-
1
-
-
0023143218
-
Evaluation of models for analysis of radioligand binding data
-
ABRAMSON, S. N., MCGONIGLE, P. & MOLINOFF, P. B. (1987). Evaluation of models for analysis of radioligand binding data. Mol. Pharmacol. 31, 103-111.
-
(1987)
Mol. Pharmacol.
, vol.31
, pp. 103-111
-
-
Abramson, S.N.1
McGonigle, P.2
Molinoff, P.B.3
-
2
-
-
0023205408
-
An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover
-
ASHKENAZI, A., WINSLOW, J. W., PERALTA, E. G., PETERSON, G. L., SCHIMERLIK, M. I., CAPON, D. J. & RAMACHANDRAN, J. (1987). An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover. Science 238, 672-675.
-
(1987)
Science
, vol.238
, pp. 672-675
-
-
Ashkenazi, A.1
Winslow, J.W.2
Peralta, E.G.3
Peterson, G.L.4
Schimerlik, M.I.5
Capon, D.J.6
Ramachandran, J.7
-
5
-
-
0024427734
-
The transitory complex between photoexcited rhodopsin and transducin
-
BORNANCIN, F., PFISTER, C. & CHABRE, M. (1989). The transitory complex between photoexcited rhodopsin and transducin. Eur. J. Biochem. 184, 687-698.
-
(1989)
Eur. J. Biochem.
, vol.184
, pp. 687-698
-
-
Bornancin, F.1
Pfister, C.2
Chabre, M.3
-
6
-
-
0029976453
-
Conformational induction versus conformational selection: Evidence from allosteric enhancers
-
BRUNS, R. F. (1996). Conformational induction versus conformational selection: evidence from allosteric enhancers. Trends. Pharmacol. Sci. 17, 189.
-
(1996)
Trends. Pharmacol. Sci.
, vol.17
, pp. 189
-
-
Bruns, R.F.1
-
8
-
-
0023867394
-
G protein involvement in receptor-effector coupling
-
CASEY, P. J. & GILMAN, A. G. (1988). G protein involvement in receptor-effector coupling. J. Biol. Chem. 263, 2577-2580.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 2577-2580
-
-
Casey, P.J.1
Gilman, A.G.2
-
9
-
-
0027332132
-
BW373U86: A nonpeptidic δ-opioid agonist with novel receptor-G protein-mediated actions in rat brain membranes and neuroblastoma cells
-
CHILDERS, S. R., FLEMING, L. M., SELLEY, D. E., MCNUTT, R. W. & CHANG, K.-J. (1993). BW373U86: A nonpeptidic δ-opioid agonist with novel receptor-G protein-mediated actions in rat brain membranes and neuroblastoma cells. Mol. Pharmacol. 44, 827-834.
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 827-834
-
-
Childers, S.R.1
Fleming, L.M.2
Selley, D.E.3
McNutt, R.W.4
Chang, K.-J.5
-
10
-
-
0019137579
-
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor
-
DE LEAN, A., STADEL, J. M. & LEFKOWITZ, R. J. (1980) A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor. J. Biol. Chem. 255, 7108-7117.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 7108-7117
-
-
De Lean, A.1
Stadel, J.M.2
Lefkowitz, R.J.3
-
11
-
-
0025311683
-
Signaling through the muscarinic receptor-adenylate cyclase system of the heart is buffered against GTP over a range of concentrations
-
EHLERT, F. J. & RATHBUN, B. E. (1990). Signaling through the muscarinic receptor-adenylate cyclase system of the heart is buffered against GTP over a range of concentrations. Mol. Pharmacol. 38, 148-158.
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 148-158
-
-
Ehlert, F.J.1
Rathbun, B.E.2
-
12
-
-
0025036350
-
Rhodopsin mutants that bind but fail to activate transducin
-
FRANKE, R. R., KÖNIG, B., SAKMAR, T. P., KHORANA, H. G. & HOFMANN, K. P. (1990). Rhodopsin mutants that bind but fail to activate transducin. Science 250, 123-125.
-
(1990)
Science
, vol.250
, pp. 123-125
-
-
Franke, R.R.1
König, B.2
Sakmar, T.P.3
Khorana, H.G.4
Hofmann, K.P.5
-
14
-
-
0027283546
-
Partial agonists, full agonists, antagonists: Dilemmas of definition
-
HOYER, D. & BODDEKE, H. W. G. M. (1993). Partial agonists, full agonists, antagonists: dilemmas of definition. Trends Pharmacol. 14, 270-275.
-
(1993)
Trends Pharmacol.
