메뉴 건너뛰기




Volumn 7, Issue 1, 1997, Pages 53-61

Drug delivery into the brain using implantable polymeric systems;Liberation de principes actifs dans le cerveau a partir de systemes polymeres implantables

Author keywords

Anticancer drugs; Biodegradable polymer; Chemotherapy; Drug delivery; Microspheres; Neurooncology; Neurotrophic factors; Transmitters

Indexed keywords

ANTIMITOTIC AGENT; BETHANECHOL; BRAIN DERIVED NEUROTROPHIC FACTOR; CARMUSTINE; CORTISONE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DIMETICONE; DOPAMINE; DOXORUBICIN; ETHYLENE VINYL ACETATE COPOLYMER; FLUOROURACIL; HEPARIN; INTERFERON; LEVODOPA; METHOTREXATE; MICROSPHERE; MINOCYCLINE; MITOMYCIN; MONOSIALOGANGLIOSIDE; NERVE GROWTH FACTOR; NEUROTRANSMITTER; NEUROTROPHIC FACTOR; NIMUSTINE; NORADRENALIN; PACLITAXEL; POLY(METHYL METHACRYLATE); POLYANHYDRIDE; POLYGLACTIN; POLYMER;

EID: 0031544326     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (12)

References (99)
  • 1
    • 0027050154 scopus 로고
    • Drug delivery to the central nervous system : A review
    • TAMARGO R.J. and BREM H. - Drug delivery to the central nervous system : a review. - Neurosurgery Quarterly, 2, 259-279, 1992.
    • (1992) Neurosurgery Quarterly , vol.2 , pp. 259-279
    • Tamargo, R.J.1    Brem, H.2
  • 2
    • 0018880975 scopus 로고
    • Reversible osmotic blood-brain barrier disruption in humans : Implications for the chemotherapy of malignant brain tumors
    • NEUWELT E.A., FRENKEL F.P., DIEHL J., VU L.H., RAPOPORT S. and HILL S. - Reversible osmotic blood-brain barrier disruption in humans : implications for the chemotherapy of malignant brain tumors. - Neurosurgery, 7, 44-52, 1980.
    • (1980) Neurosurgery , vol.7 , pp. 44-52
    • Neuwelt, E.A.1    Frenkel, F.P.2    Diehl, J.3    Vu, L.H.4    Rapoport, S.5    Hill, S.6
  • 3
    • 0024242598 scopus 로고
    • Use of implantable pumps for central nervous system drug infusions to treat neurological disease
    • HARBAUGH R.E., SAUNDERS R.L. and REEDER R.F. - Use of implantable pumps for central nervous system drug infusions to treat neurological disease. - Neurosurgery, 23, 693-698, 1988.
    • (1988) Neurosurgery , vol.23 , pp. 693-698
    • Harbaugh, R.E.1    Saunders, R.L.2    Reeder, R.F.3
  • 4
    • 0024317625 scopus 로고
    • Site-specific drug delivery to central nervous system : Old and new
    • HOLLISTER L.E. - Site-specific drug delivery to central nervous system : old and new. - Neurobiol. Aging, 10, 631-628, 1989.
    • (1989) Neurobiol. Aging , vol.10 , pp. 631-1628
    • Hollister, L.E.1
  • 5
    • 0029095850 scopus 로고
    • Catheter systems for intrathecal drug delivery
    • PENN R.D., YORK M.M. and PAICE J.A. - Catheter systems for intrathecal drug delivery. - J. Neurosurg., 83, 215-217, 1995.
    • (1995) J. Neurosurg. , vol.83 , pp. 215-217
    • Penn, R.D.1    York, M.M.2    Paice, J.A.3
  • 6
    • 0028911362 scopus 로고
    • Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)
    • KREUTER J., ALYAUTDIN R.N., KHARKEVICH D.A. and IVANOV A.A. - Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles). - Brain Res., 674, 171-174, 1995.
    • (1995) Brain Res. , vol.674 , pp. 171-174
    • Kreuter, J.1    Alyautdin, R.N.2    Kharkevich, D.A.3    Ivanov, A.A.4
  • 7
    • 0027594668 scopus 로고
    • Delivery of peptides and proteins through the blood-brain barrier
    • BICKEL U., YOSHIKAWA T. and PARDRIDGE W.M. - Delivery of peptides and proteins through the blood-brain barrier. - Adv. Drug Deliv. Rev., 10, 205-245, 1993.
    • (1993) Adv. Drug Deliv. Rev. , vol.10 , pp. 205-245
    • Bickel, U.1    Yoshikawa, T.2    Pardridge, W.M.3
  • 8
    • 0024822836 scopus 로고
    • Transplantation strategies in the treatment of Parkinson's disease : Experimental basis and clinical trials
    • LINDVALL O. and BJÖRKLUND A. - Transplantation strategies in the treatment of Parkinson's disease : experimental basis and clinical trials. Acta Neurol. Scand. 126, 197-210, 1989.
