메뉴 건너뛰기




Volumn 126, Issue 2, 1997, Pages 153-163

Essential promoter elements are located within the 5' untranslated region of human insulin-like growth factor-I exon I

Author keywords

Insulin like growth factor I; Promotor function; Untranslated region

Indexed keywords

DNA; DNA BINDING PROTEIN; LUCIFERASE; NUCLEAR PROTEIN; SOMATOMEDIN C;

EID: 0031557104     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(96)03979-2     Document Type: Article
Times cited : (56)

References (40)
  • 2
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones, J.I. and Clemmons, D.R. (1995) Insulin-like growth factors and their binding proteins: Biological actions. Endocr. Rev. 16, 3-34.
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 4
    • 0026408764 scopus 로고
    • Structure and function of a human insulin-like growth factor-I gene promoter
    • Kim, S.W., Lajara, R. and Rotwein, P. (1991) Structure and function of a human insulin-like growth factor-I gene promoter. Mol. Endocrinol. 5, 1964-1972.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1964-1972
    • Kim, S.W.1    Lajara, R.2    Rotwein, P.3
  • 5
    • 0028915503 scopus 로고
    • Regulation of insulin-like growth factor I gene expression. Implications for normal and pathological growth
    • Adamo, M.L. (1995) Regulation of insulin-like growth factor I gene expression. Implications for normal and pathological growth. Diabetes Rev. 3, 2-27.
    • (1995) Diabetes Rev. , vol.3 , pp. 2-27
    • Adamo, M.L.1
  • 6
    • 0025856373 scopus 로고
    • Structure, evolution, expression and regulation of insulin-like growth factors I and II
    • Rotwein, P. (1991) Structure, evolution, expression and regulation of insulin-like growth factors I and II. Growth Factors 5, 3-18.
    • (1991) Growth Factors , vol.5 , pp. 3-18
    • Rotwein, P.1
  • 7
    • 0026801525 scopus 로고
    • Chromatin changes accompany the developmental activation of insulin-like growth factor I gene transcription
    • Kikuchi, K., Bichell, D.P. and Rotwein, P. (1992) Chromatin changes accompany the developmental activation of insulin-like growth factor I gene transcription. J. Biol. Chem. 267, 21505-21511.
    • (1992) J. Biol. Chem. , vol.267 , pp. 21505-21511
    • Kikuchi, K.1    Bichell, D.P.2    Rotwein, P.3
  • 8
    • 0006789567 scopus 로고
    • Regulation of insulin-like growth factor I gene expression by growth hormone
    • Mathews, L.S., Norstedt, G. and Palmiter, R.D. (1986) Regulation of insulin-like growth factor I gene expression by growth hormone. Proc. Natl. Acad. Sci. USA 83, 9343-9347.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9343-9347
    • Mathews, L.S.1    Norstedt, G.2    Palmiter, R.D.3
  • 9
    • 0023661333 scopus 로고
    • Acute regulation of insulin-like growth factor-I gene expression by growth hormone during adipose cell differentiation
    • Doglio, A., Dani, C., Fredrikson, G., Grimaldi, P. and Aihaud, G. (1987) Acute regulation of insulin-like growth factor-I gene expression by growth hormone during adipose cell differentiation. EMBO J. 6, 4011-4016.
    • (1987) EMBO J. , vol.6 , pp. 4011-4016
    • Doglio, A.1    Dani, C.2    Fredrikson, G.3    Grimaldi, P.4    Aihaud, G.5
  • 10
    • 0026482165 scopus 로고
    • Growth hormone rapidly activates insulin-like growth faactor I gene transcription in vivo
    • Bichell, D.P., Kikuchi, K. and Rotwein, P. (1992) Growth hormone rapidly activates insulin-like growth faactor I gene transcription in vivo. Mol. Endocrinol. 6, 1899-1908.
