Controlled reduction of tertiary amides to the corresponding aldehydes or amines using dialkylboranes

Tetrahedron Letters

Volumn 38, Issue 10, 1997, Pages 1717-1720

  Godjoian, Gayane ^a   Singaram, Bakthan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DERIVATIVE; AMIDE; BORANE DERIVATIVE; ORGANOMETALLIC COMPOUND;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; REDUCTION; STOICHIOMETRY;

EID: 0031562437     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00179-2     Document Type: Article

References (29)

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27. 2), the organic layer was seperated from the aqueous layer, washed with distilled water, and dried over anhydrous magnesium sulfate. GC analysis showed that the 9-BBN reduction of N-pyrrolidinocyclohexanecarboxamide gave 82% of the corresponding amine.
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29. 2), the organic layer was seperated from the aqueous layer, washed with distilled water, and dried over anhydrous magnesium sulfate. GC analysis showed that disiamylborane reduced N,N-diethylbenzamide to benzaldehyde in 99% yield.