    • (1989) Acta Neurol. Scand. , vol.126 , pp. 197-210
    • Lindvall, O.1    Björklund, A.2
  • 9
    • 0028886936 scopus 로고
    • Gene therapy - A novel form of drug delivery
    • BLAU H.M. and SPINGER M.L. - Gene therapy - A novel form of drug delivery. New Engl. J. Med., 333, 18, 1995.
    • (1995) New Engl. J. Med. , vol.333 , pp. 18
    • Blau, H.M.1    Spinger, M.L.2
  • 11
    • 0000761915 scopus 로고
    • The use of silicone rubber as a carrier for prolonged drug therapy
    • FOLKMAN J. and LONG D.M. - The use of silicone rubber as a carrier for prolonged drug therapy. - J. Surg. Res., 4, 139-142, 1964.
    • (1964) J. Surg. Res. , vol.4 , pp. 139-142
    • Folkman, J.1    Long, D.M.2
  • 12
    • 0019795813 scopus 로고
    • Perivascular meningeal projections from cat trigeminal ganglia : Possible pathway for vascular headaches in man
    • MAYBERG M., LANGER R., ZERVAS N. and MOSKOWITZ M. - Perivascular meningeal projections from cat trigeminal ganglia : possible pathway for vascular headaches in man. -Science, 213, 228-230, 1981.
    • (1981) Science , vol.213 , pp. 228-230
    • Mayberg, M.1    Langer, R.2    Zervas, N.3    Moskowitz, M.4
  • 13
    • 0025884384 scopus 로고
    • Polymer implants for drug delivery in the brain
    • LANGER R. - Polymer implants for drug delivery in the brain. -J. Control. Rel., 16, 53-60, 1991.
    • (1991) J. Control. Rel. , vol.16 , pp. 53-60
    • Langer, R.1
  • 14
    • 0028298959 scopus 로고
    • Drug targeting into the central nervous system by stereotactic implantation of biodegradable microspheres
    • MENEI P., BENOIT J.P., BOISDRON-CELLE M., FOURNIER D., MERCIER P. and GUY G. - Drug targeting into the central nervous system by stereotactic implantation of biodegradable microspheres. - Neurosurgery, 34, 1058-1064, 1994.
    • (1994) Neurosurgery , vol.34 , pp. 1058-1064
    • Menei, P.1    Benoit, J.P.2    Boisdron-Celle, M.3    Fournier, D.4    Mercier, P.5    Guy, G.6
  • 18
    • 0023243959 scopus 로고
    • The intraneoplasic chemotherapy in a rat brain tumour model utilizing methotrexate-polymethylmethacrylate-pellets
    • RAMA B., MANDEL T., JANSEN J., DINGELDEIN E. and MENNEL H.D. - The intraneoplasic chemotherapy in a rat brain tumour model utilizing methotrexate-polymethylmethacrylate-pellets. - Acta Neurochir. Wien, 87, 70-75, 1987.
    • (1987) Acta Neurochir. Wien , vol.87 , pp. 70-75
    • Rama, B.1    Mandel, T.2    Jansen, J.3    Dingeldein, E.4    Mennel, H.D.5
  • 21
    • 0024340851 scopus 로고
    • Effects of microencapsulated monosialoganglioside GM1 on cholinergic neurons
    • MAYSINGER D., GAROFALO L., JALSENJAK I. and CUELLO A.C. - Effects of microencapsulated monosialoganglioside GM1 on cholinergic neurons. - Brain Res., 496, 165-172, 1989.
    • (1989) Brain Res. , vol.496 , pp. 165-172
    • Maysinger, D.1    Garofalo, L.2    Jalsenjak, I.3    Cuello, A.C.4
  • 22
    • 0028556843 scopus 로고
    • In vivo effects of brain derived neurotrophic factor released from microspheres
    • MITTAL S., COHEN A. and MAYSINGER D. - In vivo effects of brain derived neurotrophic factor released from microspheres. -NeuroReport, 5, 2577-2582, 1994.
    • (1994) NeuroReport , vol.5 , pp. 2577-2582
    • Mittal, S.1    Cohen, A.2    Maysinger, D.3
  • 23
    • 0028951001 scopus 로고
    • Novel delivery system for proteins using collagen as a carrier material : The minipellet
    • FUJIOKA K., TAKADA Y., SATO S. and MIYATA T. - Novel delivery system for proteins using collagen as a carrier material : the minipellet. - J. Control. Rel., 33, 307-315, 1995.
    • (1995) J. Control. Rel. , vol.33 , pp. 307-315
    • Fujioka, K.1    Takada, Y.2    Sato, S.3    Miyata, T.4
  • 24
    • 0019802018 scopus 로고
    • Aliphatic polyesters. II. The degradation of poly(DL-lactide), poly(ε-caprolactone), and their copolymers in vivo
    • PITT C.G., GRATZL M.M., KIMMEL G.L., SURLES J. and SCHINDLER A. - Aliphatic polyesters. II. The degradation of poly(DL-lactide), poly(ε-caprolactone), and their copolymers in vivo. - Biomaterials, 2, 215-220, 1981.
