The 80's loop (residues 78 to 85) is important for the differential activity of retroviral proteases

Journal of Molecular Biology

Volumn 267, Issue 3, 1997, Pages 467-475

  Stebbins, Jeffrey ^a,b   Towler, Eric M ^a   Tennant, Michael G ^a   Deckman, Ingrid C ^a,c   Debouck, Christine ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c JOHNSON AND JOHNSON   (United States)

Author keywords

AIDS; Differential activity; Molecular modeling; Protein engineering; Retroviral proteases

Indexed keywords

PROTEINASE; VIRUS ENZYME;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GENETIC ENGINEERING; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; SIMIAN IMMUNODEFICIENCY VIRUS; STRUCTURE ACTIVITY RELATION;

EID: 0031552351     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.0891     Document Type: Editorial

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