Loss of dorsal root ganglion cells concomitant with dorsal root axon sprouting following segmental nerve lesions

Neuroscience

Volumn 81, Issue 2, 1997, Pages 527-534

  Lekan, H A ^a   Chung, K ^a,b   Yoon, Y W ^a,d   Chung, J M ^a,b,c   Coggeshall, R E ^b,c  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^d Korea University College of Medicine   (South Korea)

Author keywords

Neuropathic pain; Numbers; Peripheral nerve injury; Primary afferents

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; MYELINATION; NERVE LESION; NERVE LIGATION; NERVE SPROUTING; NEUROPATHY; NONHUMAN; PRIMARY AFFERENT DEPOLARIZATION; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

ANIMALS; AXONS; CELL COUNT; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; LIGATION; MALE; PERIPHERAL NERVOUS SYSTEM; RATS;

EID: 0031559953     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00173-5     Document Type: Article

References (44)

1. Aldskogius H., Arvidsson J. Nerve cell degeneration and death in the trigeminal ganglion of the adult rat following peripheral nerve transection. J. Neurocytol. 7:1978;229-250.
2. Aldskogius H., Arvidsson J., Grant G. The reaction of primary sensory neurons to peripheral nerve injury with particular emphasis on transganglionic changes. Brain Res. 357:1985;27-46.
3. Arvidsson J., Ygge J., Grant G. Cell loss in lumbar dorsal root ganglia and transganglionic degeneration after sciatic nerve resection in the rat. Brain Res. 373:1986;15-21.
4. Averill S., McMahon S. B., Clary D. O., Reichardt L. F., Priestley J. V. Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons. Eur. J. Neurosci. 7:1995;1484-1494.
5. Carlson J., Lais A. C., Dyck P. J. Axonal atrophy from permanent peripheral axotomy in adult cat. J. Neuropath. exp. Neurol. 38:1979;579-585.
6. Carroll S. L., Silos-Santiago I., Frese S. E., Ruit K. G., Milbrandt J., Snider W. D. Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero. Neuron. 9:1992;779-788.
7. Choi Y., Yoon Y. W., Na H. S., Kim S. H., Chung J. M. Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain. Pain. 59:1994;369-376.
8. Chung K., Kim H. J., Na H. S., Park M. J., Chung J. M. Abnormalities of sympathetic innervation in the area of an injured peripheral nerve in a rat model of neuropathic pain. Neurosci. Lett. 162:1993;85-88.
9. Coggeshall R. E., Lekan H. A. Methods for determining numbers of cells and synapses: A case for more uniform standards of review. J. comp. Neurol. 364:1996;6-15.
10. Coggeshall R. E., Lekan H. A., Doubell T. P., Allchorne A., Woolf C. J. Central changes in primary afferent fibres following peripheral nerve lesions. Neuroscience. 77:1997;1115-1122.
11. Devor M., Govrin-Lippmann R., Frank I., Raber P. Proliferation of primary sensory neurons in adult rat dorsal root ganglion and the kinetics of retrograde cell loss after sciatic nerve section. Somatosensory Res. 3:1985;139-167.
12. Feringa E. R., Lee G. W., Vahlsing H. L., Gilbertie W. J. Cell death in the adult rat dorsal root ganglion after hind limb amputation, spinal cord transection, or both operations. Expl Neurol. 87:1985;349-357.
13. Gracely R. H., Lynch S. A., Bennett G. J. Painful neuropathy: altered central processing maintained dynamically by peripheral input. Pain. 51:1992;175-194.
14. Gundersen H. J., Bagger P., Bendtsen T. F., Evans S. M., Korbo L., Marcussen N., Moller A., Nielsen K., Nyengaard J. R., Pakkenberg B. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. Acta Path. Microbiol. Immunol. Scand. 96:1988;857-881.
15. Himes B. T., Tessler A. Death of some dorsal root ganglion neurons and plasticity of others following sciatic nerve section in adult and neonatal rats. J. comp. Neurol. 284:1989;215-230.
16. Kim S. H., Chung J. M. Sympathectomy alleviates mechanical allodynia in an experimental animal model for neuropathy in the rat. Neurosci. Lett. 134:1991;131-134.
17. Kim S. H., Chung J. M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain. 50:1992;355-363.
18. Kim S. H., Na H. S., Sheen K., Chung J. M. Effects of sympathectomy on a rat model of peripheral neuropathy. Pain. 55:1993;85-92.
19. Klein R., Silos-Santiago I., Smeyne R. J., Lira S. A., Brambilla R., Bryant S., Zhang L., Snider W. D., Barbacid M. Disruption of the neurotrophin-3 receptor gene trkC eliminates 1a muscle afferents and results in abnormal movements. Nature. 368:1994;249-251.
