In vitro phosphorylation of medial vestibular nucleus and prepositus hypoglossi proteins during behavioural recovery from unilateral vestibular deafferentation in the guinea pig

Brain Research

Volumn 778, Issue 1, 1997, Pages 166-177

  Sansom, Andrew J ^a,b   Brent, Vicki A ^c   Jarvie, Paula E ^c   Darlington, Cynthia L ^a   Smith, Paul F ^b   Laverty, Richard ^b   Rostas, John A P ^c  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Guinea pig; Medial vestibular nuclei; Neural plasticity; Protein kinase C; Protein phosphorylation; Vestibular compensation

Indexed keywords

PROTEIN KINASE C;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DEAFFERENTATION; ENZYME ACTIVITY; GUINEA PIG; LABYRINTHECTOMY; NERVE CELL PLASTICITY; NERVE TRACT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; VESTIBULAR NUCLEUS;

AFFERENT PATHWAYS; ANIMALS; BEHAVIOR, ANIMAL; DENERVATION; ENZYME ACTIVATION; FEMALE; FUNCTIONAL LATERALITY; GUINEA PIGS; HYPOGLOSSAL NERVE; MALE; PHOSPHORYLATION; POSTOPERATIVE PERIOD; PROTEIN KINASES; STIMULATION, CHEMICAL; VESTIBULAR NUCLEI;

EID: 0031555364     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01059-7     Document Type: Article

References (51)

