An acetal derivative of illudin S with improved antitumor activity

Tetrahedron Letters

Volumn 38, Issue 10, 1997, Pages 1697-1698

  McMorris, Trevor C ^a   Yu, Jian ^a   Gantzel, Peter K ^a   Estes, Leita A ^b   Kelner, Michael J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAL DERIVATIVE; ILLUDIN S; MITOMYCIN C; TERPENOID;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL STRAIN HL 60; CHEMICAL MODIFICATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; X RAY CRYSTALLOGRAPHY;

ANIMALIA;

EID: 0031562438     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00196-2     Document Type: Article

References (7)

1. 1. McMorris, T.C.; Anchel, M. J. Am. Chem. Soc. 1965, 87, 1594-1600.
2. 2. McMorris, T.C.; Kelner, M.J.; Wang, W.; Diaz, M.A.; Estes, L.A.; Taetle, R. Experientia 1996, 52, 75-80.
3. 3. Kelner, M.J.; McMorris, T.C.; Estes, L.A.; Montoya, M.A.; Starr, R.; Samson, K.; Taetle, R. Cancer Res. 1995, 55, 4936-4940.
4. 4. McMorris, T.C.; Kelner, M.J.; Wang, W.; Yu, J.; Estes, L.A.; Taetle, R. J. of Nat. Products 1996, 59, 896-899.
5. 5. Kelner, M.J.; McMorris, T.C.; Estes, L.A.; Wang, W.; Samson, K.M.; Taetle, R. Invest. New Drugs 1996, 14, 161-167.
6. 4 calcd 276.1362, found 276.1364; UV λmax 305 nm (ε 3148).
7. 7. Kelner, M.J.; McMorris, T.C.; Taetle, R. Anticancer Res., 1995, 15, 873-878.