    • (1981) Biomaterials , vol.2 , pp. 215-220
    • Pitt, C.G.1    Gratzl, M.M.2    Kimmel, G.L.3    Surles, J.4    Schindler, A.5
  • 25
    • 0024745613 scopus 로고
    • In vitro and in vivo degradation of poly(D,L lactide/glycolide) type microspheres made by solvent evaporation method
    • SPENLEHAUER G., VERT M., BENOIT J.P. and BODDAERT A. - In vitro and in vivo degradation of poly(D,L lactide/glycolide) type microspheres made by solvent evaporation method. -Biomaterials, 10, 557-563, 1989.
    • (1989) Biomaterials , vol.10 , pp. 557-563
    • Spenlehauer, G.1    Vert, M.2    Benoit, J.P.3    Boddaert, A.4
  • 26
    • 0027222730 scopus 로고
    • Les polymères à base d'acides lactiques et glycolique et la délivrance contrôlée des principes actifs
    • MAUDUIT J. and VERT M. - Les polymères à base d'acides lactiques et glycolique et la délivrance contrôlée des principes actifs. - STP Pharma Sci., 3, 197-212, 1993.
    • (1993) STP Pharma Sci. , vol.3 , pp. 197-212
    • Mauduit, J.1    Vert, M.2
  • 30
    • 0025806708 scopus 로고
    • In vivo peptide release from poly(d,l-lactic acid-co-glycolic acid) copolymer 50/50 microspheres
    • RUIZ J.M. and BENOIT J.P. - In vivo peptide release from poly(d,l-lactic acid-co-glycolic acid) copolymer 50/50 microspheres. - J. Control. Rel., 16, 177-186, 1991.
    • (1991) J. Control. Rel. , vol.16 , pp. 177-186
    • Ruiz, J.M.1    Benoit, J.P.2
  • 33
    • 0022132637 scopus 로고
    • Bioerodible polyanhydrides as drug-carrier matrices. I. Characterization, degradation, and release characteristics
    • LEONG K.W., BROTT B.C. and LANGER R. - Bioerodible polyanhydrides as drug-carrier matrices. I. Characterization, degradation, and release characteristics. - J. Biomed. Mater. Res., 19, 941-955, 1985.
    • (1985) J. Biomed. Mater. Res. , vol.19 , pp. 941-955
    • Leong, K.W.1    Brott, B.C.2    Langer, R.3
  • 34
    • 0022643996 scopus 로고
    • Bioerodible polyanhydrides as drug carrier matrices. II : Biocompatibility and chemical reactivity
    • LEONG K.W., D'AMORE P., MARLETTA M. and LANGER R. -Bioerodible polyanhydrides as drug carrier matrices. II : Biocompatibility and chemical reactivity. - J. Biomed. Mater. Res., 20, 51-64, 1986.
    • (1986) J. Biomed. Mater. Res. , vol.20 , pp. 51-64
    • Leong, K.W.1    D'Amore, P.2    Marletta, M.3    Langer, R.4
  • 39
    • 0023835077 scopus 로고
    • Review : Chemotherapy for malignant gliomas
    • KORNBLITH P.L. and WALKER M. - Review : Chemotherapy for malignant gliomas. - J. Neurosurg., 68, 1-17, 1988.
    • (1988) J. Neurosurg. , vol.68 , pp. 1-17
    • Kornblith, P.L.1    Walker, M.2
  • 40
    • 0018848780 scopus 로고
    • Assumptions in the radiotherapy of glioblastoma
    • HOCHBERG F.H. and PRUITT A. - Assumptions in the radiotherapy of glioblastoma. - Neurology, 30, 907-911, 1980.
    • (1980) Neurology , vol.30 , pp. 907-911
    • Hochberg, F.H.1    Pruitt, A.2
  • 41
    • 0027497460 scopus 로고
    • Fluoropyrimidines as radiation sensitizers
    • LAWRENCE TS. and MAYBAUM J. - Fluoropyrimidines as radiation sensitizers. - Semin. Rad. Oncol., 3, 20-28, 1993.
    • (1993) Semin. Rad. Oncol. , vol.3 , pp. 20-28
    • Lawrence, T.S.1    Maybaum, J.2
  • 44
    • 0028907285 scopus 로고
    • Preparation and characterization of 5-fluorouracil-loaded microparticles as biodegradable anticancer drug carriers
    • BOISDRON-CELLE M., MENEI P. and BENOIT J.P. -Preparation and characterization of 5-fluorouracil-loaded microparticles as biodegradable anticancer drug carriers. - J. Pharm. Pharmacol., 47, 108-114, 1995.
    • (1995) J. Pharm. Pharmacol. , vol.47 , pp. 108-114
    • Boisdron-Celle, M.1    Menei, P.2    Benoit, J.P.3
  • 46
    • 0030003395 scopus 로고    scopus 로고
    • Effect of stereotactic implantation of biodegradable 5-fluorouracil-loaded microspheres in healthy and C6 glioma-bearing rats
    • MENEI P., BOISDRON-CELLE M., CROUE A., GUY G. and BENOIT J.P. - Effect of stereotactic implantation of biodegradable 5-fluorouracil-loaded microspheres in healthy and C6 glioma-bearing rats. - Neurosurgery, 39, 117-124, 1996.
