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Volumn 236, Issue 1, 1997, Pages 16-28

Inhibition of retinoic acid receptor function in normal human mammary epithelial cells results in increased cellular proliferation and inhibits the formation of a polarized epithelium in vitro

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID; RETINOIC ACID RECEPTOR;

EID: 0031563775     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1997.3694     Document Type: Article
Times cited : (42)

References (56)
  • 1
    • 0026927623 scopus 로고
    • Retinoids, retinoid-responsive genes, cell differentiation, and cancer
    • 1. Gudas, L. J. (1992) Retinoids, retinoid-responsive genes, cell differentiation, and cancer. Cell Growth Differ. 3, 655-662.
    • (1992) Cell Growth Differ. , vol.3 , pp. 655-662
    • Gudas, L.J.1
  • 2
    • 0028079763 scopus 로고
    • Vitamin A, differentiation and cancer
    • 2. Love, J. M., and Gudas, L. J. (1994) Vitamin A, differentiation and cancer. Curr. Opin. Cell Biol. 6, 825-831.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 825-831
    • Love, J.M.1    Gudas, L.J.2
  • 7
    • 0028047150 scopus 로고
    • Prevention of second primary tumors with isotretinoin in patients with squamous cell carcinoma of the head and neck: Long-term follow-up
    • 7. Benner, S. E., Pajak, T. F., Lippman, S. M., and Hong, W. K. (1994) Prevention of second primary tumors with isotretinoin in patients with squamous cell carcinoma of the head and neck: Long-term follow-up. J. Natl. Cancer Inst. 86, 140-141.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 140-141
    • Benner, S.E.1    Pajak, T.F.2    Lippman, S.M.3    Hong, W.K.4
  • 8
    • 0028419153 scopus 로고
    • The retinoid signalling pathway: Molecular and genetic analyses
    • 8. Chambon, P. (1994) The retinoid signalling pathway: Molecular and genetic analyses. Semin. Cell. Biol. 5, 115-125.
    • (1994) Semin. Cell. Biol. , vol.5 , pp. 115-125
    • Chambon, P.1
  • 9
    • 0026483824 scopus 로고
    • Prevention of local relapses and new localizations of oral leukoplakia with the synthetic retinoid fenretinide (4-HPR): Preliminary results
    • 9. Chiesa, F., Tradati, N., Marazza, M., Rossi, N., Boracchi, P., Mariani, L., Clerici, M., Formelli, F., Barzan, L., and Carrassi, A. (1994) Prevention of local relapses and new localizations of oral leukoplakia with the synthetic retinoid fenretinide (4-HPR): Preliminary results. Eur. J. Cancer 28B, 97-102.
    • (1994) Eur. J. Cancer , vol.28 B , pp. 97-102
    • Chiesa, F.1    Tradati, N.2    Marazza, M.3    Rossi, N.4    Boracchi, P.5    Mariani, L.6    Clerici, M.7    Formelli, F.8    Barzan, L.9    Carrassi, A.10
  • 10
    • 0001319804 scopus 로고
    • Retinoids and human cancer
    • (Sporn, M. B., Roberts, A. B., and Goodman, D. S., Eds.), Raven Press, New York
    • 10. Hong, W. K., and Itri, L. M. Retinoids and human cancer. (1994) in The Retinoids: Biology, Chemistry, and Medicine (Sporn, M. B., Roberts, A. B., and Goodman, D. S., Eds.), pp. 597-658, Raven Press, New York.
    • (1994) The Retinoids: Biology, Chemistry, and Medicine , pp. 597-658
    • Hong, W.K.1    Itri, L.M.2
  • 12
    • 0028343678 scopus 로고
    • Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: A randomized trial
    • 12. Meyskens, F. L., Jr., Surwit, E., Moon, T. E., Childers, J. M., Davis, J. R., Dorr, R. T., Johnson, C. S., and Alberts, D. S. (1994) Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: A randomized trial. J. Natl. Cancer Inst. 86, 539-543.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 539-543
    • Meyskens F.L., Jr.1    Surwit, E.2    Moon, T.E.3    Childers, J.M.4    Davis, J.R.5    Dorr, R.T.6    Johnson, C.S.7    Alberts, D.S.8
  • 17
    • 0023520940 scopus 로고
    • Identification of a receptor for the morphogen retinoic acid
    • 17. Giguere, V., Ong, E. S., Segui, P., and Evan, R. M. (1987) Identification of a receptor for the morphogen retinoic acid. Nature 330, 624-629.
    • (1987) Nature , vol.330 , pp. 624-629
    • Giguere, V.1    Ong, E.S.2    Segui, P.3    Evan, R.M.4
  • 18
    • 0023483399 scopus 로고
    • A human retinoic acid receptor which belongs to the family of nuclear receptors
    • 18. Petkovich, M., Brand, N. J., Krust, A., and Chambon, P. (1987) A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature 330, 444-450.
