Anorectic action of bombesin requires receptor for corticotropin-releasing factor but not for oxytocin

European Journal of Pharmacology

Volumn 340, Issue 2-3, 1997, Pages 99-109

  Plamondon, Hélène ^a   Merali, Zul ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Anorexia; Central nervous system; Feeding; Grooming; GRP(Gastrin releasing peptide)

Indexed keywords

ALPHA CORTICOTROPIN RELEASING FACTOR (9-41); ARGIPRESTOCIN; BOMBESIN; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR DERIVATIVE; OXYTOCIN; OXYTOCIN ANTAGONIST; OXYTOCIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEEDING BEHAVIOR; FOOD INTAKE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MODULATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; APPETITE DEPRESSANTS; BEHAVIOR, ANIMAL; BOMBESIN; BRAIN; BRAIN CHEMISTRY; EATING; INJECTIONS, INTRAVENTRICULAR; MALE; OXYTOCIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, OXYTOCIN; SATIATION;

EID: 0031565154     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01346-0     Document Type: Article

References (62)

1. Arletti R., Benelli A., Bertolini A. Influence of oxytocin on feeding behavior in the rat. Peptides. 10:1989;89-93.
2. Baile C.A., Della-Fera M.A. Bombesin injected into cerebral ventricles decreases food intake of sheep. Fed. Proc. 40:1981;308. (Abstract).
3. Behan D.P., Grigoriadis D.E., Lovenberg T., Chalmers D., Heinrichs S., Liaw C., De Souza E.B. Neurobiology of corticotropin releasing factor (CRF) receptors and CRF-binding protein: Implications for the treatment of CNS disorders. Mol. Psychiatry. 1:1996;265-277.
4. Brown M., Tache Y., Fisher D. Central nervous system action of bombesin: Mechanism to induce hyperglycemia. Endocrinology. 105(3):1979;660-665.
5. Brown M.R., Fisher L.A. Corticotropin releasing factor: Effects on the autonommic nervous system and visceral systems. Fed. Proc. 44:1985;243-248.
6. Brown M.R., Fisher L.A., Spiess J., Rivier C., Rivier J., Vale W. Corticotropin-releasing factor (CRF): Actions on the sympathetic nervous system and metabolism. Endocrinology. 111:1982;928-931.
7. Brown M.R., Rivier J., Vale W.W. Bombesin affects the central nervous system to produce hyperglycemia in rats. Life Sci. 21:1977;1729-1734.
8. Bruhn T.O., Sutton S.W., Plotsky P.M., Vale W.W. Central administration of corticotropin-releasing factor modulates oxytocin secretion in the rat. Endocrinology. 119:1986;1558-1563.
9. Caldwell J.D., Drago F., Prange A.J., Pederson C.A. Comparison of grooming behavior potencies of neurohypophyseal nonapeptides. Regul. Pept. 14:1986;261-271.
10. Campfield L.A., Smith F.J. Functional coupling between transient declines in blood glucose and feeding behaviour: Temporal relationships. Br. Res. Bull. 17:1986;427-433.
11. Chronwall B.M., Pisano J.J., Bishop J.F., Moody T.W., O'Donohue T.L. Biochemical and histochemical characterization of ranatensin immunoreactive peptides in rat brain: Lack of coexistence with bombesin/GRP. Brain Res. 338:1985;97-113.
12. Cummings S., Elde R., Ells J., Lindall A. Corticotropin-releasing factor immunoreactivity is widely distributed within the central nervous system of the rat: An immunohistochemical study. J. Neurosci. 3:1983;1355-1367.
13. Dunn A.J., File S.E. Corticotropin-releasing factor (CRF) displays an anxiogenic action in the social interaction test. Horm. Behav. 21:1987;193-202.
14. Flynn F.W. Caudal brain stem systems mediate effects of bombesin-like peptides on intake in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 262:1992;R39-R45.
15. Flynn F.W. Fourth ventricular injection of selective bombesin receptor antagonists facilitates feeding in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 264:1993;R218-R221.
16. Gibbs D.M. Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress. Life Sci. 35:1984;487-491.
17. Gibbs J., Kulkosky P.J., Smith G.P. Effects of peripheral and central bombesin on feeding behavior of rats. Peptides. 2:1981;179-183.