    • (1996) Neurosurgery , vol.39 , pp. 117-124
    • Menei, P.1    Boisdron-Celle, M.2    Croue, A.3    Guy, G.4    Benoit, J.P.5
  • 48
    • 0030050282 scopus 로고    scopus 로고
    • Formulation of BCNU-loaded microspheres : Influence of drug stability and solubility on the design of the microencapsulation procedure
    • TORRES A.I., BOISDRON-CELLE M. and BENOIT J.P. -Formulation of BCNU-loaded microspheres : influence of drug stability and solubility on the design of the microencapsulation procedure. - J. Microencapsulation, 13, 41-51, 1996.
    • (1996) J. Microencapsulation , vol.13 , pp. 41-51
    • Torres, A.I.1    Boisdron-Celle, M.2    Benoit, J.P.3
  • 49
    • 0343873544 scopus 로고
    • Characterization and toxicity of biodegradable BCNU-loaded microspheres : Efficacy on C6 rat malignant glioma after intraperitoneal and stereotactic implantation
    • Strasbourg, 12-14 April
    • PAINBENI T., MENEI P., VENIER M.C., BOISDRON-CELLE M. and BENOIT J.P. - Characterization and toxicity of biodegradable BCNU-loaded microspheres : efficacy on C6 rat malignant glioma after intraperitoneal and stereotactic implantation. - 13th Pharmaceutical Technology Conference, Strasbourg, 12-14 April 1994, Vol. 1, pp. 65-74 .
    • (1994) 13th Pharmaceutical Technology Conference , vol.1 , pp. 65-74
    • Painbeni, T.1    Menei, P.2    Venier, M.C.3    Boisdron-Celle, M.4    Benoit, J.P.5
  • 50
    • 0027532239 scopus 로고
    • Polymers as controlled drug delivery devices for the treatment of malignant brain tumours
    • BREM H., WALTER K.A. and LANGER R. - Polymers as controlled drug delivery devices for the treatment of malignant brain tumours. - Eur. J. Pharm. Biopharm., 39, 2-7, 1993.
    • (1993) Eur. J. Pharm. Biopharm. , vol.39 , pp. 2-7
    • Brem, H.1    Walter, K.A.2    Langer, R.3
  • 51
    • 0027389182 scopus 로고
    • Interstitial chemotherapy of the 9L gliosarcoma : Controlled release polymers for drug delivery in the brain
    • TAMARGO R.J., MYSEROS J.S., EPSTEIN J.I., YANG M.B., CHASIN M. and BREM H. - Interstitial chemotherapy of the 9L gliosarcoma : controlled release polymers for drug delivery in the brain. - Cancer Res., 53, 329-333, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 329-333
    • Tamargo, R.J.1    Myseros, J.S.2    Epstein, J.I.3    Yang, M.B.4    Chasin, M.5    Brem, H.6
  • 52
    • 0024469755 scopus 로고
    • Controlled delivery of 1,3-bis(2-chloroethyl)-1-nitrosourea from ethylene-vinyl acetate copolymer
    • YANG M.B., TAMARGO R.J. and BREM H. - Controlled delivery of 1,3-bis(2-chloroethyl)-1-nitrosourea from ethylene-vinyl acetate copolymer. - Cancer Res., 49, 5103-5107, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 5103-5107
    • Yang, M.B.1    Tamargo, R.J.2    Brem, H.3
  • 53
    • 0028157552 scopus 로고
    • Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain
    • BREM H., TAMARGO R.J., OLIVI A., PINN M., WEINGART J.D., WHARAM M. and EPSTEIN J.I. - Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain. - J. Neurosurg., 80, 283-290, 1994.
    • (1994) J. Neurosurg. , vol.80 , pp. 283-290
    • Brem, H.1    Tamargo, R.J.2    Olivi, A.3    Pinn, M.4    Weingart, J.D.5    Wharam, M.6    Epstein, J.I.7
  • 56
    • 0029582768 scopus 로고    scopus 로고
    • The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant glioma
    • in press
    • BREM H., EWEND M.G., PIANTADOSI S., GREENHOOT J., BURGER P.C. and SISTI M. - The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant glioma. -J. Neuro-oncol., in press.
    • J. Neuro-oncol.
    • Brem, H.1    Ewend, M.G.2    Piantadosi, S.3    Greenhoot, J.4    Burger, P.C.5    Sisti, M.6
  • 57
    • 0022473091 scopus 로고
    • Formation and characterization of cisplatin loaded poly(d,l-lactide) microspheres for chemoembolization
    • SPENLEHAUER G., VEILLARD M. and BENOIT J.P. - Formation and characterization of cisplatin loaded poly(d,l-lactide) microspheres for chemoembolization. - J. Pharm. Sci., 75, 750-755, 1986.
