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Volumn 6, Issue 5-6, 1997, Pages 295-302

Neurovascular damage in experimental allergic encephalomyelitis: A target for pharmacological control

Author keywords

Blood brain barrier; Cyclosporin; Glucocorticoids; MK 801; N methyl D aspartate receptor; Polyamines

Indexed keywords

ALBUMIN; CYCLOSPORIN A; DEXAMETHASONE; DIZOCILPINE; GLUCOCORTICOID; HORSERADISH PEROXIDASE; MANNITOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PRAZOSIN; TUFTSIN;

EID: 0031467484     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629359791415     Document Type: Review
Times cited : (10)

References (103)
  • 1
    • 0018847124 scopus 로고
    • The vascular system of the cerebral cortex
    • Bar T. The vascular system of the cerebral cortex. Adv Anat Embryo Cell Biol 1980; 59: 1-62.
    • (1980) Adv Anat Embryo Cell Biol , vol.59 , pp. 1-62
    • Bar, T.1
  • 2
    • 0027319870 scopus 로고
    • Pericyte physiology
    • Shepro D, Morel NML. Pericyte physiology FASEB J 1993; 7: 1031-1038.
    • (1993) FASEB J , vol.7 , pp. 1031-1038
    • Shepro, D.1    Morel, N.M.L.2
  • 3
    • 0011229610 scopus 로고
    • The blood-brain barrier: A modified tight epithelium
    • Suckling AJ, Rumsby MG, Bradbury MWB, eds. Chichester: Ellis Horwood
    • Crone C. The blood-brain barrier: a modified tight epithelium. In: Suckling AJ, Rumsby MG, Bradbury MWB, eds. The Blood-Brain Barrier in Health and Disease. Chichester: Ellis Horwood, 1986; 17-40.
    • (1986) The Blood-Brain Barrier in Health and Disease , pp. 17-40
    • Crone, C.1
  • 4
    • 0022775491 scopus 로고
    • The blood-brain barrier
    • Goldstein GW, Betz AL. The blood-brain barrier. Sci Am 1986; 255: 70-79.
    • (1986) Sci Am , vol.255 , pp. 70-79
    • Goldstein, G.W.1    Betz, A.L.2
  • 5
    • 0023755518 scopus 로고
    • Endothelial cell astrocyte interactions. A cellular model of the blood-brain barrier
    • Goldstein GW. Endothelial cell astrocyte interactions. A cellular model of the blood-brain barrier. Ann NY Acad Sci 1988; 529: 31-39.
    • (1988) Ann NY Acad Sci , vol.529 , pp. 31-39
    • Goldstein, G.W.1
  • 6
    • 0002051908 scopus 로고
    • Development of the blood-brain barrier
    • Greenwood J, Begley DJ, Segal MB, eds. New York: Plenum Press
    • Engelbardt B, Risau W. Development of the blood-brain barrier. In: Greenwood J, Begley DJ, Segal MB, eds. New Concepts of a Blood Brain Barrier New York: Plenum Press, 1995; 11-31.
    • (1995) New Concepts of a Blood Brain Barrier , pp. 11-31
    • Engelbardt, B.1    Risau, W.2
  • 7
    • 0023885278 scopus 로고
    • Blood-brain barrier (BBB). Review from morphological aspect
    • Cervos-Navarro J, Kannuki S, Nakagawa Y. Blood-brain barrier (BBB). Review from morphological aspect. Histol Histopath 1988; 3: 203-213.
    • (1988) Histol Histopath , vol.3 , pp. 203-213
    • Cervos-Navarro, J.1    Kannuki, S.2    Nakagawa, Y.3
  • 8
    • 0018855966 scopus 로고
    • Polarity of the blood-brain barrier: Distribution of enzymes between the luminal and antiluminal membranes of the brain capillary endothelial cells
    • Betz AL, Firth JA, Goldstein GW. Polarity of the blood-brain barrier: distribution of enzymes between the luminal and antiluminal membranes of the brain capillary endothelial cells. Brain Res 1980; 192: 17-28.
    • (1980) Brain Res , vol.192 , pp. 17-28
    • Betz, A.L.1    Firth, J.A.2    Goldstein, G.W.3
  • 9
    • 0020668897 scopus 로고
    • Enzyme cytochemistry of the cerebral microvessel wall
    • Kreutzberg GW, Tóth L. Enzyme cytochemistry of the cerebral microvessel wall. Acta Neuropathol 1983; 8: 35-41.
    • (1983) Acta Neuropathol , vol.8 , pp. 35-41
    • Kreutzberg, G.W.1    Tóth, L.2
  • 10
    • 0021919062 scopus 로고
    • The blood-brain barrier in vitro: Ten years of research on microvessels isolated from the brain
    • Joó F. The blood-brain barrier in vitro: ten years of research on microvessels isolated from the brain. Neurochem Int 1985; 7: 1-25.
    • (1985) Neurochem Int , vol.7 , pp. 1-25
    • Joó, F.1
  • 11
    • 0002634361 scopus 로고
    • The dependency of influx across the blood-brain barrier on blood flow and the apparent flow-independence of glucose influx during stress
    • Greenwood J. Begley DJ, Segal MB, eds. New York: Plenum Press
    • Fernstermacher JD, Wei L, Acuff V, et al. The dependency of influx across the blood-brain barrier on blood flow and the apparent flow-independence of glucose influx during stress. In: Greenwood J. Begley DJ, Segal MB, eds. New Concepts of a Blood-Brain Barrier. New York: Plenum Press, 1995; 89-101.
    • (1995) New Concepts of a Blood-Brain Barrier , pp. 89-101
    • Fernstermacher, J.D.1    Wei, L.2    Acuff, V.3
  • 12
    • 0000596384 scopus 로고
    • Studies on an immortalized brain endothelial cell line: Characterisation, permeability and transport
    • Greenwood J, Begley DJ, Segal MB, eds. New York: Plenum Press
    • Abbott NJ, Courand PO, Roux F, Begley DJ. Studies on an immortalized brain endothelial cell line: characterisation, permeability and transport. In: Greenwood J, Begley DJ, Segal MB, eds. New Concepts of a Blood Brain Barrier. New York: Plenum Press, 1995; 239-249.
