-
1
-
-
0027971096
-
-
1. Horton, P. A.; Koehn, F. E.; Longley, R. E.; McConnell, O. J. J. Am. Chem. Soc. 1994, 116, 6015.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 6015
-
-
Horton, P.A.1
Koehn, F.E.2
Longley, R.E.3
McConnell, O.J.4
-
3
-
-
0001762573
-
-
b) Shirai, R.; Tanaka, M.; Koga, K. J. Am. Chem. Soc. 1986, 108, 543.
-
(1986)
J. Am. Chem. Soc.
, vol.108
, pp. 543
-
-
Shirai, R.1
Tanaka, M.2
Koga, K.3
-
9
-
-
0030574042
-
-
h) Sugasawa, K., Shindo, M.; Noguchi, H.; Koga, K. Tetrahedron Lett. 1996, 37, 7377. Catalytic asymmetric alkylation. See: Imai, M.; Hagihara, H.; Kawasaki, H.; Manabe, K.; Koga, K. J. Am. Chem. Soc. 1994, 116, 8829.
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 7377
-
-
Sugasawa, K.1
Shindo, M.2
Noguchi, H.3
Koga, K.4
-
10
-
-
0001266486
-
-
h) Sugasawa, K., Shindo, M.; Noguchi, H.; Koga, K. Tetrahedron Lett. 1996, 37, 7377. Catalytic asymmetric alkylation. See: Imai, M.; Hagihara, H.; Kawasaki, H.; Manabe, K.; Koga, K. J. Am. Chem. Soc. 1994, 116, 8829.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 8829
-
-
Imai, M.H.H.1
Kawasaki, H.2
Manabe, K.3
Koga, K.4
-
13
-
-
37049071721
-
-
and ref, 2d
-
b) Bunn, B. J.; Simpkins, N. S.; Spavold, Z.; Crimmin, M. J. J. Chem. Soc. Perkin Trans. 1 1993, 3113 and ref, 2d).
-
(1993)
J. Chem. Soc. Perkin Trans. 1
, pp. 3113
-
-
Bunn, B.J.1
Simpkins, N.S.2
Spavold, Z.3
Crimmin, M.J.4
-
15
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-
0011288384
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-
No attempts to recycle the α-configurated alcohol 4-α, e. g. by back oxidation to ketone 3 or by Mitsunobu inversion were made at this stage
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6. No attempts to recycle the α-configurated alcohol 4-α, e. g. by back oxidation to ketone 3 or by Mitsunobu inversion were made at this stage.
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-
-
-
16
-
-
0000449913
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-
7. Martin, S.F. Tetrahedron 1980, 36, 419; Fuji, K. Chem. Rev. 1993, 93, 2037.
-
(1980)
Tetrahedron
, vol.36
, pp. 419
-
-
Martin, S.F.1
-
17
-
-
0001521888
-
-
7. Martin, S.F. Tetrahedron 1980, 36, 419; Fuji, K. Chem. Rev. 1993, 93, 2037.
-
(1993)
Chem. Rev.
, vol.93
, pp. 2037
-
-
Fuji, K.1
-
18
-
-
0001399971
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-
and references cited therein
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8 Currently, four steps and even more per stereogenic centre are not uncommon in total synthesis of complex marine natural products. See: Norcross, R. D.; Paterson, J. Chem. Rev. 1995, 95, 2041 and references cited therein.
-
(1995)
Chem. Rev.
, vol.95
, pp. 2041
-
-
Norcross, R.D.1
Paterson, J.2
-
20
-
-
85047673542
-
-
b) Majewski, M.; Lazny, R.; Nowak, P. Tetrahedron Lett. 1995, 31, 5465.
-
(1995)
Tetrahedron Lett.
, vol.31
, pp. 5465
-
-
Majewski, M.1
Lazny, R.2
Nowak, P.3
-
21
-
-
0028362496
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-
Previously, 8-oxabicyclo[3.2.1]octan-3-one, which is obtained from 1 by catalytic hydrogenation and is more stable, was desymmetrized with a chiral lithium amide base (ca, 78%, 82% e.e.; see ref. 2g)
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c) Majewski, M.; Lazny, R. Tetrahedron Lett. 1994, 35, 3653. Previously, 8-oxabicyclo[3.2.1]octan-3-one, which is obtained from 1 by catalytic hydrogenation and is more stable, was desymmetrized with a chiral lithium amide base (ca, 78%, 82% e.e.; see ref. 2g).
-
(1994)
Tetrahedron Lett.
, vol.35
, pp. 3653
-
-
Majewski, M.1
Lazny, R.2
-
22
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0029118911
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Moreover, the classical problem of polyalkylation is circumvented with methyl cyanoformate
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3-hybridized electrophiles such as methyl halides and also benzyl halides give a poor yield of C-atkytation, which generally does not exceed 35-40%; cf. Rubinger, M. M. M.; Mann, J.; Drew, M. G. B. Tetrahedron 1995, 51, 11295. Moreover, the classical problem of polyalkylation is circumvented with methyl cyanoformate.
-
(1995)
Tetrahedron
, vol.51
, pp. 11295
-
-
Rubinger, M.M.M.1
Mann, J.2
Drew, M.G.B.3
-
25
-
-
33947480171
-
-
12. Overberger, C. G.; Marullo, N. P.; Hiskey, R. G. J. Am. Chem. Soc. 1961, 83, 1374.
-
(1961)
J. Am. Chem. Soc.
, vol.83
, pp. 1374
-
-
Overberger, C.G.1
Marullo, N.P.2
Hiskey, R.G.3
-
26
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0011378203
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note
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+, 11), 164 (21), 151 (23), 140 (25), 124 (20), 108 (24), 101 (61), 95 (12), 82 (100), 69 (66).
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