Familial aspects of the hypertension syndrome

European Journal of Cardiovascular Prevention & Rehabilitation

Volumn 4, Issue 4, 1997, Pages 243-249

  Neutel, Joel M ^a   Smith, David H G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

genetics of hypertension; hypertension; hypertension prone; insulin resistance; syndrome X

Indexed keywords

ARTERY COMPLIANCE; GENETICS; GLUCOSE METABOLISM; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; HYPERTENSION; INSULIN METABOLISM; INSULIN RESISTANCE; KIDNEY FUNCTION; OBESITY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SYNDROME X;

BLOOD PRESSURE; CORONARY DISEASE; HUMANS; HYPERTENSION; RISK FACTORS; SYNDROME;

EID: 0031466545     PISSN: 17418267     EISSN: 17418275     Source Type: Journal    
DOI: 10.1177/174182679700400402     Document Type: Article

References (62)

1. Samuelsson OG, Wilhelmsen LW, Svardsudd KF, Pennert KM, Wedel H, Berglund GL: Mortality and morbidity in relation to systolic blood pressure in two populations with different management of hypertension: The study of men born in 1913 and the multifactorial primary prevention trial J Hypertens 1987, 5: 57–66.
2. Grimm RH Jr., Flack JM, Byington R, Bond G, Brugger S: A comparison of antihypertensive drug effects on the progression of extracranial carotid atherosclerosis. The Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS) Drugs 1990, 40: 38–43.
3. MacMahon SW, Cutler JA, Furberg CD, Payne GH: The effects of drug treatment for hypertension on morbidity and mortality from cardiovascular disease. A review of randomized controlled trials Prog Cardiovasc Dis 1986, 29 (suppl 1):99–118.
4. Krotkiewski M, Mandroukas K, Sjostrom I, Sullivan L, Wetterqvist H, Bjorntorp P: Effects of long-term physical training on body fat, metabolism, and blood pressure in obesity Metabolism 1979. 28: 650–658.
5. The Pooling Project Research Group: Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence of major coronary events: Final report of the Pooling Project J Chron Dis 1978, 31: 201–206.
6. Scannapieco G, Pauletta P, Pagnan A: Lipoprotein binding to cultured aortic smooth muscle cells from normotensive and hypertensive rats J Hypertens 1988, 6 (suppl 4):S269–S271.
7. Neutel JM, Smith DHG, Graettinger WF, Winer RL, Weber MA: Heredity and hypertension: Impact on metabolic characteristics Am Heart J 1992, 124: 435–440. * This article provides compelling evidence that hypertension is a syndrome of cardiovascular abnormalities which include lipids, insulin and left ventricular hypertrophy. Many of the associated cardiovascular risk factors may be present prior to the abnormalities of blood pressure.
8. Sammelsson O, Wilmhelmsen L, Anderson OK, Pinnert K, Berglund G: Cardiovascular morbidity in relation to change in blood pressure and serum cholesterol levels in treated hypertension JAMA 1987, 285: 1768–1776.
9. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP: Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study N Engl J Med 1990, 322: 1561–1566.
10. Cassale PN, Milner A, Devereux RB: Value of echocardiographic left ventricular mass in predicting cardiovascular morbidity events in hypertensive men Circulation 1985, 72: 130–135.
11. Devereux RB, Reichek N: Electrocardiographic determination of left ventricular mass in man: Anatomic validation of the method Circulation 1977, 66: 613–618.
12. Savage DD, Drayer JIM, Henry WL: Echocardiographic assessment of cardiac anatomy and function in hypertensive subjects Circulation 1979, 59: 623–632.
13. Drayer JIM, Weber MA, Laragh JH: Echocardiography in the evaluation of patients with mild or borderline hypertension In Treatment Strategies in Hypertension. Edited by Weber MA. Miami: Symposia Specialists; 1981: 21–32.
14. Celentano A, Galderisis M, Garafalo M: Blood pressure and cardiac morphology in young children of hypertensive subjects J Hypertens 1988, 6 (suppl 4):S107–S109.
15. Giligan JP, Spector S: Synthesis of collagen in cardiac and vascular hypertension Hypertension 1994, 6 (suppl 3):1144–1149. ∗ This article discusses the importance of collagen lay down in cardiovascular smooth muscle which contributes to decreased arterial compliance.
