Mutation rate and excess African heterozygosity

Human Biology

Volumn 69, Issue 6, 1997, Pages 785-792

  Relethford, John H ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Heterozygosity; Modern human origins; Mutation

Indexed keywords

EID: 0031543464     PISSN: 00187143     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Bowcock, A.M., A. Ruiz-Linares, J. Tomfohdre et al. 1994. High resolution of human evolutionary trees with polymorphic microsatellites. Nature 368:455-457.
2. Crow, J.F., and M. Kimura. 1970. An Introduction to Population Genetics Theory. Minneapolis, MN: Burgess.
3. n polymorphisms in world populations. Am. J. Hum. Genet. 56:461-474.
4. Harpending, H.C., J.H. Relethford, and S.T. Sherry. 1996. Methods and models for understanding human diversity. In Molecular Biology and Human Diversity, A.J. Boyce and C.G.N. Mascie-Taylor, eds. Cambridge, England: Cambridge University Press, 283-299.
5. Harpending, H.C., S.T. Sherry, A.R. Rogers et al. 1993. The genetic structure of ancient human populations. Curr. Anthropol. 34:483-496.
6. Jorde, L.B., M.J. Bamshad, W.S. Watkins et al. 1995. Origins and affinities of modern humans: A comparison of mitochondrial and nuclear genetic data. Am. J. Hum. Genet. 57:523-538.
7. Jorde, L.B., A.R. Rogers, M. Bamshad et al. 1997. Microsatellite diversity and the demographic history of modern humans. Proc. Natl. Acad. Sci. USA 94:3100-3103.
8. Li, W.-H. 1977. Distribution of nucleotide differences between two randomly chosen cistrons in a finite population. Genetics 85:331-337.
9. Lynch, M. 1988. The rate of polygenic mutation. Genet. Res. 51:137-148.
10. Malécot, G. 1969. The Mathematics of Heredity, revised and translated edition. San Francisco, CA: W.H. Freeman.
11. Relethford, J.H. 1995. Genetics and modern human origins. Evol. Anthropol. 4:53-63.
12. Relethford, J.H., and J. Blangero. 1990. Detection of differential gene flow from patterns of quantitative variation. Hum. Biol. 62:5-25.
13. Relethford, J.H., and H.C. Harpending. 1994. Craniometric variation, genetic theory, and modern human origins. Am. J. Phys. Anthropol. 95:249-270.
14. Rogers, A.R. 1995. Genetic evidence for a Pleistocene population explosion. Evolution 49:608-615.
15. Rogers, A.R., and L.B. Jorde. 1995. Genetic evidence on modern human origins. Hum. Biol. 67:1-36.
16. Rogers, A.R., and L.B. Jorde. 1996. Ascertainment bias in estimates of average heterozygosity. Am. J. Hum. Genet. 58:1033-1041.
17. Tishkoff, S.A., E. Dietzch, W. Speed et al. 1996. Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science 271:1380-1387.