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Volumn 25, Issue 12, 1997, Pages 1337-1346

Effects of probenecid on brain-cerebrospinal fluid-blood distribution kinetics of E-δ2-valproic acid in rabbits

Author keywords

[No Author keywords available]

Indexed keywords

PROBENECID; VALPROIC ACID;

EID: 0031466148     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (13)

References (37)
  • 3
    • 0029925182 scopus 로고    scopus 로고
    • Valproic acid hepatic fatalities. III. U.S. experience since 1986
    • A. E. Bryant III and F. E. Dreifuss: Valproic acid hepatic fatalities. III. U.S. experience since 1986. Neurology 46, 465-469 (1996).
    • (1996) Neurology , vol.46 , pp. 465-469
    • Bryant III, A.E.1    Dreifuss, F.E.2
  • 4
    • 0026001902 scopus 로고
    • Valproic acid-induced neural tube defects in mouse and human: Aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms
    • H. Nau, R.-S. Hauck, and K. Ehlers: Valproic acid-induced neural tube defects in mouse and human: aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms. Pharmacol. Toxicol. 69, 310-321 (1991).
    • (1991) Pharmacol. Toxicol. , vol.69 , pp. 310-321
    • Nau, H.1    Hauck, R.-S.2    Ehlers, K.3
  • 6
    • 0021638232 scopus 로고
    • Valproic acid and metabolites: Pharmacological and toxicological studies
    • H. Nau and W. Loscher: Valproic acid and metabolites: pharmacological and toxicological studies. Epilepsia 25, (Suppl. 1) S14-S22 (1984).
    • (1984) Epilepsia , vol.25 , Issue.1 SUPPL.
    • Nau, H.1    Loscher, W.2
  • 7
    • 0026746731 scopus 로고
    • Effects of valproate and E-2-en-valproate on functional and morphological parameters of rat liver: I. biochemical, histological and pharmacokinetic studies
    • W. Loscher, U. Wahnschaffe, D. Honack, W. Wittfoht, and H. Nau: Effects of valproate and E-2-en-valproate on functional and morphological parameters of rat liver: I. biochemical, histological and pharmacokinetic studies. Epilepsy Res. 13, 187-198 (1992).
    • (1992) Epilepsy Res. , vol.13 , pp. 187-198
    • Loscher, W.1    Wahnschaffe, U.2    Honack, D.3    Wittfoht, W.4    Nau, H.5
  • 8
    • 0027157069 scopus 로고
    • Effects of valproic acid and E-2-en-valproate on functional and morphological parameters of rat liver: II. influence of phenobarbital comedication
    • W. Loscher, H. Nau, U. Wahnschaffe, D. Honack, C. Rundfeldt, W. Wittfoht, and U. Bojie: Effects of valproic acid and E-2-en-valproate on functional and morphological parameters of rat liver: II. influence of phenobarbital comedication. Epilepsy Res. 15, 113-131 (1993).
    • (1993) Epilepsy Res. , vol.15 , pp. 113-131
    • Loscher, W.1    Nau, H.2    Wahnschaffe, U.3    Honack, D.4    Rundfeldt, C.5    Wittfoht, W.6    Bojie, U.7
  • 9
    • 0027098905 scopus 로고
    • The valproic acid metabolite E-2-n-propyl-2-pentenoic acid does not induce spina bifida in the mouse
    • K. Ehlers, H. Sturje, H.-J. Merker, and H. Nau: The valproic acid metabolite E-2-n-propyl-2-pentenoic acid does not induce spina bifida in the mouse. Dev. Pharmacol. Ther. 19, 196-204 (1992).
    • (1992) Dev. Pharmacol. Ther. , vol.19 , pp. 196-204
    • Ehlers, K.1    Sturje, H.2    Merker, H.-J.3    Nau, H.4
  • 10
    • 0028309706 scopus 로고
    • Trans-2-ene-valproic acid is less behaviorally teratogenic than an equivalent dose of valproic acid in rats
