T helper type 2 like cytokine responses to peptides from P0 and P2 myelin proteins during the recovery phase of Guillain-Barre syndrome

Journal of the Neurological Sciences

Volumn 153, Issue 1, 1997, Pages 54-60

  Dahle, Charlotte ^a   Ekerfelt, Christina ^a   Vrethem, Magnus ^a   Samuelsson, Margareta ^b   Ernerudh, Jan ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b Institution of Public Health and Clinical Medicine   (Sweden)

Author keywords

Guillain Barre syndrome; IFN ; IL 4; Myelin; P0; P2; T cells

Indexed keywords

CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN; INTERLEUKIN 4; MYELIN BASIC PROTEIN; SYNTHETIC PEPTIDE;

ADULT; AGED; ANTIBODY PRODUCTION; ARTICLE; CLINICAL ARTICLE; DEMYELINATING DISEASE; GUILLAIN BARRE SYNDROME; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; INFLAMMATORY DISEASE; INTRAVENOUS DRUG ADMINISTRATION; MALE; PLASMAPHERESIS; POLYRADICULITIS; PRIORITY JOURNAL;

ADULT; AGED; CYTOKINES; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; MALE; MIDDLE AGED; MYELIN P0 PROTEIN; MYELIN P2 PROTEIN; PEPTIDES; POLYRADICULONEUROPATHY; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0031473251     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(97)00178-0     Document Type: Article

References (29)