1. Albert K.A., Wu W.C., Nairn A.C., Greengard P. Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation. Proc. Natl. Acad. Sci. USA. 81:1984;3622-3625.
2. Anderson L.G., Zhao D., Dell K.R., Severson D.L., Auer R.N. Brain protein kinase C assay using MARCKS substrate reveals no translocation due to profound insulin-induced hypoglycaemia. Brain Res. 606:1993;187-194.
3. Balaban C.D., Goto M.M., Romero G.G. Transient changes in cerebellar protein kinase C expression after unilateral labyrinthectomy. J. Vest. Res. Suppl. 6(4S):1996;S11.
4. Blackshear P.J. The MARCKS family of cellular protein kinase C substrates. J. Biol. Chem. 268(3):1993;1501-1504.
5. Cirelli C., Pompeiano M., D'Ascanio P., Arrighi P., Pompeiano O. c-fos expression in the rat brain after unilateral labyrinthectomy and its relation to the uncompensated and compensated stages. Neurosci. 70(2):1996;515-546.
6. Coggins P.J., Zwiers H. B-50 (GAP-43): Biochemistry and functional neurochemistry of a neuron-specific phosphoprotein. J. Neurochem. 56:1991;1095-1106.
7. Curthoys I.S., Smith P.F., Darlington C.L., Postural compensation in the guinea pig following unilateral labyrinthectomy, in: O. Pompeiano, J.H.J. Allum (Eds.), Progress in Brain Research, vol. 76, Elsevier, Amsterdam, 1988, pp. 375-384.
8. Curthoys I.S., Halmagyi G.M. Vestibular compensation: a review of the ocular motor, neural, and clinical consequences of unilateral vestibular loss. J. Vest. Res. 5(2):1995;67-107.
9. Darlington C.L., Smith P.F. The recovery of static vestibular function following peripheral vestibular lesions in mammals: The intrinsic mechanism hypothesis. J. Vest. Res. 6:1996;185-201.
10. Darlington C.L., Lawlor P., Smith P.F., Dragunow M. Temporal relationship between the expression of Fos, Jun and Krox-24 in the guinea pig vestibular nuclei during the development of vestibular compensation for unilateral vestibular deafferentation. Brain Res. 735:1996;173-176.
11. Dieringer N. `Vestibular compensation': neural plasticity and its relations to functional recovery after labyrinthine lesions in frogs and other vertebrates. Prog. Neurobiol. 46:1995;97-129.
12. de Waele C., Vibert N., Baudrimont M., Vidal P.-P. NMDA receptors contribute to the resting discharge of vestibular neurons in the normal and labyrinthectomized guinea pig. Exp. Brain Res. 81:1990;125-133.
13. de Waele C., Abitbol M., Chat M., Menini C., Mallet J., Vidal P.-P. Distribution of glutamatergic receptors and GAD mRNA-containing neurons in the vestibular nuclei of normal and hemilabyrinthectomized rats. Eur. J. Neurosci. 6:1993;565-576.
14. Elkabes S., Cherry J.A., Schoups A.A., Black I.B. Regulation of protein kinase C activity by sensory deprivation in the olfactory and visual systems. J. Neurochem. 60:1993;1835-1842.
15. Flohr H., Bienhold H., W. Ablen, Macskovics I., Concepts of vestibular compensation, in Lesion-induced Neuronal Plasticity in Sensorimotor Systems, in: H. Flohr, W. Precht (Eds.), Springer-Verlag, Berlin, 1981, pp. 153-172.
16. H. Flohr, U. Luneburg, C. Richter-Landsberg, ACTH/MSH-like neuropeptides and lesion-induced plastic processes, in: E. Keller, D.S. Zee (Eds.), Adaptive Processes in Visual and Oculomotor Systems, Pergamon Press, Oxford, 1986, pp. 409-416.
17. Flohr H., Luneburg U. Role of NMDA receptors in lesion-induced plasticity. Arch. Ital. Biol. 131:1993;173-190.
18. Gispen W.H., Routtenberg A., Protein kinase C and its brain substrates, Prog. Brain Res. 89 (1991).
19. Gilchrist D.P.D., Darlington C.L., Smith P.F. A dose-response analysis of the beneficial effects of the ACTH-(4-9) analogue, Org 2766, on behavioural recovery following unilateral labyrinthectomy in guinea pig. Br. J. Pharmacol. 111:1994;358-364.
20. Goto M.M., Romero G.G., Balaban C.D. Transient changes in flocculonodular lobe protein kinase C expression during vestibular compensation. J. Neurosci. 17(11):1997;4367-4381.
21. Hartwig J.H., Thelen M., Rosen A., Janmey P.A., Nairn A.C., Aderem A. MARCKS is an actin filament cross-linking protein regulated by protein kinase C and calcium-calmodulin. Nature. 356:1992;618-622.
22. Hughes P., Dragunow M. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol. Rev. 47(1):1995;133-178.
23. Janssen U., Richter-Landsberg C., Flohr H. Vestibular compensation affects endogenous phosphorylation of frog brain proteins. J. Neurochem. 58(1):1992;65-71.
24. Janssen U., Richter-Landsberg C., Oestreicher A.B., De Graaf P.N.E., Gispen W.H., Flohr H. Identification of a B-50-like protein in frog brain synaptosomes. Brain Res. 570:1992;21-26.
25. Jeitner T.M., Jarvie P.E., Costa M., Rostas J.A.P., Dunkley P.R. Protein phosphorylation in guinea pig myenteric ganglia and brain: presence of calmodulin kinase II, protein kinase C and cyclic AMP kinase and characterisation of major phosphoproteins. Neurosci. 40(2):1991;555-569.
