Diminished salt appetite in spontaneously hypertensive rats following local administration of the angiotensin II antagonist saralasin in the median preoptic area

Behavioural Pharmacology

Volumn 8, Issue 8, 1997, Pages 752-756

  Tanaka, J ^a   Hori, K ^b   Nomura, M ^b  

^a NARUTO UNIVERSITY OF EDUCATION   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Angiotensin II; Median preoptic nucleus; Salt appetite; Saralasin; Spontaneously hypertensive rat; Wistar Kyoto rat

Indexed keywords

ANGIOTENSIN ANTAGONIST; SARALASIN;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FLUID INTAKE; HYPERTENSION; INTRACEREBRAL DRUG ADMINISTRATION; MALE; NONHUMAN; PREOPTIC AREA; RAT; SODIUM APPETITE;

ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; APPETITE; DRINKING; HYPERTENSION; INJECTIONS; MALE; PREOPTIC AREA; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SARALASIN; SODIUM, DIETARY;

EID: 0031473865     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008877-199712000-00011     Document Type: Article

References (31)

1. Buggy J and Johnson AK (1977) Preoptic-hypothalamic periventricular lesions: thirst deficits and hypernatremia. American Journal of Physiology, 233, R44-R52.
2. De Luca LA Jr, Galaverna O, Schulkin J, Yao S and Epstein AN (1991) The anteroventral wall of the third ventricle and the angiotensinergic component of need-induced sodium intake in the rat. Brain Research Bulletin, 28, 73-87.
3. Elfont RM, Epstein AN and Fitzsimons JT (1984) Involvement of the renin-angiotensin system in captopril-induced sodium appetite in the rat. Journal of Physiology (London), 354, 11-27.
4. Fitts DA (1991) Effects of lesions of the ventral median preoptic nucleus or subfornical organ on drinking and salt appetite after deoxycorticosterone acetate or yohimbine. Behavioral Neuroscience, 105, 721-726.
5. Fitts DA and Masson DB (1989) Forebrain sites of action for drinking and salt appetite to angiotensin or captopril. Behavioral Neuroscience, 103, 865-872.
6. Fitts DA and Masson DB (1990) Preoptic angiotensin and salt appetite. Behavioral Neuroscience, 104, 643-650.
7. Fitts DA, Tjepkes DS and Bright RO (1989) Salt appetite and lesions of the ventral part of the ventral median preoptic nucleus. Behavioral Neuroscience, 104, 818-827.
8. Gardiner TW and Stricker EM (1985a) Hyperdipsia in rats after electrolytic lesions of nucleus medianus. American Journal of Physiology, 248, R214-R223.
9. Gardiner TW and Stricker EM (1985b) Impaired drinking responses of rats with lesions of nucleus medianus: circadian dependence. American Journal of Physiology, 248, R224-R230.
10. Lehr D, Goldman HW and Casner P (1973) Renin-angiotensin role in thirst: paradoxical enhancement of drinking by angiotensin converting enzyme inhibitor. Science, 182, 1031-1034.
11. Lind RW and Johnson AK (1980) A further characterization of the effects of AV3V lesions on ingestive behavior. American Journal of Physiology, 245, R83-R90.
12. Lind RW and Johnson AK (1982) Subfornical organ-median preoptic connections and drinking and pressor responses to angiotensin II. Journal of Neuroscience, 2, 1043-1051.
13. Lind RW, Swanson LW and Ganten D (1984) Angiotensin II immunoreactivity in neural afferents and efferents of the subfornical organ of the rat. Brain Research, 321, 209-215.
14. Lind RW, Swanson LW and Ganten D (1985) Organization of angiotensin II immunoreactive cells and fibers in the rat central nervous system: an immunohistochemical study. Neuroendocrinology, 40, 2-24.
15. Masson DB and Fitts DA (1989) Subfornical organ connectivity and drinking to captopril or carbachol in rats. Behavioral Neuroscience, 103, 873-880.
16. Mendelsohn FAO, Quirion R, Saavedra JM, Aguilera G and Catt KJ (1984) Autoradiographic localization of angiotensin II receptor in rat brain. Proceedings of National Academy of Science USA, 81, 1575-1579.
17. Nelson OS (1988) Altered angiotensin II sensitivity of neurons in the organum lamina terminalis region of the spontaneously hypertensive rat. Brain Research, 444, 46-52.
18. Paxinos G and Watson C (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, Sydney.
19. Phillips MI (1983) New evidence for brain angiotensin and for its role in hypertensions. Federal Proceedings of American Society of Experimental Biolouy, 42, 2667-2672.
20. Saavedra JM, Fernandez-Paradal J and Chevillard C (1982) Angiotensin-converting enzyme in discrete area of the rat forebrain and pituitary gland. Brain Research, 245, 317-325.
21. Schulkin J, Eng R and Miselis RR (1983) The effects of disconnecting the subfornical organ on behavioral and physiological responses to alteration of body sodium. Brain Research, 263, 351-355.
22. Stamler JF, Raizada MK, Ferrows RE and Phillips MI (1980) Increased specific binding of angiotensin II in the organum vasculosum of the laminae terminalis area of the spontaneously hypertensive rat brain. Neuroscience Letters, 17. 173-177.
23. 3H] Captopril binding to membarance associated angiotensin converting enzyme. Biochemical and Biophysiological Research Communication, 112, 1027-1033.
24. Tanaka J and Nomura M (1993) Involvement of neurons sensitive to angiotensin II in the median preoptic nucleus in the drinking response induced by angiotensin II activation of the subfornical organ in rats. Experimental Neurology, 119, 235-239.
25. Tanaka J, Saito H and Kada H (1987) Subfornical organ and hypothalamic paraventricular nucleus connections with median preoptic nucleus neurons: an electrophysiological study in the rat. Experimental Brain Research, 68, 579-585.
26. Thunhorst RL, Ehrlich KJ and Simpson JB (1990) Subfornical organ participates in salt appetite. Behavioral Neuroscience, 104, 637-642.
27. Thunhorst RL, Fitts DA and Simpson JB (1987) Separation of captopril effects on salt and water intake by subfornical organ lesions. American Journal of Physiology, 252, R409-R418.
28. Thunhorst RL, Fitts DA and Simpson JB (1989) Angiotensin-converting enzyme in subfornical organ mediates captopril-induced drinking, Behavioral Neuroscience, 103, 1302-1310.
29. Thunhorst RL, Fitts DA and Simpson JB (1987) Separation of captopril effects on salt and water intake by subfornical organ lesions. American Journal of Physiology, 252, R409-R418.
30. Wright JW and Harding JW (1992) Regulatory and behavioral responses. Brain Research Review, 17, 227-262.
31. Yongue BG, Angulo JA, McEwen BS and Myers MM (1991) Brain and liver angiotensinogen messenger RNA in Genetic Hypertensive and normotensive rats. Hypertension, 17, 485-491.