Chemoselective addition of Grignard reagents to alkoxycarbonylalkyl-N-imidazolium-N-methyl amides: Synthesis of 4-oxo and homologous esters

Tetrahedron Letters

Volumn 38, Issue 10, 1997, Pages 1817-1820

  De Las Heras, María A ^a   Vaquero, Juan J ^a   García Navio, José L ^a   Alvarez Builla, Julio ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; ESTER; REAGENT;

ACYLATION; ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 0031562386     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00159-7     Document Type: Article

References (18)

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13. 5. Heras, M. A.; Molina, A.; Vaquero, J. J.; García-Navio, J. L.; Alvarez-Builla, J. J. Org. Chem. 1993, 58, 5862.
14. 6. Heras, M. A.; Vaquero, J. J.; García-Navio, J. L.; Alvarez-Builla, J. Tetrahedron, 1996, 52, 14297.
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17. 2O extensive deuteration of the C-2 imidazolium position occurred.
18. 3: C, 34.01; H, 4.57; N, 11.90. Found: C, 33.80; H, 4.84; N, 11.77.