Acute and chronic effects of different bile acids on indomethacin-induced intestinal inflammation

Inflammation

Volumn 21, Issue 6, 1997, Pages 553-567

  Arndt, Holger ^a   Kullmann, Frank ^a   Schölmerich, Jürgen ^a   Palitzsch, Klaus Dieter ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; INDOMETACIN; LEUKOTRIENE B4; TAUROCHENODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; ENTERITIS; FECES ANALYSIS; LEUKOCYTE ADHERENCE; MALE; MESENTERY; NONHUMAN; PH; RAT; SMALL INTESTINE; VENULE;

ANIMALS; BILE ACIDS AND SALTS; INDOMETHACIN; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; INTESTINE, SMALL; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031470310     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1027390920570     Document Type: Article

References (51)

1. BENNETT, R A., P. H. RUBIN, and D. H. PRESENT. 1991. Frequency of inflammatory bowel disease in offspring of couples both presenting with inflammatory bowel disease. Gastroenterology 100:1638-1643.
2. SARTOR, R. B., D. E. BENDER, and L. C. HOLT. 1992. Susceptibility of inbred rat strains to intestinal and extraintestinal inflammation induced by indomethacin. Gastroenterology 102:A690 (abstract).
3. SARTOR, R. B. 1993. Antimicrobial therapy of inflammatory bowel disease: Implications for pathogenesis and management. Can. J. Gastroenterol 7:132-138.
4. TEAHON, K., I. BJARNASON, M., PEARSON, and A. J. LEVI. 1990. Ten years experience with an elemental diet in the management of Crohn's disease. Gut 31:1133-1137.
5. SHANAHAN, F. 1993. Pathogenesis of ulcerative colitis. Lancet 342:407-411.
6. GREENWALD, B. D., and S. P. JAMES. 1995. Immunology of inflammatory bowel disease. Curr. Opin. Gastroenterol. 11:298-304.
7. KAM, L., T. T. PIZARRO, and F. COMINELLI. 1995. Cytokines and chemokines in inflammatory bowel disease. Curr. Opin. Gastroenterol. 11:305-309.
8. TAZUMA, S. A., OZAWA, T. YAMAMOTO, Y. TAMAHASHI, K. TAKESHI, S. M. SAIDI, C. G. ICHOROH, and P. G. WAIYAKI. 1993. Ecological study on the intestinal bacterial flora of patients with diarrhea. Clin. Infect. Dis. 16:S77-S82.
9. KRUIS, W., H.-D. KALEK, F. STELLAARD, and G. PAUMGARTNER. 1986. Altered fecal bile acid pattern in patients with inflammatory bowel disease. Digestion 35:189-198.
10. FEDORAK, R. 1995. Naturally occurring and experimental models of inflammatory bowel disease. In Inflammatory bowel disease. 4th edition. J. B. Kirsner and R. G. Shorter, editors. Williams and Wilkins, Baltimore. 71-95.
11. BANARJEE, A. K., and T. J. PETERS. 1990. Experimental non-steroidal anti-inflammatory drug-induced enteropathy in the rat: Similarities to inflammatory bowel disease and effect of thromboxane synthetase inhibitors. Gut 31:1358-1364.
12. SARTOR, R. B. 1991. Animal models of intestinal inflammation: Relevance to inflammatory bowel disease. In Inflammatory bowel disease. R. P. MacDermott and W. F. Stenson, editors. Elsevier, New York. 337-353.
13. BECK, W. S., H. T. SCHNEIDER, K. DIETZEL, B. NUERNBERG, and K. BRUNE. 1990. Gastrointestinal ulcerations induced by anti-inflammatory drugs in rats. Arch. Toxicol. 64:210-217.
14. BRODIE, D. A., P. G. COOK, B. J. BAUER, and G. E. DAGLE. 1970. Indomethacin-induced intestinal lesions in the rat. Toxicol. Appl. Pharmacol. 17:615-624.
15. ROBERT, A., and T. ASANO. 1977. Resistance of germfree rats to indomethacin-induced intestinal lesions. Prostaglandins 14:333-341.
