The human cornea has a high incidence of acquired chromosome abnormalities

Human Genetics

Volumn 101, Issue 1, 1997, Pages 26-29

  Pettenati, Mark J ^a   Sweatt, Andrew J ^a   Lantz, Patrick ^a   Stanton, Constance A ^a   Reynolds, James ^b   Rao, P Nagesh ^a   Davis, Richard M ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b Shodair   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANEUPLOIDY; ARTICLE; CHROMOSOME ABERRATION; CORNEA; EMBRYO; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; PRIORITY JOURNAL;

ABNORMALITIES; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANEUPLOIDY; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CORNEA; CORNEAL DYSTROPHIES, HEREDITARY; FEMALE; FIBROBLASTS; FUCHS' ENDOTHELIAL DYSTROPHY; HUMANS; INFANT; INFANT, NEWBORN; KARYOTYPING; KERATOCONUS; MALE; MIDDLE AGED;

EID: 0031468805     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390050580     Document Type: Article

References (19)

1. Bardi G, Johansson B, Pandis N, Heim S, Mandahl N, Hagerstrand I, Holmin T, et al (1992) Trisomy 7 in nonneoplastic focal steatosis of the liver. Cancer Genet Cytogenet 63 : 22-24
2. Casalone R, Granata Casalone P, Minelli E, Portentoso P, Righi R, Meroni E, Giudici A, et al (1992) Significance of the clonal and sporadic chromosome abnormalities in non-neoplastic renal tissue. Hum Genet 90 : 71-78
3. Emanuel A, Szucs S, Weier H-UG, Kovacs G (1992) Clonal aberration of chromosomes X, Y, 7 and 10 in normal kidney tissue of patients with renal cell tumors. Genes Chrom Cancer 4 : 75-77
4. Hassell JR, et al (1992) Biosynthesis of stromal matrix proteoglycans and basement membrane components by human corneal fibroblasts. Invest Ophthalmol Vis Sci 33 : 547-557
5. Herrmann ME, Lalley PA (1992) Significance of trisomy 7 in thyroid tumors. Cancer Genet Cytogenet 62 : 144-149
6. Jakobiec FA (1988) Corneal tumors. In: Kaufman HE, Barron BA, McDonald MB, Waltman SR (eds) The cornea. Churchill Livingston, New York, pp 563-598
7. Jester JV, Rodrigues MM, Herman IM (1987) Characterization of avascular corneal wound healing fibroblasts: new insights into the myofibroblast. Am J Pathol 127 : 40-48
8. Johansson B, Heim S, Mandahl N, Mertens F, Mitelman F (1993) Trisomy 7 in nonneoplastic cells. Genes Chrom Cancer 6 : 199-205
9. King CM, Gillespie ES, McKenna PG, Barnett YA (1994) An investigation of mutation as a function of age in humans. Mutat Res 316 : 79-90
10. Lindor NM, Devries EMG, Michels VV, Schad CR, Jalal SM, Donovan KM, Smithson WA, et al (1996) Rothmund-Thomson syndrome in sibling: evidence for acquired in vivo mosaicism. Clin Genet 49 : 124-129
11. Martin RH, Rademaker A (1990) The frequency of aneuploidy among individual chromosomes in 6,821 human sperm chromosome complements. Cytogenet Cell Genet 53 : 103-107
12. Pettenati MJ, Rao PN, Schnell S, Hayworth-Hodge R, Lantz PE, Geisinger KR (1995) Gender identification of dried human bloodstains using fluorescence in situ hybridization. J Forensic Sci 40 : 883-885
13. Prieur M, Achkar WA1, Aurias A, Couturier J, Dutrillaux AM, Dutrillaux B, Flüry-Herard A, et al (1988) Acquired chromosome rearrangements in human lymphocytes: effect of aging. Hum Genet 79 : 147-150
14. Ramsey MJ, Moore DH, Briner JF, Lee DA, Olsen LA, Senft JR, Tucker JD (1995) The effects of age and lifestyle factors on the accumulation of cytogenetic damage as measured by chromosome painting. Mutat Res 338 : 95-106
15. Scappaticci S, Capra E, Cortinovis M, Cortinovis R, Arbustini E, Diegoli M, Fraccaro M (1994) Cytogenetic studies in venous tissue from patients with varicose veins. Cancer Genet Cytogenet 75 : 26-30
16. Snedecor GW, Cochran WG (1967) Statistical methods, 6th edn. Iowa State University Press, Ames
17. Streilein JW (1996) Ocular immune privilege and the Faustian dilemma - the Proctor lecture. Invest Ophthalmol Vis Sci 37 : 1940-1950
18. Townsend WM (1988) Congenital anomalies of the cornea. In: Kaufman HE, Barron BA, McDonald MB, Waltman SR (eds) The cornea. Churchill Livingston, New York, pp 333-360
19. Wilson FM (1994) Congenital anomalies of the cornea and conjunctiva. In: Smolin G, Thorft RA (eds) The cornea: scientific foundations and clinical practice, 3rd edn. Little, Brown, New York, pp 550-551