    • (1987) Nature , vol.330 , pp. 444-450
    • Petkovich, M.1    Brand, N.J.2    Krust, A.3    Chambon, P.4
  • 19
    • 0023893729 scopus 로고
    • A new retinoic acid receptor identified from a hepatocellular carcinoma
    • 19. Benbrook, D., Lernhardt, E., and Pfahl, M. (1988) A new retinoic acid receptor identified from a hepatocellular carcinoma. Nature 333, 669-672.
    • (1988) Nature , vol.333 , pp. 669-672
    • Benbrook, D.1    Lernhardt, E.2    Pfahl, M.3
  • 24
    • 0025937940 scopus 로고
    • High frequency of retinoic acid receptor-β abnormalities in human lung cancer
    • 24. Gerbert, J. F., Moghal, N., Frangioni, J. V., Sugarbaker, D. J., and Neel, B. G. (1991) High frequency of retinoic acid receptor-β abnormalities in human lung cancer. Oncogene 6, 1859-1868.
    • (1991) Oncogene , vol.6 , pp. 1859-1868
    • Gerbert, J.F.1    Moghal, N.2    Frangioni, J.V.3    Sugarbaker, D.J.4    Neel, B.G.5
  • 25
    • 0025935419 scopus 로고
    • Implications of the RARβ in epidermoid (squamous) lung cancer
    • 25. Houle, B., Leduc, F., and Bradley, W. E. C. (1991) Implications of the RARβ in epidermoid (squamous) lung cancer. Genes Chromosomes Cancer 3, 358-366.
    • (1991) Genes Chromosomes Cancer , vol.3 , pp. 358-366
    • Houle, B.1    Leduc, F.2    Bradley, W.E.C.3
  • 26
    • 0026394539 scopus 로고
    • Abnormal expression of retinoic acid receptors and keratin 19 by human oral and epidermal squamous cell lines
    • 26. Hu, L., Crowe, D., Rheinwald, J. G., Chambon, P., and Gudas, L. J. (1991) Abnormal expression of retinoic acid receptors and keratin 19 by human oral and epidermal squamous cell lines. Cancer Res. 51, 3972-3981.
    • (1991) Cancer Res. , vol.51 , pp. 3972-3981
    • Hu, L.1    Crowe, D.2    Rheinwald, J.G.3    Chambon, P.4    Gudas, L.J.5
  • 27
    • 0026762673 scopus 로고
    • Expression and regulation of retinoic acid receptors in human breast cancer cells
    • 27. Roman, S. D., Clarke, C. L., Hall, R. E., Alexander, I. E., and Sutherland, R. L. (1992) Expression and regulation of retinoic acid receptors in human breast cancer cells. Cancer Res. 52, 2236-2242.
    • (1992) Cancer Res. , vol.52 , pp. 2236-2242
    • Roman, S.D.1    Clarke, C.L.2    Hall, R.E.3    Alexander, I.E.4    Sutherland, R.L.5
  • 28
    • 0027535564 scopus 로고
    • Tumor-suppressive effect of the retinoic acid receptor-β in human epidermoid lung cancer cells
    • 28. Houle, B., Rochette-Egly, C., and Bradley, W. E. C. (1993) Tumor-suppressive effect of the retinoic acid receptor-β in human epidermoid lung cancer cells. Proc. Natl. Acad. Sci. USA 90, 958-989.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 958-989
    • Houle, B.1    Rochette-Egly, C.2    Bradley, W.E.C.3
  • 30
    • 0028147929 scopus 로고
    • Down-regulation of a retinoic acid receptor-β in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells
    • 30. Swisshelm, K., Ryan, K., Lee, X., Tsou, H. C., Peacocke, M., and Sager, R. (1994) Down-regulation of a retinoic acid receptor-β in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells. Cell Growth Differ. 5, 133-141.
    • (1994) Cell Growth Differ. , vol.5 , pp. 133-141
    • Swisshelm, K.1    Ryan, K.2    Lee, X.3    Tsou, H.C.4    Peacocke, M.5    Sager, R.6
  • 31
    • 0029152178 scopus 로고
    • Expression of retinoic acid receptor β mediates retinoid-induced growth arrest and apoptosis in breast cancer cells
    • 31. Seewaldt, V. L., Johnson, B. S., Parker, M. B., Collins, S. J., and Swisshelm, K. (1995) Expression of retinoic acid receptor β mediates retinoid-induced growth arrest and apoptosis in breast cancer cells. Cell Growth Differ. 6, 1077-1088.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1077-1088
    • Seewaldt, V.L.1    Johnson, B.S.2    Parker, M.B.3    Collins, S.J.4    Swisshelm, K.5
  • 33
    • 0027078742 scopus 로고
    • A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line
    • 33. Tsai, S., Bartelmez, S., Heyman, R., Damm, K., Evans, R., and Collins, S. J. (1992) A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line. Genes Dev. 6, 2258-2269.
