Image analysis as a new technique for the study of water uptake in tablets

S.T.P. Pharma Sciences

Volumn 7, Issue 3, 1997, Pages 117-122

  Le Neel T ^a   Morlet Renaud, C ^a   Li Part, C ^a   Gouyette, A ^a   Truchaud, A ^a   Merle, C ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

image analysis; swelling disintegration; Tablet; water uptake

Indexed keywords

DISINTEGRATING AGENT; LACTOSE; WATER;

ARTICLE; CHROMATOGRAPHY; DRUG DESIGN; DRUG FORMULATION; IMAGE ANALYSIS; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET HARDNESS; TABLET THICKNESS; VOLUMETRY; WATER TRANSPORT;

EID: 0031545628     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. DUCHENE D. La désagrégation des comprimés. Labo Pharma Probl. Techn., 32, 123-131, 1984.
2. LOWENTHAL W. Disintegration of tablets. J. Pharm. Sci., 61, 11, 1695-1711, 1972.
3. GUYOT-HERMANN A.M. and RINGARD J. Disintegration mechanisms of tablets containing starches. Hypothesis about the particle-particle repulsive force. Drug Dev. Ind. Pharm., 7, 155-177, 1981.
4. MATSUMARU H. Studies on the mechanism of tablet compression and disintegration. IV. Evolution of wetting heat and its reduction by compressional force. Yakugaku Zasshi, 79,63-64, 1959.
5. COUVREUR P., GILLARD J., VAN DEN SCHRECK H.G. and ROLAND M. Mécanisme de désintégration des comprimés à base d'amidon. J. Pharm. Belg., 29, 399-414, 1974.
6. RINGARD J. and GUYOT-HERMANN A.M. Influence de l'établissement d'un réseau hydrophile et continu d'amidon sur les propriétés des comprimés. I. Répercussion sur le temps de délitement et la dissolution des principes actifs. J. Pharm. Belg., 33, 99-110, 1978.
7. NOGAMI H., NAGAI T., FUKUOKA E. and SONOBE T. Powdered preparation : disintegration of tablets containing potato starch and microcrystalline cellulose in various concentrations. Chem. Pharm. Bull., 17, 1450-1455, 1969.
8. VAN KAMP H.V., BOLHUIS O.K., DE BOER A.H., LERK C.F. and LIE-A-HUEN L. The role of water uptake on tablet disintegration. Pharm. Acta Helv., 61, 22-29, 1986.
9. ERDOS S. and BEZEGH A. Studies on the mechanism of disintegration. Pharm. Ind., 39, 1130-1135,1977.
10. GIORDANO F., RONCHI M., CARAMELLA C., GAZ2ANIGA A., BRUNI G. and BETTINETTI G.P. Proc. 10th Pharm. Tech. Conf., 16-18 april 1991, Bologna (Italy), 1, p. 646.
11. GISSINGER D. and STAMM A. Etude des propriétés d'un nouvel agent de délitement pour comprimés : la carboxyméthylcellulose réticulée. Labo-Pharma Probl. Techn., 294,27-31, 1980.
12. LIST P.H. and MUAZZAM U.A. Swelling : the force that disintegrates. Drugs made in Germany, 22,161-170,1979.
13. COLOMBO P., CARAMELLA C., CONTE U., LA MANNA A., GUYOT-HERMANN A.M. and RINGARD J. Force de délitement des comprimés. Proc. 2nd Int. Conf. on Pharm. Tech., 3-5 June 1980, Paris, APGI Ed., Vol. Il, pp. 88-96.
14. CARAMELLAC., FERRARI F., GAZZANIGAA., CONTE U., LA MANNA A. and GEDDO M. A new computer-aided apparatus for simultaneous measurements of water uptake and swelling force in tablets. Drug Dev. Ind. Pharm., 14,15-17,2167-2177, 1988.
15. WASHINGTON C. Particle Size Analysis in Pharmaceutics and Other Industries, Theory and Practice. Ellis Norwood, Chichester, 1992, pp. 215-235.
16. MOUSSA I.S. and CARTILIER L.H. Image analysis for the study of water penetration and polymer swelling in cross-linked amylose Proc. 1 st World Meeting APGI/APV, Budapest, 9/11 May 1995, pp. 149-150.
17. LE NEEL T., CAZAUBIEL M., ESPAZE E., MERLE C. and TRUCHAUD A. Image analysis in the clinical laboratory : application of filtration cytometry to bacteriological screening of urine samples. Clin. Biochem., 29, 171-173, 1996.
18. LE NEEL T. Contribution àl'étude de la désagrégation des comprimés par analyse d'image. Ph.D. Thesis, University of Nantes, 1995.
19. OTSUKA M., KANENIWA N., KAWAKAMI K. and UMEZAWA O. Effects of tableting pressure on hydration kinetics of theophyllineanhydrate tablets -J. Pharm. Pharmacol.,43,226231, 1991.
20. SAKR A., BOSE M. and MENON A. Comparative effectiveness of super disintegrants on the characteristics of directly compressed triamterene hydrochlorothiazide tablets Pharm. Ind., 55, 953-957, 1993.
21. CARAMELLA C., GIORDANO F., FERRARI F., BERTONI M., BRUNI G., GAZZANIGA A. and BETTINETTI G.P. A new approach to the assessment of disintegrant efficiency. Proc. 1ères Rencontres Galéniques de Rabat RGR/94, 28-30 March 1994, Rabat, pp. 319-325.