Effect of endotoxin-induced pyrexia in rabbits on the physiological, biochemical and pharmacokinetic parameters of piroxicam

Chinese Pharmaceutical Journal

Volumn 49, Issue 3, 1997, Pages 185-193

  Qamar, Shadab ^a   Bukhari, Nadeem Irfan ^b   Ahmad, Mahmood ^b   Muzzafar, Naeem A ^a  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

^b THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

Author keywords

Bioavailability; Disposition kinetics; Endotoxins; Pharmacokinetics; Piroxicam; Pyrexia

Indexed keywords

ESCHERICHIA COLI ENDOTOXIN; INDOMETACIN; PIROXICAM;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD PH; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; FEVER; GLUCOSE BLOOD LEVEL; LIPID BLOOD LEVEL; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; RABBIT;

EID: 0031474718     PISSN: 10161015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Song, C. S.; Gelb, N. A.; Wolf, S. M. The Influence of Pyrogen Induced Fever on the Salicylamide Metabolism in Man. J. Clin Invest. 1972, 51, 2959-2966.
2. Van Gogh, H.; Van Miert, A. S. J. P. A. M. The Absorption of Sulphonamides from Gastrointestinal Tract During Pyrogen Induced Fever in Kids and Goats. Zbl. Vet. Med. A. 1977, 24, 503-510.
3. Ahmads A. H.; Bahga, H. S.; Sharma, L. D. Pharmacokinetics of Gentamicin Following Single Dose Intravenous Administration in Normal and Febrile Goats. J. Vet Pharmacol. Ther. 1994, 17(5), 369-373.
4. Groothuis, D. G.; Van Miert, A. S. J. P. A. M.; Ziv. G.; Nouws. J. F. M. Effect of Experimental. Escherichia coli Endotoxaemia on Ampicillin: Amoxycillin Blood Levels After Oral andParentral Administration in Calves. J. Vet. Pharmacol. Ther. 1978, 1, 81-84.
5. Ladefoged, O. Pharmacokinetics of Trimethoprim (TMP) in Normal and Febrile Rabbits. Acta Pharmacol et. Toxicol. 1977, 41, 507-514.
6. Ladefoged, O. The Effect of E. coli. Endotoxin on the Gastrointestinal Absorption of Antipyrine in Rabbits. XIII. Nord. Vet. Congr. Abo. P. 1978, 363.
7. Ahmad, M.; Muzaffarf N. A; Nawaz, M. Bioavailability and Disposition Kinetics of Erythromycin Following Oral Administration in Normal and Febrile Rabbits. Pakistan J. Pharmacol. 1993, 10, 1-4.
8. Ahmad, M.; Nawaz, M. Effect of E. coli Endotoxin Induced Fever on the Pharmacokinetics of Sulphadiazine in Rabbits. Pakistan Vet. J. 1995, 15, 187-191.
9. Wisemans E. H.; Chang, Y. H.; Lombardino, J. G. Piroxicam, A Novel Anti Inflammatory Agent. Arzeim-Forsch. 1976, 26, 1300-1303.
10. Schiantarelli P.; Cadel, S. Piroxicam Pharmacologic Activity and Gastrointestinal Damage by Oral and Rectal Route. Arzeim-Forsch. 1981, 31, 87-92.
11. Milne, G. M.; Twomey, T. M. The Analgesic Properties of Piroxicam in Animals and Correlation with Experimentally Determined Plasma Levels. Agents Actions. 1980, 10, 31-37.
12. Benjamin, M. Outline of Veterinary Clinical Pathology. The Iowa State University Press Ames, Iowa, USA. 1978; PP 52.
13. Barham, D.; Trinder, P. Kit Method for the Analysis of Plasma Glucose. Analyst. 1972, 97, 142-145.
