Effector molecules in expression of the antimicrobial activity of macrophages against Mycobacterium avium complex: Roles of reactive nitrogen intermediates, reactive oxygen intermediates, and free fatty acids

Journal of Leukocyte Biology

Volumn 62, Issue 6, 1997, Pages 795-804

  Akaki, Tatsuya ^a   Sato, Katsumasa ^a   Shimizu, Toshiaki ^a   Sano, Chiaki ^a   Kajitani, Hiroko ^a   Dekio, Satoshi ^a   Tomioka, Haruaki ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

H2O2 mediated halogenation system; Microbicidal activity; Nitric oxide synthase; Phospholipase A2

Indexed keywords

ARACHIDONIC ACID; FATTY ACID; HYDROGEN PEROXIDE; LINOLENIC ACID; NITROGEN DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; EFFECTOR CELL; HOST RESISTANCE; LISTERIA MONOCYTOGENES; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM INTRACELLULARE AVIUM; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

EID: 0031470751     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.62.6.795     Document Type: Article

References (43)

1. Benson, C. A., Ellner, J. J. (1993) Mycobacterium avium complex infection and AIDS: Advances in theory and practice. Clin. Infect. Dis. 17, 7-20.
2. Falkinham, J. O. (1996) Epidemiology of infection by nontuberculous mycobacteria. Clin. Microbiol. Rev. 9, 177-215.
3. Flesch, I. E. A., Kaufmann, S. H. E. (1991) Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: Role of reactive nitrogen intermediates. Infect. Immun. 59, 3213-3218.
4. Chan, J., Xing, Y., Magliozzo, R. S., Bloom, B. R. (1992) Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175, 1111-1122.
5. O'Brien, L., Carmichael, J., Lowrie, D. B., Andrew, P. W. (1994) Strains of Mycobacterium tuberculosis differ in susceptibility to reactive nitrogen intermediates in vitro. Infect. Immun. 62, 5187-5190.
6. Chan, J., Kaufmann, S. H. E. (1994) Immune mechanisms of protection. In Tuberculosis, Pathogenesis, Protection, and Control (B. R. Bloom, ed.), Washington, DC: ASM Press, 389-415.
7. Chan, J., Tanaka, K., Carroll, D., Flynn, J., Bloom, B. R. (1995) Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis. Infect. Immun. 63, 736-740.
8. Denis, M. (1991) Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium killing effector mechanism depends on the generation of reactive nitrogen intermediates. J. Leukoc. Biol. 49, 380-387.
9. Doi, T., Ando, M., Akaike, T., Suga, M., Sato K., Maeda, H. (1993) Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis. Infect. Immun. 61, 1980-1989.
10. Yamada, Y., Saito, H., Tomioka, H., Jidoi, J. (1987) Relationship between the susceptibility of various bacteria to active oxygen species and to intracellular killing by macrophages. J. Gen. Microbiol. 133, 2015-2021.
11. 2-Fe-mediated halogenation system supplemented with antimicrobial agents. Int. J. Lepr. 57, 628-632.
12. Tomioka, H., Saito, H. (1993) Macrophage chemiluminescence induced by interaction with transparent and opaque variants of Mycobacterium intracellulare. J. Gen. Microbiol. 139, 3011-3015.
13. Sarmento, A., Appelberg, R. (1996) Involvement of reactive oxygen intermediates in tumor necrosis factor alpha-dependent bacteriostasis of Mycobacterium avium. Infect. Immun. 64, 3224-3230.
14. Kanai, K., Kondo, E. (1979) Antibacterial and cytotoxic aspects of long-chain fatty acids as cell surface events: selected topics. Jpn. J. Med. Sci. Biol. 32, 135-174.
15. Saito, H., Tomioka, H., Yoneyama, T. (1984) Growth of group IV mycobacteria on medium containing various saturated and unsaturated fatty acids. Antimicrob. Agents Chemother. 26, 164-169.
16. Saito, H., Tomioka, H. (1988) Susceptibilities of transparent, opaque, and rough colonial variants of Mycobacterium avium complex to various fatty acids. Antimicrob. Agents Chemother. 32, 400-402.
17. Kondo, E., Kanai, K. (1984) Phospholipase activity of the membrane fraction of phagocytes in relation to its antibacterial property. Kekkaku 59, 395-402.
18. Yamada, Y., Saito, H., Tomioka, H., Jidoi, J. (1987) Susceptibility of micro-organisms to active oxygen species: sensitivity to the xanthine oxidase-mediated antimicrobial system. J. Gen. Microbiol. 133, 2007-2014.
19. Kondo, E., Kanai, K. (1981) Host lipids in tuberculosis infection. I. Phospholipids. Kekkaku 56, 1-9.
