Antigen specificity of CD4 T cell response in the central nervous system of mice infected with mouse hepatitis virus

Virology

Volumn 238, Issue 1, 1997, Pages 68-78

  Xue, Shurong ^a   Perlman, Stanley ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; EPITOPE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CELLULAR IMMUNITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; MOUSE; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS CELL INTERACTION;

ANIMALIA; CORONAVIRUS; MURINAE; MURINE HEPATITIS VIRUS;

EID: 0031564074     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8819     Document Type: Article

References (50)

1. Adami, C., Pooley, J., Glomb, J., Stecker, E., Fazal, F., Fleming, J. O., and Baker, S. C. (1995). Evolution of mouse hepatitis virus (MHV) during chronic infection: Quasispecies nature of the persisting MHV RNA. Virology 209, 337-346.
2. b-restricted CTL response. J. Gen. Virol. 77, 315-325.
3. Buchmeier, M. J., Lewicki, H. A., Talbot, P. J., and Knobler, R. L. (1984). Murine hepatitis virus-4 (strain JHM)-induced neurologic disease is modulated in vivo by monoclonal antibody. Virology 132, 261-270.
4. Castro, R. F., Evans, G. D., Jaszewski, A., and Perlman, S. (1994). Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells. Virology 200, 733-743.
5. Castro, R. F., and Perlman, S. (1995). CD8+ T cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity. J. Virol. 69, 8127-8131.
6. Cheever, F. S., Daniels, J. B., Pappenheimer, A. M., and Bailey, O. T. (1949). A murine virus (JHM) causing disseminated encephalomyelitis with extensive destruction of myelin. J. Exp. Med. 90, 181-194.
7. Compton, S. R., Barthold, S. W., and Smith, A. L. (1993). The cell and molecular pathogenesis of coronaviruses. Lab. Anim. Sci. 43, 15-28.
8. Dalziel, R. G., Lampert, P. W., Talbot, P. J., and Buchmeier, M. J. (1986). Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence. J. Virol. 59, 463-471.
9. Erlich, S., Matsushima, G., and Stohlman, S. (1989). Studies on the mechanism of protection from acute viral encephalomyelitis by delayed-type hypersensitivity inducer T cell clones. J. Neurol. Sci. 90, 203-216.
10. Fleming, J. O., Shubin, R. A., Sussman, M. A., Casteel, N., and Stohlman, S. A. (1989). Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis. Virology 168, 162-167.
11. Gerety, S., Rundell, M. K., Del Canto, M. C., and Miller, S. D. (1994). Class II-restricted T cell response in Theiler's murine encephalomyelitis virus-induced demyelinating disease. J. Immunol. 152, 919-929.
12. + T cells. Microb. Pathog. 18, 211-221.
13. Harty, J. T., and Bevan, M. (1995). Specific immunity to Listeria monocytogenes in the absence of IFN gamma. Immunity 3, 109-117.
14. Haspel, M. V., Lampert, P. W., and Oldstone, M. B. A. (1978). Temperature-sensitive mutants of mouse hepatitis virus produce a high incidence of demyelination. Proc. Natl. Acad. Sci. USA 75, 4033-4036.
15. + cytotoxic T cells is defined by peptide length. Immunology 85, 517-522.
16. + cytotoxic T cells against mouse hepatitis virus A59. Immunology 84, 521-527.
17. Houtman, J. J., and Fleming, J. O. (1996a). Dissociation of demyelination and viral clearance in congenially immunodeficient mice infected with murine coronavirus JHM. J. Neurovirol. 2, 101-110.
18. Houtman, J. J., and Fleming, J. O. (1996b). Pathogenesis of mouse hepatitis virus-induced demyelination. J. Neurovirol. 2, 361-376.
19. Imrich, H., Schwender, S., Hein, A., and Dorries, R. (1994). Cervical lymphoid tissue but not the central nervous system supports proliferation of virus-specific T lymphocytes during coronavirus-induced encephalitis in rats. J. Neuroimmunol. 53, 73-81.
20. Irani, D. N., Lin, K.-I., and Griffin, D. E. (1997). Regulation of brain-derived T cells during acute central nervous system inflammation. J. Immunol. 158, 2318-2326.
21. + T cells. J. Immunol. 147, 2317-2323.
22. Kyuwa, S., and Stohlman, S. A. (1990). Pathogenesis of a neurotropic murine coronavirus, strain JHM in the central nervous system of mice. Semin. Virol. 1, 273-280.
23. Lane, T. E., and Buchmeier, M. J. (1997). Murine coronavirus infection: A paradigm for virus-induced demyelinating disease. Trends Microbiol. 5, 9-14.
24. Lane, T. E., Paoletti, A. D., and Buchmeier, M. J. (1997). Disassociation between the in vitro and in vivo effects of nitric oxide on a neurotropic murine coronavirus. J. Virol. 71, 2202-2210.
