Prior segregation analysis and the power to detect linkage

Genetic Epidemiology

Volumn 14, Issue 6, 1997, Pages 755-760

  Atwood, Larry D ^a,c   Slifer, Susan H ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Robustness; Simulation

Indexed keywords

ACCURACY; CONFERENCE PAPER; GENE SEGREGATION; GENETIC LINKAGE; MODEL;

EID: 0031469588     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:6<755::AID-GEPI32>3.0.CO;2-N     Document Type: Conference Paper

References (8)

1. Atwood LD, Mitchell BD, Stowell NC (1995): Segregation and linkage analysis of the complex trait Q1. Genet Epidemiol 12:713-718.
2. Dizier M, Bonaiti-Pelle C, Clerget-Darpoux F (1993): Conclusions of segregation analysis for family data generated under two-locus models. Am J Hum Genet 53:1338-1346.
3. Elston RC (1989): Man bites dog? The validity of maximizing lod scores to determine mode of inheritance. Am J Med Genet 34:487-488.
4. Hasstedt SJ (1994): Pedigree Analysis Package, Revision 4.0. Department of Human Genetics, University of Utah.
5. Lander L, Kruglyak L (1995): Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
6. Lalouel JM, Rao DC, Morton NE, Elston RC (1983): A unified model for complex segregation analysis. Am J Hum Genet 35:816-826.
7. Vieland VJ, Hodge SE, Greenberg DA J (1992): Adequacy of single-locus approximations for linkage analysis of oligogenic traits. Genet Epidemiol 9:45-59.
8. Vieland VJ, Greenberg DA, Hodge SE (1993): Adequacy of single-locus approximations for linkage analysis of oligogenic traits. Hum Hered. 43:329-336.