Preparation and characterization of novel poly(alkylamine)-based hydrogels designed for use as bile acid sequestrants

Macromolecules

Volumn 30, Issue 20, 1997, Pages 6174-6184

  Figuly, Garret D ^a   Royce, Susan D ^a   Khasat, Nitya P ^a   Schock, Laurel E ^a   Wu, Shilain D ^a   Davidson, Fredric ^a   Campbell Jr , G Creston ^a   Keating, Mimi Y ^a   Chen, Harry W ^a   Shimshick, Edward J ^a   Fischer, Robert T ^a   Grimminger, Lisa C ^a   Thomas, Beth E ^a   Smith, Linda H ^a   Gillies, Peter J ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; CROSSLINKING; POLYAMIDES; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL); THERMOANALYSIS; THERMODYNAMIC STABILITY;

BILE ACID SEQUESTRANTS; DIHALO COMPOUNDS; IONIC POLYAMMONIUM FORM; POLYALKYLAMINE;

HYDROGELS;

EID: 0031556525     PISSN: 00249297     EISSN: None     Source Type: Journal    
DOI: 10.1021/ma9702509     Document Type: Article

References (43)

1. Buchholz, F. L.; Peppas, N. A., Eds. Superabsorbent Polymers Science and Technology; ACS Symposium Series 573; American Chemical Society, Washington, DC, 1994.
2. Pó, R. J. Mater. Sci.-Rev. Macromol. Chem. Phys. 1994, C34 (4), 607.
3. DeRossi, D.; Kajiwara, K.; Osada, Y.; Yamauchi, A., Eds. Polymer Gels Fundamentals and Biomedical Applications; Plenum Press: New York and London, 1991.
4. For selected examples of applications, see: (a) Peppas, N. A.; Yang, W.-H. M. Contact Lens 1981, 7 (4), 300. (b) Ambrosio, L.; Netti, P. A.; Iannace, S.; Huang, S. J.; Nicolais, L. J. Mater. Sci: Mater. Med. 1996, 7, 251. (c) Laroche, L. Macromol. Symp. 1995, 51. (d) Cascone, M. G.; Laus, M.; Ricci, D.; Sbarbati Del Guerra, R. J. Mater. Sci.: Mater. Med. 1995, 6, 71. (e) Bellamkonda, R.; Ranieri, J. P.; Bouche, N.; Aebischer, P. J. Biomed. Mater. Res. 1995, 29, 663. (f) Woerly, S. Biomaterials 1993, 14 (14), 1056. (g) Ansell, C. W. G. Macromol. Rep. 1995, A32 (Suppl. 5 & 6), 733.
5. For selected examples of applications, see: (a) Peppas, N. A.; Yang, W.-H. M. Contact Lens 1981, 7 (4), 300. (b) Ambrosio, L.; Netti, P. A.; Iannace, S.; Huang, S. J.; Nicolais, L. J. Mater. Sci: Mater. Med. 1996, 7, 251. (c) Laroche, L. Macromol. Symp. 1995, 51. (d) Cascone, M. G.; Laus, M.; Ricci, D.; Sbarbati Del Guerra, R. J. Mater. Sci.: Mater. Med. 1995, 6, 71. (e) Bellamkonda, R.; Ranieri, J. P.; Bouche, N.; Aebischer, P. J. Biomed. Mater. Res. 1995, 29, 663. (f) Woerly, S. Biomaterials 1993, 14 (14), 1056. (g) Ansell, C. W. G. Macromol. Rep. 1995, A32 (Suppl. 5 & 6), 733.
6. For selected examples of applications, see: (a) Peppas, N. A.; Yang, W.-H. M. Contact Lens 1981, 7 (4), 300. (b) Ambrosio, L.; Netti, P. A.; Iannace, S.; Huang, S. J.; Nicolais, L. J. Mater. Sci: Mater. Med. 1996, 7, 251. (c) Laroche, L. Macromol. Symp. 1995, 51. (d) Cascone, M. G.; Laus, M.; Ricci, D.; Sbarbati Del Guerra, R. J. Mater. Sci.: Mater. Med. 1995, 6, 71. (e) Bellamkonda, R.; Ranieri, J. P.; Bouche, N.; Aebischer, P. J. Biomed. Mater. Res. 1995, 29, 663. (f) Woerly, S. Biomaterials 1993, 14 (14), 1056. (g) Ansell, C. W. G. Macromol. Rep. 1995, A32 (Suppl. 5 & 6), 733.
