Mast cell tryptase and asthma

Mediators of Inflammation

Volumn 6, Issue 5-6, 1997, Pages 311-317

  Zhang, M Q ^a,b   Timmerman, H ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Asthma; H1 antagonists; Histamine; Mast cells; Tryptase; Tryptase inhibitors

Indexed keywords

ANTIASTHMATIC AGENT; BABIM; BRADYKININ; CETIRIZINE; CHLORPHENIRAMINE; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; LORATADINE; METIAMIDE; N (1 HYDROXY 2 NAPHTHOYL)ARGINYLPROLINAMIDE; OXATOMIDE; PEPTIDE HISTIDINE METHIONINE; PROTEINASE INHIBITOR; TRYPTASE; TRYPTASE INHIBITOR; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BRONCHOSPASM; CLINICAL TRIAL; ENZYME INHIBITION; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MAST CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0031468266     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629359791433     Document Type: Article

References (49)

1. 1 receptor antagonists. In: Wolff ME (ed.) Burger's Medicinal Chemistry and Drug Discovery (5th Ed), Vol. 5: Therapeutic Agents. New York: John Wiley, 1997; 495-559.
2. Schwartz LB, Lewis RA, Austen KF. Tryptase from human pulmonary mast cells. Purification and characterization. J Biol Chem 1981; 256: 11939-11943.
3. Craig SS, Scheimer NM, Schwartz LB. Ultrastructural analysis of maturing human T and TC mast cells in situ. Lab Invest 1989; 60: 147-157.
4. Irani AA, Scheimer NM, Craig SS, DeBlois G, Schwartz LB. Two types of human mast cells that have distinct neutral protease compositions. Proc Natl Acad Sci USA 1986; 83: 4464-4468.
5. Schwartz LB. Laboratory assessment of immediate hypersensitivity and anaphylaxis - use of tryptase as marker of mast cell-dependent events. Immunol Allergy Clin N Am 1994; 14: 339-349.
6. Smith TJ, Hougland MW, Johnson DA. Human lung tryptase. Purification and characterization. J Biol Chem 1984; 259: 11046-11051.
7. Alter SC, Kramps JA, Janoff AA, Schwartz LB. Interactions of human mast cell tryptase with biological protease inhibitors. Arch Biochem Biophys 1990; 276: 26-31.
8. Schwartz LB, Bradford TR. Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer. J Biol Chem 1986; 261: 7372-7379.
9. Harvima IT, Schechter NM, Harvima RJ, Fräki JE. Human skin tryptase: purification, partial characterization and comparison with human lung tryptase. Biochim Biophys Acta 1988; 957: 71-80.
10. 2-terminal sequence, immuno-cytochemical localization, and specificity with prohormone and fluorogenic substrates. J Biol Chem 1987; 262: 1363-1373.
11. Butterfield JH, Weiler DA, Hunt LW, Wynn SR, Roche PC. Purification of tryptase from a human mast cell line. J Leukocyte Biol 1990; 47: 409-419.
12. Schwartz LB, Bradford TR, Lee DC, Chlebowski JF. Immunologic and physicochemical evidence for conformational changes occurring on conversion of human mast cell tryptase from active tetramer to inactive monomer Production of monoclonal antibodies recognizing active tryptase. J Immunol 1990; 144: 2304-2311.
13. Johnson DA, Barton GJ. Mast cell tryptases: examination of unusual characteristics by multiple sequence alignment and molecular modeling. Protein Sci 1992; 1: 370-373.
14. Schwartz LB. Tryptase: a mast cell serine protease. Meth Enzymol 1994; 244: 88-100.
15. Miller JS, Moxley G, Schwartz LB. Cloning and characterization of a second complementary DNA for human tryptase. J Clin Invest 1990; 86: 864-870.
16. Vanderslice P, Ballinger SM, Tam EK, Goldstein SM, Craik CS, Caughey GH. Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family. Proc Natl Acad Sci USA 1990; 87: 3811-3815.
17. Little SS, Johnson DA. Human mast cell tryptase isoforms: separation and examination of substrate-specificity differences. Biochem J 1995; 307: 341-346.
18. McEuen AR, He S, Brander ML, Walls AF. Guinea pig lung tryptase. Localisation to mast cells and characterisation of the partially purified enzyme. Biochem Pharmacol 1996; 52: 331-340.
19. Pallaoro M, Gambacurta A, Fiorucci L, Mignogna G, Barra D, Ascoli F. cDNA cloning and primary structure of tryptase from bovine mast cells, and evidence for the expression of bovine pancreatic trypsin inhibitor mRNA in the same cells. Eur J Biochem 1996; 237: 100-105.
20. Vanderslice P, Craik CS, Nadel JA, Caughey GH. Molecular cloning of dog mast cell tryptase and a related protease: structural evidence of a unique mode of serine protease activation. Biochemistry 1989; 28: 4148-4155.
21. Braganza VJ, Simmons WH. Tryptase from rat skin: purification and properties. Biochemistry 1991; 30: 4997-5007.
22. Chu W, Johnson DA, Musich PR. Molecular cloning and characterization of mouse mast cell chymases. Biochim Biophys Acta 1992; 1121: 83-87.
