Lack of genotypic resistance to stavudine (d4T) after 2 years of monotherapy

Antiviral Therapy

Volumn 2, Issue SUPPL.3, 1997, Pages 81-86

  Soriano, Vincent ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; LAMIVUDINE; STAVUDINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ANTIVIRAL ACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FEMALE; GENOTYPE; HUMAN; LEUKOPENIA; LONG TERM CARE; MALE; PRIORITY JOURNAL; REVIEW; VIRUS INHIBITION; VIRUS MUTATION;

EID: 0031465147     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (5)

1. Lin P, Samanta H, Rose R, Patick AK, Trimble J, Bechtold CM, Revie DR, Khan NC, Federici ME, Li H, Lee A, Anderson RE & Colonno RJ. Genotypic and phenotypic analysis of HIV type 1 isolates from patients on prolonged stavudine therapy. Journal of Infections Diseases 1994; 170:1157-1164.
2. Browne MJ, Mayer KH, Chafee SB, Dudley MN, Posner MR, Steinberg SM, Graham KK, Geleko SM, Zinner SH, Denman SL, Dunkle LM, Kaul S, McLaren C, Skowron G, Kouttab NM, Kennedy TA, Weitberg AB & Curt GA. 2′,3′-didehydro-3′-deoxythymidine (d4T) in patients with AIDS or AIDS-related complex: a phase I trial. Journal of Infections Diseases 1993; 167:21-29.
3. Murray H, Squires K, Weiss W, Stedz S, Sacks HS, Hassett J, Cross A, Anderson RE & Dunkle LM. Stavudine in patients with AIDS and AIDS-related complex: AIDS Clinical Trial Group 089. Journal of Infections Diseases 1995; 171(Supplement 2):123-130.
4. Griffith B, Brett-Smith H, Kim G, Mellors JW, Chacko TM, Garner RB, Cheng YC, Alcabes P & Friedland G. Effect of stavudine on HIV type 1 virus load as measured by quantitative mononuclear cell culture, plasma RNA, and immune complex-dissociated antigenemia. Journal of Infections Diseases 1996; 173:1252-1255.
5. Spruance S, Pavia A, Mellors J, Murphy R, Gathe J Jr, Stool E, Jemsek JG, Dellamonica P, Cross A & Dunkle L. Clinical efficacy of monotherapy with stavudine compared with zidovudine in HIV-infected, zidovudine experienced patients. Annals of Internal Medicine 1997; 126:355-363.