[11C]S21007, a putative partial agonist for 5-HT3 receptors PET studies. Rat and primate in vivo biological evaluation

Life Sciences

Volumn 62, Issue 2, 1997, Pages 115-129

  Besret, L ^a   Dauphin, F ^a   Guillouet, S ^a   Dhilly, M ^a   Gourand, F ^a   Blaizot, X ^a   Young, A R ^a   Petit Taboue M C ^a   Mickala, P ^a   Barbelivien, A ^a   Rault, S ^a   Barre L ^a   Baron, J C ^a  

^a UNIVERSITÉ DE CAEN   (France)

Author keywords

5 HT3 receptors; Baboon; In vivo binding; Pharmacokinetics; Phosphorimaging system; Positron emission topography; Rat; Serotonergic receptors

Indexed keywords

S 21007; SEROTONIN; SEROTONIN 3 AGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN RECEPTOR; TROPISETRON; UNCLASSIFIED DRUG; ZACOPRIDE; CARBON; PIPERAZINE DERIVATIVE; PYRAZINE DERIVATIVE; SEROTONIN AGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA POSTREMA; ARTICLE; AUTORADIOGRAPHY; BABOON; DRUG METABOLISM; DRUG PENETRATION; DRUG RECEPTOR BINDING; DRUG TISSUE LEVEL; GUINEA PIG; HIPPOCAMPUS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PHARMACOKINETICS; POSITRON EMISSION TOMOGRAPHY; RAT; RECEPTOR AFFINITY; ANIMAL; BLOOD; BRAIN; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG EFFECT; MALE; METABOLISM; PAPIO; RADIOASSAY; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ANIMALS; AUTORADIOGRAPHY; BRAIN; CARBON RADIOISOTOPES; MALE; PAPIO; PIPERAZINES; PYRAZINES; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN AGONISTS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0031555388     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(97)01058-8     Document Type: Article

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