7. For selected examples of applications, see: (a) Peppas, N. A.; Yang, W.-H. M. Contact Lens 1981, 7 (4), 300. (b) Ambrosio, L.; Netti, P. A.; Iannace, S.; Huang, S. J.; Nicolais, L. J. Mater. Sci: Mater. Med. 1996, 7, 251. (c) Laroche, L. Macromol. Symp. 1995, 51. (d) Cascone, M. G.; Laus, M.; Ricci, D.; Sbarbati Del Guerra, R. J. Mater. Sci.: Mater. Med. 1995, 6, 71. (e) Bellamkonda, R.; Ranieri, J. P.; Bouche, N.; Aebischer, P. J. Biomed. Mater. Res. 1995, 29, 663. (f) Woerly, S. Biomaterials 1993, 14 (14), 1056. (g) Ansell, C. W. G. Macromol. Rep. 1995, A32 (Suppl. 5 & 6), 733.
8. For selected examples of applications, see: (a) Peppas, N. A.; Yang, W.-H. M. Contact Lens 1981, 7 (4), 300. (b) Ambrosio, L.; Netti, P. A.; Iannace, S.; Huang, S. J.; Nicolais, L. J. Mater. Sci: Mater. Med. 1996, 7, 251. (c) Laroche, L. Macromol. Symp. 1995, 51. (d) Cascone, M. G.; Laus, M.; Ricci, D.; Sbarbati Del Guerra, R. J. Mater. Sci.: Mater. Med. 1995, 6, 71. (e) Bellamkonda, R.; Ranieri, J. P.; Bouche, N.; Aebischer, P. J. Biomed. Mater. Res. 1995, 29, 663. (f) Woerly, S. Biomaterials 1993, 14 (14), 1056. (g) Ansell, C. W. G. Macromol. Rep. 1995, A32 (Suppl. 5 & 6), 733.
9. For selected examples of applications, see: (a) Peppas, N. A.; Yang, W.-H. M. Contact Lens 1981, 7 (4), 300. (b) Ambrosio, L.; Netti, P. A.; Iannace, S.; Huang, S. J.; Nicolais, L. J. Mater. Sci: Mater. Med. 1996, 7, 251. (c) Laroche, L. Macromol. Symp. 1995, 51. (d) Cascone, M. G.; Laus, M.; Ricci, D.; Sbarbati Del Guerra, R. J. Mater. Sci.: Mater. Med. 1995, 6, 71. (e) Bellamkonda, R.; Ranieri, J. P.; Bouche, N.; Aebischer, P. J. Biomed. Mater. Res. 1995, 29, 663. (f) Woerly, S. Biomaterials 1993, 14 (14), 1056. (g) Ansell, C. W. G. Macromol. Rep. 1995, A32 (Suppl. 5 & 6), 733.
10. For selected examples of applications, see: (a) Peppas, N. A.; Yang, W.-H. M. Contact Lens 1981, 7 (4), 300. (b) Ambrosio, L.; Netti, P. A.; Iannace, S.; Huang, S. J.; Nicolais, L. J. Mater. Sci: Mater. Med. 1996, 7, 251. (c) Laroche, L. Macromol. Symp. 1995, 51. (d) Cascone, M. G.; Laus, M.; Ricci, D.; Sbarbati Del Guerra, R. J. Mater. Sci.: Mater. Med. 1995, 6, 71. (e) Bellamkonda, R.; Ranieri, J. P.; Bouche, N.; Aebischer, P. J. Biomed. Mater. Res. 1995, 29, 663. (f) Woerly, S. Biomaterials 1993, 14 (14), 1056. (g) Ansell, C. W. G. Macromol. Rep. 1995, A32 (Suppl. 5 & 6), 733.