    • (1986) J. Pharm. Sci. , vol.75 , pp. 750-755
    • Spenlehauer, G.1    Veillard, M.2    Benoit, J.P.3
  • 59
    • 0027473982 scopus 로고
    • Direct delivery of platinum-based antineoplastics to the central nervous system : A toxicity and ultrastructural study
    • OLIVI A., GILBERT M., DUNCAN K.L., CORDEN B., LENARTZ D. and BREM H. - Direct delivery of platinum-based antineoplastics to the central nervous system : a toxicity and ultrastructural study. - Cancer Chemother. Pharmacol., 31, 449-454, 1993.
    • (1993) Cancer Chemother. Pharmacol. , vol.31 , pp. 449-454
    • Olivi, A.1    Gilbert, M.2    Duncan, K.L.3    Corden, B.4    Lenartz, D.5    Brem, H.6
  • 60
  • 61
    • 0028898836 scopus 로고
    • Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas
    • JUDY K.D., OLIVI A., BUAHIN K.G., DOMB A., EPSTEIN J.I., COLVIN O.M. and BREM H. - Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas. - J. Neurosurg., 82, 481-486, 1995.
    • (1995) J. Neurosurg. , vol.82 , pp. 481-486
    • Judy, K.D.1    Olivi, A.2    Buahin, K.G.3    Domb, A.4    Epstein, J.I.5    Colvin, O.M.6    Brem, H.7
  • 62
    • 0029098633 scopus 로고
    • Local delivery of the topoisomerase I inhibitor camptothecin sodium prolongs survival in the rat intracranial 9L gliosarcoma model
    • WEINGART J.D., THOMPSON R.C., TYLER B., COLVIN O.M. and BREM H. - Local delivery of the topoisomerase I inhibitor camptothecin sodium prolongs survival in the rat intracranial 9L gliosarcoma model. - Int. J. Cancer, 62, 605-609, 1995.
    • (1995) Int. J. Cancer , vol.62 , pp. 605-609
    • Weingart, J.D.1    Thompson, R.C.2    Tyler, B.3    Colvin, O.M.4    Brem, H.5
  • 63
    • 0025924722 scopus 로고
    • Angiogenesis inhibition by minocycline
    • TAMARGO R.J., BOK R.A. and BREM H. - Angiogenesis inhibition by minocycline. - Cancer Res., 51, 672-675, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 672-675
    • Tamargo, R.J.1    Bok, R.A.2    Brem, H.3
  • 64
    • 0028943249 scopus 로고
    • The role of minocycline in treatment of 9L glioma
    • WEINGART J.D., SIPOS E.P. and BREM H. - The role of minocycline in treatment of 9L glioma. - J. Neurosurg., 82, 635-640, 1995.
    • (1995) J. Neurosurg. , vol.82 , pp. 635-640
    • Weingart, J.D.1    Sipos, E.P.2    Brem, H.3
  • 65
    • 0025145774 scopus 로고
    • Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate
    • TAMARGO R.J., LEONG K.W. and BREM H. - Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate. - J. Neuro-Oncol., 9, 131-138, 1990.
    • (1990) J. Neuro-Oncol. , vol.9 , pp. 131-138
    • Tamargo, R.J.1    Leong, K.W.2    Brem, H.3
  • 66
    • 0022642114 scopus 로고
    • The formation and characterization of hydrocortisone-loaded poly((±)-lactide) microspheres
    • CAVALIER M., BENOIT J.P. and THIES C. - The formation and characterization of hydrocortisone-loaded poly((±)-lactide) microspheres. - J. Pnarm. Pharmacol., 38, 249-253, 1986.
    • (1986) J. Pnarm. Pharmacol. , vol.38 , pp. 249-253
    • Cavalier, M.1    Benoit, J.P.2    Thies, C.3
  • 68
    • 0025735655 scopus 로고
    • Interstitial delivery of dexamethasone in the brain for the reduction of peritumoral edema
    • TAMARGO R.J., SILLS A.K., REINHARD C.S., PINN M.L., LONG D.M. and BREM H. - Interstitial delivery of dexamethasone in the brain for the reduction of peritumoral edema. - J. Neurosurg., 74, 956-961, 1991.
    • (1991) J. Neurosurg. , vol.74 , pp. 956-961
    • Tamargo, R.J.1    Sills, A.K.2    Reinhard, C.S.3    Pinn, M.L.4    Long, D.M.5    Brem, H.6
  • 71
    • 0028179159 scopus 로고
    • Transforming growth factor α-pseudomonas exotoxin fusion protein (TGFα-PE38) treatment of subcutaneous and intracranial human medulloblastoma and glioma xenografts in athymic mice
    • PHILIPS P.C., LEMOW C., CATTERALL M., COLVIN O.M., PASTAN I. and BREM H. - Transforming growth factor α-pseudomonas exotoxin fusion protein (TGFα-PE38) treatment of subcutaneous and intracranial human medulloblastoma and glioma xenografts in athymic mice. - Cancer Res., 54, 1008-1015, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 1008-1015
    • Philips, P.C.1    Lemow, C.2    Catterall, M.3    Colvin, O.M.4    Pastan, I.5    Brem, H.6
  • 72
    • 34548465529 scopus 로고
    • A morphological and ultrastructural investigation of normal mouse brain tissue after intra-cerebral injection of tumour necrosis factor
    • YAMASALKI T., KIKUCHI H., MORITAKE K., NAGAO S., IWASAKI K., PAINE J.T., KAGAWA T. and NAMBA Y. - A morphological and ultrastructural investigation of normal mouse brain tissue after intra-cerebral injection of tumour necrosis factor. - J. Neurosurg., 65, 659-663, 1992.