20. Lekan H. A., Carlton S. M., Coggeshall R. E. Sprouting of Aβ fibers into lamina II of the rat dorsal horn in peripheral neuropathy. Neurosci. Lett. 208:1996;147-150.
21. McNeill D. L., Carlton S. M., Coggeshall R. E., Hulsebosch C. E. Denervation-induced intraspinal synaptogenesis of calcitonin gene-related peptide containing primary afferent terminals. J. comp. Neurol. 296:1990;263-268.
22. McNeill D. L., Carlton S. M., Hulsebosch C. E. Intraspinal sprouting of calcitonin gene-related peptide containing primary afferents after deafferentation in the rat. Expl Neurol. 114:1991;321-329.
23. McNeill D. L., Hulsebosch C. E. Intraspinal sprouting of rat primary afferents after deafferentation. Neurosci. Lett. 81:1987;57-62.
24. Melville S., Sherburn T. E., Coggeshall R. E. Preservation of sensory cells by placing stumps of transected nerve in an impermeable tube. Expl Neurol. 105:1989;311-315.
25. Mu X., Silos-Santiago I., Carroll S. L., Snider W. D. Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia. J. Neurosci. 13:1993;4029-4041.
26. Na H. S., Leem J. W., Chung J. M. Abnormalities of mechanoreceptors in a rat model of neuropathic pain: possible involvement in mediating mechanical allodynia. J. Neurophysiol. 70:1993;522-528.
27. Otto D., Unsicker K., Grothe C. Pharmacological effects of nerve growth factor and fibroblast growth factor applied to the transectioned sciatic nerve on neuron death in adult rat dorsal root ganglia. Neurosci. Lett. 83:1987;156-160.
28. Rich K. M., Alexander T. D., Pryor J. C., Hollowell J. P. Nerve growth factor enhances regeneration through silicone chambers. Expl Neurol. 105:1989;162-170.
29. Rich K. M., Luszczynski J. R., Osborne P. A., Johnson E. M. Jr. Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injury. J. Neurocytol. 16:1987;261-268.
30. Risling M., Aldskogius H., Hildebrand C., Remahl S. Effects of sciatic nerve resection on L7 spinal roots and dorsal root ganglia in adult cats. Expl Neurol. 82:1983;568-580.
31. Ruit K. G., Elliott J. L., Osborne P. A., Yan Q., Snider W. D. Selective dependence of mammalian dorsal root ganglion neurons on nerve growth factor during embryonic development. Neuron. 8:1992;573-587.
32. Schmalbruch H. Loss of sensory neurons after sciatic nerve section in the rat. Anat. Rec. 219:1987;323-329.
33. Sheen K., Chung J. M. Signs of neuropathic pain depend on signals from injured nerve fibers in a rat model. Brain Res. 610:1993;62-68.
34. Steel J. H., Terenghi G., Chung J. M., Na H. S., Carlton S. M., Polak J. M. Increased nitric oxide synthase immunoreactivity in rat dorsal root ganglia in a neuropathic pain model. Neurosci. Lett. 169:1994;81-84.
35. Wesselmann U., Lin S. F., Rymer W. Z. Selective decrease of small sensory neurons in lumbar dorsal root ganglia labeled with horseradish peroxidase after ND:YAG laser irradiation of the tibial nerve in the rat. Expl Neurol. 111:1991;251-262.
36. West M. J., Slomianka L., Gundersen H. J. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231:1991;482-497.
37. Willis W. D. and Coggeshall R. E. (1991) Sensory Mechanisms of the Spinal Cord. 2nd edn, pp. 1-565, Plenum, New York.
38. Woolf C. J., Doubell T. P. The pathophysiology of chronic pain-increased sensitivity to low threshold A beta-fibre inputs. Curr. Opin. Neurobiol. 4:1994;525-534.
39. Woolf C. J., Reynolds M. L., Molander C., O'Brien C., Lindsay R. M., Benowitz L. I. The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury. Neuroscience. 34:1990;465-478.
40. Woolf C. J., Shortland P., Coggeshall R. E. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature. 355:1992;75-78.
41. Woolf C. J., Shortland P., Reynolds M., Ridings J., Doubell T., Coggeshall R. E. Reorganization of central terminals of myelinated primary afferents in the rat dorsal horn following peripheral axotomy. J. comp. Neurol. 360:1995;121-131.
42. Wright D. E., Snider W. D. Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia. J. comp. Neurol. 351:1995;329-338.
43. Ygge J. Neuronal loss in lumbar dorsal root ganglia after proximal compared to distal sciatic nerve resection: a quantitative study in the rat. Brain Res. 478:1989;193-195.
44. Yoon Y. W., Na H. S., Chung J. M. Contributions of injured and intact afferents to neuropathic pain in an experimental rat model. Pain. 64:1996;27-36.