Ultrastructural studies of an immune-mediated inflammatory response in the CNS parenchyma directed against a non-CNS antigen

Neuroscience

Volumn 78, Issue 2, 1997, Pages 549-560

  Matyszak, M K ^a   Townsend, M J ^a   Perry, V H ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

BCG; demyelination; dendrite cell; DTH; inflammation; macrophage

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; DEMYELINATION; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGE; MALE; MICROGLIA; MULTIPLE SCLEROSIS; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; HYPERSENSITIVITY, DELAYED; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MICROSCOPY, ELECTRON; MYCOBACTERIUM BOVIS; RATS; RATS, INBRED LEW; T-LYMPHOCYTES;

EID: 0031562360     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00578-7     Document Type: Article

References (44)

1. 1. Adams C. W. (1989) A Colour Atlas of Multiple Sclerosis and Other Myelin Disorders. Wolfe Medical, London.
2. 2. Ben Nun A., Wekerle H. and Cohen I. R. (1981) The rapid isolation of clonable antigen specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur. J. Immun. 11, 195-199.
3. 3. Bolam J. P. (ed.) (1992) Preparation of central nervous system tissue for light and electron microscopy. In Experimental Neuroanatomy, pp. 1-29. Oxford University Press, Oxford.
4. 4. Brosnan C. F., Stoner G. L., Bloom B. R. and Wisniewsky H. M. (1977) Studies on demyelination by activated lymphocytes in the rabbit eye. II. Antibody-dependent cell-mediated demyelination. J. Immun. 118, 2103-2110.
5. 5. Butt A. M. and Jenkins H. G. (1994) Morphological changes in oligodendrocytes in the intact mouse optic nerve following intravitreal injection of tumour necrosis factor. J. Neuroimmun. 51, 27-33.
6. 6. Calder V., Owen S., Watson C., Feldmann M. and Davison A. (1989) MS: a localized immune disease of the central nervous system. Immun. Today 10, 99-103.
7. 7. Dallman M. J., Mason D. W. and Webb M. (1982) The roles of host and donor cells in the rejection of skin allografts by T cell-deprived rats injected with syngeneic T cells. Eur. J. Immun. 12, 511-518.
8. 8. Gearing A. J. H., Beckett P., Christodoulou M., Churchill M., Clements J., Davidson A. H., Drummond A. H., Galloway W. A., Gilbert R., Gordon J. L., Leber T. M., Mangan M., Miller K., Nayee P., Owen K., Patel S., Thomas W., Wells G., Wood L. M. and Woolley K. (1994) Processing of tumour necrosis factor-α precursor by metallo-proteinases. Nature 370, 555-557.
9. 9. George R. and Griffin J. W. (1994) The proximo-distal spread of axonal degeneration in the dorsal columns of the rat. J. Neurocytol. 23, 657-667.
10. 10. Gijbels K., Proost P., Masure S., Carton H., Billiau A. and Opdenakker G. (1993) Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein. J. Neurosci. Res. 36, 432-440.
11. 11. Goban Y., Saida T., Saida K., Nishitani H. and Kameyama M. (1986) Role of nonspecific myelin destruction by delayed type hypersensitivity in primary demyelination. J. neurol. Sci. 74, 97-109.
12. 12. Goban Y., Saida T., Saida K., Nishitani H. and Kameyama M. (1986) Ultrastructural study of central nervous system demyelination in galactocerebroside sensitized rabbits. Lab. Invest. 55, 86-90.
13. 13. Hart D. J. and Fabre J. W. (1981) Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues but not brain. J. exp. Med. 153, 347-361.
14. 14. Head J. R. and Griffin W. S. (1985) Functional capacity of solid tissue transplants in the brain: evidence for immunological privilege. Proc. R. Soc. Lond. B, Biol. Sci. 224, 375-387.
15. 15. Hickey W. F., Hsu B. L. and Kimura H. (1991) T-lymphocyte entry into the central nervous system. J. Neurosci. Res. 28, 254-260.
16. 16. Hickey W. F. and Kimura H. (1988) Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239, 290-292.
17. 17. Ingham C. A. (1992) Immunocytochemistry. II. Post-embedding staining. In Experimental Neuroanatomy (ed. Bolam J. P.), pp. 129-151. Oxford University Press, Oxford.
18. 18. Kerrison J. B., Flynn T. and Green W. R. (1994) Retinal pathologic changes in multiple sclerosis. Retina 14, 445-451.
19. 19. Lassmann H. (1983) Comparative Neuropathology of Chronic EAE and MS. Springer, Berlin.
20. 20. Lassmann H., Suchanek G. and Ozawa K. (1994) Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis. Ann. Neurol. 36, 542-546.
21. 21. Linington C., Engelhardt B., Kapocs G. and Lassman H. (1992) Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody. J. Neuroimmun. 40, 219-224.