    • (1992) Mol. Endocrinol , vol.6 , pp. 1899-1908
    • Bichell, D.P.1    Kikuchi, K.2    Rotwein, P.3
  • 11
    • 0027337594 scopus 로고
    • 2 rapidly stimulates insulin-like growth factor I gene expression in primary rat osteoblast cultures: Evidence for transcriptional control
    • 2 rapidly stimulates insulin-like growth factor I gene expression in primary rat osteoblast cultures: evidence for transcriptional control. Endocrinology 132, 1020-1028.
    • (1993) Endocrinology , vol.132 , pp. 1020-1028
    • Bichell, D.P.1    Rotwein, P.2    McCarthy, T.L.3
  • 12
    • 0029090980 scopus 로고
    • Regulation of insulin-like growth factor I transcription by cyclic adenosine 3′5′-monophosphate (cAMP) in fetal rat bone cells through an element within exon 1: Protein kinase A-dependent control without a consensus AMP response element
    • McCarthy, T.L., Thomas, M.J., Centrella, M. and Rotwein, P. (1995) Regulation of insulin-like growth factor I transcription by cyclic adenosine 3′5′-monophosphate (cAMP) in fetal rat bone cells through an element within exon 1: Protein kinase A-dependent control without a consensus AMP response element. Endocrinology 136, 3901-3908.
    • (1995) Endocrinology , vol.136 , pp. 3901-3908
    • McCarthy, T.L.1    Thomas, M.J.2    Centrella, M.3    Rotwein, P.4
  • 14
    • 0024315391 scopus 로고
    • Insulin-like growth factor I messenger ribonucleic acids with alternative 5′-untranslated regions are differentially expressed during development of the rat
    • Adamo, M.L., Lowe Jr., W.L., LeRoith, D. and Roberts Jr., C.T. (1989) Insulin-like growth factor I messenger ribonucleic acids with alternative 5′-untranslated regions are differentially expressed during development of the rat. Endocrinology 124, 2737-2744.
    • (1989) Endocrinology , vol.124 , pp. 2737-2744
    • Adamo, M.L.1    Lowe W.L., Jr.2    LeRoith, D.3    Roberts C.T., Jr.4
  • 15
    • 0023700261 scopus 로고
    • Tissue and devlopment specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids
    • Hoyt, E.C., Van Wyck, J.J. and Lund, P.K. (1988) Tissue and devlopment specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids. Mol. Endocrinol. 2, 1077-1086.
    • (1988) Mol. Endocrinol. , vol.2 , pp. 1077-1086
    • Hoyt, E.C.1    Van Wyck, J.J.2    Lund, P.K.3
  • 16
    • 0025838403 scopus 로고
    • Regulation of start site usage in the leader exons of the rat insulin-like growth factor-I gene by development, fasting, and diabetes
    • Adamo, M.L., Ben-Hur, H., Roberts Jr., C.T. and LeRoith, D. (1991) Regulation of start site usage in the leader exons of the rat insulin-like growth factor-I gene by development, fasting, and diabetes. Mol. Endocrinol. 5, 1677-1686.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1677-1686
    • Adamo, M.L.1    Ben-Hur, H.2    Roberts C.T., Jr.3    LeRoith, D.4
  • 17
    • 0027412808 scopus 로고
    • Characterization of multiple transcription initiation sites of the ovine insulin-like growth factor-I gene and expression profiles of three alternatively spliced transcripts
    • Ohlsen, S.M., Dean, D.M. and Wong, E.A. (1993) Characterization of multiple transcription initiation sites of the ovine insulin-like growth factor-I gene and expression profiles of three alternatively spliced transcripts. DNA Cell Biol. 12, 243-251.
    • (1993) DNA Cell Biol. , vol.12 , pp. 243-251
    • Ohlsen, S.M.1    Dean, D.M.2    Wong, E.A.3
  • 18
    • 0027525546 scopus 로고
    • The porcine insulin-like growth factor-I gene: Characterization and expression of alternate transcription sites
    • Weller, P.A., Dickson, M.C., Huskisson, N.S., Dauncey, M.J., Buttery, P.J. and Gilmour, R.S. (1993) The porcine insulin-like growth factor-I gene: Characterization and expression of alternate transcription sites. J. Mol. Endocrinol. 11, 201-211.