    • (1995) New Concepts of a Blood Brain Barrier , pp. 239-249
    • Abbott, N.J.1    Courand, P.O.2    Roux, F.3    Begley, D.J.4
  • 13
    • 0020314516 scopus 로고
    • Problems of delivery of drugs to the brain
    • Bodor N, Brewster M. Problems of delivery of drugs to the brain. Pharmacol Ther 1983; 19: 337-386.
    • (1983) Pharmacol Ther , vol.19 , pp. 337-386
    • Bodor, N.1    Brewster, M.2
  • 14
    • 0022559194 scopus 로고
    • Specialised properties and solute transport in brain capilliaries
    • Betz AL, Goldstein GW. Specialised properties and solute transport in brain capilliaries. Ann Rev Physio 1986; 48: 142-250.
    • (1986) Ann Rev Physio , vol.48 , pp. 142-250
    • Betz, A.L.1    Goldstein, G.W.2
  • 15
    • 0023943054 scopus 로고
    • Interactions between the blood-brain barrier and endogenous peptides: Emerging clinical implications
    • Banks WA, Kastin AJ. Interactions between the blood-brain barrier and endogenous peptides: emerging clinical implications. Am J Med Sci 1988; 295: 459-465.
    • (1988) Am J Med Sci , vol.295 , pp. 459-465
    • Banks, W.A.1    Kastin, A.J.2
  • 17
    • 6844230295 scopus 로고
    • The blood-central nervous system barrier in acute experimental allergic encephalomyelitis
    • Suckling AJ, Rumsby MG, Bradbury MWB. eds. Chichester: Ellis Horwood
    • Lam DKC. The blood-central nervous system barrier in acute experimental allergic encephalomyelitis. In: Suckling AJ, Rumsby MG, Bradbury MWB. eds. The Blood-Brain Barrier in Health and Disease. Chichester: Ellis Horwood, 1986; 17-40.
    • (1986) The Blood-Brain Barrier in Health and Disease , pp. 17-40
    • Lam, D.K.C.1
  • 18
    • 78651010946 scopus 로고
    • Immunity to homologous grafted skin III. The fate of skin homogratts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye
    • Medawar PB. Immunity to homologous grafted skin III. The fate of skin homogratts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Br J Exp Pathol 1948; 29: 58-69.
    • (1948) Br J Exp Pathol , vol.29 , pp. 58-69
    • Medawar, P.B.1
  • 19
    • 0024566659 scopus 로고
    • Differential expression of guinea pig class II major histocompatibility complex antigens on vascular endothelial cells in vitro and in experimental allergic encephalomyelitis
    • Wilcox CE, Baker D, Butter C, Willoughby DA, Turk JL. Differential expression of guinea pig class II major histocompatibility complex antigens on vascular endothelial cells in vitro and in experimental allergic encephalomyelitis. Cell Immunol 1989; 120: 82-91.
    • (1989) Cell Immunol , vol.120 , pp. 82-91
    • Wilcox, C.E.1    Baker, D.2    Butter, C.3    Willoughby, D.A.4    Turk, J.L.5
  • 20
    • 0026567373 scopus 로고
    • Adhesion molecules on murine brain microvascular endothelial cells: Expression and regulation of ICAM-1 and Lgp55
    • Fabry Z, Waldschmidt MM, Hendrickson DK, et al. Adhesion molecules on murine brain microvascular endothelial cells: expression and regulation of ICAM-1 and Lgp55. J Neuroimmunol 1992; 36: 1-11.
    • (1992) J Neuroimmunol , vol.36 , pp. 1-11
    • Fabry, Z.1    Waldschmidt, M.M.2    Hendrickson, D.K.3
  • 21
    • 0001370778 scopus 로고
    • Experimental autoimmune (allergic) encephalomyelitis: Induction, pathogenesis and suppression
    • Meischer PA, Mueller-Eberhard HJ, eds. New York: Grune & Stratton
    • Paterson PY. Experimental autoimmune (allergic) encephalomyelitis: induction, pathogenesis and suppression. In: Meischer PA, Mueller-Eberhard HJ, eds. Textbook of Immunopathology. New York: Grune & Stratton, 1976; 179-213.
    • (1976) Textbook of Immunopathology , pp. 179-213
    • Paterson, P.Y.1
  • 22
    • 0020446988 scopus 로고
    • Acute experimental autoimmune encephalomyelitis in mice. 1. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitisation and increased vascular permeability of the central nervous system
    • Linthicum DS, Munoz JJ, Blaskett A. Acute experimental autoimmune encephalomyelitis in mice. 1. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitisation and increased vascular permeability of the central nervous system. Cell Immunol 1982; 73: 299-310.
    • (1982) Cell Immunol , vol.73 , pp. 299-310
    • Linthicum, D.S.1    Munoz, J.J.2    Blaskett, A.3
  • 23
    • 0019978389 scopus 로고
    • Effects of histamine on brain capillaries: Fine structural and immunohistochemical studies after intracarotid infusion
    • Dux E, Joo F. Effects of histamine on brain capillaries: fine structural and immunohistochemical studies after intracarotid infusion. Exp Brain Res 1982; 47: 252-258.
    • (1982) Exp Brain Res , vol.47 , pp. 252-258
    • Dux, E.1    Joo, F.2
  • 24
    • 0024308205 scopus 로고
    • Brain and spinal cord levels of histamine in Lewis rats with acute experimental autoimmune encephalomyelitis
    • Orr EL, Stanley NC. Brain and spinal cord levels of histamine in Lewis rats with acute experimental autoimmune encephalomyelitis. J Neurochem 1989; 53: 111-118.