16. Safar ME, Laurent S, Pannier BM, London GM: Structural and functional modification of peripheral large arteries in hypertensive patients J Clin Hypertens 1987, 3: 360–367.
17. Finkelstein SM, Collins VR, Cohn JN: Arterial vascular compliance response to vasodilators by Fourier and pulse contour analysis Hypertension 1988, 12: 380–387. ∗ Discusses a new technique for measuring proximal and reflective arterial compliance.
18. O'Rourke M: Arterial stiffness, systolic blood pressure, and logical treatment of arterial hypertension Hypertension 1990, 15: 339–347.
19. Safar ME, London GM: Arterial and venous compliance in sustained essential hypertension Hypertension 1987, 10: 133–139.
20. McVeigh GE, Burns DE, Carlyle PF, Finkelstein SM, Cohn JN: Vascular compliance in essential hypertension Circulation 1989, 80: 11594–11599.
21. Weber MA, Smith DHG, Neutel JM, Graettinger WF: Arterial properties of early hypertension J Hum Hypertens 1991, 5: 417–423. * This article discusses the importance of reduced arterial compliance in hypertensive patients. It also demonstrates the time course of changes of compliance which becomes abnormal early on in the course of the disease.
22. Shu WCV, Gardin JM, Knoll ML, Weber MA: Assessment of left ventricular systolic and diastolic function with Doppler echocardiography in patients receiving intravenous medroxalol Am Heart J 1990, 120: 87–95.
23. Graettinger WF, Neutel JM, Smith DHG, Weber MA: Left ventricular diastolic filling alterations in normotensive young adults with a family history of systemic hypertension Am J Cardiol 1991, 68: 51–56.
24. Modan M, Halkin H, Almog S: Hyperinsulinemia: A link between hypertension, obesity and glucose intolerance J Clin Invest 1985, 75: 809–817.
25. Swislocki ALM, Hoffman BB, Reaven GM: Insulin resistance, glucose intolerance and hyperinsulinemia in patients with hypertension Am J Hypertens 1989, 2: 419–423.
26. Hunt SC, Stephenson SH, Hopkins PN, Hasstedt SJ, Williams RR: A prospective study of sodium-lithium counter-transport and hypertension in Utah Hypertension 1991, 17: 1–7.
27. Laurenzl M, Trevisan M: Sodium-lithium countertransport and blood pressure: The Gubbio Population Study Hypertension 1989, 13: 408–415.
28. Trevisan M, Laurenzi M: Correlates of sodium-lithium countertransport. Findings from the Gubbio Epidemiological Study. The Gubbio Collaborative Study Group Circulation 1991, 84: 2011–2019.
29. Williams RR, Hunt SC, Hassted SJ, Stephenson SH, Hopkins PN: Multigenic human hypertension: Evidence for subtypes and hope for haplotypes J Hypertens 1990, 8 (suppl):S39–S46.
30. Gupta AK, Clark RV, Kirchner KA: Effects of insulin on renal sodium excretion Hypertension 1992, 19 (suppl 1):8–82. ∗ Discusses the potential role of insulin in the pathophysiology of hypertension demonstrating that its action on the kidney may result in increased blood pressure.
31. Reaven GM, Hoffman BB: A role for insulin in the aetiology and course of hypertension Lancet 1987, ii: 435–437.
32. Tuck M, Corry D, Trujillo A: Salt-sensitive blood pressure and exaggerated vascular reactivity in the hypertension of diabetes mellitus Am J Med 1990, 88: 210–216.
33. Rocchini AP, Moorehead C, DeRemer S, Goodfriend TL, Ball DL: Hyperinsulinemia and the aldosterone and pressor responses to angiotensin II Hypertension 1991, 15: 861–866.
34. Meehan WP, Buchanan TA, Shargil NS: Chronic insulin administration elevates blood pressure in rats [abstract] Circulation 1990, 82: 11–86.
35. Hall JE, Coleman TG, Leland-Mizelle H: Does chronic hyperinsulinemia cause hypertension? Am J Hypertens 1989, 2: 171–173.
36. Hall JE, Coleman TG, Leland-Mizelle HL, Smith MJ Jr: Chronic hyperinsulinemia and blood pressure regulation Am J Physiol 1990, 258: F722–F731.
37. Hall JE, Brands MW, Kivlighn SD, Coleman TG: Chronic hyperinsulinemia and blood pressure. Interaction with catecholamines? Hypertension 1990, 15: 519–527.
38. Brands MW, Mizelle HL, Gallard* CA, Hilderbrandt DA, Hall JE: The hemodynamic response to chronic hyperinsulinemia in conscious dogs Am J Hypertens 1991, 4: 164–168.
39. Brands MW, Hildebrandt DA, Mizelle HL, Hall JE: Hypertension during chronic hyperinsulinemia in rats in not salt-sensitive Hypertension 1992, 19: 183–189.