    • (1993) J. Mol. Endocrinol. , vol.11 , pp. 201-211
    • Weller, P.A.1    Dickson, M.C.2    Huskisson, N.S.3    Dauncey, M.J.4    Buttery, P.J.5    Gilmour, R.S.6
  • 19
    • 0026095213 scopus 로고
    • Expression of a growth hormone-responsive exon of the ovine insulin-like growth factor-I gene
    • Saunders, J.C., Dickson, M.C., Pell, J.M. and Gilmour, R.S. (1991) Expression of a growth hormone-responsive exon of the ovine insulin-like growth factor-I gene. J. Mol. Endocrinol. 7, 233-240.
    • (1991) J. Mol. Endocrinol. , vol.7 , pp. 233-240
    • Saunders, J.C.1    Dickson, M.C.2    Pell, J.M.3    Gilmour, R.S.4
  • 20
    • 0025904847 scopus 로고
    • Identification of multiple transcription start sites in the human insulin-like growth factor-I gene
    • Jansen, E., Steenbergh, P.H., LeRoith, D., Roberts Jr., C.T. and Sussenbach, J.S. (1991) Identification of multiple transcription start sites in the human insulin-like growth factor-I gene. Mol. Cell. Endocrinol. 78, 115-125.
    • (1991) Mol. Cell. Endocrinol. , vol.78 , pp. 115-125
    • Jansen, E.1    Steenbergh, P.H.2    LeRoith, D.3    Roberts C.T., Jr.4    Sussenbach, J.S.5
  • 21
    • 0025895753 scopus 로고
    • Structure of the chicken insulin-like growth factor I gene reveals conserved promoter elements
    • Kajimoto, Y. and Rotwein, P. (1991) Structure of the chicken insulin-like growth factor I gene reveals conserved promoter elements. J. Biol. Chem. 266, 9724-9731.
    • (1991) J. Biol. Chem. , vol.266 , pp. 9724-9731
    • Kajimoto, Y.1    Rotwein, P.2
  • 22
    • 0025813252 scopus 로고
    • Differential association of insulin-like growth factor I mRNA variants with polysomes in vivo
    • Foyt, H.L., LeRoith, D. and Roberts Jr, C.T. (1991) Differential association of insulin-like growth factor I mRNA variants with polysomes in vivo. J. Biol. Chem. 266, 7300-7305.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7300-7305
    • Foyt, H.L.1    LeRoith, D.2    Roberts C.T., Jr.3
  • 23
    • 0029124241 scopus 로고
    • Alternative leader sequences in insulin-like growth factor I mRNAs modulate translational efficiency and encode multiple signal peptides
    • Yang, H., Adamo, M.L., Koval, A.P., McGuiness, M.C., Ben-Hur, H., Yang, Y., LeRoith, D. and Roberts, C.T. (1995) Alternative leader sequences in insulin-like growth factor I mRNAs modulate translational efficiency and encode multiple signal peptides. Mol. Endocrinol. 9, 1380-1395.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1380-1395
    • Yang, H.1    Adamo, M.L.2    Koval, A.P.3    McGuiness, M.C.4    Ben-Hur, H.5    Yang, Y.6    LeRoith, D.7    Roberts, C.T.8
  • 24
    • 0023078285 scopus 로고
    • Identification of regulatory elements of cloned genes with functional assays
    • Rosenthal, N. (1987) Identification of regulatory elements of cloned genes with functional assays. Methods Enzymol. 152, 704-720.
    • (1987) Methods Enzymol. , vol.152 , pp. 704-720
    • Rosenthal, N.1
  • 25
    • 0024829771 scopus 로고
    • Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines
    • Brasier, A.R., Tate, J.E. and Habener, J.F. (1989) Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. Biotechniques 7, 1116-1122.