    • (1989) J Neurochem , vol.53 , pp. 111-118
    • Orr, E.L.1    Stanley, N.C.2
  • 25
    • 0021340329 scopus 로고
    • Modification of clinical and histopathologic expression of experimental allergic encephalomyelitis by a vasoactive amine antagonist - Cyproheptidine
    • Waxman FJ, Taguiam JM, Whitacre CC. Modification of clinical and histopathologic expression of experimental allergic encephalomyelitis by a vasoactive amine antagonist - cyproheptidine. Cell Immunol 1984; 85: 82-93.
    • (1984) Cell Immunol , vol.85 , pp. 82-93
    • Waxman, F.J.1    Taguiam, J.M.2    Whitacre, C.C.3
  • 26
    • 0021196056 scopus 로고
    • A longitudinal study of the prostaglandin content of central nervous system tissues from guinea pigs with acute experimental encephalomyelitis
    • Bolton C, Gordon D, Turk JL. A longitudinal study of the prostaglandin content of central nervous system tissues from guinea pigs with acute experimental encephalomyelitis. Int J Immunopharmac 1984; 6: 155-161.
    • (1984) Int J Immunopharmac , vol.6 , pp. 155-161
    • Bolton, C.1    Gordon, D.2    Turk, J.L.3
  • 27
    • 0022630987 scopus 로고
    • A study of the prostaglandin and thromboxane content of the central nervous tissues with the development of chronic relapsing allergic encephalomyelitis
    • Bolton C, Parker D, McLeod J, Turk JL. A study of the prostaglandin and thromboxane content of the central nervous tissues with the development of chronic relapsing allergic encephalomyelitis. J Neuroimmunol 1986; 10: 201-208.
    • (1986) J Neuroimmunol , vol.10 , pp. 201-208
    • Bolton, C.1    Parker, D.2    McLeod, J.3    Turk, J.L.4
  • 28
    • 0021262858 scopus 로고
    • Prostaglandin levels in cerebrospinal fluid from multiple sclerosis patients in remission and relapse
    • Bolton C, Turner AM, Turk JL, Prostaglandin levels in cerebrospinal fluid from multiple sclerosis patients in remission and relapse. J Neuroimmunol 1984; 6: 151-159.
    • (1984) J Neuroimmunol , vol.6 , pp. 151-159
    • Bolton, C.1    Turner, A.M.2    Turk, J.L.3
  • 30
    • 0024411745 scopus 로고
    • Indomethacin augments in vitro proliferative responses of Lewis rat lymphocytes to myelin basic protein - Implications for experimental allergic encephalomyelitis
    • Mannie MD, Pope L, Paterson PY. Indomethacin augments in vitro proliferative responses of Lewis rat lymphocytes to myelin basic protein - implications for experimental allergic encephalomyelitis. Cell Immunol 1989; 121: 196-212.
    • (1989) Cell Immunol , vol.121 , pp. 196-212
    • Mannie, M.D.1    Pope, L.2    Paterson, P.Y.3
  • 31
    • 0042244337 scopus 로고
    • Interleukin-1 and tumor necrosis factor/cachectin increase endothelial permeability in vitro
    • Henning B, Goldblum S, McClain C. Interleukin-1 and tumor necrosis factor/cachectin increase endothelial permeability in vitro. J Leukoc Biol 1987; 42: 551.
    • (1987) J Leukoc Biol , vol.42 , pp. 551
    • Henning, B.1    Goldblum, S.2    McClain, C.3
  • 32
    • 0024309730 scopus 로고
    • Tumour necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins
    • Brett J, Gerlach H, Nawroth P, Steinberg S, Godman G, Stern D. Tumour necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins. J Exp Med 1989; 169: 1977-1991.
    • (1989) J Exp Med , vol.169 , pp. 1977-1991
    • Brett, J.1    Gerlach, H.2    Nawroth, P.3    Steinberg, S.4    Godman, G.5    Stern, D.6
  • 33
    • 0025999081 scopus 로고
    • Human tumor necrosis factor-α augments experimental allergic encephalomyelitis in rats
    • Kuroda Y, Shimamoto Y. Human tumor necrosis factor-α augments experimental allergic encephalomyelitis in rats. J Neuroimmunol 1991; 34: 159-164.
    • (1991) J Neuroimmunol , vol.34 , pp. 159-164
    • Kuroda, Y.1    Shimamoto, Y.2
  • 34
    • 0025854496 scopus 로고
    • Cytokines in the central nervous system of mice during chronic relapsing allergic encephalomyelitis
    • Baker D, O'Neill JK, Turk JL. Cytokines in the central nervous system of mice during chronic relapsing allergic encephalomyelitis. Cell Immunol 1991; 134: 505-510.
    • (1991) Cell Immunol , vol.134 , pp. 505-510
    • Baker, D.1    O'Neill, J.K.2    Turk, J.L.3
  • 35
    • 0026596353 scopus 로고
    • In vivo relationship of tumour necrosis factor-α to blood-brain barrier damage in patients with active multiple sclerosis
    • Sharief MK, Thompson EJ. In vivo relationship of tumour necrosis factor-α to blood-brain barrier damage in patients with active multiple sclerosis. J Neuroimmunol 1992; 38: 27-34.
    • (1992) J Neuroimmunol , vol.38 , pp. 27-34
    • Sharief, M.K.1    Thompson, E.J.2
  • 36
    • 6844256373 scopus 로고
    • Immunomodulation of nitric oxide (NO) and its contribution to neurovascular permeability during experimental allergic encephalomyelitis (EAE)
    • Scott GS, Paul C, Whitehouse J, Williams KI, Bolton C. Immunomodulation of nitric oxide (NO) and its contribution to neurovascular permeability during experimental allergic encephalomyelitis (EAE). Inflamm Res 1995; 44: S223.
