Exploring linkage of chromosome 18 markers and bipolar disease

Genetic Epidemiology

Volumn 14, Issue 6, 1997, Pages 623-627

  Durner, Martina ^a   Abreu, Paula ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Howard Hughes Medical Institute   (United States)

Author keywords

Bipolar disease; Chromosome 18; Independent male female recombination fraction; Linkage analysis; Parent of origin effect; Penetrance; Phenocopies

Indexed keywords

CHROMOSOME 18; COMPUTER SIMULATION; CONFERENCE PAPER; GENETIC LINKAGE; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; MANIC DEPRESSIVE PSYCHOSIS; PEDIGREE; PENETRANCE;

BIPOLAR DISORDER; CHROMOSOMES, HUMAN, PAIR 18; FATHERS; FEMALE; GENETIC HETEROGENEITY; GENETIC MARKERS; HUMANS; LINKAGE (GENETICS); MALE; MOTHERS; PEDIGREE; PENETRANCE; RECOMBINATION, GENETIC; SEX DISTRIBUTION;

EID: 0031470158     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:6<623::AID-GEPI12>3.0.CO;2-S     Document Type: Conference Paper

References (5)

1. Durner M, Greenberg DA, Hodge SE (1996): Phenocopies versus genetic heterogeneity: can we use phenocopy frequencies in linkage analysis to compensate for heterogeneity? Hum Hered 46:265-273.
2. Gershon ES, Badner JA, Detera-Wadleigh SD, Ferraro TN, Berrettini WH (1996): Maternal inheritance and chromosome 18 allele sharing in unilineal bipolar illness pedigrees. Am J Med Genet (Neuropsychiatr Genet) 67:202-207.
3. Hodge SE, Elston RC (1994): Lods, wrods, and mods: The interpretation of lod scores calculated under different models. Genet Epidemiol 11:329-342.
4. Stine OC, Xu J, Koskela R, McMahon FJ, Gschwend M, Friddle C, Clark CD, McInnis MG, Simpson SG, Breschel TS, Vishio E, Riskin K, Feilotter H, Chen E, Shen S, Folstein S, Meyers DA, Botstein D, Marr TG, DePaulo JR (1995): Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet 57:1384-1394.
5. Weissman MM, Boyd JH (1984): The epidemiology of affective disorders. In Post RM, Ballenger JC (eds): "Neurobiology of Mood Disorders." Baltimore: Williams & Wilkins, pp 60-75.