    • J. E. Fisher, Jr., K. D. Acuff-Smith, M. A. Schilling, H. Nau, and C. V. Vorhees: Trans-2-ene-valproic acid is less behaviorally teratogenic than an equivalent dose of valproic acid in rats. Teratology 49, 479-486 (1984).
    • (1984) Teratology , vol.49 , pp. 479-486
    • Fisher Jr., J.E.1    Acuff-Smith, K.D.2    Schilling, M.A.3    Nau, H.4    Vorhees, C.V.5
  • 11
    • 0026749339 scopus 로고
    • 2(E)-valproate) in healthy male volunteers
    • 2(E)-valproate) in healthy male volunteers. Pharm. Weekbl. 14, 152-158 (1992).
    • (1992) Pharm. Weekbl. , vol.14 , pp. 152-158
    • Dusing, R.H.1
  • 12
    • 0019469772 scopus 로고
    • Human brain, plasma and cerebrospinal fluid concentration of sodium valproate after 72 hr of therapy
    • F. J. E. Vajda, G. A. Donnan, J. Phillips, and P. F. Bladin: Human brain, plasma and cerebrospinal fluid concentration of sodium valproate after 72 hr of therapy. Neurology 31, 486-487 (1981).
    • (1981) Neurology , vol.31 , pp. 486-487
    • Vajda, F.J.E.1    Donnan, G.A.2    Phillips, J.3    Bladin, P.F.4
  • 13
    • 0025827397 scopus 로고
    • Comparison of valproate concentrations in human plasma, CSF and brain tissue after administration of different formulations of valproate or valpromide
    • H. G. Wieser: Comparison of valproate concentrations in human plasma, CSF and brain tissue after administration of different formulations of valproate or valpromide. Epilepsy Res. 9, 154-159 (1991).
    • (1991) Epilepsy Res. , vol.9 , pp. 154-159
    • Wieser, H.G.1
  • 15
    • 0029095591 scopus 로고
    • Distribution of unsaturated metabolites of valproate in human and rat brain: Pharmacological relevance?
    • K. D. K. Adkison, G. A. Ojemann, R. L. Rapport, R. L. Dills, and D. D. Shen: Distribution of unsaturated metabolites of valproate in human and rat brain: pharmacological relevance? Epilepsia 36, 772-782 (1995).
    • (1995) Epilepsia , vol.36 , pp. 772-782
    • Adkison, K.D.K.1    Ojemann, G.A.2    Rapport, R.L.3    Dills, R.L.4    Shen, D.D.5
  • 16
    • 0344969992 scopus 로고
    • CSF and plasma pharmacokinetics: Relationship to mechanisms of action as exemplified by valproic acid in monkey
    • (J. S. Lockard and A. A. Ward, eds.), Raven Press, New York
    • R. H. Levy: CSF and plasma pharmacokinetics: relationship to mechanisms of action as exemplified by valproic acid in monkey. In "Epilepsy: A Window to Brain Mechanisms" (J. S. Lockard and A. A. Ward, eds.), pp. 191-200. Raven Press, New York, 1980.
    • (1980) Epilepsy: A Window to Brain Mechanisms , pp. 191-200
    • Levy, R.H.1
  • 17
    • 0020610769 scopus 로고
    • Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment
    • W. Loscher and H. Nau: Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment. J. Pharmacol. Exp. Ther. 226, 845-854 (1983).
    • (1983) J. Pharmacol. Exp. Ther. , vol.226 , pp. 845-854
    • Loscher, W.1    Nau, H.2
  • 18
    • 0030111301 scopus 로고    scopus 로고
    • Uptake of valproic acid into rat brain is mediated by a medium-chain fatty acid transporter
    • K. D. K. Adkison and D. D. Shen: Uptake of valproic acid into rat brain is mediated by a medium-chain fatty acid transporter. J. Pharmacol. Exp. Ther. 276, 1189-1200 (1996).
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 1189-1200
    • Adkison, K.D.K.1    Shen, D.D.2
  • 19
    • 0028806272 scopus 로고
