Phosphatidylserine synthase I and II of mammalian cells

Biochimica et Biophysica Acta - Lipids and Lipid Metabolism

Volumn 1348, Issue 1-2, 1997, Pages 151-156

  Kuge, Osamu ^a   Nishijima, Masahiro ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Mammalian cell; Phosphatidylcholine synthase I; Phosphatidylcholine synthase II

Indexed keywords

ISOENZYME; PHOSPHATIDYLSERINE SYNTHASE;

ANIMAL CELL; CELL MUTANT; CHO CELL; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; MAMMAL CELL; MOLECULAR CLONING; MUTANT; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; ISOENZYMES; MOLECULAR SEQUENCE DATA; NITROGENOUS GROUP TRANSFERASES; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 0031553017     PISSN: 00052760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2760(97)00137-9     Document Type: Review

References (21)

1. Hübscher G., Dils R.R., Pover W.F.R. Studies on the biosynthesis of phosphatidylserine. Biochim Biophys. Acta. 36:1959;518-528.
2. Dils R.R., Hübscher G. Metabolism of phospholipids III. The effect of calcium ions on the incorporation of labelled choline into rat-liver microsomes. Biochim. Biophys. Acta. 46:1961;505-513.
3. Hübscher G. Metabolism of phospholipids VI. The effect of metal ions on the incorporation of L-serine into phosphatidylserine. Biochim. Biophys. Acta. 57:1962;555-561.
4. Borkenhagen J.D., Kennedy E.P., Fielding L. Enzymatic formation and decarboxylation of phosphatidylserine. J. Biol. Chem. 236:1961;PC28-PC29.
5. Kanfer J.N. The base exchange enzymes and phospholipipase D of mammalian tissue. Can. J. Biochem. 58:1980;1370-1380.
6. Marggraf W.D., Anderer F.A. Alternative pathways in the biosynthesis of phosphatidylserine in mouse cells. Hoppe-Seyler's Z. Physiol. Chem. 335:1974;1299-1304.
7. Jelsema C.L., Morré D.J. Distribution of phospholipid biosynthetic enzymes among cell components of rat liver. J. Biol. Chem. 253:1978;7960-7971.
8. Vance J.E. Phospholipid synthesis in a membrane fraction associated with mitochondria. J. Biol. Chem. 265:1990;7248-7256.
9. Saito K., Kuge O., Akamatsu Y., Nishijima M. Immunochemical identification of the pssA gene product as phosphatidylserine synthase I of Chinese hamster ovary cells. FEBS Lett. 395:1996;262-266.
10. Shiao Y.-J., Lupo G., Vance J.E. Evidence that phosphatidylserine is imported into mitochondria via a mitochondria-associated membrane and that the majority of mitochondrial phosphatidylethanolamine is derived from decarboxylation of phosphatidylserine. J. Biol. Chem. 279:1995;11190-11198.
11. Kuge O., Nishijima M., Akamatsu Y. Phosphatidylserine biosynthesis in cultured Chinese hamster ovary cells II. Isolation and characterization of phosphatidylserine auxotrophs. J. Biol. Chem. 261:1986;5790-5794.
12. Kuge O., Nishijima M., Akamatsu Y. Isolation of a somatic-cell mutant defective in phosphatidylserine biosynthesis. Proc. Natl. Acad. Sci. USA. 82:1985;1926-1930.
13. Voelker D.R., Frazier J.L. Isolation and characterization of a Chinese hamster ovary cell line requiring ethanolamine or phosphatidylserine for growth and exhibiting defective phosphatidylserine synthase activity. J. Biol. Chem. 261:1986;1002-1008.
14. Kuge O., Nishijima M., Akamatsu Y. A Chinese hamster cDNA encoding a protein essential for phosphatidylserine synthase I activity. J. Biol. Chem. 266:1991;24184-24189.
15. O. Kuge, K. Saito, M. Nishijima, Cloning of a Chinese hamster ovary (CHO) cDNA encoding phosphatidylserine synthase (PSS) II, overexpression of which suppresses the phosphatidylserine biosynthetic defect of a PSS I-lacking mutant of CHO-K1 cells, J. Biol. Chem., 272 (1997) 19133-19139.
16. Kuge O., Nishijima M., Akamatsu Y. Phosphatidylserine biosynthesis in cultured Chinese hamster ovary cells III. Genetic evidence for utilization of phosphatidylcholine and phosphatidylethanolamine as precursors. J. Biol. Chem. 261:1986;5795-5798.
17. Hasegawa K., Kuge O., Nishijima M., Akamatsu Y. Isolation and characterization of a Chinese hamster ovary cell mutant with altered regulation of phosphatidylserine biosynthesis. J. Biol. Chem. 264:1989;19887-19892.
18. Nishijima M., Kuge O., Akamatsu Y. Phosphatidylserine biosynthesis in cultured Chinese hamster ovary cells I. Inhibition of de novo phosphatidylserine biosynthesis by exogenous phosphatidylserine and its efficient incorporation. J. Biol. Chem. 261:1986;5784-5786.
19. Suzuki Y.T., Kanfer J.N. Purification and properties of an ethanolamine-serine base exchange enzyme of rat brain microsomes. J. Biol. Chem. 260:1985;1394-1399.
20. Schtze M.-P., Peterson P.A., Jackson M.R. An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum. EMBO J. 13:1994;1696-1705.
21. Jackson M.R., Nilsson T., Peterson P.A. Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum. EMBO J. 9:1990;3153-3162.