Epoxyquinomicins A, B, C and D, new antibiotics from amycolatopsis II. Effect on type II collagen-induced arthritis in mice

Journal of Antibiotics

Volumn 50, Issue 11, 1997, Pages 906-911

  Matsumoto, Naoki ^a   Iinuma, Hironobu ^a   Sawa, Tsutomu ^a   Takeuchi, Tomio ^a   Hirano, Shin Ichi ^b   Yoshioka, Takeo ^b   Ishizuka, Masaaki ^c  

^a INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^b MERCIAN CORPORATION   (Japan)

^c Microbial Chemistry Research Foundation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CARRAGEENAN; COLLAGEN; EPOXYQUINOMICIN A; EPOXYQUINOMICIN B; EPOXYQUINOMICIN C; EPOXYQUINOMICIN D; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL;

EID: 0031465352     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.50.906     Document Type: Article

References (7)

1. MATSUMOTO, N.; T. TSUCHIDA, M. UMEKITA, N. KINOSHITA, H. IINUMA, T. SAWA, M. HAMADA & T. TAKEUCHI: Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities. J. Antibiotics 50: 900-905, 1997
2. TANAKA, T.; E. TSUKUDA, K. OCHIAI, H. KONDO, S. TESHIBA & Y. MATSUDA: EI-1511-3, -5 and EI-1625-2, I novel interleukin-1β converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. I. Taxonomy of producing strain, fermentation and isolation. J. Antibiotics 49: 1073-1078, 1996
3. TSUKUDA, E.; T. TANAKA, K. OCHIAI, H. KONDO, M. YOSHIDA, T. AGATSUMA, Y. SAITO, S. TESHIBA & Y. MATSUDA: EI-1507-1 and -2, novel interleukin-1β converting enzyme inhibitors produced by Streptomyces sp. E-1507. J. Antibiotics 49: 333-339, 1996
4. MATSUMOTO, N.; T. TSUCHIDA, R. SAWA, H. IINUMA, H. NAKAMURA, H. NAGANAWA, T. SAWA & T. TAKEUCHI: Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. III. Physico-chemical properties and structure determination. J. Antibiotics 50: 912-915, 1997
5. TRENTHAM, D. E.; A. S. TOWNES & A. H. KANG: Autoimmunity to type II collagens: an experimental model of arthritis. J. Exp. Med. 146: 857-864, 1977
6. HAYASHI, M.; K. MATSUNAGA, A. OKAHARA & S. MITA: Effect of bucillamine (SA96) on type II collagen induced arthritis in rats. J. Rheumatol. 18: 691-695, 1991
7. FUJISAWA, H.; T. NISHIMURA, A. MOTONAGA, Y. INOUE, K. INOUE, H. SUZUKA, H. YASHIFUSA, K. KIMURA & M. MURAMATSU: Effect of actarit on type II collagen-induced arthritis in mice. Arzneim-Forsch / Drug Res. 44: 64-68, 1994