40. Tsutsu N, Nunoi K, Kodama T, Nomiyama R, Iwase M, Fujischima M: Lack of association between blood pressure and insulin in patients with insulinoma J Hypertens 1990, 8: 479–482.
41. Sowers JR: Insulin resistance and hypertension Mol Cell Endocrinol 1990, 74: C87–C89.
42. Feraille E, Krempf M, Charbonnel B, Bouhour JB, Nicolas G: Arterial hypertension in patients with obesity. Role of hyperinsulinemia and insulin resistance Rev Med Interne 1990, 11: 293–296.
43. Caro JF: Clinical review 26: Insulin resistance in obese and non-obese men J Clin Endocrinol Metab 1991, 73: 691–695.
44. Falkner B, Hulman S, Tannenbaum J, Kushner H: Insulin resistance and blood pressure in young black men Hypertension 1990, 16: 706–711. ∗Shows that associated risk factors in hypertensive patients occur early in the course of the disease process.
45. Warram JH, Martin BC, Krolewski AS, Soeldner JS, Kahn R: Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents Ann Intern Med 1990, 113: 909–915.
46. Banskota NK, Taub R, Zellner K, Olsen P, King GL: Characterization of induction of protooncogene c-myc and cellular growth in human vascular smooth muscle cells by insulin and IGF-I diabetes Diabetes 1989. 38: 123–129.
47. Robertson WB, Strong JP: Atherosclerosis in persons with hypertension and diabetes mellitus Lab Invest 1968, 18: 538–551.
48. Stout RW: Insulin and atheroma. 20-yr perspective Diabetes Care 1990, 13: 631–654.
49. Stout RW: Overview of the association between insulin and atherosclerosis Metabolism 1985, 34 (suppl):7–12.
50. Uusitupa MI, Niskanen LK, Siitonen O, Voutilainen E, Pyorala K: 5 year incidence of atherosclerotic vascular disease in relation to general risk factors, insulin level and abnormalities in lipoprotein composition in non-insulin-dependent diabetic and non-diabetic subjects Circulation 1990, 82: 27–36.
51. Fontbone A, Tchobroutsky G, Eschwege E, Richards JL, Claude Jr., Roselin GE: Coronary heart disease mortality risk. Plasma insulin level is a more sensitive marker than hypertension or abnormal glucose tolerance in overweight males. The Paris Prospective Study Int J Obes 1987, 12: 557–565.
52. Fontbone A, Eschwege E: Diabetes, hyperglycemia, hyperinsulinemia and atherosclerosis: Epidemiological data Diabetes Metab 1987, 13: 350–353.
53. Pyorala K, Savolainen E, Kaukola S, Haapakoski J: Plasma insulin as coronary heart disease risk factor: Relationship to other risk factors and predictive value during 9 1/2 year follow-up of the Helsinki Policeman Study population Acta Med Scand 1985, 701 (suppl):38–52.
54. Assman G, Schulte H: The prospective Cardiovascular Munster (PROCAM) study: Prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to coronary heart disease Am Heart J 1988, 116: 1713–1724.
55. Kaplan NM: The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension Arch Intern Med 1989, 149: 1514–1520.
56. Despres JP, Moorjani S, Lupien PJ, Tremblay A, Nadaeu A, Bouchard C: Regional distribution of body fat, plasma, lipoproteins, and cardiovascular disease Arteriosclerosis 1990, 10: 497–511.
57. Raison J, Bonithon KC, Egloff M, Ducimetiere P, Guy-Grand B: Hormonal influences on the relationship between body fatness, body fat distribution, lipids, lipoproteins, glucose and blood pressure in French working women Arteriosclerosis 1990, 85: 185–192.
58. Ducimetiere P, Richard J, Cambien F: The pattern of subcutaneous fat distribution in middle-aged men and the risk of coronary heart disease: The Paris Prospective Study Int J Obes 1986, 10: 229–240.
59. Krieger DR, Landsberg L: Mechanisms in obesity related hypertension. Role of insulin and catecholamines Am J Hypertens 1988, 1: 84–90.
60. Bonora E, Moghetti P, Zenere M, Tosi F, Travia D, Muggeo M: B cell secretion and insulin sensitivity in hypertensive and normotensive obese subjects Int J Obes 1990, 14: 735–742.
61. Laakso M, Sarlund H, Mykkanen L: Essential hypertension and insulin resistance in non-insulin dependant diabetes Eur J Clin Invest 1989, 19: 518–526.
62. Grunfield B, Perelstein E, Simsolo R, Gimenez M, Romero JC: Renal function reserve and microalbuminuria in offspring of hypertensive parents Hypertension 1990, 15: 257–261.