1. Asbury A.K., Arnason B.G.W., Karp H.R., McFarlin D.E. Criteria for diagnosis of Guillain-Barré syndrome. Ann. Neurol. 3:1978;565-566.
2. Bansil S., Mithen F.A., Cook S.D., Sheffet A., Robowsky-Kochan C. Clinical correlation with serum-soluble interleukin-2 receptor levels in Guillain-Barré syndrome. Neurology. 41:1991;1302-1305.
3. Bøyum A. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest. 21(Suppl.):1968;77-79.
4. Créange A., Bélec L., Clair B., Raphael J.-C., Gherardi R.K. Circulating tumor necrosis factor (TNF)-α and soluble TNF-α receptors in patients with Guillain-Barré syndrome. J. Neuroimmunol. 68:1996;95-99.
5. Czerkinsky C., Tarkowski A., Nilsson L.-Å., Ouchterlony Ö., Nygren H., Gretzer C. Reverse enzyme-linked immunospot (RELISPOT) assay for detection of cells secreting immunoreactive substances. J. Immunol. Methods. 72:1984;489-496.
6. Dahle C., Vrethem M., Ernerudh J. T lymphocyte subset abnormalities in peripheral blood from patients with the Guillain-Barré syndrome. J. Neuroimmunol. 53:1994;219-225.
7. Ekerfelt C., Ernerudh J., Vrethem M. Th1 like responses to myelin peptides in polyneuropathy associated with monoclonal gammopathy. Clin. Exp. Immunol. 108:1997;516-522.
8. Feasby T.E. Treatment of Guillain-Barré syndrome with anti-T cell monoclonal antibodies. J. Neurol. Neurosurg. Psychiatry. 54:1991;51.
9. Hartung H.-P., Pollard J.D., Harvey G.K., Toyka K.V. Immunopathogenesis and treatment of the Guillain-Barré syndrome-part I. Muscle Nerve. 18:1995;137-153.
10. Hartung H.-P., Pollard J.D., Harvey G.K., Toyka K.V. Immunopathogenesis and treatment of the Guillain-Barré syndrome-part II. Muscle Nerve. 18:1995;154-164.
11. Hartung H.-P., Reiners K., Schmidt B., Stoll G., Toyka K.V. Serum interleukin-2 concentrations in Guillain-Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy; comparison with other neurological diseases of presumed immunopathogenesis. Ann. Neurol. 30:1991;48-53.
12. Hartung H.P., Hughes R.A.C., Taylor W.A., Heiniger K., Reiners K., Toyka K.V. T cell activation in Guillain-Barré syndrome and in MS; elevated levels of soluble IL-2 receptors. Neurology. 40:1990;215-218.
13. Karp C.L., El-Safi S.H., Wynn T.A., Satti M.M.H., Kordofani A.M., Hashim F.A., Hag-Ali M., Neva F.A., Nutman T.B., Sacks D.L. In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma. J. Clin. Invest. 91:1993;1644-1648.
14. Khalili-Shirazi A., Hughes R.A.C., Brostoff S.W., Linington C., Gregson N. T cell responses to myelin proteins in Guillain-Barré syndrome. J. Neurol. Sci. 111:1992;200-203.
15. Liblau R.S., Singer S.M., McDevitt H.O. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol. Today. 16:1995;34-38.
16. Linington C., Lassmann H., Ozawa K., Kosin S., Mongan L. Cell adhesion molecules of the immunoglobuline supergene family as tissue-specific autoantigens: induction of experimental allergic neuritis (EAN) by P0-protein specific T cell lines. Eur. J. Immunol. 22:1992;1813-1817.
17. Mosmann T.R., Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol. Today. 17:1996;138-146.
18. Mustafa M.I., Diener P., Höjeberg B., Meide P.V.d., Olsson T. T cell immunity and interferon-g secretion during experimental allergic encephalomyelitis in Lewis rats. J. Neuroimmunol. 31:1991;165-177.
19. Olee T., Powers J.M., Brostoff S.W. A T cell epitope for experimental allergic neuritis. J. Neuroimmunol. 19:1988;167-173.
20. Osterman P.G., Fagius J., Lundemo G., Pihlstedt P., Pirskanen R., Side'n Å., Säfwenberg J. Beneficial effects of plasma exchange in acute inflammatory polyradiculoneuropathy. Lancet. 2:1984;1296-1299.
21. Parronchi P., DeCarli M., Manetti R., Simonelli C., Piccinni M.-P., Macchia D., Maggi E., DelPrete G., Ricci M., Romagnani S. Aberrant interleukin (IL)-4 and IL-5 production in vitro by CD4+ helper T cells from atopic subjects. Eur. J. Immunol. 22:1992;1615-1620.
22. Pirmez C., Yamamura M., Uyemura K., Paes-Oliveira M., Conceicao-Silva F., Modlin R.L. Cytokine patterns in the pathogenesis of human leishmaniasis. J. Clin. Invest. 91:1993;1390-1395.
23. Röcken M., Racke M., Shevach E.M. IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease. Immunol. Today. 17:1996;225-231.
24. Shoenfeld Y., George J., Peter J.B. Guillain-Barré as an autoimmune disease. Int. Arch. Allergy Immunol. 109:1996;318-326.
25. Simon A.K., Seipelt E., Sieper J. Divergent T-cell cytokine patterns in inflammatory arthritis. Proc. Natl. Acad. Sci. U.S.A. 91:1994;8562-8566.
26. Taylor W.A., Hughes R.A.C. T lymphocyte activation antigens in Guillain-Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy. J. Neuroimmunol. 24:1989;33-39.
27. Voskuhl R.R., Martin R., Bergman C., Dalal M., Ruddle N.H., McFarland H.F. T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes. Autoimmunity. 15:1993;137-143.
28. Zhu J., Link H., Mix E., Olsson T., Huang W.-X. Th1-like cell responses to peripheral nerve myelin components over the course of experimental allergic neuritis in Lewis rats. Acta Neurol. Scand. 90:1994;19-25.
29. Zhu J., Mix E., Olsson T., Link H. Cellular mRNA expression of interferon-gamma, IL-4 and transforming growth factor-beta (TGF-β) by rat mononuclear cells stimulated with peripheral nerve myelin antigens in experimental allergic neuritis. Clin. Exp. Immunol. 98:1994;306-312.