11. For various examples see: (a) San Román, J.; Levenfeld, B. Macromolecules 1991, 24, 6083. (b) Smetana, K., Jr. Biomaterials 1993, 14 (14), 1046. (c) Koul, V.; Ansari, S.; Sharma, K.; Anand, S.; Guha, S. K. J. Mater. Sci.: Mater. Med. 1995, 6, 192. (d) Gebelein, C. G.; Carraher, C. E., Jr., Eds., Polymeric Materials in Medication; Plenum Press: New York and London, 1985. (e) Chiellini, E.; Giusti, P. Polymer Science and Technology: Polymers in Medicine Biomedical and Pharmacological Applications; Plenum Press: New York and London, 1983; Vol. 23. (f) Chiellini, E.; Giusti, P.; Migliaresi, C.; Nicolais, L. Polymer Science and Technology: Polymers in Medicine II Biomedical and Pharmaceutical Applications; Plenum Press: New York and London, 1986; Vol. 34. (g) Migliaresi, C.; Nicolais, L.; Guisti, P.; Chiellini, E. Progress in Biomedical Engineering: Polymers in Medicine III; Elsevier:Amsterdam, Oxford, England, New York, Tokyo, 1988; Vol. 5.
12. For various examples see: (a) San Román, J.; Levenfeld, B. Macromolecules 1991, 24, 6083. (b) Smetana, K., Jr. Biomaterials 1993, 14 (14), 1046. (c) Koul, V.; Ansari, S.; Sharma, K.; Anand, S.; Guha, S. K. J. Mater. Sci.: Mater. Med. 1995, 6, 192. (d) Gebelein, C. G.; Carraher, C. E., Jr., Eds., Polymeric Materials in Medication; Plenum Press: New York and London, 1985. (e) Chiellini, E.; Giusti, P. Polymer Science and Technology: Polymers in Medicine Biomedical and Pharmacological Applications; Plenum Press: New York and London, 1983; Vol. 23. (f) Chiellini, E.; Giusti, P.; Migliaresi, C.; Nicolais, L. Polymer Science and Technology: Polymers in Medicine II Biomedical and Pharmaceutical Applications; Plenum Press: New York and London, 1986; Vol. 34. (g) Migliaresi, C.; Nicolais, L.; Guisti, P.; Chiellini, E. Progress in Biomedical Engineering: Polymers in Medicine III; Elsevier:Amsterdam, Oxford, England, New York, Tokyo, 1988; Vol. 5.
13. For various examples see: (a) San Román, J.; Levenfeld, B. Macromolecules 1991, 24, 6083. (b) Smetana, K., Jr. Biomaterials 1993, 14 (14), 1046. (c) Koul, V.; Ansari, S.; Sharma, K.; Anand, S.; Guha, S. K. J. Mater. Sci.: Mater. Med. 1995, 6, 192. (d) Gebelein, C. G.; Carraher, C. E., Jr., Eds., Polymeric Materials in Medication; Plenum Press: New York and London, 1985. (e) Chiellini, E.; Giusti, P. Polymer Science and Technology: Polymers in Medicine Biomedical and Pharmacological Applications; Plenum Press: New York and London, 1983; Vol. 23. (f) Chiellini, E.; Giusti, P.; Migliaresi, C.; Nicolais, L. Polymer Science and Technology: Polymers in Medicine II Biomedical and Pharmaceutical Applications; Plenum Press: New York and London, 1986; Vol. 34. (g) Migliaresi, C.; Nicolais, L.; Guisti, P.; Chiellini, E. Progress in Biomedical Engineering: Polymers in Medicine III; Elsevier:Amsterdam, Oxford, England, New York, Tokyo, 1988; Vol. 5.
14. For various examples see: (a) San Román, J.; Levenfeld, B. Macromolecules 1991, 24, 6083. (b) Smetana, K., Jr. Biomaterials 1993, 14 (14), 1046. (c) Koul, V.; Ansari, S.; Sharma, K.; Anand, S.; Guha, S. K. J. Mater. Sci.: Mater. Med. 1995, 6, 192. (d) Gebelein, C. G.; Carraher, C. E., Jr., Eds., Polymeric Materials in Medication; Plenum Press: New York and London, 1985. (e) Chiellini, E.; Giusti, P. Polymer Science and Technology: Polymers in Medicine Biomedical and Pharmacological Applications; Plenum Press: New York and London, 1983; Vol. 23. (f) Chiellini, E.; Giusti, P.; Migliaresi, C.; Nicolais, L. Polymer Science and Technology: Polymers in Medicine II Biomedical and Pharmaceutical Applications; Plenum Press: New York and London, 1986; Vol. 34. (g) Migliaresi, C.; Nicolais, L.; Guisti, P.; Chiellini, E. Progress in Biomedical Engineering: Polymers in Medicine III; Elsevier:Amsterdam, Oxford, England, New York, Tokyo, 1988; Vol. 5.
