Use of positron emission tomography to measure the effects of nalmefene on D1 and D2 dopamine receptors in rat brain

Brain Research

Volumn 775, Issue 1-2, 1997, Pages 183-188

  Unterwald, Ellen M ^a,b   Tsukada, Hideo ^c   Kakiuchi, Takeharu ^c   Kosugi, Tsuyoshi ^c   Nishiyama, Shingo ^c   Kreek, Mary Jeanne ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c CENTRAL RESEARCH LABORATORY   (Japan)

Author keywords

Dopamine receptor binding; Imaging; Nalmefene; Opioid receptor antagonist; PET; Rat brain

Indexed keywords

3 METHYLSPIPERONE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BRAIN RECEPTOR; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DRUG VEHICLE; NALMEFENE; OPIATE ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC SYSTEM; DRUG EFFECT; DRUG RECEPTOR BINDING; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LIGAND BINDING; LOCOMOTION; MALE; NONHUMAN; OSMOTIC MINIPUMP; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT; REINFORCEMENT; SUBCUTANEOUS DRUG ADMINISTRATION;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; BRAIN CHEMISTRY; CEREBRAL CORTEX; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; NEOSTRIATUM; PILOT PROJECTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SPIPERONE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0031473537     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00931-1     Document Type: Article

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