    • (1992) J. Neurosurg. , vol.65 , pp. 659-663
    • Yamasalki, T.1    Kikuchi, H.2    Moritake, K.3    Nagao, S.4    Iwasaki, K.5    Paine, J.T.6    Kagawa, T.7    Namba, Y.8
  • 73
    • 0024537248 scopus 로고
    • Controlled release of dopamine from a polymeric brain implant. In vitro characterization
    • FREESE A., SABEL B.A., SALTZMAN W.M., DURING M.J. and LANGER R. - Controlled release of dopamine from a polymeric brain implant. In vitro characterization. - Exp. Neurol., 103, 234-238, 1989.
    • (1989) Exp. Neurol. , vol.103 , pp. 234-238
    • Freese, A.1    Sabel, B.A.2    Saltzman, W.M.3    During, M.J.4    Langer, R.5
  • 75
    • 0024433446 scopus 로고
    • An encapsulated dopamine-releasing polymer alleviates experimental Parkinsonism in rats
    • WINN S.R., WAHLBERG L., TRESCO P.A. and AEBISCHER P. - An encapsulated dopamine-releasing polymer alleviates experimental Parkinsonism in rats. - Exp. Neurol., 105, 244-250, 1989.
    • (1989) Exp. Neurol. , vol.105 , pp. 244-250
    • Winn, S.R.1    Wahlberg, L.2    Tresco, P.A.3    Aebischer, P.4
  • 76
    • 0025190819 scopus 로고
    • Sustained behavioral recovery from unilateral nigrostriatal damage produced by the controlled release of dopamine from a silicone polymer pellet placed into the denervated striatum
    • BECKER J.B., ROBINSON T.E., BARTON P., SINTOV A., SIDEN R. and LEVY R.J. - Sustained behavioral recovery from unilateral nigrostriatal damage produced by the controlled release of dopamine from a silicone polymer pellet placed into the denervated striatum. - Brain Res., 508, 60-64, 1990.
    • (1990) Brain Res. , vol.508 , pp. 60-64
    • Becker, J.B.1    Robinson, T.E.2    Barton, P.3    Sintov, A.4    Siden, R.5    Levy, R.J.6
  • 77
    • 0023755343 scopus 로고
    • Implantable microencapsulated dopamine (DA) : A new approach for slow-release DA delivery into brain tissue
    • McRAE-DEGUEURCE A., HJORTH S., DILLON D.L., MASON D.W. and TICE T.R. - Implantable microencapsulated dopamine (DA) : a new approach for slow-release DA delivery into brain tissue. - Neurosci. Lett., 92, 303-309, 1988.
    • (1988) Neurosci. Lett. , vol.92 , pp. 303-309
    • McRae-Degueurce, A.1    Hjorth, S.2    Dillon, D.L.3    Mason, D.W.4    Tice, T.R.5
  • 78
    • 0026408595 scopus 로고
    • Micropencapsulated dopamine (DA). Induced restitution of function in 6-OH-DA denervated rat striatum in vivo : Comparison between two microsphere excipients
    • McRAE A., HJORTH S., MASON D.W., DILLON D.L. and TICE T.R. - Micropencapsulated dopamine (DA). Induced restitution of function in 6-OH-DA denervated rat striatum in vivo : comparison between two microsphere excipients. - J. Neural Transplant. Plast., 2, 165-173, 1991.
    • (1991) J. Neural Transplant. Plast. , vol.2 , pp. 165-173
    • McRae, A.1    Hjorth, S.2    Mason, D.W.3    Dillon, D.L.4    Tice, T.R.5
  • 79
    • 0028310282 scopus 로고
    • Transmitter-loaded polymeric microspheres induce regrowth of dopaminergic nerve terminals in striata of rats with 6-OH-DA induced parkinsonism
    • McRAE A. and DAHLSTRÖM A. - Transmitter-loaded polymeric microspheres induce regrowth of dopaminergic nerve terminals in striata of rats with 6-OH-DA induced parkinsonism. -Neurochem. Int., 25, 27-33, 1994.
    • (1994) Neurochem. Int. , vol.25 , pp. 27-33
    • McRae, A.1    Dahlström, A.2
  • 80
    • 0028490806 scopus 로고
    • Catecholamine-containing biodegradable microsphere implants as a novel approach in the treatment of central nervous system neurodegenerative disease. A review of experimental studies in DA-lesioned rats
    • McRAE A., LING E.A., HJORTH S., DAHLSTROM A., MASON D. and TICE T. - Catecholamine-containing biodegradable microsphere implants as a novel approach in the treatment of central nervous system neurodegenerative disease. A review of experimental studies in DA-lesioned rats. - Mol. Neurobiol., 9, 191-205, 1994.