18. Gmerek D.E., Cowan A. Studies on bombesin-induced grooming in rats. Peptides. 4:1983;907-913.
19. Gosnell B.A., Morley J.E., Levine A.S. Adrenal modulation of the inhibitory effect of corticotropin releasing factor on feeding. Peptides. 4:1983;807-812.
20. Johnston S.A., Merali Z. Specific neuroanatomical and neurochemical correlates of locomotor and grooming effects of bombesin. Peptides. 9 (Suppl. 1):1988;245-256.
21. Kateb C.C., Merali Z. A single meal elicits regional changes in bombesin-like peptide levels in the gut and brain. Brain Res. 596:1992;10-16.
22. Krahn D.D., Gosnell B.A., Grace M., Levine A.S. CRF antagonist partially reverses CRF- and stress-induced effects on feeding. Br. Res. Bull. 17:1986;285-289.
23. Krahn D.D., Gosnell B.A., Levine S.A., Morley J.E. Behavioral effects of corticotropin-releasing factor: Localization and characterization of central effects. Br. Res. 443:1988;63-69.
24. Kyrkouli S.E., Stanley B.G., Leibowitz S.F. Bombesin-induced anorexia: Sites of action in the rat brain. Peptides. 8(2):1987;237-241.
25. Ladenheim E.E., Ritter R.C. Caudal hindbrain participation in the suppression of feeding by central and peripheral bombesin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 264:1993;R1229-R1234.
26. Lang R.E., Heil J.W.E., Ganten D., Hermann K., Unger T., Rascher W. Oxytocin unlike vasopressin is a stress hormone in the rat. Neuroendocrinology. 37:1983;314-316.
27. Levine A.S., Rogers B., Kneip J., Grace M., Morley J.E. Effect of centrally administered corticotropin releasing factor (CRF) on multiple feeding paradigms. Neuropharmacology. 22:1983;337-339.
28. Lin M.T., Ho L.T., Chan H.K. Effects of oxytocin and (1-penicillamine, 4-threonine)oxytocin on thermoregulation in rats. Neuropharmacology. 22:1983;1007-1013.
29. Menzagui F., Howard R.L., Heinrichs S.C., Vale W., Rivier J., Koob G.F. Characterization of a novel and potent corticotropin-releasing factor antagonist in rats. J. Pharmacol. Exp. Ther. 269:1994;564-572.
30. Merali Z., Banks K. Does the histaminergic system mediate bombesin/GRP-induced suppression of food intake. Am. J. Physiol. Regul. Integr. Comp. Physiol. 267:1994;R1589-R1595.
31. Merali Z., Kateb C.C. Rapid alterations of hypothalamic and hippocampal bombesin-like peptide levels with feeding status. Am. J. Physiol. 265:1993;R420-R425.
32. 12]bombesin: Central versus peripheral effects. Ann. N. Y. Acad. Sci. 547:1988;489-492.
33. Merali Z., Moody T.W., Coy D. Blockade of brain bombesin/GRP receptors increases food intake in satiated rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 264:1993;R1031-R1034.
34. Merali, Z., Plamondon, H., Kent, P., Banks, K., 1994. Corticotropin-releasing factor (CRF) antagonist blocks the autonomic, endocrine, ingestive and behavioral effects of central bombesin (BN). Soc. Neurosci. Abs. 528.1, abstract.
35. Moody T.W., Korman L.Y., O'Donohue T.L. Neuromedin B-like peptides in rat brain: Biochemical characterization, mechanism of release and localization in synaptosomes. Peptides. 7:1986;815-820.
36. Moody T.W., O'Donohue T.L., Jacobowitz D.M. Biochemical localization and characterization of bombesin-like peptides in discrete regions of rat brain. Peptides. 2:1981;75-80.
37. Morley J.E., Levine A.S. Corticotropin-releasing factor, grooming and ingestive behavior. Life Sci. 31:1982;1459-1464.
38. Motamedi F., Rashidy-Pour A., Zarrindast M.R., Badavi M. Bombesin-induced anorexia requires central bombesin receptor activation: Independence from interaction with central catecholaminergic systems. Psychopharmacology. 110:1993;193-197.
39. Mönnikes H., Heymann-Mönnikes I., Tache Y. CRF in the paraventricular nucleus of the hypothalamus induces dose-related behavioral profile in rats. Br. Res. 574:1992;70-76.
40. Muurahainen N.E., Kissileff H.R., Pi-Sunyer F.X. Intravenous infusion of bombesin reduces food intake in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 264:1993;R350-R354.
