Antibody response of Echinococcus granulosus infected mice: Protoscolex specific response during infection is associated with decreasing specific IgG1/IgG3 ratio as well as decreasing avidity

Parasite Immunology

Volumn 19, Issue 12, 1997, Pages 545-552

  Severi, Ma Angelica ^a   Ferragut, Gabriela ^a   Nieto, Alberto ^b  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Antibody avidity; E. granulosus; IgG subclasses; Protoscoleces antigen; Secondary hydatidosis in mice

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M;

ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; ECHINOCOCCOSIS; ECHINOCOCCUS GRANULOSUS; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; ECHINOCOCCUS GRANULOSUS; PROTOZOA;

EID: 0031468955     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.1997.d01-172.x     Document Type: Article

References (34)

1. Araj G.F., Matossian R.M. & Frayha G.J. (1977) The host response in secondary hydatidosis of mice. I. Circulating antibodies. Zeitschrift fur Parasitenkunde 52, 23-30
2. Bentancor A., Gonzalez S., Baz A., Borreli S. & Nieto A. (1996) Characterization of two monoclonal antibodies recognizing carbohydrates epitopes of E. granulosus protoscoleces and cyst membranes. Glycobiology 6, 765
3. Butterworth A., Dunne D., Fulford A., Capron M., Koch D., Ouma J. & Sturrock R. (1988) Immunity in human schistosomiasis mansoni: cross-reactive IgM and IgG2 anti-carhohydrate antibodies block the expression of immunity. Biochimie 70, 1053-1063
4. Cox D.A., Marshall-Clarke S. & Dixon J.B. (1989) Activation of normal murine B cells by Echinococcus granulosus. Immunology 67, 16-20
5. Craig P.S. (1988) Immunobiology of human hydatid disease. ISI Atlas of Science: Immunobiology 95, 95-100
6. Dempster R.P., Harrison G.B., Berridge M.V. & Heath D.D. (1992) Echinococcus granulosus: use of an intermediate host mouse model to evaluate sources of protective antigens and a role for antibody in the immune response. International Journal for Parasitology 22, 435-441
7. Dresser D. (1986) In: Handbook of Experimental Immunology, D.M. Weir, ed, pp. 8.1-8.21, Blackwell Science, Oxford
8. Dunne D.W. (1990) Schistosome Carbohydrates. Parasitology Today 6, 45-68
9. El Bouhdidi A., Truyens C., Rivera M.A., Bazin H. & Carlier Y. (1994) Trypanosoma cruzi infection in mice induces a polyisotypic hyper-gammaglobulinaemia and parasite-specific response involving high IgG2a concentrations and highly avid IgG1 antibodies. Parasite Immunology 16, 69-76
10. Farr A. & Nakane P. (1981) Immunochemistry with enzyme labelled antibodies: a brief review. Journal of Immunological Methods 47, 129-144
11. Ferragut G. & Nieto A. (1996) Antibody response of Echinococcus granulosus infected mice: recognition of glucidic and peptidic epitopes and lack of avidity maturation. Parasite Immunology 18, 393-402
12. Haralabidis S., Karagouni E., Frydas S. & Dotsika E. (1995) Immunoglobulin and cytokine profile in murine secondary hydatidosis. Parasite Immunology 17, 625-630
13. Heath D.D. (1970) The development of Echinococcus granulosus larvae in laboratory animals. Parasitology 60, 449-456
14. Heath D.D. (1986) Immunobiology of Echinococcus infections. In: The Biology of Echinococcus and Hydatid Disease, R.C.A. Thompson, ed, pp. 164-182. George Allen & Unwin, London
15. Hernández A. & Nieto A. (1994) Induction of protective immunity against murine secondary hydatidosis. Parasite Immunology 16, 537-544
16. Hudson L. & Hay F.C. (1989) In: Practical Immunology, Hudson & Hay, ed, pp. 12-14, Blackwell Science, London
17. Janssen D., Osuna A., Lazuen J. & De Rycke P.H. (1992) Comparative cytotoxicity of secondary hydatid cysts, protoscoleces, and in vitro developed microcysts of Echinococcus granulosus. Journal of Helminthology 66, 124-131
18. Laemmli U.K. (1970) Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227, 680-685
19. Langley J.G. & Dunne D.W. (1992) Temporal variation in the carbohydrate and peptide surface epitopes in antibody dependent, eosinophil-mediated killing of Schistosoma mansoni schistosomula. Parasite Immunology 14, 185-200
20. Lightowlers M.W. (1990) Immunobiology and molecular biology of Echinococcus infections. International Journal of Parasitology 20, 471-478
21. Liu D., Lightowlers M.W. & Rickard M.D. (1992) Examination of murine antibody response to secondary hydatidosis using ELISA and immunoelectrophoresis. Parasite Immunology 14, 239-248
22. Maizels R.M., Bundy D.A.P., Selkirk M.E., Smith D.F. & Anderson R.M. (1993) Immunological modulation and evasion by helminth parasites in human populations. Nature 365, 797-805
23. Malvano R., Boniolo A., Dovis M. & Zannino M. (1982) ELISA for antibody measurement: aspects related to data expression. Journal of Immunological Methods 48, 51-55
24. Mazza G., Dunne D.W. & Butterworth A. (1990) Antibody isotype responses to the Schistosoma mansoni schistosomulum in the CBA/N mouse induced by different stages of parasite life cycle. Parasite Immunology 12, 529-543
25. Míguez M., Baz A. & Nieto A. (1996) Carbohydrates on the surface of Echinococcus granulosus protoscoleces are immunodominant in mice. Parasite Immunology 18, 559-569
26. Mond J.J., Lees A. & Snapper C.M. (1995) T cell-independent antigens type 2. Annual Review of Immunology 13, 655-692
27. Perlmutter R.M., Hansburg D., Briles D.E., Nicolotti A. & Davie M.J. (1978) Subclass restriction of murine anti-carbohydrate antibodies. Journal of Immunology 121, 566-572
28. Pullen G.R., Fitzgerald M.G. & Hosking C.S. (1986) Antibody avidity determination by ELISA using thiocyanate elution. Journal of Immunological Methods 86, 83-87
29. Sterla S., Ljungström I. & Nieto A. (1997) Modified ELISA for hydatid serodiagnosis: the potential of periodate treatment and phosphorylcholine inhibition. Serodiagnosis and Immunotherapy in Infections Disease 8, 145-148
30. Tijssen P. (1985) In: Laboratory Techniques in Biochemistry and Molecular Biology, R.H. Burdon & P.H. van Knippenberg eds, 15, pp. 236-241, Elsevier Science, Oxford
31. Towbin H., Stahelin T. & Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Proceedings of the National Academy of Sciences, USA 76, 4350-4354
32. + cells T cells subsets. Proceedings of the National Academy of Sciences, USA 91, 18-22
33. Velupillai P, Sypek J. & Harn D.A. (1996) IL-12 and IL-10 and Gamma Interferon regulate polyclonal and ligand-specific expansion of murine B-1 cells. Infection and Immunity 64, 4557-4560
34. Woodward M.P., Young W.W. & Bloodgood R.A. (1985) Detection of monoclonal antibodies specific for carbohydrate epitopes using periodate oxidation. Journal of Immunological Methods 78, 143-153