    • (1995) Inflamm Res , vol.44
    • Scott, G.S.1    Paul, C.2    Whitehouse, J.3    Williams, K.I.4    Bolton, C.5
  • 37
    • 0028360840 scopus 로고
    • Aminoguanidine, an inhibitor of inducible nitric oxide synthase ameliorates experimental autoimmune encephalomyelitis in SJL mice
    • Cross AH, Misko TP, Lin RF, Hickey WF, Trotter JL, Tilton RG. Aminoguanidine, an inhibitor of inducible nitric oxide synthase ameliorates experimental autoimmune encephalomyelitis in SJL mice. J Clin Invest 1994; 93: 2684-2690.
    • (1994) J Clin Invest , vol.93 , pp. 2684-2690
    • Cross, A.H.1    Misko, T.P.2    Lin, R.F.3    Hickey, W.F.4    Trotter, J.L.5    Tilton, R.G.6
  • 38
  • 39
    • 0028941990 scopus 로고
    • Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autommune encephalomyelitis
    • Zielasek JJ, Jung S, Gold R, Liew FY, Toyka KV, Hartung H-P. Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autommune encephalomyelitis. J Neuroimmunol 1995; 58: 81-88.
    • (1995) J Neuroimmunol , vol.58 , pp. 81-88
    • Zielasek, J.J.1    Jung, S.2    Gold, R.3    Liew, F.Y.4    Toyka, K.V.5    Hartung, H.-P.6
  • 40
    • 0029827401 scopus 로고    scopus 로고
    • A pharmacological study on the role of nitric oxide in the pathogenesis of experimental allergic encephalomyelitis
    • Scott GS, Williams KI, Bolton C. A pharmacological study on the role of nitric oxide in the pathogenesis of experimental allergic encephalomyelitis. Inflamm Res 1996; 45: 524-529.
    • (1996) Inflamm Res , vol.45 , pp. 524-529
    • Scott, G.S.1    Williams, K.I.2    Bolton, C.3
  • 41
    • 0030947511 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) receptor-mediated events contribute to neurovascular breakdown during experimental allergic encephalomyelitis (EAE)
    • Paul C, Scott GS, Harbour M, Seiler N, Bolton C. N-methyl-D-aspartate (NMDA) receptor-mediated events contribute to neurovascular breakdown during experimental allergic encephalomyelitis (EAE). Biochem Soc Trans 1997; 25: 1665.
    • (1997) Biochem Soc Trans , vol.25 , pp. 1665
    • Paul, C.1    Scott, G.S.2    Harbour, M.3    Seiler, N.4    Bolton, C.5
  • 42
    • 0021061744 scopus 로고
    • Blood-brain barrier breakdown in brain edema following cold injury is mediated by microvascular polyamines
    • Koenig H, Goldstone AD, Lu CY. Blood-brain barrier breakdown in brain edema following cold injury is mediated by microvascular polyamines. Biochem Biophys Res Commun 1983; 116: 1039-1048.
    • (1983) Biochem Biophys Res Commun , vol.116 , pp. 1039-1048
    • Koenig, H.1    Goldstone, A.D.2    Lu, C.Y.3
  • 43
    • 0024508297 scopus 로고
    • Blood brain barrier breakdown in cold-infused brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: Both are coordinately inhibited by verapamil, dexamethasone, and aspirin
    • Koenig H, Goldstone AD, Lu CY. Blood brain barrier breakdown in cold-infused brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: both are coordinately inhibited by verapamil, dexamethasone, and aspirin. J Neurochem 1989; 52: 101-109.
    • (1989) J Neurochem , vol.52 , pp. 101-109
    • Koenig, H.1    Goldstone, A.D.2    Lu, C.Y.3
  • 44
    • 0024462440 scopus 로고
    • NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices
    • Garthwaite J, Garthwaite G, Palmer RMJ, Moncada S. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur J Pharmacol 1989; 172: 413-416.
    • (1989) Eur J Pharmacol , vol.172 , pp. 413-416
    • Garthwaite, J.1    Garthwaite, G.2    Palmer, R.M.J.3    Moncada, S.4
  • 45
    • 3042735852 scopus 로고
    • Brain polyamines are controlled by N-methyl-D-aspartate receptors during ischemia and recirculation
    • Koenig H, Goldstone AD, Lu CY, Troat JJ. Brain polyamines are controlled by N-methyl-D-aspartate receptors during ischemia and recirculation. Stroke 1990; 21: 98-111.
    • (1990) Stroke , vol.21 , pp. 98-111
    • Koenig, H.1    Goldstone, A.D.2    Lu, C.Y.3    Troat, J.J.4
  • 46
    • 0026666213 scopus 로고
    • Capillary NMDA receptors regulate blood-brain barrier function and breakdown
    • Koenig H, Trout JJ, Goldstone AD, Lu CY. Capillary NMDA receptors regulate blood-brain barrier function and breakdown. Brain Res 1992; 588: 297-303.
    • (1992) Brain Res , vol.588 , pp. 297-303
    • Koenig, H.1    Trout, J.J.2    Goldstone, A.D.3    Lu, C.Y.4
  • 47
    • 0030868197 scopus 로고    scopus 로고
    • MK-801 limits neurovascular dysfunction in experimental allergic encephalomyelitis
    • Bolton C, Paul C. MK-801 limits neurovascular dysfunction in experimental allergic encephalomyelitis. J Pharm Exp Therap 1997; 282: 397-402.
    • (1997) J Pharm Exp Therap , vol.282 , pp. 397-402
    • Bolton, C.1    Paul, C.2
  • 48
    • 6844230293 scopus 로고    scopus 로고
    • Pharmacological evidence of a role for N-methyl-D-aspartate (NMDA) receptor generated polyamines in neurovascular breakdown during experimental allergic encephalomyelitis (EAE)
    • in press
    • Paul C, Seiler NB, Bolton C. Pharmacological evidence of a role for N-methyl-D-aspartate (NMDA) receptor generated polyamines in neurovascular breakdown during experimental allergic encephalomyelitis (EAE). J Neuroimmunol (in press).
