Effects of the dual metallopeptidase inhibitor, MDL 100,240, on regional haemodynamic responses to vasoactive peptides in conscious rats

British Journal of Pharmacology

Volumn 122, Issue 8, 1997, Pages 1687-1693

  Gardiner, S M ^a   Kemp, P A ^a   Brunner Ferber, F ^b   Bennett, T ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b Clinical Pharmacology   (France)

Author keywords

Angiotensin I; Angiotensin II; ANP; Big endothelin 1; Bradykinin; Dual metallopeptidase inhibitor; Endothelin 1

Indexed keywords

7 (2 ACETYLTHIO 3 PHENYLPROPIONAMIDO) 1,2,3,4,6,7,8,12B OCTAHYDRO 6 OXOPYRIDO[2,1 A][2]BENZAZEPINE 4 CARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN I; ATRIAL NATRIURETIC FACTOR; BIG ENDOTHELIN 1; BRADYKININ; ENDOTHELIN 1; ENKEPHALINASE INHIBITOR; MEMBRANE METALLOENDOPEPTIDASE; METALLOPROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VASOACTIVE AGENT;

ANIMAL EXPERIMENT; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; HEMODYNAMICS; HYPERTENSION; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY BLOOD FLOW; MALE; MEAN ARTERIAL PRESSURE; MESENTERY BLOOD FLOW; MOUSE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; TACHYCARDIA; VASODILATATION;

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ATRIAL NATRIURETIC FACTOR; BENZAZEPINES; BRADYKININ; ENDOTHELIN-1; HEMODYNAMIC PROCESSES; MALE; NEPRILYSIN; PROTEASE INHIBITORS; PYRIDINES; RATS;

EID: 0031466757     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701550     Document Type: Article

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