    • Mechanism of valproic acid uptake by isolated rat brain microvessels
    • K. Naora and D. D. Shen: Mechanism of valproic acid uptake by isolated rat brain microvessels. Epilepsy Res. 22, 97-106 (1995).
    • (1995) Epilepsy Res. , vol.22 , pp. 97-106
    • Naora, K.1    Shen, D.D.2
  • 20
    • 0028299479 scopus 로고
    • Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system
    • K. D. K. Adkison, A. A. Artru, K. M. Powers, and D. D. Shen: Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system. J. Pharmacol. Exp. Ther. 268, 797-805 (1994).
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 797-805
    • Adkison, K.D.K.1    Artru, A.A.2    Powers, K.M.3    Shen, D.D.4
  • 21
    • 0000971339 scopus 로고
    • The passage of certain substances out of the cerebrospinal fluid
    • M. Pollay and H. Davson: The passage of certain substances out of the cerebrospinal fluid. Brain 86, 137-150 (1963).
    • (1963) Brain , vol.86 , pp. 137-150
    • Pollay, M.1    Davson, H.2
  • 23
    • 0025247074 scopus 로고
    • Cerebrospinal fluid dynamics and brain tissue composition following i.v. infusion of hypertonic saline in anesthetized rabbits
    • J. C. Foxworthy and A. A. Artru: Cerebrospinal fluid dynamics and brain tissue composition following i.v. infusion of hypertonic saline in anesthetized rabbits. J. Neurosurg. Anesthesiol. 2, 256-265 (1990).
    • (1990) J. Neurosurg. Anesthesiol. , vol.2 , pp. 256-265
    • Foxworthy, J.C.1    Artru, A.A.2
  • 24
    • 0022468223 scopus 로고
    • An electroencephalographic processing algorithm specifically intended for analysis of cerebral electrical activity
    • T. K. Gregory, and D. C. Pettus: An electroencephalographic processing algorithm specifically intended for analysis of cerebral electrical activity. J. Clin. Monit. 2, 190-197 (1986).
    • (1986) J. Clin. Monit. , vol.2 , pp. 190-197
    • Gregory, T.K.1    Pettus, D.C.2
  • 26
    • 0028944517 scopus 로고
    • Role of choroid plexus epithelium in the removal of valproic acid from the central nervous system
    • K. D. K. Adkison, A. A. Arthur, K. M. Powers, D. Nochlin, and D. D. Shen: Role of choroid plexus epithelium in the removal of valproic acid from the central nervous system. Epilepsy Res. 20, 185-192 (1995).
    • (1995) Epilepsy Res. , vol.20 , pp. 185-192
    • Adkison, K.D.K.1    Arthur, A.A.2    Powers, K.M.3    Nochlin, D.4    Shen, D.D.5
  • 27
    • 0029915261 scopus 로고    scopus 로고
    • Effect of para-aminohippurate on the efflux of valproic acid from the central nervous system of the rabbit
    • K. D. K. Adkison, K. M. Powers, A. A. Artru, and D. D. Shen: Effect of para-aminohippurate on the efflux of valproic acid from the central nervous system of the rabbit. Epilepsy Res. 23, 95-104 (1996).
    • (1996) Epilepsy Res. , vol.23 , pp. 95-104
    • Adkison, K.D.K.1    Powers, K.M.2    Artru, A.A.3    Shen, D.D.4
  • 28
    • 0343896569 scopus 로고
    • Chemical composition and secretory nature of fluids
    • (H. Davson, J. Landers, and A. Churchill, eds.), J. and A., Churchill, London
    • H. Davson: Chemical composition and secretory nature of fluids. In "Physiology of the Cerebrospinal Fluid" (H. Davson, J. Landers, and A. Churchill, eds.), pp. 33-54. J. and A., Churchill, London, 1970.
    • (1970) Physiology of the Cerebrospinal Fluid , pp. 33-54
    • Davson, H.1
  • 29