    • J Neuroimmunol
    • Paul, C.1    Seiler, N.B.2    Bolton, C.3
  • 49
    • 0030008498 scopus 로고    scopus 로고
    • Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis
    • Wallstrom H, Diener P, Ljungdahl A, Khademi M, Nilsson C-G, Olsson T. Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis. J Neurol sci 1996; 137: 89-96.
    • (1996) J Neurol Sci , vol.137 , pp. 89-96
    • Wallstrom, H.1    Diener, P.2    Ljungdahl, A.3    Khademi, M.4    Nilsson, C.-G.5    Olsson, T.6
  • 50
    • 0024826077 scopus 로고
    • Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental allergic encephalomyelitis
    • Claudio L, Kressy Y, Norton WT, Brosnan CF. Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental allergic encephalomyelitis. Am J Pathol 1989; 135: 1157-1168.
    • (1989) Am J Pathol , vol.135 , pp. 1157-1168
    • Claudio, L.1    Kressy, Y.2    Norton, W.T.3    Brosnan, C.F.4
  • 51
    • 0026752465 scopus 로고
    • Metabolically dependent blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis
    • Hawkins CP, Munro PMG, London DN, McDonald WI. Metabolically dependent blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis. Acta Neuropathol 1992; 83: 630-635.
    • (1992) Acta Neuropathol , vol.83 , pp. 630-635
    • Hawkins, C.P.1    Munro, P.M.G.2    London, D.N.3    McDonald, W.I.4
  • 52
    • 0017487289 scopus 로고
    • The large apparent work capacity of the blood-brain barrier: A study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat
    • Oldendorf WH, Cornford ME, Brown WJ. The large apparent work capacity of the blood-brain barrier: a study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat. Ann Neurol 1977; 1: 409-417.
    • (1977) Ann Neurol , vol.1 , pp. 409-417
    • Oldendorf, W.H.1    Cornford, M.E.2    Brown, W.J.3
  • 53
    • 0024533652 scopus 로고
    • Ultrastructural and ultracytochemical studies on the blood-brain barrier in chronic relapsing experimental allergic encephalomyelitis
    • Kato S, Nakamura H. Ultrastructural and ultracytochemical studies on the blood-brain barrier in chronic relapsing experimental allergic encephalomyelitis. Acta Neuropathol 1989; 77: 455-464.
    • (1989) Acta Neuropathol , vol.77 , pp. 455-464
    • Kato, S.1    Nakamura, H.2
  • 54
    • 0023114078 scopus 로고
    • Demyelination and neurological signs in experimental allergic encephalomyelitis
    • Pender MP. Demyelination and neurological signs in experimental allergic encephalomyelitis. J Neurol 1987; 15: 11-24.
    • (1987) J Neurol , vol.15 , pp. 11-24
    • Pender, M.P.1
  • 55
    • 0023147156 scopus 로고
    • Secretory products of macrophages
    • Nathan CF. Secretory products of macrophages. J Clin Invest 1987; 79: 319-326.
    • (1987) J Clin Invest , vol.79 , pp. 319-326
    • Nathan, C.F.1
  • 56
    • 0026746211 scopus 로고
    • Inflammatory mediators in demyelinating disorders of the CNS and PNS
    • Hartung H-P, Jung S, Stoll G, et al. Inflammatory mediators in demyelinating disorders of the CNS and PNS. J Neuroimmunol 1992; 40: 197-210.
    • (1992) J Neuroimmunol , vol.40 , pp. 197-210
    • Hartung, H.-P.1    Jung, S.2    Stoll, G.3
  • 57
    • 0000420103 scopus 로고
    • A study of abnormal blood-brain barrier permeability in experimental allergic encephalomyelitis
    • Barlow CF. A study of abnormal blood-brain barrier permeability in experimental allergic encephalomyelitis. J Neuropathol Exp Neurol 1956; 15: 196-208.
    • (1956) J Neuropathol Exp Neurol , vol.15 , pp. 196-208
    • Barlow, C.F.1
  • 58
    • 0006509051 scopus 로고
    • Permeability of cerebral blood vessels in experimental allergic encephalomyelitis studied by radioactive iodinated bovine albumin
    • Vulpe NM, Hawkins A, Rozdilsky B. Permeability of cerebral blood vessels in experimental allergic encephalomyelitis studied by radioactive iodinated bovine albumin. Neurology 1960; 10: 171-177.
    • (1960) Neurology , vol.10 , pp. 171-177
    • Vulpe, N.M.1    Hawkins, A.2    Rozdilsky, B.3
  • 60
    • 0014249830 scopus 로고
    • Immunohistochemical study of allergic encephalomyelitis
    • Oldstone MBA, Dixon FJ. Immunohistochemical study of allergic encephalomyelitis. Am J Path 1968; 52: 251-263.
    • (1968) Am J Path , vol.52 , pp. 251-263
    • Oldstone, M.B.A.1    Dixon, F.J.2
  • 61
    • 0015333994 scopus 로고
    • Cerebral vessel permeability and cellular infiltration in experimental allergic encephalomyelitis
    • Leibowitz S, Kennedy L. Cerebral vessel permeability and cellular infiltration in experimental allergic encephalomyelitis. Immunology 1972; 22: 859-869.
    • (1972) Immunology , vol.22 , pp. 859-869
    • Leibowitz, S.1    Kennedy, L.2
  • 62
    • 0002393266 scopus 로고
    • Electron microscopic studies of the vascular permeability and the mechanism of demyelination in experimental allergic encephalomyelitis
    • Lampert P, Carpenter S. Electron microscopic studies of the vascular permeability and the mechanism of demyelination in experimental allergic encephalomyelitis. J Neuropath Exp Neurol 1965; 24: 11-24.
    • (1965) J Neuropath Exp Neurol , vol.24 , pp. 11-24
    • Lampert, P.1    Carpenter, S.2
  • 63
    • 0014816259 scopus 로고
    • Fine structural alterations of the blood-brain barrier in experimental allergic encephalomyelitis
    • Hirano A, Dembitzer HM, Becker NH, Levine S, Zimmerman HM. Fine structural alterations of the blood-brain barrier in experimental allergic encephalomyelitis. J Neuropath Exp Neurol 1970; 29: 432-440.
