Synthesis of the spore photoproduct

Tetrahedron Letters

Volumn 38, Issue 6, 1997, Pages 935-936

  Nicewonger, Robb ^a   Begley, Tadhg P ^a  

^a Department of Molecular Biology and Genetics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PYRIMIDINE DERIVATIVE;

ARTICLE; BACTERIAL SPORE; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTOCHEMISTRY; REACTION ANALYSIS;

EID: 0031562057     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02517-8     Document Type: Article

References (16)

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3. c. Cadet, J.; Vigny, P. Bioorganic Photochemistry Morrison, H., Ed., John Wiley & Sons: New York, 1990, Vol. 1, p. 1-273.
4. d. Harm, H. Photochemistry and Photobiology of Nucleic Acids Wang, S. Y., Ed., 1976, Vol. 2, p. 219.
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9. 6. Kinsland, C.; Costello, C.A.; Nicholson, W. L.; Begley, T. P., unpublished results.
10. 7. Zeng, Z.; Zimmerman, S.C. Tetrahedron Lett. 1988, 29, 5123.
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12. -0.02 (18H, m)
13. 10. Wasserman, H. H.; Lipshutz, B. H. Tetrahedron Lett. 1975, 21, 1731.
14. 11. Partial purification of 7 was accomplished by filtering through a short plug of silica using 5% ethyl acetate in methylene chloride as the eluent. Since 7 is unstable, it was used immediately following work up.
15. 3) ppm: 7.32 (2H, d, J=8Hz), 7.22 (2H, d, J=8Hz), 7.00 (1H, s), 6.84 (2H, d, J=8Hz), 6.81 (2H, d, J=8Hz), 5.35 (2H, s), 5.03 (1H, d, J=10Hz), 4.87 (2H, dd, J=14Hz, 24Hz), 4.79 (1H, d, J=14Hz), 4.77 (1H, d, J=10Hz), 4.24 (1H, d, J=14Hz), 3.79 (3H, s), 3.78 (3H, s), 3.64 (2H, dd, J=8Hz, 8Hz), 3.56 (2H, dd, J=8Hz, 8Hz), 3.15 (1H, d, J=13 Hz), 3.03 (1H, d, J=13Hz), 2.61 (1H, d, J=14Hz), 2.54 (1H, d, J=14Hz), 1.03 (3H, s), 0.95-0.90 (4H, m), 0.00 (9H, 2s), -0.02 (9H, 2s).
16. 13. Yoshimura, J.; Yamaura, M.; Suzuki, T.; and Hashimoto, H. Chem. Lett. 1983, 1001.