16. KENT, T. H., R. M. CARDELLI, and F. W. STAMLER. 1969. Small intestinal ulcers and intestinal flora in rats given indomethacin, Am. J. Pathol. 54:231-245.
17. SATOH, H., P. H. GUTH, and M. I. GROSSMAN. 1981. Role of bacteria in gastric ulceration produced by indomethacin in the rat. Gastroenterology 84:483-489.
18. ARNDT, H., K.-D. PALITZSCH, and J. SCHÖLMERICH. 1995. Various diets affect leukocyte adherence and emigration to a different extent in the indomethacin model of chronic intestinal inflammation. Gastroenterology 108:A774 (abstract).
19. YAMADA, T., E. DEITCH, R. D. SPECIAN, M. A. PERRY, R. B. SARTOR, and M. B. GRISHAM. 1993. Mechanisms of acute and chronic intestinal inflammation induced by indomethacin. Inflammation 17: 641-662.
20. ARNDT, H., K.-D. PALITZSCH, J. SCHÖLMERICH, and D. N. GRANGER. 1995. Bile duct ligation and fasting reduce microcirculatory disturbances in indomethacin-induced intestinal inflammation in the rat. Gastroenterology 108:A773 (abstract).
21. POUPON, R. E., B. BALKAU, E. ESHWÈGE, R. POUPON, and the UDCA-PBC study group. 1991. A multicenter controlled trial of ursodiol for the treatment of primary biliary cirrhosis. N. Engl. J. Med. 324:1548-1554.
22. HOFMANN, A. F. 1990. Bile acid hepatotoxicity and the rationale of UDCA therapy in chronic cholestatic liver disease: Some hypothesis. In Strategies for the treatment of hepatobiliary diseases. G. Paumgartner, A. Stiehl, L. Barbara, and E. Roda, editors. Kluwer Academic Publishers, Dordrecht. 13-33.
23. CALMUS, Y., P. GANE, P. ROUGER, and R. POUPON. 1990. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: Effect of ursodeoxycholic acid. Hepatology 11:12-15.
24. CALMUS, Y., J. GUECHOT, P. PODEVIN, M.-T. BONNEFIS, J. GIBOUDEAU, and R. POUPON. 1992. Differential effects of chenodeoxycholic and ursodeoxycholic acids on interleukin I, interleukin 6 and tumor necrosis factor-α production in monocytes. Hepatology 16:719-723.
25. LEUSCHNER, U., S. GÜDÜLTÜNA, S. BHATTI, A. ELZE, M. IMHOF, T. YOU, and G. ZIMMER. 1995. TUDCA and UDCA are incorporated into hepatocyte membranes: Different sites, but similar effects. Ital. J. Gastroenterol. 27:376-377.
26. CHADWICK, V. S., S. F. PHILLIPS, and A. F. HOFMANN. 1977. Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals. Gastroenterology 73:247-251.
27. SCHÖLMERICH, J., M.-S. BECHER, K. SCHMIDT, R. SCHUBERT, B. KREMER. S. FELDHAUS, and W. GEROK. 1984. Influence of hydroxylation and conjugation of bile salts on their membrane-damaging properties - Studies on isolated hepatocytes and liquid membrane vesicles. Hapatology 4:661-666.
28. 2 reduces bile acid-mediated intestinal vascular injury in rats. Gastroenterology 102:1295-1305.
29. QUIST, R. G., H.-T. TON-NU, J. LILLIENAU, A. F. HOFMANN, and K. E. BARRETT. 1991. Activation of mast cells by bile acids. Gastroenterology 101:446-456.
30. HEUMANN, D. M., and R. BAJAJ. 1994. Ursodeoxycholate conjugates protect against disruption of cholesterol-rich membranes by bile salts. Gastroenterology 106:1333-1341.
31. KITANI, K., 1995. The protective effect of hydrophilic bile acids on bile acid hepatotoxicity in the rat. Ital. J. Gastroenterol. 27:366-371.
32. SOKOL, R. J., B. M. WINKLHOFER-ROOB, M. W. DEVEREAUX, and J. M. MCKIM, JR. 1995. Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology 109:1249-1256.
