushita H., Endo O., Matsushita H., Yamamoto M., Mochizuki M. Mutagenicity of alkylhydrazine oxalates in Salmonella typhimurium TA100 and TA102 demonstrated by modifying the growth conditions of the bacteria. Mutation Res. 301:1993;213-222.
    • (1993) Mutation Res. , vol.301 , pp. 213-222
    • Matsushita, H.1    Endo, O.2    Matsushita, H.3    Yamamoto, M.4    Mochizuki, M.5
  • 10
    • 0023191830 scopus 로고
    • Carcinogenesis by nitrosodialkylamines and azoxyalkanes given by gavage to rats and hamsters
    • Linsky W., Kovatch R.M., Riggs C.W. Carcinogenesis by nitrosodialkylamines and azoxyalkanes given by gavage to rats and hamsters. Cancer Res. 47:1987;3968-3972.
    • (1987) Cancer Res. , vol.47 , pp. 3968-3972
    • Linsky, W.1    Kovatch, R.M.2    Riggs, C.W.3
  • 11
    • 0020621777 scopus 로고
    • Metabolism of the carcinogen 1,2-dimethylhydrazine by isolated human microsomes and human colon tumor cells in culture
    • Newaz S.N., Fang W., Strobel H.W. Metabolism of the carcinogen 1,2-dimethylhydrazine by isolated human microsomes and human colon tumor cells in culture. Cancer. 52:1983;794-798.
    • (1983) Cancer , vol.52 , pp. 794-798
    • Newaz, S.N.1    Fang, W.2    Strobel, H.W.3
  • 12
    • 0027235563 scopus 로고
    • Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas
    • Davidson N.O., Ifkovits C.A., Skarosi S.F., Hausman A.M., Lor X., Sitrin M.D., Montag A., Brasitus T.A. Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas. Lab. Invest. 68:1993;663-675.
    • (1993) Lab. Invest. , vol.68 , pp. 663-675
    • Davidson, N.O.1    Ifkovits, C.A.2    Skarosi, S.F.3    Hausman, A.M.4    Lor, X.5    Sitrin, M.D.6    Montag, A.7    Brasitus, T.A.8
  • 13
    • 0026342815 scopus 로고
    • Characterization of cytochrome P450 dependent dimethylhydrazine metabolism in human colon microsomes
    • Stralka D., Strobel H.W. Characterization of cytochrome P450 dependent dimethylhydrazine metabolism in human colon microsomes. Cancer. 68:1991;2363-2369.
    • (1991) Cancer , vol.68 , pp. 2363-2369
    • Stralka, D.1    Strobel, H.W.2
  • 14
    • 0027207964 scopus 로고
    • Carbon-centered free radical formation during the metabolism of hydrazine derivatives by neutrophils
    • Gamberini M., Leite L.C. Carbon-centered free radical formation during the metabolism of hydrazine derivatives by neutrophils. Biochem. Pharmacol. 45:1993;1913-1919.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 1913-1919
    • Gamberini, M.1    Leite, L.C.2
  • 15
    • 0026748369 scopus 로고
    • Oxidation of methylhydrazines to mutagenic methylating derivatives and inducers of the adaptative response of Escherichia coli to alkylation damage
    • Sedgwick B. Oxidation of methylhydrazines to mutagenic methylating derivatives and inducers of the adaptative response of Escherichia coli to alkylation damage. Cancer Res. 52:1992;3693-3697.
    • (1992) Cancer Res. , vol.52 , pp. 3693-3697
    • Sedgwick, B.1
  • 16
    • 0029988163 scopus 로고    scopus 로고
    • Mutagenicity and toxicity of the DNA alkylation carcinogens 1,2-dimethylhydrazine and azoxymethane in Escherichia coli and Salmonella typhimurium
    • Xiao W., Nowak M., Laferte S., Fontanie T. Mutagenicity and toxicity of the DNA alkylation carcinogens 1,2-dimethylhydrazine and azoxymethane in Escherichia coli and Salmonella typhimurium. Mutagenesis. 11:1996;241-245.