14. Gornall, A. G.; Bordawill, C. J.; David, M. M. Determination of Serum Proteins by Means of Biuret Reaction. J. Biol. Chem. 1949, 177, 751-766.
15. Doumas, B. T.; Watson, W. A.; Biggs, H. G. Kit Method for the Analysis of Albumin in Plasma. Clin. Chem. Acta. 1971, 31, 87.
16. Zollner, N.; Krisch, K. Kit Method for the Determination of Total Lipids in Plasma. Ges. Exp. Med. 1962, 135, 545.
17. Tsai, Y. H.; Hsu, L. R.; Naito, S. I. Simultaneous Determination of Piroxicam and Its Main Metabolite in Plasma and Urine by High Performance Liquid Chromatography. Int. J. Pharm. 1985, 24, 101-108.
18. Johnston, A.; Woollrad, R. PK II (Computer Program), MS-DOS Version 2.02, UK. 1988.
19. Akaike, H. An Information Criterion (AIC). Math. Sci. 1976, 14, 5-9.
20. SPSS (Computer Program), MS-Windows Version 6, SPSS Inc. USA. 1993.
21. Canterow, A.; Schepartz, B. Biochemistry, 4th ed.; W. B. Saunders Co.: Philadelphia, 1968; pp 807-808.
22. Kaneko, J. J.; Cornelius, C. E. Clinical Biochemistry of Domestic Animals, 2nd ed. Vol. 1; Academic Press Inc.: New York, 1971; pp 99.
23. Baume, P. E.; Nicholls, A.; Baxter, C. H. Inhibition of Gastric Acid Secretion by a Purified Bacterial Lipopolysaccharide. Nature. 1967, 215, 59-60.
24. Wyllie, I. H.; Limbosch, I. M.; Nyhus, L. M. Inhibition of Gastric Secretion by Bacterial Lipyopolysaccharide. Nature. 1967, 215, 879.
25. Van Miert, A. S. J. P. A. M.; Parra, De-La. Inhibition of Gastric Emptying by Endotoxin in Conscious Rats and Modification of This Response by Drugs Effecting the Autonomic Nervous System. Arch. Int. Pharmacodyn. 1970, 184, 27-33.
26. Gibaldi, M.; Schwartz, M. A.; Plaut, M. E. Serum Levels of Penicillins: A Pharmacokinetic View. Antimicrob. Agents. Chemother. 1968, 378-381.
27. Pennington, J. E.; Dale, D. C.; Reynolds, H. Y.; MacLowry, J. D. Gentamicin Sulfate Pharmacokinetics, Lower Levels of Gentamicin in Blood During Fever. J. Inf. Dis. 1975. 132, 270-275.
28. Van Miert, A. S. J. P. A. M. Inhibition of Gastric Motility by Endotoxin (Bacterial Lipopolysaccharide) in Conscious Goats and Modification of This Response by Drugs Effecting the Splanchnectomy, Adrenalectomy, or Adrenergic Blocking Agents. Arch. Int. Pharmacodynam. 1971, 193, 405-414.
29. Leek, B. F.; Van Miert, A. S. J. P. A. M. An Analysis of The Pyrogen Induced Inhibition of Gastric Motility in Sheep. J. Physiol. 1971, 215, 28-29.
30. Lahsev, L. Pharmacokinetic Research on Amoxycillin in Agricultural Animals. Vet. Med. Nauki. 1986, 23, 6-82.
31. Baggot, J. D. Principles of Drug Disposition in Domestic Animals. The Basis of Veterinary Clinical Pharmacology; W. B. Saunders Co.: Philadilphia, 1977; pp 144-188.
32. Friis, C.; Ladefoged, O. Renal Clearance of Sulphathiazole in Pigs with E. coli Endotoxaemia. Zbl. Vet. Med. A. 1979, 26, 146-151.
33. Ladefoged, O. Endotoxin Induced Changes in the Pharmacokinetics of Warfarin in Rabbits. Acta Vet. Scand. 1978, 19, 479-486.