An enzymatic tissue digestion method for fibre biopersistence studies

Annals of Occupational Hygiene

Volumn 41, Issue 6, 1997, Pages 721-723

  Searl, Alison ^a   Cullen, Richard T ^a  

^a INSTITUTE OF OCCUPATIONAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS; DUST; FIBERS; HYDROCHLORIC ACID; HYDROGEN PEROXIDE; OXIDATION; PULMONARY DISEASES; RISK ASSESSMENT; SCANNING ELECTRON MICROSCOPY; TISSUE;

BLEACH SENSITIVE DUSTS; ENZYMATIC TISSUE DIGESTION METHOD; FIBRE BIOPERSISTENCE; LUNG; POTASSIUM HYDROXIDE; SODIUM HYDROXIDE; SODIUM HYPOCHLORITE;

OCCUPATIONAL DISEASES;

ASBESTOS FIBER; ENZYME; HYDROCHLORIC ACID; HYDROGEN PEROXIDE; HYPOCHLORITE SODIUM; MINERAL FIBER; POTASSIUM HYDROXIDE; SODIUM HYDROXIDE;

ARTICLE; DUST EXPOSURE; HUMAN; HUMAN TISSUE; LUNG BURDEN; LUNG PARENCHYMA; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TECHNIQUE;

EID: 0031542077     PISSN: 00034878     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4878(97)00023-9     Document Type: Article

References (9)

1. Davis, J. M. G. (1994) The role of clearance and dissolution in determining the durability or biopersistence of mineral fibers. Environmental Health Perspectives 102, 113-117.
2. Davis, J. M. G., Gylseth, B. and Morgan, A. (1986) Assessment of mineral fibres from human lung tissue. Thorax 41, 167-175.
3. Evans, R. and Cullen, R. T. (1984) In situ proliferation of intratumour macrophages. Journal of Leukocyte Biology 35, 561-572.
4. Kelly, D. P., Williams, S. J., Kennedy, G. L. Jr. and Lee, K. P. (1985) Recovery and characterization of lung-deposited Kevlar aramid fibers in rats. Toxicologist 5, 129.
5. Nenadic, C. M. and Crable, J. V. (1970) Enzymatic digestion of human lung tissue. American Industrial Hygiene Association Journal 41, 81-85.
6. Searl, A. A comparative study of the clearance of respirable para-aramid, chrysotile and glass fibre from rat lungs. Annals of Occupational Hygiene 41, 217-233.
7. Searl, A. Clearance of respirable para-aramid from rat lungs, Inhaled Particles VIII, 148-153.
8. Warheit, D. B., Hwang, H. C. and Achinko, L. (1991) Assessments of lung digestion methods for recovery of fibers. Environmental Research 54, 183-193.
9. World Health Organisation (WHO), (1985) Reference methods for measuring air-borne man-made mineral fiber (MMMF), World Health Organisation, Copenhagen, 55.