    • (1992) Genes Dev. , vol.6 , pp. 2258-2269
    • Tsai, S.1    Bartelmez, S.2    Heyman, R.3    Damm, K.4    Evans, R.5    Collins, S.J.6
  • 34
    • 0027297095 scopus 로고
    • A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocytic stage
    • 34. Tsai, S., and Collins, S. J. (1993) A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocytic stage. Proc. Natl. Acad. Sci. USA 90, 7153-7157.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7153-7157
    • Tsai, S.1    Collins, S.J.2
  • 35
    • 0028004304 scopus 로고
    • Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development
    • 35. Tsai, S., Bartelmez, S., Sitnicka, E., and Collins, S. (1994) Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development. Genes Dev. 8, 2831-2841.
    • (1994) Genes Dev. , vol.8 , pp. 2831-2841
    • Tsai, S.1    Bartelmez, S.2    Sitnicka, E.3    Collins, S.4
  • 36
    • 0028962367 scopus 로고
    • New wrinkles in retinoids
    • 36. Anderson, B., and Rosenfield, M. G. (1995) New wrinkles in retinoids. Nature 374, 118-119.
    • (1995) Nature , vol.374 , pp. 118-119
    • Anderson, B.1    Rosenfield, M.G.2
  • 38
    • 0028941493 scopus 로고
    • Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor
    • 38. Saitou, M., Sugai, S., Tanaka, T., Shimouchi, K., Fuchs, E., Narumiya, S., and Kakizuka, A. (1995) Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor. Nature 374, 159-162.
    • (1995) Nature , vol.374 , pp. 159-162
    • Saitou, M.1    Sugai, S.2    Tanaka, T.3    Shimouchi, K.4    Fuchs, E.5    Narumiya, S.6    Kakizuka, A.7
  • 39
    • 0027526297 scopus 로고
    • Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants
    • 39. Damm, K., Heyman, R. A., Umesono, K., and Evans, R. M. (1993) Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants. Proc. Natl. Acad. Sci. USA 90, 2989-2993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2989-2993
    • Damm, K.1    Heyman, R.A.2    Umesono, K.3    Evans, R.M.4
  • 40
    • 0022388785 scopus 로고
    • Isolation and growth of human mammary epithelial cells
    • 40. Stampfer, M. (1985) Isolation and growth of human mammary epithelial cells. J. Tissue Cult. Methods 9, 107.
    • (1985) J. Tissue Cult. Methods , vol.9 , pp. 107
    • Stampfer, M.1
  • 41
    • 0016426055 scopus 로고
    • A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses
    • 41. Russell, W. C., Newman, C., and Williamson, D. H. (1975) A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature 253, 461-462.
    • (1975) Nature , vol.253 , pp. 461-462
    • Russell, W.C.1    Newman, C.2    Williamson, D.H.3
  • 42
    • 0023583135 scopus 로고
    • Specific expression of the pS2 gene in subclasses of breast cancer in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2
    • 42. Rio, M. C., Bellocq, J. P., Gairard, B., Rasmussen, U. B., Krust, A., Koehl, C., Calderoli, H., Schiff, V., Renaud, R., and Chambon, P. (1987) Specific expression of the pS2 gene in subclasses of breast cancer in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2. Proc. Natl. Acad. Sci. USA 84, 9243-9247.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 9243-9247
    • Rio, M.C.1    Bellocq, J.P.2    Gairard, B.3    Rasmussen, U.B.4    Krust, A.5    Koehl, C.6    Calderoli, H.7    Schiff, V.8    Renaud, R.9    Chambon, P.10
  • 43
    • 0022550295 scopus 로고
    • A cis-acting element within the 5′ leader of a cytomegalovirus beta transcript determines kinetic class
    • 43. Geballe, A., Spate, R., and Mocarski, E. (1986) A cis-acting element within the 5′ leader of a cytomegalovirus beta transcript determines kinetic class. Cell 46, 865-876.
    • (1986) Cell , vol.46 , pp. 865-876
    • Geballe, A.1    Spate, R.2    Mocarski, E.3
  • 44
    • 0018140371 scopus 로고
    • Role of cell shape in growth control
    • 44. Folkman, J., and Moscona, A. (1978) Role of cell shape in growth control. Nature 273, 345-349.