    • (1989) Biotechniques , vol.7 , pp. 1116-1122
    • Brasier, A.R.1    Tate, J.E.2    Habener, J.F.3
  • 26
    • 0023895357 scopus 로고
    • A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing
    • Lee, K.A.W., Bindereif, A. and Green, M.R. (1988) A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing. Gene Anal. Techn. 5, 22-31.
    • (1988) Gene Anal. Techn. , vol.5 , pp. 22-31
    • Lee, K.A.W.1    Bindereif, A.2    Green, M.R.3
  • 27
    • 0027994214 scopus 로고
    • Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no alterations in deoxyribonucleic acid-protein interactions within the major promoter
    • Thomas, M.J., Kikuchi, K., Bichell, D.P. and Rotwein, P. (1994) Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no alterations in deoxyribonucleic acid-protein interactions within the major promoter. Endocrinology 135, 1584-1592.
    • (1994) Endocrinology , vol.135 , pp. 1584-1592
    • Thomas, M.J.1    Kikuchi, K.2    Bichell, D.P.3    Rotwein, P.4
  • 28
    • 0028906741 scopus 로고
    • Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no changes in deoxyribonucleis acid-protein interactions within the second promoter
    • Le Stunff, C., Thomas, M.J. and Rotwein, P. (1995) Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no changes in deoxyribonucleis acid-protein interactions within the second promoter. Endocrinology 136, 2230-2237.
    • (1995) Endocrinology , vol.136 , pp. 2230-2237
    • Le Stunff, C.1    Thomas, M.J.2    Rotwein, P.3
  • 29
    • 0028966145 scopus 로고
    • Characterization of deoxyribonucleic acid-protein interactions at a growth hormone-inducible nuclease hypersensitive site in the rat insulin-like growth factor I gene
    • Thomas, M.J., Kikuchi, K., Bichell, D.P. and Rotwein, P. (1995) Characterization of deoxyribonucleic acid-protein interactions at a growth hormone-inducible nuclease hypersensitive site in the rat insulin-like growth factor I gene. Endocrinology 136, 562-569.
    • (1995) Endocrinology , vol.136 , pp. 562-569
    • Thomas, M.J.1    Kikuchi, K.2    Bichell, D.P.3    Rotwein, P.4
  • 30
    • 0027397529 scopus 로고
    • Distinct promoters in the rat insulin-like growth factor-I (IGF-I) gene are active in CHO cells
    • Adamo, M.L., Lanau, F., Neuenschwander, S., Werner, H., LeRoith, D. and Roberts Jr., C.T. (1993) Distinct promoters in the rat insulin-like growth factor-I (IGF-I) gene are active in CHO cells. Endocrinology 132, 935-937.
    • (1993) Endocrinology , vol.132 , pp. 935-937
    • Adamo, M.L.1    Lanau, F.2    Neuenschwander, S.3    Werner, H.4    LeRoith, D.5    Roberts C.T., Jr.6
  • 31
    • 0028605954 scopus 로고
    • Expression of the insulin-like growth factor I gene is stimulated by the liver-enriched transcription factors C/EBPa and LAP
    • Nolten, L.A., Van Schaik, F.M.A., Steenburgh, P.H. and Sussenbach, J.S. (1994) Expression of the insulin-like growth factor I gene is stimulated by the liver-enriched transcription factors C/EBPa and LAP. Mol. Endocrinol. 8, 1636-1645.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1636-1645
    • Nolten, L.A.1    Van Schaik, F.M.A.2    Steenburgh, P.H.3    Sussenbach, J.S.4
  • 32
    • 0028810322 scopus 로고
    • Hepatocyte nuclear factor 1a activates promoter 1 of the human insulin-like growth factor I gene via two distinct binding sites
    • Nolten, L.A., Steenburgh, P.H. and Sussenbach, J.S. (1995) Hepatocyte nuclear factor 1a activates promoter 1 of the human insulin-like growth factor I gene via two distinct binding sites. Mol. Endocrinol. 9, 1488-1499.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1488-1499
    • Nolten, L.A.1    Steenburgh, P.H.2    Sussenbach, J.S.3
  • 33
    • 0028802385 scopus 로고
    • The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression
    • An, M.R. and Lowe Jr., W.L. (1995) The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression. Mol. Cell. Endocrinol. 114, 77-89.