    • 0023779477 scopus 로고
    • Capillary gas chromatographic assay for valproic acid and its 2-desaturated metabolite in brain and plasma
    • R. L. O. Semmes and D. D. Shen: Capillary gas chromatographic assay for valproic acid and its 2-desaturated metabolite in brain and plasma. J. Chromatogr. 432, 185-197 (1988).
    • (1988) J. Chromatogr. , vol.432 , pp. 185-197
    • Semmes, R.L.O.1    Shen, D.D.2
  • 30
    • 0000974098 scopus 로고
    • Bulk flow and diffusion in the cerebrospinal fluid system of the goat
    • S. R. Heisey, D. Held, and J. R. Pappenheimer: Bulk flow and diffusion in the cerebrospinal fluid system of the goat. Am. J. Physiol. 203, 775-781 (1962).
    • (1962) Am. J. Physiol. , vol.203 , pp. 775-781
    • Heisey, S.R.1    Held, D.2    Pappenheimer, J.R.3
  • 31
    • 0343896566 scopus 로고
    • Comparing two or more groups
    • (J. Kuo, E. Fox, and S. McDonald, eds.), Jandel Scientific, San Rafael
    • J. Kuo, E. Fox, and S. McDonald: Comparing two or more groups. In "SigmaStat User's Manual" (J. Kuo, E. Fox, and S. McDonald, eds.), pp. 6-12 to 6-80. Jandel Scientific, San Rafael, 1992.
    • (1992) SigmaStat User's Manual , pp. 612-680
    • Kuo, J.1    Fox, E.2    McDonald, S.3
  • 32
    • 0015998620 scopus 로고
    • The effects of salicylate and probenecid on the cerebrospinal fluid transport of penicillin, aminosalicylic acid and iodide
    • R. Spector and A. V. Lorenzo: The effects of salicylate and probenecid on the cerebrospinal fluid transport of penicillin, aminosalicylic acid and iodide. J. Pharmacol. Exp. Ther. 188, 55-65 (1974).
    • (1974) J. Pharmacol. Exp. Ther. , vol.188 , pp. 55-65
    • Spector, R.1    Lorenzo, A.V.2
  • 33
    • 0021020420 scopus 로고
    • Brain metabolism: A perspective from the blood-brain barrier
    • W. M. Pardridge: Brain metabolism: a perspective from the blood-brain barrier. Physiol. Rev. 63, 1481-1535 (1983).
    • (1983) Physiol. Rev. , vol.63 , pp. 1481-1535
    • Pardridge, W.M.1
  • 34
    • 0015619481 scopus 로고
    • Is cerebrospinal fluid the major avenue for the removal of 5-hydroxyindoleacetic acid from the brain?
    • J. L. Meek and N. H. Neff: Is cerebrospinal fluid the major avenue for the removal of 5-hydroxyindoleacetic acid from the brain? Neuropharmacology 12, 497-499 (1973).
    • (1973) Neuropharmacology , vol.12 , pp. 497-499
    • Meek, J.L.1    Neff, N.H.2
  • 36
    • 25344449939 scopus 로고    scopus 로고
    • The effect of probenecid on extracellular and intracellular compartmentation of valproic acid in the rabbit brain as determined by microdialysis
    • J. L. Scism, K. M. Powers, A. A. Artru, and D. D. Shen: The effect of probenecid on extracellular and intracellular compartmentation of valproic acid in the rabbit brain as determined by microdialysis. Pharm. Res. 13, S456 (1996).
    • (1996) Pharm. Res. , vol.13
    • Scism, J.L.1    Powers, K.M.2    Artru, A.A.3    Shen, D.D.4
  • 37
    • 0025049614 scopus 로고
    • Transport of valproate and its effects on GABA uptake in astroglial primary culture
    • M. Nilson, E. Hanson, and L. Ronnback: Transport of valproate and its effects on GABA uptake in astroglial primary culture. Neurochem. Res. 15, 763-767 (1990).
    • (1990) Neurochem. Res. , vol.15 , pp. 763-767
    • Nilson, M.1    Hanson, E.2    Ronnback, L.3


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