33. AZER, S. A., S. A. COVERDALE, K. BYTH, G. C. FARRELL, and N. H. STACEY. 1996. Sequential changes in serum levels of individual bile acids in patients with chronic cholestatic liver disease. J. Gastroenterol. Hepatol. 11:208-215.
34. GRANGER, D. N., J. N. BENOIT, M. SUZUKI, and M. B. GRISHAM. 1989. Leukocyte adherence to venular endothelium during ischemia/reperfusion. Am. J. Physiol. 257:G683-G688.
35. ARNDT, H., K.-D. PALITZSCH, M. B. GRISHAM, and D. N. GRANGER. 1994. Metronidazole inhibits leukocyte-endothelial cell adhesion in rat mesenteric venules. Gastroenterology 106:1271-1276.
36. DAVIS, M. J. 1987. Determination of volumetric flow in capillary tubes using an optical Doppler velocimeter. Microvasc. Res. 34:223-230.
37. HOUSE, S. D., and H. LIPOWSKY, 1987. Leukocyte-endothelium adhesion: Microhemodynamics in mesentery of the cat. Microvasc. Res. 34:363-379.
38. ASAKO, H., R. F. WOLF, and D. N. GRANGER. 1993. Leukocyte adherence in rat mesenteric venules: effects of adenosine and methotrexate. Gastroenterology 104:31-37.
39. CHADWICK, U. S., and M. CAMILLERI. 1983. Pathophysiology of small intestinal function and the effect of Crohn's disease. In Inflammatory Bowel Disease. A. Keighley and A. Williams, editors. Churchill Livingstone, Edinburgh. 29-42.
40. KERN, F. 1973. Disappearance of deoxycholic acid after ileal resection. Gastroenterology 64:123-127.
41. CAMILLERI, M., R. MURPHY, C. CHEM, and V. S. CHADWICK. 1980. Dose related effects of chenodeoxycholic acid in the rabbit colon. Dig. Dis. Sci. 23:433-438.
42. LEUSCHNER, U., H. FISCHER, W. KURTZ, S. GÜDÜLTÜNA, K. HÜBNER, A. HELLSTERN, M. GATZE, and M. LEUSCHNER. 1989. Ursodeoxycholic acid in primary biliary cirrhosis: Results of a double blind trial. Gastroenterology 97:1268-1274.
43. KULLMANN, F., V. GROSS, J. RÜSCHOFF, H. ARNDT, W. BENDA, A. WINKLER VOV MOHRENFELS, and J. SCHÖLMERICH. 1997. Effect of ursodeoxycholic acid on the inflammatory activity of indomethacin-induced intestinal inflammation in rats. Z. Gastroenterol. 35:171-178.
44. GRANGER, D. N., M. B. GRISHAM, and P. R. KVIETYS. 1994. Mechanisms of microvascular injury. In Physiology of the gastrointestinal tract. 3rd edition. L. R. Johnson, editor. Raven Press, New York. 1693-1722.
45. FEDEROWSKI, T., G. SALEN, A. COLALLILO, G. S. TIRET, E. H. MOSBACH, and J. C. HALL. 1977. Metabolism of ursodeoxycholic acid in man. Gastroenterology 73:1131-1137.
46. RODA, E., A. RODA, C. SAMA, D. FESTI, G. MAZZELLA, R. ALDINI, and L. BARBARA. 1979. Effect of ursodeoxycholic acid administration on biliary lipid composition and bile acid kinetics in cholesterol gallstone patients. Dig. Dis. Sci. 24:123-128.
47. KISHINAKA M., A. UMEDA and S. KUROKI. 1994. High concentrations of conjugated bile acids inhibit bacterial growth of Clostridium perfringens and induce its extracellular cholylglycine hydrolase. Steroids 59:485-489.
48. HAYAKAWA, S. 1982. Microbial transformation of bile acids. A unified scheme for bile acid degradation, and hydroxylation of bile acids. Z Allgem. Mikrobiol. 22:309-326.
49. MACDONALD, J. A., G. SINGH, D. E. MAHONEY, and C. E. MEIER. 1978. Effect of pH on bile salt degradation by mixed fecal cultures. Steroids 32:245-256.
50. 2 and non-steroidal antiinflammatory drugs. Dig. Dis. Sci. 31:631-637.
51. ARNDT, H., PALITZSCH, K.-D., and J. SCHÖLMERICH. 1995. Leukocyte-endothelial cell adhesion in indomethacin-induced intestinal inflammation is correlated with fecal pH. Gastroenterology 108:A773 (abstract).