    • (1970) J Neuropath Exp Neurol , vol.29 , pp. 432-440
    • Hirano, A.1    Dembitzer, H.M.2    Becker, N.H.3    Levine, S.4    Zimmerman, H.M.5
  • 64
    • 0025218689 scopus 로고
    • Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis studied by gadolinium DTPA and protein markers
    • Hawkins CP, Munro PMG, Mackenzie F, et al. Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis studied by gadolinium DTPA and protein markers. Brain 1990; 113: 365-378.
    • (1990) Brain , vol.113 , pp. 365-378
    • Hawkins, C.P.1    Munro, P.M.G.2    Mackenzie, F.3
  • 65
    • 0022345478 scopus 로고
    • Early detection of experimental allergic encephalomyelitis by magnetic resonance imaging
    • Stewart WA, Alvord EC, Hruby S, Hall LD, Paty DW. Early detection of experimental allergic encephalomyelitis by magnetic resonance imaging. Lancet 1985; ii: 898.
    • (1985) Lancet , vol.2 , pp. 898
    • Stewart, W.A.1    Alvord, E.C.2    Hruby, S.3    Hall, L.D.4    Paty, D.W.5
  • 66
    • 0023719084 scopus 로고
    • Gd-enhanced MR imaging of acute and chronic experimental demyelinating lesions
    • Kuharik MA, Edwards MK, Farlow MR, et al. Gd-enhanced MR imaging of acute and chronic experimental demyelinating lesions. Am J Neuroradiol 1988; 9: 643-648.
    • (1988) Am J Neuroradiol , vol.9 , pp. 643-648
    • Kuharik, M.A.1    Edwards, M.K.2    Farlow, M.R.3
  • 68
    • 0017855244 scopus 로고
    • The capillaries in acute and subacute multiple sclerosis - A morphometric analysis
    • Brown WJ. The capillaries in acute and subacute multiple sclerosis - a morphometric analysis. Neurology 1978; 28: 84-92.
    • (1978) Neurology , vol.28 , pp. 84-92
    • Brown, W.J.1
  • 69
    • 0023751637 scopus 로고
    • Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis
    • Miller DH, Rudge P, Johnson G, et al. Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis. Brain 1988; 111: 927-939.
    • (1988) Brain , vol.111 , pp. 927-939
    • Miller, D.H.1    Rudge, P.2    Johnson, G.3
  • 71
    • 13344294370 scopus 로고    scopus 로고
    • In vivo MRI and its histological correlaters in acute adoptive transfer experimental allergic encephalomyelitis
    • Morrisey SP, Stodal H, Zettl U, et al. In vivo MRI and its histological correlaters in acute adoptive transfer experimental allergic encephalomyelitis. Brain 1996; 119: 239-248.
    • (1996) Brain , vol.119 , pp. 239-248
    • Morrisey, S.P.1    Stodal, H.2    Zettl, U.3
  • 72
    • 0027502465 scopus 로고
    • Blood-brain barrier breakdown in MBP-specific T cell induced experimental allergic encephalomyelitis
    • Namer IJ, Steibel J, Poulet P, et al. Blood-brain barrier breakdown in MBP-specific T cell induced experimental allergic encephalomyelitis. Brain 1993; 116: 147-149.
    • (1993) Brain , vol.116 , pp. 147-149
    • Namer, I.J.1    Steibel, J.2    Poulet, P.3
  • 73
    • 0014109002 scopus 로고
    • Fine structural localisation of a blood-brain barrier to exogenous peroxidase
    • Reese TS, Karnovsky MSJ. Fine structural localisation of a blood-brain barrier to exogenous peroxidase. J Cell Biol 1967; 34: 207-217.
    • (1967) J Cell Biol , vol.34 , pp. 207-217
    • Reese, T.S.1    Karnovsky, M.S.J.2
  • 74
    • 0014481056 scopus 로고
    • Junctions between intimately opposed cell membranes in the vertebrate brain
    • Brightman MW, Reese TS. Junctions between intimately opposed cell membranes in the vertebrate brain. J Cell Biol 1969; 40: 648-677.
    • (1969) J Cell Biol , vol.40 , pp. 648-677
    • Brightman, M.W.1    Reese, T.S.2
  • 75
    • 0024826077 scopus 로고
    • Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental autoimmune encephalomyelitis
    • Claudio L, Kress Y, Norton WT, Brosnan CF. Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental autoimmune encephalomyelitis. Am J Pathol 1989; 135: 1157-1168.
    • (1989) Am J Pathol , vol.135 , pp. 1157-1168
    • Claudio, L.1    Kress, Y.2    Norton, W.T.3    Brosnan, C.F.4
  • 76
    • 0024361040 scopus 로고
    • Sites of egress of inflammatory cells and horseradish peroxidase transport across the blood-brain barrier in a murine model of chronic relapsing experimental allergic encephalomyelitis
    • Lossinsky AS, Badmajew V, Robson JA, Moretz RC, Wisniewski HM. Sites of egress of inflammatory cells and horseradish peroxidase transport across the blood-brain barrier in a murine model of chronic relapsing experimental allergic encephalomyelitis. Acta Neuropathol 1989; 78: 359-371.
    • (1989) Acta Neuropathol , vol.78 , pp. 359-371
    • Lossinsky, A.S.1    Badmajew, V.2    Robson, J.A.3    Moretz, R.C.4    Wisniewski, H.M.5
  • 77
    • 0007212336 scopus 로고
    • The application of quantitative immunocytochemistry for the evaluation of blood-brain barrier (BBB) to endogenous albumin
    • Greenwood J, Begley DJ, Segal MB, eds. New York: Plenum Press
    • Vorbrodt AW. The application of quantitative immunocytochemistry for the evaluation of blood-brain barrier (BBB) to endogenous albumin. In: Greenwood J, Begley DJ, Segal MB, eds. New Concepts of a Blood-Brain Barrier. New York: Plenum Press, 1995; 39-16.