22. 22. Linington C. and Lassmann H. (1987) Antibody responses in chronic relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titre to the myelin/oligodendrocyte glycoprotein (MOG). J. Neuroimmun. 17, 61-69.
23. 23. Low W. C., Lewis P. R. and Terri S. T. (1983) Embryonic neural transplants across a major histocompatibility barrier: survival and specificity of innervation. Brain Res. 262, 328-333.
24. 24. Ludwin S. K. and Johnson E. S. (1981) Evidence for a "dying-back" gliopathy in demyelinating disease. Ann. Neurol. 9, 301-305.
25. 25. Matyszak M. K., Lawson L. J., Perry V. H. and Gordon S. (1992) Stromal macrophages of the choroid plexus situated at an interface between the brain and peripheral immune system constitutively express major histocompatibility class II antigens. J. Neuroimmun. 40, 173-181.
26. 26. Matyszak M. K. and Perry V. H. (1995) Demyelination in the central nervous system following a delayed-type hypersensitivity response to bacillus Calmette-Guérin. Neuroscience 64, 967-977.
27. 27. Matyszak M. K. and Perry V. H. (1996) A comparison of leucocyte responses to heat-killed bacillus Calmette-Guérin in different CNS compartments. Neuropath. appl. Neurobiol. 22, 44-53.
28. 28. Matyszak M. K. and Perry V. H. (1996) The potential role of dendritic cells in immune mediated inflammatory responses in the central nervous system. Neuroscience 74, 599-608.
29. 29. Matyszak M. K. and Perry V. H. (1996) Inflammation induced breakdown of the blood-brain barrier and demyelination are prevented by inhibitors of matrix metalloproteinases. J. Neuroimmun. 69, 141-149.
30. 30. McCall M. N., Shotton D. M. and Barclay A. N. (1992) Expression of soluble isoforms of rat CD45. Analysis by electron microscopy and use in epitope mapping of anti-CD45R monoclonal antibodies. Immunology 76, 310-317.
31. 31. Moll H., Fuchs H., Blank C. and Rollinghoff M. (1993) Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells. Eur. J. Immun. 23, 1595-1601.
32. 32. Notterpek L. M. and Rome L. H. (1994) A protein involved in central nervous system myelination: localization in the extracellular matrix and induction in neuroblastoma cells. Devl Neurosci. 16, 267-278.
33. 33. Pender M. P., Stanley G. P., Yoong G. and Nguyen K. B. (1990) The neuropathology of chronic relapsing experimental allergic encephalomyelitis induced in the Lewis rat by inoculation with whole spinal cord and treatment with cyclosporin A. Acta neuropath. 80, 172-183.
34. 34. Powell H. C., Branheny S. L., Hughes R. A. and Lampert P. W. (1984) Antigen-specific demyelination and significance of bystander effect in peripheral nerves. Am. J. Path. 114, 443-453.
35. 35. Powell H. C. and Hughes R. A. (1987) Demyelination in association with delayed type hypersensitivity. J. neurol. Sci. 78, 357-360.
36. 36. Prineas J. W., Kwon E. E., Cho E.-S. and Sharer L. R. (1984) Continual breakdown and regeneration of myelin in progressive multiple sclerosis plaques. Ann. N. Y. Acad. Sci. 436, 11-32.
37. 37. Robbins D. S., Shirazi Y., Drysdale B. E., Lieberman A., Shin H. S. and Shin M. L. (1987) Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes. J. Immun. 139, 2593-2597.
38. 38. Scolding N. J., Morgan B. P., Houston W. A. J., Linington C., Campbell A. K. and Compston D. A. S. (1989) Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement. Nature 339, 620-622.
39. 39. Selmaj K. W. and Raine C. S. (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann. Neurol. 23, 339-346.
40. 40. Steinman R. M. and Nussenzweig M. C. (1980) Dendritic cells: features and functions. Immun. Rev. 53, 127-147.
41. 41. Viale G., Gambacorta M., Coggi G., Dell'Orto P., Milani M. and Doglioni C. (1991) Glia fibrillary acidic protein immunoreactivity in normal and diseased human breast. Virch. Arch. A. Path. Anat. 418, 339-348.
42. 42. Wekerle H., Sun D., Oropeza W.-R. L. and Meyermann R. (1987) Immune reactivity in the nervous system: modulation of T-lymphocyte activation by glial cells. J. exp. Biol. 132, 43-57.
43. 43. Wiley E. L., Mulhollan T. J., Beck B., Tyndall J. A. and Freeman R. G. (1990) Polyclonal antibodies raised against Bacillus Calmette-Guerin, Mycobacterium duvalii, and Mycobacterium paratuberculosis used to detect mycobacteria in tissue with the use of immunohistochemical techniques. Am. J. clin. Path. 94, 307-312.
44. 44. Wisniewski H. M. and Bloom B. R. (1975) Primary demyelination as a nonspecific consequence of a cell-mediated immune reaction. J. exp. Med. 141, 346-359.