    • (1996) Mutagenesis , vol.11 , pp. 241-245
    • Xiao, W.1    Nowak, M.2    Laferte, S.3    Fontanie, T.4
  • 17
    • 0001421478 scopus 로고
    • Hydrazine derivatives, azo and azoxy compounds, and methylazoxymethanol and cycasin
    • S. Searle (Ed.) American Chemical Society, Washington, DC
    • M.S. Zedeck, Hydrazine derivatives, azo and azoxy compounds, and methylazoxymethanol and cycasin, in: S. Searle (Ed.), Chemical Carcinogens, American Chemical Society, Washington, DC, 1984, pp. 915-944.
    • (1984) Chemical Carcinogens , pp. 915-944
    • Zedeck, M.S.1
  • 18
    • 0026539913 scopus 로고
    • Carcinogenesis induced by a single administration of 1,2-diethylhydrazine in female rats of various ages
    • Anasimov V.N. Carcinogenesis induced by a single administration of 1,2-diethylhydrazine in female rats of various ages. Cancer Lett. 67:1992;21-25.
    • (1992) Cancer Lett. , vol.67 , pp. 21-25
    • Anasimov, V.N.1
  • 19
    • 85041991619 scopus 로고
    • Selected specific rates of reactions of transitiens from water in aqueous solutions : III Hydroxil radical and perhydrpxyl radical and their radical ions
    • Farhataziz A., Ross B. Selected specific rates of reactions of transitiens from water in aqueous solutions. III Hydroxil radical and perhydrpxyl radical and their radical ions Natl. Stand. Ref. Ser. 58:1977;1-113.
    • (1977) Natl. Stand. Ref. Ser. , vol.58 , pp. 1-113
    • Farhataziz, A.1    Ross, B.2
  • 20
    • 0025742690 scopus 로고
    • Cytocidal and filamentous response of Escherichia coli cells exposed to low concentrations of hydrogen peroxide and hydroxyl radical scavengers
    • Brandi G., Salvaggio L., Cattabeni F., Cantoni O. Cytocidal and filamentous response of Escherichia coli cells exposed to low concentrations of hydrogen peroxide and hydroxyl radical scavengers. Environ. Mol. Mutagen. 18:1991;22-27.
    • (1991) Environ. Mol. Mutagen. , vol.18 , pp. 22-27
    • Brandi, G.1    Salvaggio, L.2    Cattabeni, F.3    Cantoni, O.4
  • 21
    • 0025986144 scopus 로고
    • Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system
    • Guo Z., Smith T.J., Ishizaki H., Yang C.S. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system. Carcinogenesis. 12:1991;2277-2282.
    • (1991) Carcinogenesis , vol.12 , pp. 2277-2282
    • Guo, Z.1    Smith, T.J.2    Ishizaki, H.3    Yang, C.S.4
  • 22
    • 0025743515 scopus 로고
    • Genotoxicity studies with the unstable zeste-white (UZ) system of Drosophila melanogaster: Results with ten carcinogen compounds
    • Batiste-Alentorn M., Xamena N., Creus A., Marcos R. Genotoxicity studies with the unstable zeste-white (UZ) system of Drosophila melanogaster: results with ten carcinogen compounds. Environ. Mol. Mutagen. 18:1991;120-125.
    • (1991) Environ. Mol. Mutagen. , vol.18 , pp. 120-125
    • Batiste-Alentorn, M.1    Xamena, N.2    Creus, A.3    Marcos, R.4
  • 23
    • 0028835623 scopus 로고
    • The genetic toxicology of ethylenethiourea: A case study concerning the evaluation of a chemical's genotoxic potential
    • Elia C.M., Arce G., Hurt S.S., O'Neill P.J., Scribner H.E. The genetic toxicology of ethylenethiourea: a case study concerning the evaluation of a chemical's genotoxic potential. Mutation Res. 341:1995;141-149.