    • (1995) New Concepts of a Blood-Brain Barrier , pp. 39-116
    • Vorbrodt, A.W.1
  • 78
    • 0023881980 scopus 로고
    • Slow penetration of thyrotropin releasing hormone across the blood-brain barrier of in situ perfused guinea-pig brain
    • Zlokovic BV, Lipovac MN, Begley DJ, Dawson H, Rakic L. Slow penetration of thyrotropin releasing hormone across the blood-brain barrier of in situ perfused guinea-pig brain. J Neurochem 1988; 51: 252-257.
    • (1988) J Neurochem , vol.51 , pp. 252-257
    • Zlokovic, B.V.1    Lipovac, M.N.2    Begley, D.J.3    Dawson, H.4    Rakic, L.5
  • 79
    • 0016287151 scopus 로고
    • Blood-brain barrier and DNA changes during the evolution of experimental allergic encephalomyelitis
    • Oldendorf WH, Towner HF. Blood-brain barrier and DNA changes during the evolution of experimental allergic encephalomyelitis. J Neuropathol Exp Neurol 1974; 33: 616-631.
    • (1974) J Neuropathol Exp Neurol , vol.33 , pp. 616-631
    • Oldendorf, W.H.1    Towner, H.F.2
  • 80
    • 0019468697 scopus 로고
    • Changes in the effectiveness of the blood-brain barrier and blood-spinal cord barrier in experimental allergic encephalomyelitis
    • Daniel PM, Lam DKC, Pratt OB. Changes in the effectiveness of the blood-brain barrier and blood-spinal cord barrier in experimental allergic encephalomyelitis. J Neurol Sci 1981; 52: 211-219.
    • (1981) J Neurol Sci , vol.52 , pp. 211-219
    • Daniel, P.M.1    Lam, D.K.C.2    Pratt, O.B.3
  • 81
    • 0029099691 scopus 로고
    • Inhibition of blood-brain barrier disruption in experimental allergic encephalomyelitis by short-term therapy with dexamethasone and cyclosporin A
    • Paul C, Bolton C. Inhibition of blood-brain barrier disruption in experimental allergic encephalomyelitis by short-term therapy with dexamethasone and cyclosporin A. Int J Immunopharm 1995; 17: 497-503.
    • (1995) Int J Immunopharm , vol.17 , pp. 497-503
    • Paul, C.1    Bolton, C.2
  • 83
    • 4243419373 scopus 로고
    • Autocoids as mediators of vasogenic brain oedema
    • Greenwood J, Begley DJ, Segal MB, eds. New York: Plenum Press
    • Wahl M, Schilling L, Unterberg A, Baethmann A. Autocoids as mediators of vasogenic brain oedema. In: Greenwood J, Begley DJ, Segal MB, eds. New Concepts of a Blood-Brain Barrier. New York: Plenum Press, 1995; 147-148.
    • (1995) New Concepts of a Blood-Brain Barrier , pp. 147-148
    • Wahl, M.1    Schilling, L.2    Unterberg, A.3    Baethmann, A.4
  • 84
    • 0021953358 scopus 로고
    • Blood-brain barrier: Endogenous modulation by adrenal-cortical function
    • Long JB, Holladay JW. Blood-brain barrier: endogenous modulation by adrenal-cortical function. Science 1985; 227: 1580-1583.
    • (1985) Science , vol.227 , pp. 1580-1583
    • Long, J.B.1    Holladay, J.W.2
  • 85
    • 0022617501 scopus 로고
    • Effect of dexamethasone on the blood-brain barrier in the normal mouse
    • Hedley-Whyte ET, Hsu DW. Effect of dexamethasone on the blood-brain barrier in the normal mouse. Ann Neurol 1986; 19: 373-377.
    • (1986) Ann Neurol , vol.19 , pp. 373-377
    • Hedley-Whyte, E.T.1    Hsu, D.W.2
  • 86
    • 0023790666 scopus 로고
    • Effects of dexamethasone on transport of α-aminobutyric acid across the blood-brain barrier
    • Zlylan YZ, Le Fauconnier UJM, Bernard G, Bourre JM. Effects of dexamethasone on transport of α-aminobutyric acid across the blood-brain barrier. J Neurochem 1988; 51: 1338-1342.
    • (1988) J Neurochem , vol.51 , pp. 1338-1342
    • Zlylan, Y.Z.1    Le Fauconnier, U.J.M.2    Bernard, G.3    Bourre, J.M.4
  • 88
    • 0024534407 scopus 로고
    • Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids
    • MacPhee IAM, Antoni FA, Mason DW. Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids. J Exp Med 1989; 169: 431-445.
    • (1989) J Exp Med , vol.169 , pp. 431-445
    • MacPhee, I.A.M.1    Antoni, F.A.2    Mason, D.W.3
  • 89
    • 0024311303 scopus 로고
    • The effects of the anti-glucocorticoid RU38486 on steroid-mediated supression of experimental allergic encephalomyelitis in the Lewis rat
    • Bolton C, Flower RJ. The effects of the anti-glucocorticoid RU38486 on steroid-mediated supression of experimental allergic encephalomyelitis in the Lewis rat. Life Sci 1989; 45: 97-104.
    • (1989) Life Sci , vol.45 , pp. 97-104
    • Bolton, C.1    Flower, R.J.2
  • 90
    • 0020619375 scopus 로고
    • Glucocorticoids modulate the response of ornithine decarboxylase to unilateral removal of the dorsal hippocampus
    • De Kloet ER, Cousin MA, Veldhuis HD, Voorhuis TD, Lando D. Glucocorticoids modulate the response of ornithine decarboxylase to unilateral removal of the dorsal hippocampus. Brain Res 1983; 275: 91-98.
