Apoptosis of CD4+ T cells induced after contact with HIV1-infected or non-infected macrophages

Research in Virology

Volumn 148, Issue 6, 1997, Pages 383-396

  Godard, C M ^a   Serries H ^a   Fulachier, C ^a   Chermann, J C ^a  

^a INSERM   (France)

Author keywords

Apoptosis; CD4 receptor; gp120; HIV; Macrophage; T lymphocyte

Indexed keywords

CD4 ANTIGEN; DNA FRAGMENT; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN ANTIBODY; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; VIRUS ENVELOPE PROTEIN; ZIDOVUDINE;

ARTICLE; CELL CONTACT; CELL KILLING; CONTROLLED STUDY; CROSS LINKING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOBLASTOID CELL LINE; LYMPHOCYTE DEPLETION; MACROPHAGE; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; VIRUS INHIBITION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RICKETTSIA SP. PAR; RNA VIRUSES; STAPHYLOCOCCUS PHAGE 3A;

EID: 0031472907     PISSN: 09232516     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2516(97)83628-X     Document Type: Article

References (46)

1. Ameisen, J.C. & Capron, A. (1991), Cell dysfunction and depletion in AIDS : the programmed cell death hypothesis. Immunol.Today, 12, 102-105.
2. Ameisen, J.C. (1994), Programmed cell death (apoptosis) and cell survival regulation: relevance to AIDS and cancer. AIDS, 8, 1197-1213.
3. Badley, A.D., McElhinny, J.A., Leibson, P.J., Lynch, D.H., Alderson, M.R. & Paya, C.V. (1996), Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. J. Virol., 70, 199-206.
4. + T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor. J. Exp. Med., 185, 55-64.
5. Banda, N.K., Bernier, J., Kurahara, D.K., Kurrle, R., Haigwood, N., Sekaly, R.P. & Finkel, T.H. (1992), Cross-linking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J. Exp. Med., 176, 1099-1106.
6. Chermann, J.C. (1990), HIV-associated diseases: acute and regressive encephalopathy in a seropositive man. Res. Virol., 141, 137-141.
7. Cohen, D.I., Tani, T., Tian, H., Boone, E., Samelson, L.E. & Lane, H.C. (1992), Participation of tyrosine phosphorylation in the cytopathic effect of human immunodeficiency virus-1. Science, 256, 542-545.
8. Collman, R. & Nathanson, N. (1992), Human immunodeficiency virus type-1 infection of macrophages. Sem. Virol., 3, 185-202.
9. + T-cells. J. Gen. Virol., 76, 681-690.
10. Fauci, A.S. (1993), Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science, 262, 1011-1018.
11. Finkel, T.H., Tudor-Williams, G., Banda, N.K., Cotton, M.F., Curiel, T., Monks, C., Baba, T.W., Ruprecht, R.M. & Kupfer, A. (1995), Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV-and SIV-infected lymph nodes. Nature Med., 1, 129-134.
12. Gavrieli, Y., Sherman, Y. & Ben-Sasson, S.A. (1992), Identification of programmed cell death in situ vin specific labeling of nuclear DNA fragmentation J. Cell. Biol., 119, 493-501.
13. Gougeon, M.L., Olivier, R., Garcia, S., Guétard, D. Dragic, T., Dauguet, C. & Montagnier, L. (1991). Mise en évidence d'un processus d'engagement vers la mort cellulaire par apoptose dans les lymphocytes de patients infectés par le VIH. C.R. Acad. Sci., 312, 529-537.
14. Gougeon, M.L., Laurent-Crawford, A.G., Hovanessian, A.G. & Montagnier, L. (1993), Direct and indirect mechanisms mediating apoptosis during HIV infection: contribution to in vivo CD4 T-cell depletion. Sem. Immunol., 5, 187-194.
15. + T cells from human immunodeficiency virus-infected asymptomatic individuals. J. Exp. Med., 175, 331-340.
16. Harada, S., Koyanagi, Y. & Yamamoto, N. (1985), Infection of HTLV-III/LAV in HITLV-1-carrying cells MT-2 and MT-4 and application in a plaque assay. Science, 229, 563-566.
17. Hovanessian, A.G. (1994), Apoptosis in HIV infection: the role of extracellular and transmembrane glycoproteins, in "Apoptosis. II. The molecular basis of apoptosis in disease" (L.D. Tomei & F.O. Cope) (pp. 21-42). Cold Spring Harbor Laboratory, New York.
18. Kent, J.J., Stent, G., Sonza, S., Hunter, S.D. & Crowe, S.M. (1994), HIV infection of monocyte-derived macrophages reduces Fc and complement receptors expression. Clin. Exp. Immunol., 95, 450-454.
19. Kroemer, G., Zamzami, N. & Susin, S.A. (1997), Mitochondrial control of apoptosis. Immunol. Today, 18, 44-51.
20. Laurent-Crawford, A.G., Krust, B., Muller, S., Riviére, Y., Rey-Cuillé, M.A., Béchet, J.M., Montagnier, L. & Hovanessian, A.G. (1991), The cytopathic effect of HIV is associated with apoptosis. Virology, 185, 829-839.
21. Laurent-Crawford, A.G., Krust, B., Rivière, Y., Desgranges, C., Muller, S., Kieny, M.P., Dauguet, C. & Hovanessian, A.G. (1993), Membrane expression of HIV envelope glycoproteins triggers apoptosis in CD4 cells. AIDS Res. Hum. Retrovir., 9, 761-773.