    • (1995) Mutation Res. , vol.341 , pp. 141-149
    • Elia, C.M.1    Arce, G.2    Hurt, S.S.3    O'Neill, P.J.4    Scribner, H.E.5
  • 24
    • 0010658293 scopus 로고
    • (feed studies) US Department of Health and Human Services, Public Health Service,National Institutes of Health, NIH publication no. 92-2843 March, National Toxicology ProgramTechical Report Series No. 388, March
    • NTP, National Toxicology Program, Toxicology and carcinogenesis studies of ethylenethiourea in F344/N rats and B6C3F1 mice (feed studies), US Department of Health and HumanServices, Public Health Service, National Institutes of Health, NIH publication no. 92-2843,National Toxicology Program Techical Report Series No. 388, March 1992.
    • (1992) Toxicology and Carcinogenesis Studies of Ethylene Thiourea in F344/N Rats and B6C3F1 Mice
  • 25
    • 77957174895 scopus 로고
    • Comparative carcinogenicity of ethylene thiourea with or without perinatal exposure in rats and mice
    • Chhabra R.S., Eustis S., Haseman J.K., Kurtz P.J., Carlton B.D. Comparative carcinogenicity of ethylene thiourea with or without perinatal exposure in rats and mice. Fund. Appl. Toxicol. 18:1992;405-417.
    • (1992) Fund. Appl. Toxicol. , vol.18 , pp. 405-417
    • Chhabra, R.S.1    Eustis, S.2    Haseman, J.K.3    Kurtz, P.J.4    Carlton, B.D.5
  • 28
    • 0009506575 scopus 로고
    • Ethylene thiourea (ETU). A review of the genetic toxicology studies
    • Dearfield K.L. Ethylene thiourea (ETU). A review of the genetic toxicology studies. Mutation Res. 317:1994;111-132.
    • (1994) Mutation Res. , vol.317 , pp. 111-132
    • Dearfield, K.L.1
  • 29
    • 0023618056 scopus 로고
    • Mechanistic and methodological aspects of chemically-induced somatic mutation and recombination in Drosophila melanogaster
    • Vogel E.W., Zjilstra J.A. Mechanistic and methodological aspects of chemically-induced somatic mutation and recombination in Drosophila melanogaster. Mutation Res. 182:1987;243-264.
    • (1987) Mutation Res. , vol.182 , pp. 243-264
    • Vogel, E.W.1    Zjilstra, J.A.2
  • 30
    • 0023630075 scopus 로고
    • Somatic cell mutagenesis in Drosophila melanogaster in comparison with genetic damage in early germ-cell stages
    • Vogel E.W., Zjilstra J.A. Somatic cell mutagenesis in Drosophila melanogaster in comparison with genetic damage in early germ-cell stages. Mutation Res. 180:1987;189-200.
    • (1987) Mutation Res. , vol.180 , pp. 189-200
    • Vogel, E.W.1    Zjilstra, J.A.2
  • 31
    • 0023751542 scopus 로고
    • Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative or inconclusive result
    • Frei H., Würgler F.E. Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative or inconclusive result. Mutation Res. 203:1988;297-308.
    • (1988) Mutation Res. , vol.203 , pp. 297-308
    • Frei, H.1    Würgler, F.E.2
  • 32
    • 0025105539 scopus 로고
    • Basic principles and evaluation results of assays measuring genotoxic damage in somatic cells of Drosophila
    • M.L. Mendelsohn, R.J. Albertini, (Eds.) Wiley, New York
    • E.W. Vogel, A. Szakmary, Basic principles and evaluation results of assays measuring genotoxic damage in somatic cells of Drosophila, in: M.L. Mendelsohn, R.J. Albertini, (Eds.), Mutation and the Environment, part B, Wiley, New York, 1990, pp. 149-158.
    • (1990) Mutation and the Environment , Issue.PART B , pp. 149-158
    • Vogel, E.W.1    Szakmary, A.2
  • 33
    • 0025288239 scopus 로고
    • Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
    • Beranek D.T. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutation Res. 231:1990;11-30.
    • (1990) Mutation Res. , vol.231 , pp. 11-30
    • Beranek, D.T.1


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