In pursuit of higher purity: Use of13C NMR and13C-enriched substrates to trace impurity generation and removal in the synthesis of atorvastatin

Organic Process Research and Development

Volumn 1, Issue 4, 1997, Pages 320-324

  Wade, Robert A ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031521956     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op9701088     Document Type: Article

References (4)

1. Roth, B. D.; Sliskovic, D. R; Trivedi, B. K. Annu. Rep. Med. Chem. 1989, 24, 147.
2. Pedersen, T. R.; et al. Lancet 1994, 344, 1383.
3. Brower, P. L.; Butler, D. E.; Deering, C. F.; Le, T. V.; Millar, A.; Nanninga, T. N.; Roth, B. D. Tetrahedron Lett. 1992,33,2279. Baumann, K. L; Butler, D. E.; Deering, C. F.; Mennen, K. E.; Millar, A.; Nanninga, T. N.; Palmer, C. W.; Roth, B. D. Tetrahedron Lett. 1992, 33, 2283.
4. Brower, P. L.; Butler, D. E.; Deering, C. F.; Le, T. V.; Millar, A.; Nanninga, T. N.; Roth, B. D. Tetrahedron Lett. 1992,33,2279. Baumann, K. L; Butler, D. E.; Deering, C. F.; Mennen, K. E.; Millar, A.; Nanninga, T. N.; Palmer, C. W.; Roth, B. D. Tetrahedron Lett. 1992, 33, 2283.