, vol.14
, pp. 270-275
-
-
Hoyer, D.1
Boddeke, H.W.G.M.2
-
15
-
-
0029061611
-
Agonist-receptor efficacy I: Mechanisms of efficacy and receptor promiscuity
-
KENAKIN, T. (1995a). Agonist-receptor efficacy I: mechanisms of efficacy and receptor promiscuity. Trends. Pharmacol. Sci. 16, 188-192.
-
(1995)
Trends. Pharmacol. Sci.
, vol.16
, pp. 188-192
-
-
Kenakin, T.1
-
16
-
-
0029054965
-
Agonist-receptor efficacy II: Agonist trafficking of receptor signals
-
KENAKIN, T. (1995b). Agonist-receptor efficacy II: agonist trafficking of receptor signals. Trends. Pharmacol. Sci. 16, 232-238.
-
(1995)
Trends. Pharmacol. Sci.
, vol.16
, pp. 232-238
-
-
Kenakin, T.1
-
17
-
-
0029976454
-
Receptor conformational induction versus selection: All part of the same energy landscape
-
KENAKIN, T. (1996). Receptor conformational induction versus selection: all part of the same energy landscape. Trends. Pharmacol. Sci. 17, 190-191.
-
(1996)
Trends. Pharmacol. Sci.
, vol.17
, pp. 190-191
-
-
Kenakin, T.1
-
18
-
-
0029664589
-
The 2.0 Å crystal structure of a heterotrimeric G protein
-
LAMBRIGHT, D. G., SONDEK, J., BOHM, A., SKIBA, N. P., HAMM, H. E. & SIGLER, P. B. (1996). The 2.0 Å crystal structure of a heterotrimeric G protein. Nature 379, 311-319.
-
(1996)
Nature
, vol.379
, pp. 311-319
-
-
Lambright, D.G.1
Sondek, J.2
Bohm, A.3
Skiba, N.P.4
Hamm, H.E.5
Sigler, P.B.6
-
19
-
-
0027313323
-
35S]GTPγS binding mediated by human muscarinic m1-m4 receptors: Antagonist studies
-
35S]GTPγS binding mediated by human muscarinic m1-m4 receptors: antagonist studies. Br. J. Pharmacol. 109, 1120-1127.
-
(1993)
Br. J. Pharmacol.
, vol.109
, pp. 1120-1127
-
-
Lazareno, S.1
Birdsall, N.J.M.2
-
20
-
-
0027297275
-
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
-
LEFKOWITZ, R. J., COTECCHIA, S., SAMAMA, P. & COSTA, T. (1993). Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol. Sci. 141, 303-307.
-
(1993)
Trends Pharmacol. Sci.
, vol.141
, pp. 303-307
-
-
Lefkowitz, R.J.1
Cotecchia, S.2
Samama, P.3
Costa, T.4
-
21
-
-
0025190558
-
Interpretation of relative potencies, relative efficacies and apparent affinity constants of agonist drugs estimated from concentration-response curves
-
MACKAY, D. (1990). Interpretation of relative potencies, relative efficacies and apparent affinity constants of agonist drugs estimated from concentration-response curves. J. theor. Biol. 142, 415-427.
-
(1990)
J. Theor. Biol.
, vol.142
, pp. 415-427
-
-
Mackay, D.1
-
22
-
-
0024501089
-
2 muscarinic receptors that are separately coupled to two biochemical effector systems
-
2 muscarinic receptors that are separately coupled to two biochemical effector systems. Mol. Pharmacol. 35, 39-47.
-
(1989)
Mol. Pharmacol.
, vol.35
, pp. 39-47
-
-
McKinney, M.1
Anderson, D.2
Vella-Rountree, L.3
-
23
-
-
0024430454
-
1 muscarinic receptor and the hydrolysis of inositol lipids in transfected murine fibroblast cells (B82) expressing different receptor densities
-
1 muscarinic receptor and the hydrolysis of inositol lipids in transfected murine fibroblast cells (B82) expressing different receptor densities. J. Pharmacol. Exp. Ther. 251, 90-97.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.251
, pp. 90-97
-
-
Mei, L.1
Lai, J.2
Yamamura, H.I.3
Roeske, W.R.4
-
24
-
-
0028305892
-
Differential regulation of cAMP-mediated gene transcription by m1 and m4 muscarinic acetylcholine receptors
-
MIGEON, J. C. & NATHANSON, N. M. (1994). Differential regulation of cAMP-mediated gene transcription by m1 and m4 muscarinic acetylcholine receptors. J. Biol. Chem. 269, 9767-9773.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 9767-9773
-
-
Migeon, J.C.1
Nathanson, N.M.2
-
26
-
-
0023893103
-
2-adrenergic receptors: Evidence for a precoupled receptor-guanine nucleotide protein complex
-
2-adrenergic receptors: evidence for a precoupled receptor-guanine nucleotide protein complex. Biochemistry 27, 2374-2384.