22. + target cells. Res. Virol., 146, 5-17.
23. Looney, R.J., Abraham, G.N. & Anderson, C.L. (1986), Human monocytes and U937 cells bear two distinct Fc receptors for IgG. J. Immunol., 136, 1641-1647.
24. Meltzer, M.S. & Gendelman, H.E. (1992), Mononuclear phagocytes as targets, tissue reservoirs, and immunoregulatory cells in human immunodeficienccy virus disease. Curr. Topics Microbiol. Immunol., 181, 239-263.
25. Meyaard, L., Otto, S.A., Jonker, R.R., Mijnster, M.J., Keet, R.P.M. & Miedema, F. (1991), Programmed death of T cells in HIV-1 infection. Science, 257, 217-219.
26. Miyoshi, I., Kubonishi, I., Yoshimoto, S. et al. (1981), Type C virus particles in cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukemia T cells. Nature (Lond.), 294, 770-771.
27. + lymphocyte depletion in AIDS, in "Retroviruses of human AIDS and related animal diseases" (M. Girard & L. Valette) (pp. 9-17). Pasteur Mérieux, Paris.
28. Mustelin, T. & Altman, A. (1989), Do CD4 and CD8 control T-cell activation via a specific tyrosine protein kinase? Immunol. Today, 10, 189-192.
29. Newell, M.K., Haughn, L.J., Maroun, C.R. & Julius, M.H. (1990), Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen. Nature (Lond.), 347, 286-289.
30. Olafsson, K., Smith, M.S., Marshburn, P., Carter, S.G. & Haskill, S. (1991), Variation of HIV infectibility of macrophages as a function of donor, stage of differentiation and site of origin. J. Acquired Immune Defic. Syndr., 4, 154-164.
31. Oyaizu, N., McCloskey, T.W., Coronesi, M., Chirmule, N., Kalyanaraman, V.S. & Pahwa, S. (1993), Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1-infected patients and in CD4 cross-linked PBMCs from normal individuals. Blood, 82, 3392-3400.
32. + T cells apoptosis. J. Immunol., 158, 2456-2463.
33. Perno, C.F., Aquaro, S., Rosenwirth, B., Balestra, E., Peichl, P., Billich, A., Villani, N. & Calio, R. (1994), In vitro activity of inhibitors of late stages of the replication of HIV in chronically infected macrophages. J. Leukoc. Biol., 56, 381-386.
34. Ren, Y., & Savill, J. (1995), Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis. J. Immunol., 154, 2366-2374.
35. Rey, M.A., Spire, B., Dormont, D., Barré-Sinoussi, F., Montagnier, L. & Chermann, J.C. (1984), Characterization of the RNA-dependent DNA polymerase of a new human T-lymphotropic retrovirus (lymphadenopathy associated virus). Biochem. Biophys. Res. Commun., 121, 126-133.
36. Rey-Cuillé, M.A., Galabru, J., Laurent-Crawford A.L., Krust, B., Montagnier, L. & Hovanessian, A. (1994), HIV-2 EHO isolate has a divergent envelope gene and induces single cell killing by apoptosis. Virology, 202, 471-476.
37. Rudd, C.E. (1990), CD4, CD8 and the TCR-CD3 complex : a novel class of protein-tyrosine kinase receptor. Immunol. Today, 11, 400-406.
38. Sattentau, Q.J., Dalgleish, A.G., Weiss, R.A. & Beverley, P.C.L. (1986), Epitopes of CD4 antigen and the HIV infection. Science, 234, 1120-1127.
39. Sauvaigo, S., Barlet, V., Guettari, N., Innocenti, P., Parmentier, F., Bastard, C., Seigneurin, J.M., Chermann, J.C., Teoule, R. & Marchand, J. (1993), Standardized nested polymerase chain reaction-based assay for detection of human immunodeficiency virus type 1 DNA in whole blood lysates. J. Clin. Microbiol., 31, 1066-1074.
40. Savill, J., Hogg, N., Ren, Y. & Haslett, C. (1992), Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J. Clin. Invest., 90, 1513-1522.
41. Savill, J., Fadok, V., Henson, P. & Haslett, C. (1993), Phagocyte recognition of cells undergoing apoptosis. Immunol. Today, 14, 131-136.
42. Schmidtmayerova, H., Bolmont, C., Baghdiguian, S., Hirsch, I. & Chermann, J.C. (1992), Distinct pattern of infection and replication of HIV-1 strains in bloodderived macrophages. Virology, 190, 124-133.
43. Schmidtmayerova, H., Gayet, O., Guettari, N., Bolmont, C., Hirsch, I. & Chermann, J.C. (1993), Characterization of HIV-1-PAR, a macrophage-tropic strain: cell tropism, virus/cell entry and nucleotide sequence of the envelope glycoprotein. Res. Virol., 144, 21-26.
44. Terai, C., Kornbluth, R.S., Pauza, C.D., Richman, D.D. & Carson, D.A. (1991), Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1. J. Clin. Invest., 87, 1710-1715.
45. Wain-Hobson, S., Sonigo, P., Danos, O., Cole, S. & Alizon, M. (1985), Nucleotide sequence of the AIDS virus, LAV. Cell, 40, 9-17.
46. Willie, A.H., Morris, R.G., Smith, A.L. & Dunlop, D. (1984), Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J. Pathol., 142, 62-77.