20. Tomioka, H., Sato, K., Maw, W. W., Saito, H. (1995) The role of tumor necrosis factor, interferon-γ, transforming growth factor-β, and nitric oxide in the expression of immunosuppressive functions of splenic macrophages induced by Mycobacterium avium complex infection. J. Leukoc. Biol. 58, 704-712.
21. 2 in endothelial cells. Biochem. Pharmacol. 49, 57-63.
22. Tomioka, H., Saito, H. (1993) Characterization of immunosuppressive functions of murine peritoneal macrophages induced with various agents. J. Leukoc. Biol. 51, 24-31.
23. Hibbs, J. B., Jr., Vavrin, Z., Taintor, Z. (1987) Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite. Science 235, 473-476.
24. Akaike, T., Yoshida, M., Miyamoto, Y., Sato, K., Kohno, M., Sasamoto, K., Miyazaki, K., Ueda, S., Maeda, H. (1993) Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/NO through a radical reaction. Biochem. 32, 827-832.
25. 2. Br. Med. Bull. 39, 260-264.
26. Stuehr, D. J., Nathan, C. F. (1989) A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med. 169, 1543-1555.
27. Sturgill-Koszycki, S., Schlesinger, P., Chakraborty, P., Haddix, P. L., Collins, H. L., Fok, A. K., Allen, R. D., Gluck, S. L., Heuser, J., Russell, D. G. (1994) Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 263, 678-681.
28. Crowle, A. J., Dahl, R., Ross, E., May, M. H. (1991) Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect. Immun. 59, 1823-1831.
29. Sturgill-Koszycki, S., Schlesinger, P. H., Chakraborty, P., Haddix, P. L., Collins, H. L., Fok, A. G., Allen, R. D., Gluck, S. L., Heuser, J., Russell, D. G. (1994) Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 263, 678-681.
30. Holsti, M. A., Allen, P. M. (1996) Processing and presentation of an antigen of Mycobacterium avium require access to an acidified compartment with active proteases. Infect. Immun. 64, 4091-4098.
31. Belisle, J. T., Brennan, P. J. (1994) Molecular basis of colony morphology in Mycobacterium avium. Res. Microbiol. 145, 237-242.
32. Zhu, L., Gunn, C., Beckman, J. S. (1992) Bactericidal activity of peroxynitrite. Arch. Biochem. Biophys. 298, 452-457.
33. Tomioka, H., Saito, H., Sato, K., Dawson, D. J. (1993) Comparison of the virulence for mice of Mycobacterium avium and Mycobacterium intracellulare identified by DNA probe test. Microbiol. Immunol. 37, 259-264.
34. Cooper, A. M., Dalton, D. K., Stewart, T. A., Griffin, J. P., Russell, D. G., Orme, I. M. (1993) Disseminated tuberculosis in interferon gamma gene disrupted mice. J. Exp. Med. 178, 2243-2247.
35. Kamijo, R., Le, J., Shapiro, D., Havell, E. A., Huang, S., Aguet, M., Bosland, M., Vilcek, J. (1993) Mice that lack the interferon gamma receptor have profoundly altered response to infection with BCG and subsequent challenge with lipopolysaccharide. J. Exp. Med. 178, 1435-1440.
36. Denis, M. (1994) Human monocytes/macrophages: NO or no NO? J. Leukoc. Biol. 55, 682-684.
37. Schoedon, G., Schneemann, M., Walter, R., Blau, N., Hofer, S., Schaffner, A. (1995) Nitric oxide and infection: another view. Clin. Infect. Dis. 21, S152-S157.
38. Kumararatne, D. S. (1997) Tuberculosis and immunodeficiency - of mice and men. Clin. Exp. Immunol. 107, 11-14.
39. Schneemann, M., Schoedon, G., Hofer, S., Blau, N., Guerro, L., Schaffner, A. (1993) Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J. Infect. Dis. 167, 1358-1363.
40. Zhang, X. O., Laubach, V. E., Alley, E. W., Edwards, K. A., Sherman, P. A., Russell, S. W., Murphy, W. J. (1996) Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthetase gene to LPS/interferon-gamma. J. Leukoc. Biol. 59, 575-585.
41. Nicholson, S., Bonencini-Almeida, M., Silva, J. R. L., Nathan, C., Xie, Q., Mumford, R., Weidner, J. R., Calaycay, J., Geng, J., Boechat, N., Linhares, C., Rom, W., Ho, J. L. (1996) Inducible nitric oxide synthetase in pulmonary alveolar macrophages from patients with tuberculosis. J. Exp. Med. 183, 2293-2302.
42. Pacelli, R., Wink, D. A., Cook, J. A., Krishna, M. C., DeGraff, W., Friedman, N., Tsokos, M., Samuni, A., Mitchell, J. B. (1995) Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli. J. Exp. Med. 182, 1469-1479.
43. Warwick-Davies, J., Lowrie, D. B., Cole, P. J. (1995) Selective deactivation of human monocyte functions by TGF-β. J. Immunol. 155, 3186-3193.