    • (1994) Mol. Neurobiol. , vol.9 , pp. 191-205
    • McRae, A.1    Ling, E.A.2    Hjorth, S.3    Dahlstrom, A.4    Mason, D.5    Tice, T.6
  • 81
    • 0343873554 scopus 로고
    • Release of L-Dopa from HSA microspheres into the rat brain : In vitro and in vivo characterization by microdialysis
    • T.L. Whateley Ed., Harwood Academic Publisher, Chur
    • MAYSINGER D., JALSENJAK V., STOLNIK S. and JALSENJAK I. - Release of L-Dopa from HSA microspheres into the rat brain : in vitro and in vivo characterization by microdialysis. - In : Microencapsulation of Drugs, T.L. Whateley Ed., Harwood Academic Publisher, Chur, 1992, pp. 269-275.
    • (1992) Microencapsulation of Drugs , pp. 269-275
    • Maysinger, D.1    Jalsenjak, V.2    Stolnik, S.3    Jalsenjak, I.4
  • 82
    • 0028837084 scopus 로고
    • Macromolecular prodrugs. IV. Alginate-chitosan microspheres of PHEA-L-dopa adduct
    • FILIPOVIC-GRCIC J., MAYSINGER D., ZORC B. and JALSENJAK I. - Macromolecular prodrugs. IV. Alginate-chitosan microspheres of PHEA-L-dopa adduct. - Int. J. Pharm., 116, 39-44, 1995.
    • (1995) Int. J. Pharm. , vol.116 , pp. 39-44
    • Filipovic-Grcic, J.1    Maysinger, D.2    Zorc, B.3    Jalsenjak, I.4
  • 84
    • 0024419186 scopus 로고
    • Neurotrophic molecules
    • SNIDER W.D. and JOHSON E.M. - Neurotrophic molecules. -Ann. Neurol., 26, 489-506, 1989.
    • (1989) Ann. Neurol. , vol.26 , pp. 489-506
    • Snider, W.D.1    Johson, E.M.2
  • 86
    • 0027218098 scopus 로고
    • Neurotrophins and their receptors. Current concepts and implications for neurologic disease
    • EIDE F.F., LOWENSTEIN D.H. and REICHARDT L.F. -Neurotrophins and their receptors. Current concepts and implications for neurologic disease. - Exp. Neurol., 121, 200-214, 1993.
    • (1993) Exp. Neurol. , vol.121 , pp. 200-214
    • Eide, F.F.1    Lowenstein, D.H.2    Reichardt, L.F.3
  • 87
    • 0025287008 scopus 로고
    • Controlled release of nerve growth factor from a polymeric implant
    • POWELL E.M., SOBARZO M.R. and SALTZMAN W.M. -Controlled release of nerve growth factor from a polymeric implant. - Brain Res., 515, 309-311, 1990.
    • (1990) Brain Res. , vol.515 , pp. 309-311
    • Powell, E.M.1    Sobarzo, M.R.2    Saltzman, W.M.3
  • 88
    • 0029045339 scopus 로고
    • Distribution of nerve growth factor following direct delivery to the brain interstitium
    • KREWSON C.E., KLARMAN M.L. and SALTZMAN W.M. -Distribution of nerve growth factor following direct delivery to the brain interstitium. - Brain Res., 680, 196-206, 1995.
    • (1995) Brain Res. , vol.680 , pp. 196-206
    • Krewson, C.E.1    Klarman, M.L.2    Saltzman, W.M.3
  • 89
    • 0025115891 scopus 로고
    • NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria fornix lesion
    • HOFFMAN D., WAHLBERG L. and AEBISCHER P. - NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria fornix lesion. -Exp. Neurol., 110, 39-44, 1990.
    • (1990) Exp. Neurol. , vol.110 , pp. 39-44
    • Hoffman, D.1    Wahlberg, L.2    Aebischer, P.3
  • 90
    • 0026651992 scopus 로고
    • Protective effect of NGF atelocollagen mini-pellet on the hippocampal delayed neuronal death in gerbils
    • YAMAMOTO S., YOSHIMINE T., FUJITA T., KURODA R., IRIE T., FUJIOKA K. and HAYAKAWA T. - Protective effect of NGF atelocollagen mini-pellet on the hippocampal delayed neuronal death in gerbils. - Neurosci. Lett., 141, 161-165, 1992.
    • (1992) Neurosci. Lett. , vol.141 , pp. 161-165
    • Yamamoto, S.1    Yoshimine, T.2    Fujita, T.3    Kuroda, R.4    Irie, T.5    Fujioka, K.6    Hayakawa, T.7
  • 91
    • 0026628154 scopus 로고
    • Sustained release of nerve growth factor from biodegradable polymer microspheres
    • CAMARATA P.J., SURYANARAYANAN R., TURNER D.A., PARKER R.G. and EBNER T.J. - Sustained release of nerve growth factor from biodegradable polymer microspheres. -Neurosurgery, 30, 313-319, 1992.