15. For various examples see: (a) San Román, J.; Levenfeld, B. Macromolecules 1991, 24, 6083. (b) Smetana, K., Jr. Biomaterials 1993, 14 (14), 1046. (c) Koul, V.; Ansari, S.; Sharma, K.; Anand, S.; Guha, S. K. J. Mater. Sci.: Mater. Med. 1995, 6, 192. (d) Gebelein, C. G.; Carraher, C. E., Jr., Eds., Polymeric Materials in Medication; Plenum Press: New York and London, 1985. (e) Chiellini, E.; Giusti, P. Polymer Science and Technology: Polymers in Medicine Biomedical and Pharmacological Applications; Plenum Press: New York and London, 1983; Vol. 23. (f) Chiellini, E.; Giusti, P.; Migliaresi, C.; Nicolais, L. Polymer Science and Technology: Polymers in Medicine II Biomedical and Pharmaceutical Applications; Plenum Press: New York and London, 1986; Vol. 34. (g) Migliaresi, C.; Nicolais, L.; Guisti, P.; Chiellini, E. Progress in Biomedical Engineering: Polymers in Medicine III; Elsevier:Amsterdam, Oxford, England, New York, Tokyo, 1988; Vol. 5.
16. For various examples see: (a) San Román, J.; Levenfeld, B. Macromolecules 1991, 24, 6083. (b) Smetana, K., Jr. Biomaterials 1993, 14 (14), 1046. (c) Koul, V.; Ansari, S.; Sharma, K.; Anand, S.; Guha, S. K. J. Mater. Sci.: Mater. Med. 1995, 6, 192. (d) Gebelein, C. G.; Carraher, C. E., Jr., Eds., Polymeric Materials in Medication; Plenum Press: New York and London, 1985. (e) Chiellini, E.; Giusti, P. Polymer Science and Technology: Polymers in Medicine Biomedical and Pharmacological Applications; Plenum Press: New York and London, 1983; Vol. 23. (f) Chiellini, E.; Giusti, P.; Migliaresi, C.; Nicolais, L. Polymer Science and Technology: Polymers in Medicine II Biomedical and Pharmaceutical Applications; Plenum Press: New York and London, 1986; Vol. 34. (g) Migliaresi, C.; Nicolais, L.; Guisti, P.; Chiellini, E. Progress in Biomedical Engineering: Polymers in Medicine III; Elsevier:Amsterdam, Oxford, England, New York, Tokyo, 1988; Vol. 5.
17. For various examples see: (a) San Román, J.; Levenfeld, B. Macromolecules 1991, 24, 6083. (b) Smetana, K., Jr. Biomaterials 1993, 14 (14), 1046. (c) Koul, V.; Ansari, S.; Sharma, K.; Anand, S.; Guha, S. K. J. Mater. Sci.: Mater. Med. 1995, 6, 192. (d) Gebelein, C. G.; Carraher, C. E., Jr., Eds., Polymeric Materials in Medication; Plenum Press: New York and London, 1985. (e) Chiellini, E.; Giusti, P. Polymer Science and Technology: Polymers in Medicine Biomedical and Pharmacological Applications; Plenum Press: New York and London, 1983; Vol. 23. (f) Chiellini, E.; Giusti, P.; Migliaresi, C.; Nicolais, L. Polymer Science and Technology: Polymers in Medicine II Biomedical and Pharmaceutical Applications; Plenum Press: New York and London, 1986; Vol. 34. (g) Migliaresi, C.; Nicolais, L.; Guisti, P.; Chiellini, E. Progress in Biomedical Engineering: Polymers in Medicine III; Elsevier:Amsterdam, Oxford, England, New York, Tokyo, 1988; Vol. 5.
