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0011492097
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Katritzky, A. R.; Rees, C. W.; Potts, K. T.; Eds., Pergamon Press: Oxford
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10 Begtrup, M. J. Chem. Soc., Perkin Trans. 2 1976, 736. Janzen, A. F.; Lypka, G. N.; Wasylishen, R. E. Can. J. Chem. 1980, 58, 60.
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10 Begtrup, M. J. Chem. Soc., Perkin Trans. 2 1976, 736. Janzen, A. F.; Lypka, G. N.; Wasylishen, R. E. Can. J. Chem. 1980, 58, 60.
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84943408843
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11 For general reviews upon imidazole synthesis and reactivity see: Grimmett, M. R. in Comprehensive Heterocyclic Chemistry; Katritzky, A. R.; Rees, C. W.; Potts, K. T.; Eds., Pergamon Press: Oxford, 1984; vol. 5, p. 457. Grimmett, M. R. in Adv. Heterocycl. Chem. 1980, 27, 241.
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Grimmett, M.R.1
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77957079603
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11 For general reviews upon imidazole synthesis and reactivity see: Grimmett, M. R. in Comprehensive Heterocyclic Chemistry; Katritzky, A. R.; Rees, C. W.; Potts, K. T.; Eds., Pergamon Press: Oxford, 1984; vol. 5, p. 457. Grimmett, M. R. in Adv. Heterocycl. Chem. 1980, 27, 241.
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Grimmett, M.R.1
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25
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0011390402
-
-
note
-
12 Traces of p-toluenesulfonamide were found when the process leading to imidazole 5 was less efficient (entries 18, 25, 27).
-
-
-
-
26
-
-
0011390302
-
-
note
-
13 Experiments in DMSO were also carried out but, after aqueous quenching of the reaction and extraction with ether (see experimental), the evaporation to dryness of the aqueous/DMSO phase presented some practical difficulties. DMF was thus preferred as reaction solvent because of an easier work-up of the aqueous/DMF phase.
-
-
-
-
27
-
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0000113304
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14 Van Leusen, A. M.; Wildeman, J.; Oldenziel, O. H. J. Org. Chem. 1977, 42, 1153.
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28
-
-
0011436765
-
-
note
-
15 No attempt either to identify or to quantify cyanide anion was done.
-
-
-
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29
-
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0011483006
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16 Nohira, H.; Sato, K.; Mukaiyama, T. Bull. Chem. Soc. Jpn. 1963, 36, 870. Ehrlich, P.; Sachs, F. Chem. Ber. 1899, 32, 2344.
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0011390796
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16 Nohira, H.; Sato, K.; Mukaiyama, T. Bull. Chem. Soc. Jpn. 1963, 36, 870. Ehrlich, P.; Sachs, F. Chem. Ber. 1899, 32, 2344.
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17 Hoppe, D. Angew. Chem., Int. Ed. Engl. 1974, 13, 789. Schöllkopf, U. Angew. Chem., Int. Ed. Engl. 1977, 16, 339. Van Leusen, A. M.; Schaart, F. J.; van Leusen, D. Recl. Trav. Chim. Pays-Bas 1979, 98, 258.
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33748903783
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17 Hoppe, D. Angew. Chem., Int. Ed. Engl. 1974, 13, 789. Schöllkopf, U. Angew. Chem., Int. Ed. Engl. 1977, 16, 339. Van Leusen, A. M.; Schaart, F. J.; van Leusen, D. Recl. Trav. Chim. Pays-Bas 1979, 98, 258.
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84984016718
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17 Hoppe, D. Angew. Chem., Int. Ed. Engl. 1974, 13, 789. Schöllkopf, U. Angew. Chem., Int. Ed. Engl. 1977, 16, 339. Van Leusen, A. M.; Schaart, F. J.; van Leusen, D. Recl. Trav. Chim. Pays-Bas 1979, 98, 258.
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34
-
-
0011485721
-
-
note
-
1H-NMR absorptions tentatively assigned to 4,5-imidazoline ring protons: δ 7.59 (1H, d, J 1.9 Hz, H-2), 4.87 (1H, d, J 6.9 Hz, H-5) and 4.74 (1H, dd, J 1.9 and 6.9 Hz, H-4).
-
-
-
-
36
-
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0011392312
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(b) Ahern, M. F.; Leopold, A.; Beadle, J. R.; Gokel, G. W. J. Amer. Chem. Soc. 1982, 104, 548.
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37
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0011390797
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20 Kojima, M.; Minato, H.; Kobayashi, M. Bull. Chem. Soc. Jpn. 1972, 45, 2032.
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38
-
-
0011443244
-
-
note
-
21b but physical and spectroscopic data are not reported.
-
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39
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0000083067
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(b) Evers, M. J.; Christiaens, L. E.; Renson, M. J., J. Org. Chem. 1986, 51, 5196.
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23 Kamigata, N.; Satoh, A.; Yoshida, M.; Kameyama, M. Bull. Chem. Soc. Jpn. 1989, 62, 606.
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42
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84981566046
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24 Van Nispen, S. P. J. M.; Bregman, J. H.; van Engen, D. G.; van Leusen, A. M.; Saikachi, H.; Kitagawa, T.; Sasaki, H. Recl. Trav. Chim. Pays-Bas 1982, 101, 28.
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Van Nispen, S.P.J.M.1
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Van Leusen, A.M.4
Saikachi, H.5
Kitagawa, T.6
Sasaki, H.7
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