    • (1978) Nature , vol.273 , pp. 345-349
    • Folkman, J.1    Moscona, A.2
  • 45
    • 0025786161 scopus 로고
    • Control of mammary epithelial differentiation: Basement membrane induces tissue-specific gene expression in the absence of cell-cell interactions and morphologic polarity
    • 45. Streuli, C. H., Bailey, N., and Bissell, M. J. (1991) Control of mammary epithelial differentiation: Basement membrane induces tissue-specific gene expression in the absence of cell-cell interactions and morphologic polarity. J. Cell. Biol. 115, 1383-1395.
    • (1991) J. Cell. Biol. , vol.115 , pp. 1383-1395
    • Streuli, C.H.1    Bailey, N.2    Bissell, M.J.3
  • 46
    • 0001166951 scopus 로고
    • A formaldehyde fixative of high osmolarity for use in electron microscopy
    • 46. Karnovsky, M. J. (1965) A formaldehyde fixative of high osmolarity for use in electron microscopy. J. Cell. Biol. 27, 137.
    • (1965) J. Cell. Biol. , vol.27 , pp. 137
    • Karnovsky, M.J.1
  • 47
    • 0026738947 scopus 로고
    • Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells
    • 47. Petersen, O. W., Ronnov-Jessen, L., Hewlett, A. R., and Bissell, M. J. (1992) Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc. Natl. Acad. Sci. USA 89, 9064-9068.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9064-9068
    • Petersen, O.W.1    Ronnov-Jessen, L.2    Hewlett, A.R.3    Bissell, M.J.4
  • 48
    • 0028576840 scopus 로고
    • A novel function for the nm23-H1 gene: Overexpression in human breast cancer carcinoma cells leads to the formation of basement membrane and growth arrest
    • 48. Hewlett, A. R., Petersen, O. W., Steeg, P. S., and Bissell, M. J. (1994) A novel function for the nm23-H1 gene: Overexpression in human breast cancer carcinoma cells leads to the formation of basement membrane and growth arrest. J. Natl. Cancer Inst. 86, 1838-1843.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1838-1843
    • Hewlett, A.R.1    Petersen, O.W.2    Steeg, P.S.3    Bissell, M.J.4
  • 49
    • 0028557342 scopus 로고
    • Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction
    • 49. Roskelly, C. D., Deprez, P. Y., and Bissell, M. J. (1994) Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc. Natl. Acad. Sci. USA 91, 12378-12382.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12378-12382
    • Roskelly, C.D.1    Deprez, P.Y.2    Bissell, M.J.3
  • 50
    • 0028317084 scopus 로고
    • Growth, differentiation and transformation of human mammary epithelial cells in culture
    • (Dickenson, R., and Lippman, M., Eds.), Kluwer, Dordrecht
    • 50. Stampfer, M. R., and Yaswen, P. (1994) Growth, differentiation and transformation of human mammary epithelial cells in culture. in Mammary Tumorigenesis and Malignant Progression (Dickenson, R., and Lippman, M., Eds.), pp. 29-47, Kluwer, Dordrecht.
    • (1994) Mammary Tumorigenesis and Malignant Progression , pp. 29-47
    • Stampfer, M.R.1    Yaswen, P.2
  • 51
    • 0029312252 scopus 로고
    • Involvement of extracellular matrix constituents in breast cancer
    • 51. Lochter, A., and Bissell, M. J. (1995) Involvement of extracellular matrix constituents in breast cancer. Semin. Cancer Biol. 6, 165-173.
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 165-173
    • Lochter, A.1    Bissell, M.J.2
  • 52
    • 0028168007 scopus 로고
    • Genetic analysis of RXR alpha developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis
    • 52. Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., Le Mur, M., Decimo, D., Vonesch, J.-L., Dolle, P., and Chambon, P. (1994) Genetic analysis of RXR alpha developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell 78, 987-1003.
    • (1994) Cell , vol.78 , pp. 987-1003
    • Kastner, P.1    Grondona, J.M.2    Mark, M.3    Gansmuller, A.4    Le Mur, M.5    Decimo, D.6    Vonesch, J.-L.7    Dolle, P.8    Chambon, P.9
  • 55
    • 0029796637 scopus 로고    scopus 로고
    • Clinical applications of retinoids in prevention and treatment of malignancies
    • 55. Lotan, R. (1996) Clinical applications of retinoids in prevention and treatment of malignancies. FASEB J. 10, 1031-1039.
    • (1996) FASEB J. , vol.10 , pp. 1031-1039
    • Lotan, R.1
  • 56
    • 0029044431 scopus 로고
    • Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isotretinoin
    • 56. Lotan, R., Xu, X.-C., Lippman, S. M., Ro, J. Y., Lee, J. S., Lee, J. J., and Hong, W. K. (1995) Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isotretinoin. N. Engl. J. Med. 332, 1405-1410.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1405-1410
    • Lotan, R.1    Xu, X.-C.2    Lippman, S.M.3    Ro, J.Y.4    Lee, J.S.5    Lee, J.J.6    Hong, W.K.7


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