41. Novin, D., Vanderweele, D.A., Rezek, M., 1973. Hepatic-portal 2-deoxy-D-glucose infusion causes eating: Evidence for peripheral glucoreceptors. Science 858-860.
42. Olsen B.R., Drutarosky M.D., Stricker E.M., Verbalis J.G. Brain oxytocin receptor antagonism blunts the effects of anorexigenic treatments in rats: Evidence for central oxytocin inhibition of food intake. Endocrinology. 129:1991;785-791.
43. Olsen B.R., Drutarosky M.D., Stricker E.M., Verbalis J.G. Brain oxytocin receptors mediate corticotropin-releasing hormone-induced anorexia. Am. J. Physiol. 260:1991;R448-R452.
44. Olson B.R., Drutarosky M.D., Chow M.S., Hruby V.J., Stricker E.M., Verbalis J.G. Oxytocin and oxytocin agonist administered centrally decrease food intake in rats. Peptides. 12:1991;113-118.
45. Panula P., Yang H.Y.T., Costa E. Neuronal location of the bombesin-like immunoreactivity in the central nervous system of the rat. Regul. Pept. 4:1982;275-283.
46. Paxinos, G., Watson, C., 1986. The Brain in Stereotaxic Coordinates. Academic Press, New York.
47. Pederson C.A., Caldwell J.D., Drago F., Noonan L.R., Peterson G., Hood L.E., Prange A.J.J. Grooming behavioral effects of oxytocin. Pharmacology, ontogeny, and comparisons with other nonapeptides. Ann. N. Y. Acad. Sci. 525:1988;245-256.
48. Plamondon H., Merali Z. Push-pull perfusion reveals meal-dependent changes in the release of bombesin-like peptides in the rat paraventricular nucleus. Brain Res. 668:1994;54-61.
49. Plamondon H., Merali Z. Regulation of ingestion by CRF and bombesin-like peptides: Distinct meal-related peptide level changes. Am. J. Physiol. 272:1997;R268-R274.
50. Richard D. Involvement of corticotropin-releasing factor in the control of food intake and energy expenditure. Ann. N. Y. Acad. Sci. 697:1993;155-172.
51. Rivest S., Richard D. Involvement of corticotropin-releasing factor in the anorexia induced by exercise. Br. Res. Bull. 25:1990;169-172.
52. Rivier C., Brownstein M., Spiess J., Rivier J., Vale W. In vivo corticotropin-releasing factor-induced secretion of adrenocorticotropin, β-endorphin and corticosterone. Endocrinology. 110:1982;272-278.
53. Sander L.D., Thomas R.M. Gastrin releasing peptide, but not pentagastrin, stimulates ACTH and cortisol secretion in conscious dogs. Regul. Pept. 35:1991;127-133.
54. Shibasaki T., Yamauchi N., Kato Y., Masuda A., Imaki T., Hotta M., Demura H., Oono H., Ling N., Shizume K. Involvement of corticotropin-releasing factor in restraint stress-induced anorexia and reversion of the anorexia by somatostatin in the rat. Life Sci. 43:1988;1103-1110.
55. Stuckey J.A., Gibbs J. Lateral hypothalamic injection of bombesin decreases food intake in rats. Brain Res. 8:1982;617-621.
56. Stuckey J.A., Gibbs J., Smith G.P. Neural disconnection of gut from brain blocks bombesin-induced satiety. Peptides. 6:1985;1249-1252.
57. Swaab D.F., Pool C.W., Nijveld F. Immunofluorescence of vasopressin and oxytocin in rat hypothalamo-neurohypophysial system. J. Neural Trans. 36:1975;195-215.
58. Swanson L.W., Sawchenko P.E., Rivier J., Vale W.W. Organization of ovine corticotropin-releasing factor (CRF)- immunoreactive cells and fibers in the rat brain: An immunohistochemical study. Neuroendocrinology. 36:1983;165-186.
59. Thomas R.M., Sander L.D. Influence of CCK and bombesin on ACTH and cortisol secretion in the conscious dog. Peptides. 6:1985;703-707.
60. Tribollet E., Barberis C., Jard S., Dubois-Dauphin M., Dreifuss J.J. Localization and pharmacological characteristics of high affinity binding sites for vasopressin and oxytocin in the rat brain by light microscopic autoradiography. Br. Res. 442:1988;105-118.
61. Verbalis J.G., McCann M.J., McHale C.M., Stricker E.M. Oxytocin secretion in response to cholecystokinin and food: Differentiation of nausea from satiety. Science. 232:1986;1417-1419.
62. Verbalis J.G., McCann M.J., Stricker E.M. Species-specific effects of bombesin on gastric emptying and neurohypophyseal secretion. Peptides. 9:1988;1289-1293.