Discovery of imidazo[1,2-c]pyrimidin-5(6H)-one heterosubstituted nucleoside analogues with potent activity against human hepatitis B virus in vitro

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 3, 1997, Pages 303-308

  Mansour, Tarek S ^a   Evans, Colleen A ^a   Charron, Marie ^a   Korba, Brent E ^b  

^a Shire Canada   (Canada)

^b GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; IMIDAZO[1,2 C]PYRIMIDINE DERIVATIVE; NUCLEOSIDE ANALOG; PYRIMIDINE NUCLEOSIDE; UNCLASSIFIED DRUG; ZALCITABINE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; REACTION ANALYSIS; STEREOCHEMISTRY; VIRUS REPLICATION;

EID: 0031552078     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00001-2     Document Type: Article

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