Highly enantioselective reduction of prochiral ketones with N,N-diethylaniline·borane (DEANB) in oxazaborolidine-catalyzed reductions

Tetrahedron Letters

Volumn 38, Issue 9, 1997, Pages 1523-1526

  Salunkhe, Ashok M ^a   Burkhardt, Elizabeth R ^a  

^a Callery Chemical Company   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORANE DERIVATIVE; KETONE; REDUCING AGENT;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHIRALITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; REDUCTION;

EID: 0031550862     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00128-7     Document Type: Article

References (28)

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22. 9. Addition time was 40 minutes for 8.3 mmol of acetophenone and the reaction temperature was 20 °C.
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24. 11. The compound does not react with methanol nor does it convert to HCBS when heated to 100 °C for 6 h in a sealed vessel in THF.
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