23. Murakumo Y, Ide H, Itoh H, et al. Cloning of the cDNA encoding mast cell tryptase of Mongolian gerbil, Meriones unguiculatus, and its preferential expression in the intestinal mucosa. Bioccem J 1995; 309: 921-926.
24. Tanaka T, McRae BJ, Cho K, et al. Mammalian tissue trypsin-like enzymes. Comparative reactivities of human skin tryptase, human lung tryptase, and bovine trypsin with peptide 4-nitroanilide and thioester substrates. J Biol Chem 1983; 258: 13552-1355.
25. Schwartz LB, Yumginger JW, Miller JS, Bokhari R, Dull D. The time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis. J Clin Invest 1989; 83: 1551-1555.
26. Tsubaki T, Iikura Y, Saito H, et al. Changes in histamine/tryptase levels in skin chambers - application for clinical evaluation of atopic dermatitis. Int Arch Allergy Immunol 1992; 99: 459-462.
27. Schwartz LB. Cellular inflammation in asthma: neutral proteases of mast cells. Am Rer Respir Dis 1992; 145: S18-S21.
28. Fischer AR, Rosenberg MA, Lilly CM, et al. Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. J Allergy Clin Immunol 1994; 94: 1046-1056.
29. Polosa R, Ng WH, Crimi N, et al. Release of mast-cell-derived mediators after endobronchial adenosine challenge in asthma. Am J Resp Crit Care Med 1995; 151: 624-629.
30. Fahy JV, Kim KW, Liu J, Boushey HA. Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol 1995; 95: 843-852.
31. Sekizawa K, Caughey GH, Lazarus SC, Gold WM, Nadel JA. Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs. J Clin Invest 1989; 83: 175-179.
32. Ferguson AC, Whitelaw M, Brown H. Correlation of bronchial eosinophil and mast cell activation with bronchial hyperresponsiveness in children with asthma. J Allergy Clin Immunol 1992; 90: 609-613.
33. Tam EK, Caughey GH. Degradation of airway neuropeptides by human lung tryptase. Am J Respir Cell Mol Biol 1990; 3: 27-32.
34. Lilly CM, Martins MA, Drazen JM. Peptidase modulation of vasoactive intestinal peptide pulmonary relaxation in tracheal superfused guinea pig lungs. J Clin Invest 1993; 91: 235-243.
35. Franconi GM, Graf PD, Lazarus SC, Nadel JA, Caughey GH. Mast cell tryptase and chymase reverse airway smooth muscle relaxation induced by vasoactive intestinal peptide in the ferret. J Pharmacol Exp Ther 1989; 24: 133-137.
36. Proud D, Siekierski ES, Bailey GS. Identification of human lung mast cell kininogenase as tryptase and relevance of tryptase kininogenase activity. Biochem Pharmacol 1988; 37: 1473-1480.
37. Walls AF, Bennett AR, Sueiras-Diaz J, Olsson H. The kininogenase activity of human mast cell tryptase. Biochem Soc Transaction 1992; 20: 260s.
38. Smith PL, Kagey-Sobotka A, Bleecker ER, et al. Physiologic manifestations of human anaphylaxis. J Clin Invest 1980; 66: 1072-1080.
39. Brown JK, Tyler CL, Jones CA, Ruoss SJ, Hartmann T, Caughey GH. Tryptase, the dominant secretory granular protein in human mast cells, is a potent mitogen for cultured dog tracheal smooth muscle cells. Am J Respir Cell Mol Biol 1995; 13: 227-236.
40. Brown JK, Tyler CL, Jones CA, Ruoss SJ, Hartmann T, Caughey GH. Tryptase-induced mitogenesis in airway smooth muscle cells. Potency, mechanisms, and interactions with other mast cell mediators. Chest 1995; 107: 95S-96S.
41. Cairns JA, Walls AF. Mast cell tryptase is a mitogen for epithelial cells. Stimulation of IL-8 production and intercellular adhesion molecule-1 expression. J Immunol 1996; 156: 275-283.
42. Walls AF, He S, Teran LM, et al. Granulocyte recruitment by human mast cell tryptase. Int Arcb Allergy Immunol 1995; 107: 372-373.
43. Patella V, de Crescenzo G, Marino O, Spadaro G, Genovese A, Marone G. Oxatomide inhibits the release of proinflammatory mediators from human basophils and mast cells. Int Arch Allergy Immunol 1996; 111: 23-29.
44. Greiff L, Persson CGA, Svensson C, Enander I, Andersson M. Loratadine reduces allergen-induced mucosal output of alpha(2)-macroglobulin and tryptase in allergic rhinitis. J Allergy Clin Immunol 1995; 96: 97-103.
45. Molinari JF, Scuri M, Moore WR, Clark J. Tanaka R, Abraham WM. Inhaled tryptase causes bronchoconstriction in sheep via histamine release. Am J Respir Crit Care Med 1996; 154: 649-653.
46. Molinari JF, Moore WR, Clark J, Tanaka R, Butterfield JH, Abraham WM. Role of tryptase in immediate cutaneous responses in allergic sheep. J Appl Physiol 1995; 79: 1966-1970.
47. Clark JM, Abraham WM, Fishman CE, et al. Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep. Am J Respir Crit Care Med 1995; 152: 2076-2083.
48. Gaughey GH, Raymond WW, Bacci E, Lombardy RJ, Tidwell RR. Bis(5-amidino-2-benzimidazolyl)methane and related amidines are potent, reversible inhibitors of mast cell tryptases. J Pharmacol Exp Ther 1993; 264: 676-682.
49. Ghosh SK, De Vos C, McIlroy I, Patel KR. Effect of cetirizine on exercise-induced asthma. Thorax 1991; 46: 242-244.