    • (1992) Neurosurgery , vol.30 , pp. 313-319
    • Camarata, P.J.1    Suryanarayanan, R.2    Turner, D.A.3    Parker, R.G.4    Ebner, T.J.5
  • 92
    • 85013550264 scopus 로고
    • Sustained intracerebral delivery of nerve growth factor with biodegradable polymer microspheres
    • MENDEZ A., CAMARATA P.J., SURYANARAYANAN R. and EBNER T.J. - Sustained intracerebral delivery of nerve growth factor with biodegradable polymer microspheres. - Methods Neurosci., 21, 150-167, 1994.
    • (1994) Methods Neurosci. , vol.21 , pp. 150-167
    • Mendez, A.1    Camarata, P.J.2    Suryanarayanan, R.3    Ebner, T.J.4
  • 93
    • 0026566924 scopus 로고
    • Hyaluronane derivative microspheres as NGF delivery devices : Preparation methods and in vitro release characterization
    • GHEZZO E., BENEDETTI L., ROCHIRA M., BIVIANO F. and CALLEGARO L. - Hyaluronane derivative microspheres as NGF delivery devices : preparation methods and in vitro release characterization. - Int. J. Pharm., 87, 21-29, 1992.
    • (1992) Int. J. Pharm. , vol.87 , pp. 21-29
    • Ghezzo, E.1    Benedetti, L.2    Rochira, M.3    Biviano, F.4    Callegaro, L.5
  • 94
    • 0026741763 scopus 로고
    • Microencapsulated nerve growth factor : Effects on the forebrain neurons following devascularizing cortical lesions
    • MAYSINGER D., JALSENJAK I. and CUELLO A.C. -Microencapsulated nerve growth factor : effects on the forebrain neurons following devascularizing cortical lesions. - Neurosci. Lett., 140, 71-74, 1992.
    • (1992) Neurosci. Lett. , vol.140 , pp. 71-74
    • Maysinger, D.1    Jalsenjak, I.2    Cuello, A.C.3
  • 95
    • 0028793476 scopus 로고
    • NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation
    • RIDDLE D.R., LO D.C. and KATZ L.C. - NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation. - Nature, 378, 189-191, 1995.
    • (1995) Nature , vol.378 , pp. 189-191
    • Riddle, D.R.1    Lo, D.C.2    Katz, L.C.3
  • 96
    • 0027177069 scopus 로고
    • Effects of coencapsulated NGF and GM1 in rats with cortical lesions
    • MAYSINGER D., FILIPOVIC-GRCIC J. and CUELLO A.C. -Effects of coencapsulated NGF and GM1 in rats with cortical lesions. - NeuroReport, 4, 971-974, 1993.
    • (1993) NeuroReport , vol.4 , pp. 971-974
    • Maysinger, D.1    Filipovic-Grcic, J.2    Cuello, A.C.3
  • 97
    • 0026730136 scopus 로고
    • Sustained release of papaverine for the treatment of cerebral vasospasm : In vitro evaluation of release kinetics and biological activity
    • HEFFEZ D.S. and LEONG K.W. - Sustained release of papaverine for the treatment of cerebral vasospasm : in vitro evaluation of release kinetics and biological activity. - J. Neurosurg., 77, 783-787, 1992.
    • (1992) J. Neurosurg. , vol.77 , pp. 783-787
    • Heffez, D.S.1    Leong, K.W.2
  • 98
    • 0029020140 scopus 로고
    • Prolongation of spinal anaesthesia with bupivacaine-loaded (DL-lactide) microspheres
    • ESTEBE J.P., LE CORRE P., MALLEDANT Y., CHEVANNE F. and LEVERGE R. - Prolongation of spinal anaesthesia with bupivacaine-loaded (DL-lactide) microspheres. - Anesth. Analg., 81, 99-103, 1995
    • (1995) Anesth. Analg. , vol.81 , pp. 99-103
    • Estebe, J.P.1    Le Corre, P.2    Malledant, Y.3    Chevanne, F.4    Leverge, R.5
  • 99
    • 0029163511 scopus 로고
    • Motor and blood pressure effects of epidural sustained-release bupivacaine from polymer microspheres : A dose response study in rabbits
    • MALINOVSKY J.M., BERNARD J.M., LE CORRE P., DUMAND J.B., LEPAGE J.Y., LE VERGE R. and SOURON R. - Motor and blood pressure effects of epidural sustained-release bupivacaine from polymer microspheres : a dose response study in rabbits. -Anesth. Analg., 81, 519-524, 1995.
    • (1995) Anesth. Analg. , vol.81 , pp. 519-524
    • Malinovsky, J.M.1    Bernard, J.M.2    Le Corre, P.3    Dumand, J.B.4    Lepage, J.Y.5    Le Verge, R.6    Souron, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.