    • (1983) Brain Res , vol.275 , pp. 91-98
    • De Kloet, E.R.1    Cousin, M.A.2    Veldhuis, H.D.3    Voorhuis, T.D.4    Lando, D.5
  • 91
    • 0026578545 scopus 로고
    • Demonstration of steroid hormone receptors and steroid action in primary cultures of rat glial cells
    • Jung-Testas I, Renoir M, Bugnard H, Greene GL, Baulieu E. Demonstration of steroid hormone receptors and steroid action in primary cultures of rat glial cells. J Steroid Biochem Mol Biol 1992; 41: 621-631.
    • (1992) J Steroid Biochem Mol Biol , vol.41 , pp. 621-631
    • Jung-Testas, I.1    Renoir, M.2    Bugnard, H.3    Greene, G.L.4    Baulieu, E.5
  • 92
    • 0022393232 scopus 로고
    • Prazosin an alpha-1 adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat
    • Brosnan CF, Goldmuntz EA, Cammer W, Factor SM, Bloom BR, Norton WT. Prazosin an alpha-1 adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat. Proc Natl Acad Sci USA 1985; 82: 5915-5921.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 5915-5921
    • Brosnan, C.F.1    Goldmuntz, E.A.2    Cammer, W.3    Factor, S.M.4    Bloom, B.R.5    Norton, W.T.6
  • 93
    • 0022996497 scopus 로고
    • Prazosin treatment suppresses increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat
    • Goldmuntz EA, Brosnan CF, Norton WT. Prazosin treatment suppresses increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat. J Immunol 1986; 137: 3444-3450.
    • (1986) J Immunol , vol.137 , pp. 3444-3450
    • Goldmuntz, E.A.1    Brosnan, C.F.2    Norton, W.T.3
  • 94
    • 0021192035 scopus 로고
    • Modulation by cyclosporin-A of mononuclear cell distribution during experimental allergic encephalomyelitis
    • Rumjanek VM, Smith LA, Morley J. Modulation by cyclosporin-A of mononuclear cell distribution during experimental allergic encephalomyelitis. Int J Immunopharmacol 1984; 6: 99-104.
    • (1984) Int J Immunopharmacol , vol.6 , pp. 99-104
    • Rumjanek, V.M.1    Smith, L.A.2    Morley, J.3
  • 95
    • 0022454822 scopus 로고
    • Cyclosporin-A treatment of experimental allergic encephalomyelitis: Changes in immunological regulation and blood-CSF barrier function
    • Reiber H, Suckling AJ. Cyclosporin-A treatment of experimental allergic encephalomyelitis: changes in immunological regulation and blood-CSF barrier function. J Neuroimmunol 1986; 12: 121-130.
    • (1986) J Neuroimmunol , vol.12 , pp. 121-130
    • Reiber, H.1    Suckling, A.J.2
  • 97
    • 0027471305 scopus 로고
    • Blockade of endothelium-dependent responses in conscious rats by cyclosporin A: Effect of L-arginine
    • Gallego MJ, Farre AL, Riesco A, et al. Blockade of endothelium-dependent responses in conscious rats by cyclosporin A: effect of L-arginine. Am J Physiol Heart Circ Physiol 1993; 264: H708-H714.
    • (1993) Am J Physiol Heart Circ Physiol , vol.264
    • Gallego, M.J.1    Farre, A.L.2    Riesco, A.3
  • 98
    • 0027184839 scopus 로고
    • Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins
    • Ryffel B. Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins. Biochem Pharmacol 1993; 46: 1-12.
    • (1993) Biochem Pharmacol , vol.46 , pp. 1-12
    • Ryffel, B.1
  • 99
    • 0025087968 scopus 로고
    • Permeability of the blood-brain barrier to the immunosuppressive cyclic peptide cyclosporin A
    • Begley DJ, Squires LK, Zlokovic BV, et al. Permeability of the blood-brain barrier to the immunosuppressive cyclic peptide cyclosporin A. J Neurochem 1990; 55: 1222-1230.
    • (1990) J Neurochem , vol.55 , pp. 1222-1230
    • Begley, D.J.1    Squires, L.K.2    Zlokovic, B.V.3
  • 100
    • 0028998552 scopus 로고
    • Effect of the p-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: An in vivo microdialysis study in freely moving rats
    • Wang Q, Yang H, Miller DW, Elmquist WF. Effect of the p-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: an in vivo microdialysis study in freely moving rats. Biochem Biophys Res Comm 1995; 211: 719-726.
    • (1995) Biochem Biophys Res Comm , vol.211 , pp. 719-726
    • Wang, Q.1    Yang, H.2    Miller, D.W.3    Elmquist, W.F.4
  • 101
    • 0027998226 scopus 로고
    • In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier
    • Sakata A, Tama I, Kawazuk K, et al. In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier. Biochem Pharmacol 1994; 48: 1989-1992.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1989-1992
    • Sakata, A.1    Tama, I.2    Kawazuk, K.3
  • 102
    • 0026514505 scopus 로고
    • Vincristine in therapeutic doses appears to increase blood-brain permeability to colchicine in the anaesthetised guinea-pig
    • Begley DJ, Evans JE. Vincristine in therapeutic doses appears to increase blood-brain permeability to colchicine in the anaesthetised guinea-pig. J Physiol 1992; 446: 449P.
    • (1992) J Physiol , vol.446
    • Begley, D.J.1    Evans, J.E.2
  • 103
    • 85088673820 scopus 로고    scopus 로고
    • Role of p-glycoprotein in the blood-brain transport of colchicine and vinblastine
    • Drion M, Lemarie M, Lefauconnier JM, Scherrmann JM. Role of p-glycoprotein in the blood-brain transport of colchicine and vinblastine. J Neurol 1996; 67: 1668-1693.
    • (1996) J Neurol , vol.67 , pp. 1668-1693
    • Drion, M.1    Lemarie, M.2    Lefauconnier, J.M.3    Scherrmann, J.M.4


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