18. Grundy, S. M. In Pharmacological Control of Hyperlipidaemia; Fears, R., Ed.; J. R. Prous Science Publishers, S.A.: Barcelona, Spain, 1986; pp 3-19.
19. Hunninghake, D. B. J. Drug Dev. 1990, 3 (Suppl. 1), 205.
20. Benson, G. M.; Haynes, C.; Blanchard, S.; Ellis, D. J. Pharm. Sci. 1993, 82 (1), 80.
21. Ast, M.; Frishman, W. H. J. Clin. Pharmacol. 1990, 30, 99.
22. For a theoretical discussion, see: Theodoropoulos, A. G.: Bouranis, D. L.; Vlyssides, A. G.; Kotsibou, E. D. Macromol. Rep. 1996, A33 (Suppl. 5 & 6), 281.
23. Cawse, J. L.; Stanford, J. L.; Still, R. H. Macromol. Chem. 1984, 185, 697.
24. Von Hipple, M. J. Mol. Biol. 1974, 86 , 469.
25. For methodology directly related to these sequestrants See also: (a)Figuly, G. D. (E. I. DuPont de Nemours & Co.) U. S. Patent 5,633,344, 1997. (b) Royce, S. D.; Figuly, G. D.; Khasat, N. P.; Matos, J. R. (DuPont Merck Pharmaceutical Co. and E. I. DuPont de Nemours & Co.) U. S. Patent 5,556,619, 1996. (c) Shimshick, E. J.; Figuly, G. D.; Grimminger, L. C.; Hainer, J. W.; Jensen, J. H.; Leipold, R. J.; Royce, S. D.; Gillies, P. J. Drug Dev. Res., in press.
26. For methodology directly related to these sequestrants See also: (a)Figuly, G. D. (E. I. DuPont de Nemours & Co.) U. S. Patent 5,633,344, 1997. (b) Royce, S. D.; Figuly, G. D.; Khasat, N. P.; Matos, J. R. (DuPont Merck Pharmaceutical Co. and E. I. DuPont de Nemours & Co.) U. S. Patent 5,556,619, 1996. (c) Shimshick, E. J.; Figuly, G. D.; Grimminger, L. C.; Hainer, J. W.; Jensen, J. H.; Leipold, R. J.; Royce, S. D.; Gillies, P. J. Drug Dev. Res., in press.
27. For methodology directly related to these sequestrants See also: (a)Figuly, G. D. (E. I. DuPont de Nemours & Co.) U. S. Patent 5,633,344, 1997. (b) Royce, S. D.; Figuly, G. D.; Khasat, N. P.; Matos, J. R. (DuPont Merck Pharmaceutical Co. and E. I. DuPont de Nemours & Co.) U. S. Patent 5,556,619, 1996. (c) Shimshick, E. J.; Figuly, G. D.; Grimminger, L. C.; Hainer, J. W.; Jensen, J. H.; Leipold, R. J.; Royce, S. D.; Gillies, P. J. Drug Dev. Res., in press.
28. Danielsson, H.; Sjîvall, J.; Eds. Sterols and Bile Acids; Elsevier: Amsterdam, New York, Oxford, England, 1985.
29. For a more comprehensive review, see: (a) Nair, P. P.; Kritchevsky, D.; Eds. The Bile Acids Volume 1: Chemistry; Plenum Press: New York, 1971 (b) Ibid. Volume 2: Physiology and Metabolism; 1973
30. For a more comprehensive review, see: (a) Nair, P. P.; Kritchevsky, D.; Eds. The Bile Acids Volume 1: Chemistry; Plenum Press: New York, 1971 (b) Ibid. Volume 2: Physiology and Metabolism; 1973
31. (c)Ibid. Volume 3: Pathophysiology: 1976.
32. For examples of synthetic methodologies and polymers, see: (a) Kuron, G. W.; Grier, N.; Huff, J. W. Atherosclerosis 1980, 37, 353. (b) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,206,295, 1980. (c) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,205,064, 1980. (d) Shen, T.-Y.; Wagner, A. F. (Merck & Co.) U. S. Patent 4,071,478, 1978. (e) Wolf, F. J.; Tennent, D. M. (Merck & Co.) U. S. Patent 3,308,020, 1967.