    • (1995) Mol. Cell. Endocrinol. , vol.114 , pp. 77-89
    • An, M.R.1    Lowe W.L., Jr.2
  • 34
    • 0028843141 scopus 로고
    • Identification of novel promoter and repressor elements in the 5′-flanking regions of the rat insulin-like growth factor-I gene
    • Huang, S., Thule, P.M. and Phillips, L.S. (1995) Identification of novel promoter and repressor elements in the 5′-flanking regions of the rat insulin-like growth factor-I gene. Biochem. Biophys. Res. Commun. 206, 279-286.
    • (1995) Biochem. Biophys. Res. Commun. , vol.206 , pp. 279-286
    • Huang, S.1    Thule, P.M.2    Phillips, L.S.3
  • 35
    • 0029930425 scopus 로고    scopus 로고
    • In vitro transcription of the rat insulin-like growth factor-I gene
    • Pao, C.-I., Lin, K.M., Zhu, J., Wu, G., Farmer, P.K. and Phillips, L.S. (1996) In vitro transcription of the rat insulin-like growth factor-I gene. J. Biol. Chem. 271, 8667-8674.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8667-8674
    • Pao, C.-I.1    Lin, K.M.2    Zhu, J.3    Wu, G.4    Farmer, P.K.5    Phillips, L.S.6
  • 36
    • 0025735101 scopus 로고
    • POU-domain transcription factors: Pou-er-ful developmental regulators
    • Rosenfeld, M.G. (1991) POU-domain transcription factors: Pou-er-ful developmental regulators. Genes Dev. 5, 897-907.
    • (1991) Genes Dev. , vol.5 , pp. 897-907
    • Rosenfeld, M.G.1
  • 37
    • 0025886340 scopus 로고
    • Octamania: The POU factors in murine development
    • Scholar, H.R. (1991) Octamania: The POU factors in murine development. TIG 7, 323-329.
    • (1991) TIG , vol.7 , pp. 323-329
    • Scholar, H.R.1
  • 38
    • 0024355048 scopus 로고
    • Insulin-like growth factors I and II. Peptide,messenger ribonucleic acid and gene structures, serum and tissue concentrations
    • Daughaday, W.H. and Rotwein, P. (1989) Insulin-like growth factors I and II. Peptide,messenger ribonucleic acid and gene structures, serum and tissue concentrations. Endocr. Rev. 10, 68-91.
    • (1989) Endocr. Rev. , vol.10 , pp. 68-91
    • Daughaday, W.H.1    Rotwein, P.2
  • 39
    • 0028848026 scopus 로고
    • In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3
    • Gronowski, A.M., Zhong, Z., Wen, Z., Thomas, M.J., Darnell Jr., J.E. and Rotwein, P. (1995) In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3. Mol. Endocrinol. 9, 171-177.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 171-177
    • Gronowski, A.M.1    Zhong, Z.2    Wen, Z.3    Thomas, M.J.4    Darnell J.E., Jr.5    Rotwein, P.6
  • 40
    • 0030064407 scopus 로고    scopus 로고
    • Acute nuclear actions of growth hormone (GH): Cycloheximide inhibits inducible activator protein-1 activity, but does not block GH-regulated signal transducer and activator of transcription activation or gene expression
    • Gronowski, A.M., Le Stunff, C. and Rotwein, P. (1996) Acute nuclear actions of growth hormone (GH): Cycloheximide inhibits inducible activator protein-1 activity, but does not block GH-regulated signal transducer and activator of transcription activation or gene expression. Endocrinology 137, 55-64.
    • (1996) Endocrinology , vol.137 , pp. 55-64
    • Gronowski, A.M.1    Le Stunff, C.2    Rotwein, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.