Randomised trial of magnesium in in-hospital cardiac arrest

Lancet

Volumn 350, Issue 9087, 1997, Pages 1272-1276

  Thel, Mark C ^a   Armstrong, Ann Louise ^a   McNulty, Steven E ^a   Califf, Robert M ^a   O'Connor, Christopher M ^a,b  

^a DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; BLOOD PRESSURE MEASUREMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DOUBLE BLIND PROCEDURE; FEMALE; HEART ARREST; HOSPITAL CARE; HUMAN; INTENSIVE CARE; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PULSE RATE; RANDOMIZED CONTROLLED TRIAL; RESUSCITATION; SURVIVAL; WARD;

EID: 0031560173     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(97)05048-4     Document Type: Article

References (32)

1. Kouwenhoven WB, Jude JR, Knickerbocker CG. Closed-chest cardiac massage. JAMA 1960; 173: 1064-67.
2. Eisenberg MS, Cummins RO, Larsen MP. Numerators, denominators, and survival rates: reporting survival from out-of-hospital cardiac arrest. Am J Emerg Med 1991; 9: 544-46.
3. Callaham M, Madsen CD, Barton CW, Saunders CE, Pointer J. A randomized clinical trial of high-dose epinephrine and norepinephrine vs standard-dose epinephrine in prehospital cardiac arrest. JAMA 1992; 268: 2667-72.
4. Saklayen M, Liss H, Markert R. In-hospital cardiopulmonary resuscitation: survival; in 1 hospital and literature review. Medicine (Baltimore) 1995; 74: 163-75.
5. Sack JB, Kesselbrenner MD, Jarrad A. Interposed abdominal compression-cardiopulmonary resuscitation and resuscitation outcome during asystole and electromechanical dissociation. Circulation 1992; 86: 1692-700.
6. Stiell IG, Hebert PC, Wells GA, et al. The Ontario trial of active compression-decompression cardiopulmonary resuscitation for in-hospital and prehospital cardiac arrest. JAMA 1996; 275: 1417-23.
7. Stiell IG, Wells GA, Hebert PC, Laupacis A, Weitzman BN. Association of drug therapy with survival in cardiac arrest: limited role of advanced cardiac life support drugs. Acad Emerg Med 1995; 2: 264-73.
8. Woods KL. Possible pharmacological actions of magnersium in acute myocardial infarction. Br J Clin Pharmacol 1991; 32: 3-10.
9. Thel MC, O'Connor CM. Magnesium in acute myocardial infarction Coron Artery Dis 1995; 6: 831-37.
10. Woods KL, Fletcher S, Roffe C, Haider Y. Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2). Lancet 1992; 339: 1553-58.
11. Horner SM, Efficacy of intravenous magnesium in acute myocardial infarction in reducing arrhythmias and mortality: meta-analysis of magnesium in acute myocardial infarction. Circulation 1992; 86: 774-79.
12. Teo KK, Yusuf S, Collins R, Held PH, Peto R. Effects of intravenous magnesium in suspected acute myocardial infarction: overview of randomised trials. BMJ 1991; 303: 1499-503.
13. Gettes LS. Electrolyte abnormalities underlying lethal and ventricular arrhythmias. Circulation 1992; 85 (suppl): 170-65.
14. Emergency Cardiac Care Committee and Subcommittees AHA. Guidelines for cardiopulmonary resuscitation and emergency cardiac care - part III: adult advanced cardiac life support. JAMA 1992; 268: 2171-302.
15. Cummins RO, Chamberlain D, Hazinski MF, et al. Recommended guidelines for reviewing, reporting, and conducting research on in-hospital resuscitation: the in-hospital 'Utstein Style'. A statement for healthcare professionals from the american Heart Association, the European Resuscitation Council, the heart and Stroke Foundation of Canada, the Australian Resusciation Council, and the Resuscitation Councils of Southern Africa. Circulation 1997; 95: 2213-39.
16. Department of health and Human Services Food and Drug Administration. Protection of human subjects: informed consent. Federal Register 1995; 60: 49086-103.
17. Teasdale G, Jennett B. Assessment of coma and impaired consciousness: a practical scale. Lancet 1974; ii: 81-84.
18. Karnofsky DA, Borchenal JH. The clinical evaluation of chemotherapeutic agents in cancer. In: Macleod CM, ed. Evaluation of chemotherapeutic agents. New York: Columbia University Press, 1949: 199-205.
19. Thel MC O'Connor CM, Keeler GP, Mark DB. The high costs of in-hospital cardiopulmonary resuscitation. J Am Coll Cardiol 1993; 21: 104A (abstr).
20. Casag rande JT, Pike MC. An improved approximate formula for calculating sample sizes for comparing two binomial distributions. Biometrics 1978; 34: 482-86.
21. Schneider Apd, Nelson DJ, Brown DD. In-hospital cardiopulmonary resuscitation: a 30-year review. J Am Board Fam Pract 1993; 6: 91-101.
22. Sueta CA, Clarke SW, Dunlap SH, et al. Effect of acute magnesium administration on the frequency of ventricular arrhythmia in patients with heart failure. Circulation 1994; 89: 660-66.
23. Hilton TC, Fredman C, Holt DJ, Bjerregaard P, Ira GH, Jr, Janosik DL. Electrophysiologic and antiarrhythmic effects of magnesium in patients with inducible ventricular tachyarrhythmia. Clin Cardiol 1992; 15: 176-80.
24. Roffe C, Fletcher S, Woods KL. Investigation of the effects of intravenous magnesium sulphate on cardiac rhythm in acute myocardial infarction. Br Heart J 1994; 71: 141-45.
25. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group. ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction. Lancet 1995; 345: 669-85.
26. Miller B, Craddock L, Hoffenberg S, et al. Pilot study of intravenous magnesium sulfate in refractory cardiac arrest: safety data and recommendations for future studies. Resuscitation 1995; 30: 3-14.
27. Caspi J, Rudis E, Bar I, Safadi T, Saute M. Effects of magnesium on myocardial function after coronary artery bypass grafting. Ann Thorac Surg 1995; 59: 942-47.
28. Karmy-Jones R, Hamilton A, Dzavik V, Allegreto M, Finegan BA, Koshal A. Magnesium sulfate prophylaxis after cardiac operations. Ann Thorac Surg 1995; 59: 502-07.
29. White BC, Winegar CD, Wilson RF, Krause GS. Calcium blockers in cerebral resuscitation. J Trauma 1983; 23: 788-94.
30. Schwartz AC. Neurological recovery after cardiac arrest: clinical feasibility trial of calcium blockers. Am J Emerg Med 1985; 3: 1-10.
31. Hamburg RS, Ballin SD. Congress moves to address emergency cardiac care issues. Circulation 1995; 92: 149-41.
32. Jaffe AS, Landau WM. Death after death: the presumption of informed consent for cardiopulmonary resuscitation - ethical paradox and clinical conundrum. Neurology 1993; 43: 2173-78.