Asymmetric synthesis of a xanthine dehydrogenase inhibitor (S)-(-)-BOF-4272 : Mechanism of chiral diaryl sulfoxide formation

Phosphorus, Sulfur and Silicon and Related Elements

Volumn 120-121, Issue , 1997, Pages 305-315

  Hashimoto, Kinji ^a   Matsugi, Masato ^a   Fukuda, Norio ^a   Kurogi, Yasuhisa ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Asymmetric synthesis; BOF 4272; Mechanism; Xanthine dehydrogenase inhibitor

Indexed keywords

EID: 0031529492     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426509708043958     Document Type: Article

References (35)

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35. Preminimizations of models by molecular mechanics (MM) calculation with ESFF force field were conducted in Discover 95.0.0, available from MSI. Semiempirical optimizations and LUMO calculations of models by PM3 were conducted in InsightII/Mopac, available from MSI. Coordinates were transferred to Chem 3D Plus, version 3.1.2, for visualization.