33. For examples of synthetic methodologies and polymers, see: (a) Kuron, G. W.; Grier, N.; Huff, J. W. Atherosclerosis 1980, 37, 353. (b) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,206,295, 1980. (c) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,205,064, 1980. (d) Shen, T.-Y.; Wagner, A. F. (Merck & Co.) U. S. Patent 4,071,478, 1978. (e) Wolf, F. J.; Tennent, D. M. (Merck & Co.) U. S. Patent 3,308,020, 1967.
34. For examples of synthetic methodologies and polymers, see: (a) Kuron, G. W.; Grier, N.; Huff, J. W. Atherosclerosis 1980, 37, 353. (b) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,206,295, 1980. (c) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,205,064, 1980. (d) Shen, T.-Y.; Wagner, A. F. (Merck & Co.) U. S. Patent 4,071,478, 1978. (e) Wolf, F. J.; Tennent, D. M. (Merck & Co.) U. S. Patent 3,308,020, 1967.
35. For examples of synthetic methodologies and polymers, see: (a) Kuron, G. W.; Grier, N.; Huff, J. W. Atherosclerosis 1980, 37, 353. (b) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,206,295, 1980. (c) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,205,064, 1980. (d) Shen, T.-Y.; Wagner, A. F. (Merck & Co.) U. S. Patent 4,071,478, 1978. (e) Wolf, F. J.; Tennent, D. M. (Merck & Co.) U. S. Patent 3,308,020, 1967.
36. For examples of synthetic methodologies and polymers, see: (a) Kuron, G. W.; Grier, N.; Huff, J. W. Atherosclerosis 1980, 37, 353. (b) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,206,295, 1980. (c) Wagner, A. F.; Grier, N.; Shen, T.-Y. (Merck & Co.) U. S. Patent 4,205,064, 1980. (d) Shen, T.-Y.; Wagner, A. F. (Merck & Co.) U. S. Patent 4,071,478, 1978. (e) Wolf, F. J.; Tennent, D. M. (Merck & Co.) U. S. Patent 3,308,020, 1967.
37. Flory, P. J. Principles of Polymer Chemistry; Cornell University Press: Ithaca, NY, and London, 1953; Chapter IX.
38. Gillies, P. J.; Billheimer, J. T.; Blackston, V. A.; Cromley, D. A.; Figuly, G. D.; Fischer, R. T.; Germain, S. J.; Godonis, H. E.; Gorko, M. A.; Grimminger, L. C.; Harvey, S. J.; Jensen J. H.; Kieras, C. J.; Royce, S. D.; Pautler, H. C.; Shimshick, E. J.; Stevenson, R. C.; Hainer, J. W. Drug Dev. Res., in press.
39. Hainer, J. W.; Hunninghake, D. B.; Benedek, I. H.; Broyles, F. E.; Garner, D. M.; Jenkins, R. M.; McGinn, A.; Pieniaszek, H. J., Jr.; London, E.; Gillies, P. J. Drug Dev. Res., in press.
40. Flory, P. J.; Rehner, J., Jr. J. Chem. Phys. 1943, 11, 521.
41. For practical examples see also: (a) Bueche, A. M. J. Polym. Sci. 1955, 15, 97 and 105. (b) Barrell, E. M., II; Flandera, M. A.; Logan, J. A. Thermochim. Acta 1973, 5, 413. (c) Prime, R. B. Thermochim Acta 1978, 26, 165.
42. For practical examples see also: (a) Bueche, A. M. J. Polym. Sci. 1955, 15, 97 and 105. (b) Barrell, E. M., II; Flandera, M. A.; Logan, J. A. Thermochim. Acta 1973, 5, 413. (c) Prime, R. B. Thermochim Acta 1978, 26, 165.
43. For practical examples see also: (a) Bueche, A. M. J. Polym. Sci. 1955, 15, 97 and 105. (b) Barrell, E. M., II; Flandera, M. A.; Logan, J. A. Thermochim. Acta 1973, 5, 413. (c) Prime, R. B. Thermochim Acta 1978, 26, 165.