-
(1988)
Biochemistry
, vol.27
, pp. 2374-2384
-
-
Neubig, R.R.1
Gantzos, R.D.2
Thomsen, W.J.3
-
27
-
-
0027497536
-
βγ subunits of guanine nucleotide-binding proteins and regulation of spontaneous receptor activity: Thermodynamic model for the interaction between receptors and guanine nucleotide-binding protein subunits
-
ONARAN, H. O., COSTA, T. & RODBARD, D. (1993). βγ subunits of guanine nucleotide-binding proteins and regulation of spontaneous receptor activity: thermodynamic model for the interaction between receptors and guanine nucleotide-binding protein subunits. Mol. Pharmacol. 43, 245-256.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 245-256
-
-
Onaran, H.O.1
Costa, T.2
Rodbard, D.3
-
32
-
-
0028337644
-
Deletion analysis of the m4 muscarinic acetylcholine receptor
-
VAN KOPPEN, C. J., SELL, A., LENZ, W. & JAKOBS, K. H. (1994). Deletion analysis of the m4 muscarinic acetylcholine receptor. Eur. J. Biochem. 222, 525-531.
-
(1994)
Eur. J. Biochem.
, vol.222
, pp. 525-531
-
-
Van Koppen, C.J.1
Sell, A.2
Lenz, W.3
Jakobs, K.H.4
-
34
-
-
0029012939
-
Porcine m2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells
-
VOGEL, W. K., MOSSER, V. A., BULSECO, D. A. & SCHIMERLIK, M. I. (1995). Porcine m2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells. J. Biol. Chem. 270, 15485-15493.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15485-15493
-
-
Vogel, W.K.1
Mosser, V.A.2
Bulseco, D.A.3
Schimerlik, M.I.4
-
35
-
-
0029593456
-
1γ2
-
1γ2. Cell 83, 1047-1058.
-
(1995)
Cell
, vol.83
, pp. 1047-1058
-
-
Wall, M.A.1
Coleman, D.E.2
Lee, E.3
Iñiguez-Lhuhi, J.A.4
Posner, B.A.5
Gilman, A.G.6
Sprang, S.R.7
-
36
-
-
0029935383
-
The cubic ternary complex receptor-occupancy model. I. Model description
-
WEISS, J. M., MORGAN, P. H., LUTZ, M. W. & KENAKIN, T. P. (1996a). The cubic ternary complex receptor-occupancy model. I. Model description. J. theor. Biol. 178, 151-167.
-
(1996)
J. Theor. Biol.
, vol.178
, pp. 151-167
-
-
Weiss, J.M.1
Morgan, P.H.2
Lutz, M.W.3
Kenakin, T.P.4
-
37
-
-
0029983553
-
The cubic ternary complex receptor-occupancy model. II. Understanding apparent affinity
-
WEISS, J. M., MORGAN, P. H., LUTZ, M. W. & KENAKIN, T. P. (1996b). The cubic ternary complex receptor-occupancy model. II. Understanding apparent affinity. J. theor. Biol. 178, 169-182.
-
(1996)
J. Theor. Biol.
, vol.178
, pp. 169-182
-
-
Weiss, J.M.1
Morgan, P.H.2
Lutz, M.W.3
Kenakin, T.P.4
-
38
-
-
0030596736
-
The cubic ternary complex receptor-occupancy model. III. Resurrecting efficacy
-
WEISS, J. M., MORGAN, P. H., LUTZ, M. W. & KENAKIN, T. P. (1996c). The cubic ternary complex receptor-occupancy model. III. Resurrecting efficacy. J. theor. Biol. 181, 381-397.
-
(1996)
J. Theor. Biol.
, vol.181
, pp. 381-397
-
-
Weiss, J.M.1
Morgan, P.H.2
Lutz, M.W.3
Kenakin, T.P.4
-
39
-
-
0028314995
-
Measurement of receptor-stimulated guanosine 5′0-(γ-Thio)triphosphate binding by G proteins
-
WIELAND, T. & JAKOBS, K. H. (1994). Measurement of receptor-stimulated guanosine 5′0-(γ-Thio)triphosphate binding by G proteins. Meth. Enzymol. 237, 3-15.
-
(1994)
Meth. Enzymol.
, vol.237
, pp. 3-15
-
-
Wieland, T.1
Jakobs, K.H.2
|