25. Lecomte, J., Cainelli-Gebara, V., Mercier, G., Mansour, S., Talbot, P. J., Lussier, G., and Oth, D. (1987). Protection from mouse hepatitis virus type 3-induced acute disease by an anti-nucleoprotein monoclonal antibody. Arch. Virol. 97, 123-130.
26. Luytjes, W., Sturman, L. S., Bredenbeek, P. J., Charite, J., van der Zeijst, B. A. M., Horzinek, M. C., and Spaan, W. J. M. (1987). Primary structure of the glycoprotein E2 of coronavirus MHV-A59 and identification of the trypsin cleavage site. Virology 161, 479-487.
27. Miller, S. D., and Karpus, W. J. (1994). The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol. Today 15, 356-361.
28. + T cell subset that responds to viral glycoproteins. Virology 187, 443-452.
29. Nakanaga, K., Yamanouchi, K., and Fujiwara, K. (1986). Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice. J. Virol. 59, 168-171.
30. Njenga, M. K., Pavelko, K., Baisch, J., Lin, X., David, C., Leibowitz, J. L., and Rodriguez, M. (1996). Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice. J. Virol. 70, 1729-1737.
31. Parker, S. E., Gallagher, T. M., and Buchmeier, M. J. (1989). Sequence analysis reveals extensive polymorphism and evidence of deletions within the E2 glycoprotein gene of several strains of murine hepatitis virus. Virology 173, 664-673.
32. Pearce, B. D., Hobbs, M. V., McGraw, T. S., and Buchmeier, M. J. (1994). Cytokine induction during T-cell-mediated clearance of mouse hepatitis virus from neurons in vivo. J. Virol. 68, 5483-5495.
33. Perlman, S., Jacobsen, G., Olson, A. L., and Afifi, A. (1990). Identification of the spinal cord as a major site of persistence during chronic infection with a murine coronavirus. Virology 175, 418-426.
34. Perlman, S., Schelper, R., Bolger, E., and Ries, D. (1987). Late onset, symptomatic, demyelinating encephalomyelitis in mice infected with MHV-JHM in the presence of maternal antibody. Microbiol. Pathogen. 2, 185-194.
35. Pewe, L., Wu, G., Barnett, E. M., Castro, R., and Perlman, S. (1996). Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. Immunity 5, 253-262.
36. Rudensky, A., Preston-Hulbert, P., Al-Ramadi, B., Rothbard, J., and Janeway, C. A. (1992). Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs. Nature 359, 429-431.
37. Sanger, F., Nicklen, S., and Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
38. Sedgwick, J. D., and Holt, P. G. (1983). A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells. J. Immunol. Methods 57, 301-309.
39. Sinigaglia, F., and Hammer, J. (1994). Rules for peptide binding to MHC class II molecules. APMIS 102, 241-248.
40. Stohlman, S. A., Kyuwa, S., Polo, J. M., Brady, D., Lai, M. M. C., and Bergmann, C. C. (1993). Characterization of mouse hepatitis virus-specific cytotoxic T cells derived from the central nervous system of mice infected with the JHM strain. J. Virol. 67, 7050-7059.
41. Stohlman, S. A., Matsushima, G. K., Casteel, N., and Weiner, L. P. (1986). In vivo effects of coronavirus-specific T cell clones: DTH inducer cells prevent a lethal infection but do not inhibit virus replication. J. Immunol. 136, 3052-3056.
42. Sun, N., Grzybicki, D., Castro, R., Murphy, S., and Perlman, S. (1995). Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus. Virology 213, 482-493.
43. Van der Veen, R. C. (1996). Immunogenicity of JHM virus proteins: Characterization of a CD4+ T cell epitope on nucleocapsid protein which induces different T-helper cell subsets. Virology 225, 339-346.
44. b binding, self-nonself discrimination, and TCR antagonism. J. Immunol. 152, 4526-4536.
45. Wege, H. (1995). Immunopathological aspects of coronavirus infection. Springer Semin. Immunopathol. 17, 133-148.
46. Wege, H., Schliephake, A., Korner, H., Flory, E., and Wege, H. (1993). An immunodominant CD4+ T cell site on the nucleocapsid protein of murine coronavirus contributes to protection against encephalomyelitis. J. Gen. Virol. 74, 1287-1294.
47. Weiner, L. P. (1973). Pathogenesis of demyelination induced by a mouse hepatitis virus (JHM virus). Arch. Neurol. 28, 298-303.
48. + T cells. J. Virol. 64, 4589-4592.
49. + T cell epitope within the M protein of a neurotropic coronavirus. Virology 208, 173-179.
50. Yamaguchi, K., Goto, N., Kyuwa, S., Hayami, M., and Toyoda, Y. (1991). Protection of mice from a lethal coronavirus infection in the central nervous system by adoptive transfer of virus-specific T cell clones. J. Neuroimmunol. 32, 1-9.