26. Kaufman G.D., Anderson J.H., Beitz A.J. Brainstem Fos expression following acute unilateral labyrinthectomy in the rat. NeuroRep. 3:1992;829-832.
27. Kitahara T., Saika T., Takeda N., Kiyama H., Kubo T. Changes in Fos and Jun expression in the rat brainstem in the process of vestibular compensation. Acta Otolaryngol. (Stockholm) Suppl. 520:1995;401-404.
28. Kitahara T., Takeda N., Saika T., Kubo T., Kiyama H. Effects of MK-801 on Fos expression in the rat brainstem after unilateral labyrinthectomy. Brain Res. 700:1995;182-190.
29. 3H]dizocilpine maleate binding in rat vestibular nuclear complex after unilateral deafferentation, with comparison to cochlear nucleus. Neurosci. 77(2):1997;473-484.
30. Marascuilo L.A., Serlin R.C., Statistical Methods for the Social and Behavioural Sciences, Freeman and Co, New York, 1988, pp. 501-503.
31. McNamara R.K., Lenox R.H. Comparative distribution of myristoylated alanine-rich C kinase substrate (MARCKS) and F1/GAP43 gene expression in the adult rat brain. J. Comp. Neurol. 379:1997;48-71.
32. Newlands S.D., Perachio A.A. Compensation of horizontal canal related activity in the medial vestibular nucleus following unilateral labyrinth ablation in the decerebrate gerbil. 1. Type I neurons. Exp. Brain Res. 82:1990;359-372.
33. Ouimet C.C., Wang J.K.T., Walaas I.S., Albert K.A., Greengard P. Localisation of the MARCKS (87 kDa) protein, a major specific substrate for protein kinase C, in rat brain. J. Neurosci. 10(5):1990;1683-1698.
34. Pettorossi V.E., Della Torre G., Grassi S., Zampolini M., Capocchi G., Errico P. Role of NMDA receptors in the compensation of ocular nystagmus induced by hemilabyrinthectomy in the guinea pig. Arch. Ital. Biol. 130:1992;303-313.
35. Ris L., de Waele C., Serafin M., Vidal P.-P., Godaux E. Neuronal activity in the ipsilateral vestibular nucleus following unilateral labyrinthectomy in the alert guinea pig. J. Neurophysiol. 74(5):1995;2087-2099.
36. Robinson P.J. The role of protein kinase C and its neuronal substrates dephosphin, B-50, and MARCKS in neurotransmitter release. Mol. Neurobiol. 5:1992;87-130.
37. Sans N., Moniot B., Raymond J. Effects of a unilateral labyrinthectomy on NMDA subunits mRNA expression in the vestibular nuclei of the guinea pig. Eur. J. Neurosci., Suppl. 8:1995;. abstract 70.17.
38. Sansom A.J., Darlington C.L., Smith P.F. Intraventricular injection of an NMDA antagonist disrupts vestibular compensation. Neuropharmacol. 29:1990;83-84.
39. Sansom A.J., Darlington C.L., Smith P.F., Gilchrist D.P.D., Keenan C.J., Kenyon R. Injections of calmidazolium chloride into the ipsilateral medial vestibular nucleus or IVth ventricle reduce spontaneous ocular nystagmus following unilateral labyrinthectomy in guinea pig. Exp. Brain Res. 93:1993;271-278.
40. Sansom A.J., Smith P.F., Darlington C.L. Fentazin anaesthesia for labyrinthine surgery in guinea pigs. J. Vest. Res. 6(1):1996;49-52.
41. Smith P.F., Curthoys I.S. Neuronal activity in the ipsilateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy. Brain Res. 444:1988;308-319.
42. Smith P.F., Curthoys I.S. Mechanisms of recovery following unilateral labyrinthectomy: a review. Brain Res. Rev. 14:1989;155-180.
43. Smith P.F., Darlington C.L. The NMDA antagonists MK-801 and CPP disrupt compensation for unilateral labyrinthectomy in the guinea pig. Neurosci. Lett. 94:1988;309-313.
44. Smith P.F., Darlington C.L. Neurochemical mechanisms of recovery from peripheral vestibular lesions (vestibular compensation). Brain Res. Rev. 16:1991;117-133.
45. Stumpo D.J., Bock C.B., Tuttle J.S., Blackshear P.J. MARCKS deficiency in mice leads to abnormal brain development and prenatal death. Proc. Natl. Acad. Sci. USA. 92:1995;944-948.
46. Uemura T., Cohen B. Effects of vestibular lesions on vestibulo-ocular reflexes and posture in monkeys. Acta Oto-Laryngol. (Stockholm), Suppl. 315:1973;1-71.
47. Waehneldt T.V., Malotka N.J., Karin N.J., Matthieu J.-M. Phylogenetic examination of vertebrate central nervous system myelin proteins by electro-immunoblotting. Neurosci. Lett. 57:1985;97-102.
48. Walaas S.I., Nairn A.C., Greengard P. Regional distribution of calcium and cyclic AMP-regulated protein phosphorylation systems. in mammalian brain. II. Soluble systems. J. Neurosci. 3:1983;302-311.
49. Walaas S.I., Greengard P. Protein phosphorylation and neuronal function. Pharmacol. Rev. 43(3):1991;299-349.
50. Wiklund P., Ekstrom Per A.R., Edbladh M., Tonge D., Edstrom A. Protein kinase C and mouse sciatic nerve regeneration. Brain Res. 715:1996;145-154.
51. Wilson V.J., Melvill-Jones G., Mammalian Vestibular Physiology, Plenum, New York, 1979.